缅北禁地

Skip to main content

NuCore members

Professor Craig Robson

Professor of Molecular Urology

  • Telephone: +44 (0) 191 208 4426
  • Address: Translational and Clinical Research Institute,
    缅北禁地 Centre for Cancer,
    Paul O'Gorman Building,
    Medical School,
    Framlington Place,
    缅北禁地 upon Tyne,
    NE2 4HH
Background

Roles and Responsibilities

Executive Board, 缅北禁地 Centre for Cancer

Teaching and Training Committee (Chair), 缅北禁地 Centre for Cancer

Education Lead, Discovery of Medicines Theme

 

Qualifications

BSc (Hons) Sheffield University

PhD 缅北禁地

 

Previous Positions

Research Fellow, ICRF, IMM,Oxford University 1988-1993

Lecturer, Surgery, 缅北禁地 1993-2000

Senior Lecturer, Surgical Sciences, 缅北禁地 2000-2002

Reader in Prostate Cancer, Northern Institute for Cancer Research, 缅北禁地 2002-2005

 

Professional Body Membership

American Association for Cancer Research, British Association for Cancer Research, British Prostate Group, Society for Basic Urological Research, European Society for Urological Research, European Association of Urologists, European Association of Cancer Research

 

Committee Membership

Wales Cancer Bank Advisory Committee; BAUS Section of Academic Urology, Executive Committee; Prostate Cancer UK Advisory Board and Grants Panel

 

Editorial Board

Prostate Cancer; PLoS ONE, BJU International, Cancers, The Prostate

Research


Research Interests

I completed my PhD in 缅北禁地 in 1987 before moving to the Weatherall Institute of Molecular Medicine, Oxford University as a Research Fellow to study DNA repair and drug resistance mechanisms in cancer.

I took up an academic appointment in urological research in the Department of Surgery at 缅北禁地 in 1993 and established a group of basic scientists and urologists with a strong translational research focus, primarily in prostate cancer. I have been actively involved in initiating and leading several National and European prostate cancer research networks.

A molecular and cell biologist by training, I study cell signalling in cancer. My current research focusses on understanding the molecular mechanisms that drive the progression to therapy-resistant, metastatic prostate cancer. A central theme of my research programme is the androgen receptor signalling cascade where my group has identified many critical epigenetic alterations that influence receptor function and created relevant cell models, including induced pluripotent stem cells.  I have a number of ongoing biotech collaborations that involve the identification and assay development of biomarkers that distinguish indolent from aggressive prostate cancer.

 

Funding

Medical Research Council, Prostate Cancer UK, Prostate Cancer Research Centre, Cancer Research UK, Wellcome Trust, Astra Zeneca, BBSRC, European Union, JGWP Foundation.

 

Teaching

Education Lead, Discovery of Medicines Theme

Chair, Teaching and Training Committee, 缅北禁地 Centre for Cancer

 

Undergraduate Teaching

Module Leader BGM3024 - The Molecular Basis of Cancer

Module Leader BGM3065 – Biochemistry of Cancer and Chronic Diseases

Lecture on BMS3012 – Cancer Biology and Therapy

Lecture on BGM2002 - Biochemistry and Genetics of Signalling and the Cell Cycle

 

Postgraduate Teaching

Module Leader ONC8014 +ONC8097 - on-line teaching module for MSc in Oncology and Palliative Care


