Staff Profile
Dr Rolando Berlinguer Palmini
Experimental Scientific Officer
- Email: rolando.berlinguer-palmini@ncl.ac.uk
- Telephone: 44(0)191 208 6813
- Address: The Bio-Imaging Unit
Second Floor
William Leech Building
缅北禁地
Medical School
Framlington Place
缅北禁地 Upon Tyne
NE2 4HH
I received a PhD in Physiological and Nutritional Sciences (2004) and a degree in Biological Sciences mastered in Molecular Biology (1998) from the University of Florence, Italy.
I worked four years at the department of Pharmacology (University of Florence) studying stroke and serotonin related mood disorders as well as working as nutritionist in a medical centre.
In 2008 I moved to London as Research Associate in the Optoneuro Project, first at Imperial College, and then at 缅北禁地. The aim of this multidisciplinary project was to develop an opto-electronic bionic eye for visually impaired retinitis pigmentosa patients. My role was to test the new opto-electronic devices in in-vitro biological models.
In 2013 I became a member of the Trevelyan Lab focusing on Epilepsy research and I worked as research associate on the project, very closely related (technically wise), to the Optoneuro project.
Since November 2015 I'm Experimental Scientific Officer at the focusing my work on super-resolution microscopy and advanced image analysis methods.
Most of my work is on a specific super-resolution microscopy technique called STED (Stimulated emission depletion) that allows up to 20nm resolution on the XY planes and 80nm resolution on the axial plane. This is roughly an order of magnitude more that standard confocal microscopy where anything smaller than or closer than 250nm cannot be resolved.
I am constantly trying new imaging protocols as well as doing comparison between different kinds of super-resolution microscopes currently in use at the Bio-Imaging facility such as the Zeiss Airyscan and the Visitech iSim.
In parallel with STED I am developing advanced image analsys methods and workflows to optimize data collection from images helping researchers to design imaging experiments from sample preparation to image collection and data analysis.
I was seminar leader module PED1003 (Pharmacology).
I regular train students and researchers on microscopy (theory, practice, hardware, software) and image analysis, as well as participating as speaker to microscopy workshops and seminars, nationally and internationally.
- Zorkau M, Albus CA, Berlinguer-Palmini R, Chrzanowska-Lightowlers ZMA, RN Lightowlers. . PNAS 2021, 118(6), e2008778118.
- Zorkau M, Proctor-Kent Y, Berlinguer-Palmini R, Hamilton A, Chrzanowska-Lightowlers ZM, Lightowlers RN. . In: Methods in Molecular Biology. Humana Press Inc, 2021, pp.159-181.
- White MG, Maheshwari RR, Anderson SJ, Berlinguer-Palmini R, Jones C, Richardson SJ, Rotti PG, Armour SL, Ding Y, Krasnogor N, Engelhardt JF, Gray MA, Morgan NG, Shaw JAM. . Journal of Clinical Endocrinology and Metabolism 2020, 105(5), 1366-1374.
- Prendergast L, McClurg UL, Hristova R, Berlinguer Palmini R, Greener S, Veitch K, Hernández-López I, Pasero P, Rico D, Higgins JMG, Gospodinov A, Papamichos-Chronakis M. . Nature Communications 2020, 11, 4534.
- Anzilotti C, Swan DJ, Boisson B, Deobagkar-Lele M, Oliveira C, Chabosseau P, Engelhardt KR, Xu X, Chen R, Alvarez L, Berlinguer-Palmini R, Bull KR, Cawthorne E, Cribbs AP, Crockford TL, Dang TS, Fearn A, Fenech EJ, de Jong SJ, Lagerholm C, Ma CS, Sims D, Van Den Berg B, Xu Y, Cant AJ, Kleiner G, Leahy TR, de laMorena MT, Puck JM, Shapiro RS, van der Burg M, Chapman JR, Christianson JC, Davies B, McGrath JA, Przyborski S, Santibanez Koref M, Tangye SG, Werner A, Rutter GA, Padilla-Parra S, Casanova JL, Cornall RJ, Conley ME, Hambleton S. . Nature Immunology 2019, 20, 350-361.
- Anderson R, Lagnado A, Maggiorani D, Walaszczyk A, Dookun E, Chapman J, Birch J, Salmonowicz H, Ogrodnik M, Jurk D, Proctor C, Correia-Melo C, Victorelli S, Fielder E, Berlinguer-Palmini R, Owens WA, Greaves L, Kolsky K, Parini A, Douin-Echinard V, LeBrasseur N, Arthur H, Tual-Chalot S, Schafer M, Roos C, Miller J, Robertson N, Mann J, Adams P, Tchkonia T, Kirkland J, Mialet-Perez J, Richardson GD, Passos J. . The EMBO Journal 2019, 38(5), e100492.
- Dong N, Berlinguer-Palmini R, Soltan A, Ponon N, O'Neil A, Travelyan A, Maaskant P, Degenaar P, Sun X. . Journal of Biophotonics 2018, 11(10), e201700358.
- Stathopoulou C, Gangaplara A, Mallett G, Flomerfelt FA, Liniany LP, Knight D, Samsel LA, Berlinguer-Palmini R, Yim J, Felizardo TC, Eckhaus MA, Edgington-Mitchell L, Martinez-Fabregas J, Zhu J, Fowler DH, van Kasteren SI, Laurence A, Bogyo M, Watts C, Shevach EM, Amarnath S. . Immunity 2018, 49(2), 247-263.e7.
