缅北禁地

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Dr Marloes Peeters

Senior Lecturer

Background

I graduated from Eindhoven University of Technology (The Netherlands) with a degree in Chemistry & Chemical Engineering. For my PhD, I moved to research institute IMO/IMOMEC in Belgium where I was part of the BIOSensors group of Prof Wagner. After finishing my PhD, I continued as a postdoctoral researcher within the same group to develop a novel thermal detection method for measurements of both small molecules and proteins in complex matrices (for instance, human blood plasma or saliva). Since 2014 I am in the UK when I started as a postdoctoral researcher within the organic chemistry group at Queen Mary University of London, where my project focused on the electrochemical detection of enzyme catalysis. My independent research career commenced at Manchester Metropolitan in 2015, and I was promoted to Senior Lecturer in 2018. In 2019, I was appointed as Senior Lecturer at 缅北禁地 where I will continue to work in the area of biosensors and bioelectronics.  My research group focuses on development of novel sensor platforms, including synthesis of high affinity nanoparticles/polymers and use of thermal sensing strategies.

Research

My group is interested in developing new biosensing platforms for the detection of a wide variety of biomolecules, ranging from small molecules, to proteins, and even to large cells.

We focus on two specific areas:

  1. design of synthetic receptors for biomolecules of interest
  2. thermal detection methods to measure these biomolecules in biological samples

In terms of designing synthetic receptors, I have worked on polymeric receptors (Molecularly Imprinted Polymers) and DNA sensors (aptamers). With MIPs, the main focus has been on neurotransmitters, such as histamine, L-nicotine, serotonin, dopamine, and recent work on noradrenaline. In an ongoing project, this will be extended to cells and bacteria. DNA sensors were employed to detect peanut proteins, which is used for allergen screening in food samples.

My group has done extensive work on the use of the heat-transfer method (HTM) to detect neurotransmitters and proteins. Recently, collaborating with Maastricht Science Programme, a novel thermal detection method was reported.  This method, which we call thermal wave transport analysis (TWTA), focuses on the transport of thermal waves rather than keeping the temperature at a fixed value. Advantages include faster measurement time (<3 min), more straightforward analysis and increased signal-to-noise ratio. By significantly reducing the noise, it becomes possible to measure in complex samples. 

Funding:

EPSRC:  New Investigator Award: EP/R029296/1: £205,000, Development of a polymer-based sensing platform for the detection of antimicrobial resistance. Funded 2 year PDRA (Dr Hudson) and PhD student Mr Oliver Jamieson.

Impact Accelerator Account - Ideas 2 Innovation (£25,500 in total), cardiac biomarker sensing (with Dr Novakovic as co-I) and SARS-COV-2 immunity sensor (with Dr Payne as co-I)

EPSRC CDT funded studentship - PhD student Mr Jack Reeder (co-I Dr Elizabeth Heidrich & Dr Matthew Unthank from Northumbria University), with contribution from Cambridge Medical Technologies for company related activities

European Commission: Marie Curie International Fellow Dr Pankaj Singla (project TEMPER)

Rosetrees Trust Seedcorn Fund: Together with Dr Katarina Novakovic and Prof Ioakim Spyridopoulos, exploring our sensor platform for cardiac biomarker sensing

Cambridge Medical Technologies:

contract research (9 months, PDRA Francesco Mecozzi), which provided proof-of-concept for cardiovascular biomarker detection leading to a 3-year KTP through Innovate UK of which I am appointed as a consultant.

NC3Rs : PI of CRACK IT grant (£49,910) for project together with MIP Diagnostics.

9 month project (Dr Crapnell) dedicated to the development of sensors for the thermal detection of cardiovascular biomarkers. More information can be found on: https://www.nc3rs.org.uk/new-sensor-platform-combining-plastic-antibodies-simple-thermal-detection-0

RSC: various bursaries, mobility grants, and research fund starting academics

Bursary from Materials Division for organization Bioinspired Materials Symposium, RSC bursaries  to attend IUPAC General Assembly and Conference in Brazil and for summer students (Analytical Trust 2017, 2018 and 2019).