Publications

  • Articles

    • Garnham R, Geh D, Nelson R, Ramon-Gil E, Wilson L, Schmidt EN, Walker L, Adamson B, Buskin A, Hepburn AC, Hodgson K, Kendall H, Frame FM, Maitland N, Coffey K, Strand DW, Robson CN, Elliott DJ, Heer R, Macauley M, Munkley J, Gaughan L, Leslie J, Scott E. . Communications Biology 2024, 7(1), 276.
    • Adamson B, Brittain N, Walker L, Duncan R, Luzzi S, Rescigno P, Smith GR, McGill S, Burchmore RJS, Willmore E, Hickson I, Robson CN, Bogdan D, Jimenez-Vacas JM, Paschalis A, Welti J, Yuan W, McCracken SR, Heer R, Sharp A, de Bono J, Gaughan L. . Journal of Clinical Investigation 2023, 133(22), e169200.
    • Garnham R, Geh D, Nelson R, Ramon-Gil E, Wilson L, Schmidt EN, Walker L, Adamson B, Buskin A, Hepburn A, Hodgson K, Kendall H, Frame FM, Maitland NM, Coffey K, Robson CN, Elliott DJ, Heer R, Macauley MS, Munkley J, Gaughan L, Leslie J, Scott E. . bioRxiv 2023.
    • Singh P, Lanman NA, Kendall HLR, Wilson L, Long R, Franco OE, Buskin A, Miles CG, Hayward SW, Heer R, Robson CN. . Development 2023, 150(13), dev201328.
    • Alebady ZAH, Azizyan M, Nakjang S, Lishman-Walker E, Al-Kharaif D, Walker S, Choo HX, Garnham R, Scott E, Johnson KL, Robson CN, Coffey K. . Cancers 2023, 15(14), 3597.
    • Chan CD, Haagensen EJ, Tensaout HA, Rennie KJ, Gamie Z, Barry J, Birch MA, Gerrand CH, Nisar S, Robson CN, Lunec J, Rankin KS. . Oncology Letters 2021, 21(2), 158.
    • Hepburn AC, Curry EL, Moad M, Steele RE, Franco OE, Wilson L, Singh P, Buskin A, Crawford SE, Gaughan L, Mills IG, Hayward SW, Robson CN, Heer R. . Stem Cells Translational Medicine 2020, 9(7), 734-745.
    • Bainbridge A, Walker S, Smith J, Patterson K, Dutt D, Ng YM, Thomas HD, Wilson L, McCullough B, Jones D, Maan A, Banks P, McCracken SRC, Gaughan L, Robson CN, Coffey K. . Nucleic Acids Research 2020, 48(10), 5366-5382.
    • Hepburn AC, Steele RE, Veeratterapillay R, Wilson L, Kounatidou EE, Barnard A, Berry P, Cassidy JR, Moad M, El-Sherif A, Gaughan L, Mills IG, Robson CN, Heer R. . Oncogene 2019, 38, 4412-4424.
    • Kounatidou E, Nakjang S, McCracken SRC, Dehm SM, Robson CN, Jones D, Gaughan L. . Nucleic Acids Research 2019, 47(11), 5634-5647.
    • McClurg UL, Azizyan M, Dransfield DT, Namdev N, Chit NCTH, Nakjang S, Robson CN. . Oncotarget 2018, 9(38), 24992-25007.
    • McClurg UL, Chit NCTH, Azizyan M, Edwards J, Nabbi A, Riabowol KT, Nakjang S, McCracken SR, Robson CN. . Oncogene 2018, 37, 4679-4691.
    • McClurg UL, Nabbi A, Ricordel C, Korolchuk S, McCracken S, Heer R, Wilson L, Butler LM, Irving-Hooper BK, Pedeux R, Robson CN, Riabowol KT, Binda O. . British Journal of Cancer 2018, 118, 713-726.
    • Grey J, Jones D, Wilson L, Nakjang S, Clayton J, Temperley R, Clark E, Gaughan L, Robson C. . Oncotarget 2018, 9(3), 3922-3935.
    • Munkley J, McClurg UL, Livermore KE, Ehrmann I, Knight B, McCullagh P, McGrath J, Crundwell M, Harries LW, Leung HY, Mills IG, Robson CN, Rajan P, Elliott DJ. . Scientific Reports 2017, 7(1), 5249.
    • Moad M, Hannezo E, Buczacki SJ, Wilson L, ElSherif A, Sims D, Pickard R, Wright NA, Williamson SC, Turnbull DM, Taylor RW, Greaves L, Robson CN, Simons BD, Heer R. . Cell Reports 2017, 20(7), 1609-1622.
    • McClurg UL, Cork DMW, Darby S, Ryan-Munden CA, Nakjang S, Mendes-Cortes L, Treumann A, Gaughan L, Robson CN. . Nucleic Acids Research 2017, 45(4), 1793-1804.