- Park H, Han KS, Seo J, Lee J, Dravid SM, Woo J, Chun H, Cho S, Bae JY, An H, Koh W, Yoon BE, Berlinguer-Palmini R, Mannaioni G, Traynelis SF, Bae YC, Choi SY, Lee CJ. . Molecular Brian 2015, 8, 7.
- Mlinar B, Montalbano A, Baccini G, Tatini F, Berlinguer-Palmini R, Corradetti R. . Journal of General Physiology 2015, 145(3), 225-251.
- Felici R, Lapucci A, Cavone L, Pratesi S, Berlinguer-Palmini R, Chiarugi A. . Molecular Pharmacology 2015.
- Berlinguer-Palmini R, Narducci R, Merhan K, Dilaghi A, Moroni F, Masi A, Scartabelli T, Landucci E, Sili M, Schettini A, McGovern B, Maskaant P, Degenaar P, Mannaioni G. . PLoS One 2014, 9(9), 7.
- Berlinguer-Palmini R, Masi A, Narducci R, Cavone L, Maratea D, Cozzi A, Sili M, Moroni F, Mannaioni G. . PLoS One 2014, 8(11), e82180.
- Barrett John, Berlinguer-Palmini Rolando, Degenaar Patrick. . Visual Neuroscience 2014, 31(4-5), 345-354.
- Chaudet L, Neil M, Degenaar P, Mehran K, Berlinguer-Palmini R, Corbet B, Maaskant P, Rogerson D, Lanigan P, Bamberg E, Roska B. . In: Optogenetics: Optical Methods for Cellular Control. 2013, San Francisco, CA, USA: International Society for Optical Engineering.
- Al-Atabany W, McGovern B, Mehran K, Berlinguer-Palmini R, Degenaar P. . IEEE Transactions on Biomedical Engineering 2011, 60(3), 781-791.
- McGovern B, Drakakis EM, Neil N, O'Brian P, Corbett B, Berlinguer-Palmini R, Degenaar P. . In: IEEE Conference on Biomedical Circuits and Systems. 2011, San Diego, California, USA: IEEE.
- McGovern B, Palmini RB, Grossman N, Drakakis E, Poher V, Neil MAA, Degenaar P. . IEEE Transactions on Biomedical Circuits and Systems 2010, 4(6, part 2), 469-476.
- Degenaar P, McGovern B, Berlinguer-Palmini R, Vysokov N, Grossman N, Pohrer V, Drakakis E, Neil M. . In: IEEE Biomedical Circuits and Systems Conference (BioCAS 2010). 2010, Paphos, Cyprus: IEEE.
- Grossman N, Poher V, Grubb MS, Kennedy GT, Nikolic K, McGovern B, Palmini RB, Gong Z, Drakakis EM, Neil MAA, Dawson MD, Burrone J, Degenaar P. . Journal of Neural Engineering 2010, 7(1), 016004.
- Degenaar P, Grossman N, Berlinguer-Palmini R, McGovern B, Pohrer V, Drakakis E, Dawson M, Toumazou C, Burrone J, Nikolic K, Neil M. . In: IEEE Conference on Biomedical Circuits and Systems. BioCAS 2009. 2009, Beijing: IEEE Xplore.
- Berlinguer-Palmini R, Landucci E, Baccini G, Moroni F, Pellegrini-Giampietro D-E, Mannaioni G. Interplay between group I mGlu receptors and the endocannabinoid system in the CA1 hippocampal area: An electrophysiological study. In: 6th International Meeting on Metabotropic Glutamate Receptors. 2008, PERGAMON-ELSEVIER SCIENCE LTD.
- Mannaioni G, Orr AG, Hamill CE, Yuan H, Pedone KH, McCoy KL, Berlinguer-Palmini R, Junge CE, Yepes M, Hepler JR, Traynelis SF. Plasmin Potentiates Synaptic N-Methyl-D-aspartate Receptor Function in Hippocampal Neurons through Activation of Protease-activated Receptor-1. Normal 0 false false false IT ZH-CN X-NONE. J BIOL CHEM 2008, 283(29), 20600-11.
- Colombini B, Bagni MA, Berlinguer-Palmini R, Cecchi G. Crossbridge formation detected by stiffness measurements in single muscle fibres. Adv Exp Med Biol 2005, 565, 127-140.
- Bagni MA, Colombini B, Colomo F, Berlinguer-Palmini R, Cecchi G. Non cross-bridge stiffness in skeletal muscle fibres at rest and during activity. Adv Exp Med Biol 2005, 141-154.
- Bagni MA, Colombini B, Geiger P, Berlinguer-Palmini R, Cecchi G. Non-cross-bridge calcium-dependent stiffness in frog muscle fibers. Am J Physiol Cell Physiol 2004, 286)6).
- Bagni MA, Colombini B, Colomo F, Geiger P, Berlinguer-Palmini R, Cecchi G. Force response to stretches in activated frog muscle fibres at low tension. Adv Exp Med Biol 2003, 538, 429-438.