RSC Research Fund ( RF18-2811, £3,500) for starting academics. RSC research mobility (£4,500) for Dr Peeters to visit to Prof Gruber  in Brazil.

RSC research mobility hosting Dr Patrick Seumo (£5,000 - grant number M19-7489)

British Council/Newton Fund: Newton Bhabha placement

£10k for hosting visiting Indian scholar Pankaj Singla (2018)

Wellcome Trust: COVID-19 portal, co-I Dr Brendan Payne


Public engagement activities:

Royal Society of Chemistry outreach fund August 2020: £2,000 for "Microbes, the good, the bad, and the ugly" with Dr Crapnell at Manchester Metropolitan University

NC3Rs public engagement award (£1,000) for joint activity with Maastricht University

Royal Society: participation in Royal Society pairing scheme 2017, a funded week in Westminster, Dr Peeters was paired with civil servant Ben Rayner, senior policy advisor at the DEFRA.

Ingenious Award, Royal Academy of Engineering: £19,000 project together with Centre for Life and Manchester Metropolitan University to showcase how we can use waste materials as resins for 3D printing

Patents on new sensor platforms:

UK Patent application No.1906710.7, M. Peeters

K. Eersels, M. Peeters, A. Ethirajan, B. van Grinsven, W. De Ceuninck, P. Wagner,
European patent EP.13157264.6, 2014, Heat-transfer resistance based analysis of
bioparticles.

K. Eersels, M. Peeters, A. Ethirajan, B. van Grinsven, W. De Ceuninck, P. Wagner, US
patent 2014242605 A1, 2014, Heat-transfer resistance based analysis of
bioparticles.

M. Peeters, B. van Grinsven, W. De Ceuninck, P. Wagner, European patent
EP.14199245.3, 2014, Heat-transfer detection of proteins.