    • Jones D, Noble M, Wedge SR, Robson CN, Gaughan L. . Scientific Reports 2017, 7, 40957.
    • Logan IR, McClurg UL, Jones DL, O'Neill DJ, Shaheen FS, Lunec J, Gaughan L, Robson CN. . Oncotarget 2016, 7(46), 74724-74733.
    • Kim S, Natesan S, Cornilescu G, Carlson S, Tonelli M, McClurg UL, Binda O, Robson CN, Markley JL, Balaz S, Glass KC. . Journal of Biological Chemistry 2016, 291(35), 18326-18341.
    • Munkley J, Vodak D, Livermore KE, James K, Wilson BT, Knight B, Mccullagh P, Mcgrath J, Crundwell M, Harries LW, Leung HY, Robson CN, Mills IG, Rajan P, Elliott DJ. . eBioMedicine 2016, 8, 103-116.
    • McClurg UL, Harle VJ, Nabbi A, Batalha-Pereira A, Walker S, Coffey K, Gaughan L, McCracken SRC, Robson CN. . Oncotarget 2015, 6(35).
    • Stockley J, Markert E, Zhou Y, Robson CN, Elliott DJ, Lindberg J, Leung HY, Rajan P. . Scientific Reports 2015, 5, 13426.
    • Munkley J, Livermore KE, McClurg UL, Kalna G, Knight B, McCullagh P, McGrath J, Crundwell M, Leung HY, Robson CN, Harries LW, Rajan P, Elliott DJ. . Oncoscience 2015, 2(9).
    • Wade MA, Jones D, Wilson L, Stockley J, Coffey K, Robson CN, Gaughan L. . Nucleic Acids Research 2015, 43(1), 196-207.
    • Cano LQ, Lavery DN, Sin S, Spanjaard E, Brooke GN, Tilman JD, Abroaf A, Gaughan L, Robson CN, Heer R, Mauri F, de Rooij J, Driouch K, Bevan CL. . Molecular Oncology 2015, 9(1), 295-308.
    • Munkley J, Oltean S, Vodák D, Wilson BT, Livermore KE, Zhou Y, Star E, Floros VI, Johannessen B, Knight B, McCullagh P, McGrath J, Crundwell M, Skotheim RI, Robson CN, Leung HY, Harries LW, Rajan P, Mills IG, Elliott DJ. . Oncotarget 2015, 6(33), 34358-34374.
    • Jones D, Wade M, Nakjang S, Chaytor L, Grey J, Robson CN, Gaughan L. . Oncotarget 2015, 6(30), 29782-29794.
    • O'Neill D, Jones D, Wade M, Grey J, Nakjang S, Guo W, Cork D, Davies BR, Wedge SR, Robson CN, Gaughan L. . Oncotarget 2015, 6(28), 26029-26040.
    • McClurg UL, Robson CN. . Oncotarget 2015, 6(12), 9657-9668.
    • Enshaei A, Robson CN, Edmondson RJ. . Annals of Surgical Oncology 2015.
    • Munkley J, Lafferty NP, Kalna G, Robson CN, Leung HY, Rajan P, Elliott DJ. . BMC Cancer 2015, 15, 9.
    • Rodriguez-Teja M, Gronau JH, Breit C, Zhang YZ, Minamidate A, Caley MP, McCarthy A, Cox TR, Erler JT, Gaughan L, Darby S, Robson C, Mauri F, Waxman J, Sturge J. . Journal of Pathology 2015, 235(4), 581-592.
    • Romeo MM, Ko B, Kim J, Brady R, Heatley HC, He J, Harrod CK, Barnett B, Ratner L, Lairmore MD, Martinez E, Luscher B, Robson CN, Henriksson M, Harrod R. . Virology 2015, 476, 271-288.
    • O'Neill DJ, Williamson SC, Alkharaif D, Monteiro ICM, Goudreault M, Gaughan L, Robson CN, Gingras AC, Binda O. . Epigenetics 2014, 9(7), 942-950.
    • Rajan P, Stockley J, Sudbery IM, Fleming JT, Hedley A, Kalna G, Sims D, Ponting CP, Heger A, Robson CN, McMenemin RM, Pedley ID, Leung HY. . BMC Cancer 2014, 14, 977.
    • McClurg UL, Summerscales EE, Harle VJ, Gaughan L, Robson CN. . Oncotarget 2014, 5(16), 7081-7092.
    • Munkley J, Rajan P, Lafferty NP, Dalgliesh C, Jackson RM, Robson CN, Leung HY, Elliott DJ. . OncoTarget 2014, 5(1), 131-139.
    • Coffey K, Rogerson L, Ryan-Munden C, Alkharaif D, Stockley J, Heer R, Sahadevan K, O'Neill D, Jones D, Darby S, Staller P, Mantilla A, Gaughan L, Robson CN. . Nucleic Acids Research 2013, 41(8), 4433-4446.
    • Heer R, Hepburn AC, Williamson SC, Kennedy A, El-Sherif A, Soomro NA, Brown CD, Robson CN. . Renal Failure 2013, 35(10), 1387-1391.
    • Townes CL, Ali A, Gross N, Pal D, Williamson SC, Heer R, Robson CN, Pickard R, Hall J. . The Prostate 2013, 73(14), 1529-1537.
    • Clark EL, Hadjimichael C, Temperley R, Barnard A, Fuller-Pace FV, Robson CN. . PLoS One 2013, 8(1), e54150.
    • Gaughan L, Stockley J, Coffey K, O'Neill D, Jones DL, Wade M, Wright J, Moore M, Tse S, Rogerson L, Robson CN. . Nucleic Acids Research 2013, 41(14), 6892-6904.
    • Bennett HL, Stockley J, Fleming JT, Mandal R, O'Prey J, Ryan KM, Robson CN, Leung HY. . BJU International 2013, 111(4), 672-682.
    • Burska UL, Harle VJ, Coffey K, Darby S, Ramsey H, O'Neill D, Logan IR, Gaughan L, Robson CN. . Journal of Biological Chemistry 2013, 288(45), 32641-32650.
    • Williamson SC, Mitter R, Hepburn AC, Wilson L, Mantilla A, Leung HY, Robson CN, Heer R. . British Journal of Cancer 2013, 109(4), 950-956.
    • Loddick SA, Ross SJ, Thomason AG, Robinson DM, Walker GE, Dunkley TPJ, Brave SR, Broadbent N, Stratton NC, Trueman D, Mouchet E, Shaheen FS, Jacobs VN, Cumberbatch M, Wilson J, Jones RDO, Bradbury RH, Rabow A, Gaughan L, Womack C, Barry ST, Robson CN, Critchlow SE, Wedge SR, Brooks AN. . Molecular Cancer Therapeutics 2013, 12(9), 1715-1727.
    • Moad M, Pal D, Hepburn AC, Williamson SC, Wilson L, Lako M, Armstrong L, Hayward SW, Franco O, Cates J, Fordham SE, Przyborski S, Carr-Wilkinson J, Robson CN, Heer R. . European Urology 2013, 64(5), 753-761.
    • de Jong A, Merkx R, Berlin I, Rodenko B, Wijdeven RHM, El Atmioui D, Yalcin Z, Robson CN, Neefjes JJ, Ovaa H. . ChemBioChem 2012, 13(15), 2251-2258.
    • Hepburn AC, Veeratterapillay R, Williamson SC, El-Sherif A, Sahay N, Thomas HD, Mantilla A, Pickard RS, Robson CN, Heer R. . PLoS One 2012, 7(11), e50690.
    • Williamson SC, Hepburn AC, Wilson L, Coffey K, Ryan-Munden CA, Pal D, Leung HY, Robson CN, Heer R. . PLoS One 2012, 7(11), e48944.
    • Coffey K, Blackburn TJ, Cook S, Golding BT, Griffin RJ, Hardcastle IR, Hewitt L, Huberman K, McNeill HV, Newell DR, Roche C, Ryan-Munden CA, Watson A, Robson CN. . PLoS One 2012, 7(10), e45539.
    • Elattar A, Warburton KG, Mukhopadhyay A, Freer RM, Shaheen F, Cross PA, Plummer ER, Robson CN, Edmondson RJ. . Gynecologic Oncology 2012, 124(1), 142-147.
    • Armstrong K, Ahmad I, Kalna G, Tan SS, Edwards J, Robson CN, Leung HY. . British Journal of Cancer 2011, 105(9), 1362-1369.
    • Shaheen FS, Znojek P, Fisher A, Webster M, Plummer R, Gaughan L, Smith GCM, Leung HY, Curtin NJ, Robson CN. . PLoS One 2011, 6(5), e20311.
    • Gaughan L, Stockley J, Wang N, McCracken S, Truemann A, Armstrong K, Shaheen F, Watt K, McEwan I, Wang C, Pestell RG, Robson CN. . Nucleic Acids Research 2011, 39(4), 1266-1279.
    • Rajan P, Dalgliesh C, Carling PJ, Buist T, Zhang CL, Grellscheid SN, Armstrong K, Stockley J, Simillion C, Gaughan L, Kalna G, Zhang MQ, Robson CN, Leung HY, Elliott DJ. . PLoS One 2011, 6(12), e29088.
    • Brooke GN, Culley RL, Dart DA, Mann DJ, Gaughan L, McCracken SR, Robson CN, Spencer-Dene B, Gamble SC, Powell SM, Wait R, Waxman J, Walker MM, Bevan CL. . Cancer Research 2011, 71(3), 914-924.
    • Blackwood JK, Williamson SC, Greaves LC, Wilson L, Rigas AC, Sandher R, Pickard RS, Robson CN, Turnbull DM, Taylor RW, Heer R. . Journal of Pathology 2011, 225(2), 181-188.
    • Johnson N, Bentley J, Wang LZ, Newell DR, Robson CN, Shapiro GI, Curtin NJ. . British Journal of Cancer 2010, 102(2), 342-350.
    • Lee JH, Jung C, Javadian-Elyaderani P, Schweyer S, Schutte D, Shoukier M, Karimi-Busheri F, Weinfeld M, Rasouli-Nia A, Hengstler JG, Mantilla A, Soleimanpour-Lichaei HR, Engel W, Robson CN, Nayernia K. . Cancer Research 2010, 70(11), 4569-4579.
    • Hori S, Jabbar T, Kachroo N, Vasconcelos J, Robson C, Gnanapragasam V. . Journal of Cancer Research and Clinical Oncology 2010, 137(2), 235-241.
    • Wiltshire C, Singh BL, Stockley J, Fleming J, Doyle B, Barnetson R, Robson CN, Kozielski F, Leung HY. . Molecular Cancer Therapeutics 2010, 9(6), 1730-1739.
    • Darby S, Murphy T, Thomas H, Robson CN, Leung HY, Mathers ME, Gnanapragasam VJ. . British Journal of Cancer 2009, 101(11), 1891-1899.
    • Rajan P, Dalgliesh C, Bourgeois CF, Heiner M, Emami K, Clark EL, Bindereif A, Stevenin J, Robson CN, Leung HY, Elliott DJ. . BMC Cell Biology 2009, 10(1), 82.
    • Logan IR, McNeill HV, Cook S, Lu X, Meek DW, Fuller-Pace FV, Lunec J, Robson CN. . Nucleic Acids Research 2009, 37(9), 2962-2973.
    • Sheach LA, Adeney EM, Kucukmetin A, Wilkinson SJ, Fisher AD, Elattar A, Robson CN, Edmondson RJ. . British Journal of Cancer 2009, 101(3), 498-503.
    • Rajan P, Elliott DJ, Robson CN, Leung HY. . Nature Reviews Urology 2009, 6(8), 454-460.
    • Rajan P, Gaughan L, Dalgliesh C, El-Sherif A, Robson CN, Leung HY, Elliott DJ. . Journal of Pathology 2008, 215(1), 67-77.
    • Clark EL, Coulson AC, Dalgliesh C, Rajan P, Nicol SM, Fleming S, Heer R, Gaughan L, Leung HY, Elliott DJ, Fuller-Pace FV, Robson CN. . Cancer Research 2008, 68(19), 7938-7946.
    • Sapountzi V, Logan IR, Nelson G, Cook S, Robson CN. . International Journal of Biochemistry & Cell Biology 2008, 40(2), 236-244.
    • Wilkinson S, Kucukmetin A, Cross P, Darby S, Gnanapragasam V, Calvert AH, Robson C, Edmondson RJ. . Human Pathology 2008, 39(8), 1197-1204.
    • Darby S, Cross SS, Brown NJ, Hamdy F, Robson CN. . Journal of Pathology 2008, 214(3), 394-404.
    • Rogerson LC, Darby S, Jabbar TA, Mathers ME, Leung HY, Robson CN, Sahadevan K, O'Toole KT, Gnanapragasam VJ. . BJU International 2008, 102(3), 364-370.
    • McCracken SRC, Ramsay A, Heer R, Mathers ME, Jenkins BL, Edwards J, Robson CN, Marquez R, Cohen P, Leung HY. . Oncogene 2008, 27(21), 2978-2988.
    • Rigas AC, Robson CN, Curtin NJ. . Oncogene 2007, 26(55), 7611-7619.
    • Heer, R., Robson, C. N., Shenton, B. K., Leung, H. Y. . Journal of Cellular Physiology 2007, 212(3), 572-578.
    • Sahadevan K, Darby S, Leung HY, Mathers ME, Robson CN, Gnanapragasam VJ. . Journal of Pathology 2007, 213(1), 82-90.
    • Darby S, Stockley J, Khan M, Robson CN, Leung HY, Gnanapragasam VJ. . Endocrine-Related Cancer 2007, 14(3), 613-624.
    • Logan, I., McNeill, H., Cook, S., Lu, X., Lunec, J., Robson, C.N. . Prostate 2007, 67(8), 900-906.
    • Darby, S., Sahadevan, K., Khan, M. M., Robson, C. N., Leung, H. Y., Gnanapragasam, V. J. . Oncogene 2006, 25(29), 4122-4127.
    • Heer, R., Collins, A., Robson, C.N., Shenton, B.K., Leung, H.K. . Journal of Cell Science 2006, 119(7), 1416-1424.
    • Logan IR, Gaughan L, McCracken SRC, Sapountzi V, Leung HY, Robson CN. . Molecular and Cellular Biology 2006, 26(17), 6502-6510.

  • Book Chapter

    • Moad M, Curry EL, Robson CN, Heer R. . In: Deepak A. Lamba, ed. Patient-Specific Stem Cells. Taylor & Francis, 2017, pp.177-194.

  • Editorial

    • Pal D, Moad M, Hepburn AC, Williamson SC, Robson CN, Heer R. . European Urology 2013, 64(5), 764-765.

  • Note

    • Johnson N, Bentley J, Wang L-Z, Newell DR, Robson CN, Shapiro GI, Curtin NJ. . British Journal of Cancer 2024, 131, 955.

  • Reviews

    • Hutton E, Scott E, Robson CN, Signoret N, Fascione MA. . Frontiers in Molecular Biosciences 2024, 11, 1390711.
    • Buskin A, Scott E, Nelson R, Gaughan L, Robson CN, Heer R, Hepburn AC. . Oncogene 2023, 42, 2417–2427.
    • Buskin A, Singh P, Lorenz O, Robson C, Strand DW, Heer R. . International Journal of Molecular Sciences 2022, 22(23), 13097.
    • Curry EL, Moad M, Robson CN, Heer R. . World Journal of Stem Cells 2015, 7(2), 461-469.
    • Fitzpatrick JM, Bellmunt J, Fizazi K, Heidenreich A, Sternberg CN, Tombal B, Alcaraz A, Bahl A, Bracarda S, Di Lorenzo G, Efstathiou E, Finn SP, Fossa S, Gillessen S, Kellokumpu-Lehtinen PL, Lecouvet FE, Oudard S, de Reijke TM, Robson CN, De Santis M, Seruga B, de Wit R. . European Journal of Cancer 2014, 50(9), 1617-1627.
    • Coffey K, Robson CN. . Journal of Endocrinology 2012, 215(2), 221-237.
    • McCracken S, Durkan G, Pickard R, Robson C. . Reviews in Clinical Gerontology 2010, 20(3), 193-204.
    • Sapountzi, V., Logan, I. R., Robson, C. N. . International Journal of Biochemistry & Cell Biology 2006, 38(9), 1496-1509.
    • Dorkin, T. J., Robson, C. N., Neal, D. E. . Journal of Pathology 1997, 183(4), 380-387.