Publications
  • Jamieson O, Mecozzi F, Crapnell R, Battell W, Hudson A, Novakovic K, Sachdeva A, Canfarotta F, Herdes C, Banks C, Snyder H, Peeters M. . Physica Status Solidi A 2021, 218(13), 2100021.
  • Jamieson O, Betlem K, Mansouri N, Crapnell R, Vieira F, Hudson A, Banks C, Liauw C, Gruber J, Zubko M, Whitehead K, Peeters M. . Thermal Science and Engineering Progress 2021, 24, 100956.
  • Jamieson O, Betlem K, Mansouri N, Crapnell R, Vieira F, Hudson A, Banks C, Liauw C, Gruber J, Zubko M, Whitehead K, Peeters M. Electropolymerised molecularly imprinted polymers for the heat-transfer based detection of microorganisms: A proof-of-concept study using yeast. Thermal Science and Engineering Progress 2021, 24, 100956.
  • Wackers G, Cornelis P, Putzeys T, Peeters M, Tack J, Troost F, Doll T, Verhaert N, Wagner P. . ACS Sensors 2021, 6(1), 100-110.
  • Wackers G, Cornelis P, Putzeys T, Peeters M, Tack J, Troost F, Doll T, Verhaert N, Wagner P. Electropolymerized Receptor Coatings for the Quantitative Detection of Histamine with a Catheter-Based, Diagnostic Sensor. ACS Sensors 2021, 6(1), 100-110.
  • Hurst G, Peeters M, Tedesco S. . In: 2nd International Conference on Energy and Sustainable Futures (ICESF 2020). 2021, Springer.
  • Crapnell R, Jesadabundit W, García-Miranda Ferrari A, Dempsey-Hibbert N, Peeters M, Tridente A, Chailapakul O, Banks C. . Analytical Chemistry 2021, 93(14), 5931-5938.
  • Hudson A, Crapnell R, Betlem K, Jamieson O, Mecozzi F, Whitehead K, Eersels K, van Grinsven B, Cleij T, Peeters M. . In: ECS meeting. 2020, Montreal, Canada: Institute of Physics.
  • Eersels K, Lowdon J, Rogosic R, Heidt B, Campos R, Peeters M, Diliën H, van Grinsven B, Cleij T. . In: ECS meeting. 2020, Montreal, Canada: Institute of Physics.
  • Hudson A, Jamieson O, Mecozzi F, Rurack K, Peeters M. . In: 18th IMCS Meetings. 2020, Montreal, Canada: Institute of Physics.
  • Lowdon J, Dilien H, Singla P, Peeters M, Cleij T, van Grinsven B, Eersels K. . Sensors and Actuators B: Chemical 2020, 325, 128973.
  • Crapnell R, Dempsey-Hibbert N, Peeters M, Tridente A, Banks C. . Talanta Open 2020, 2, 100018.
  • Ahmed A, Hurst G, Peeters M, Tedesco S. . Research & Development in Material Science 2020, 14(1), 1505-1511.
  • Lowdon J, Ishikura H, Radchenko A, Arreguin-Campos R, Rogosic R, Heidt B, Jimenez-Monroy K, Peeters M, Dilien H, Eersels K, Cleij T, van Grinsven B. . ACS Omega 2020, 5(33), 21054–21066.
  • Hurst G, Brangeli I, Peeters M, Tedesco S. . Chemical Papers 2020, 74, 1647–1661.
  • Singla P, Garg S, Bhatti R, Peeters M, Singh O, Mahajan RK. . Journal of Molecular Liquids 2020, 317, 113816.
  • Betlem K, Canfarotta F, Raumbault R, Banks C, Eersels K, van Grinsven B, Cleij T, Crapnell R, Hudson A, Peeters M. . Analyst 2020, 145(16), 5419-5424.
  • Wackers G, Putzeys T, Peeters M, Van de Cauter L, Cornelis P, Wubbenhorst M, Tack J, Troost F, Verhaert N, Doll T, Wagner P. . Biosensors and Bioelectronics 2020, 158, 112152.
  • Peeters M, Linton P, Hidalgo-Bastida A. . Biomimetics 2019, 4(1), 4.
  • Betlem K, Mahmood I, Seixas RD, Sadiki I, Raimbault RLD, Foster CW, Crapnell RD, Tedesco S, Banks CE, Gruber J, Peeters M. . Chemical Engineering Journal 2019, 359, 505-517.
  • Betlem K, Kaur A, Hudson A, Crapnell R, Hurst G, Singla P, Zubko M, Tedesco S, Banks C, Whitehead K, Peeters M. . ACS Applied Biomaterials 2019, 2(9), 3790-3798.
  • Crapnell RD, Hudson A, Foster CW, Eersels K, Grinsven BV, Cleij TJ, Banks CE, Peeters M. . Sensors 2019, 19(5), 1204.
  • Jamieson O, Soares T, de Faria B, Hudson A, Mecozzi F, Rowley-Neale S, Banks C, Gruber J, Novakovic K, Peeters M, Crapnell R. . Chemosensors 2019, 8(1), 5.
  • Lowdon JW, Eersels K, Rogosic R, Heidt B, Dilien H, Redeker ES, Peeters M, van Grinsven B, Cleij TJ. . Sensors and Actuators B: Chemical 2019, 282, 137-144.
  • Hudson AD, Sola R, Ueta JT, Battell W, Jamieson O, Dunbar T, Macia B, Peeters M. . Biomimetics 2019, 4(1), 18.
  • Pankaj S, Singh O, Sharma S, Betlem K, Aswal V, Peeters M, Mahajan R. . ACS Omega 2019, 4(6), 11251-11262.
  • Crapnell R, Canfarotta F, Czulak J, Johnson R, Betlem K, Mecozzi F, Down M, Eersels K, van Grinsven B, Cleij T, Law R, Banks C, Peeters M. . ACS Sensors 2019, 4(10), 2838-2845.
  • Eersels K, Dilien H, Lowdon JW, Redeker ES, Rogosic R, Heidt B, Peeters M, Cornelis P, Lux P, Reutelingsperger CP, Schurgers LJ, Cleij TJ, van Grinsven B. . Nutrients 2018, 10(6), 751.
  • Canfarotta F, Czulak J, Betlem K, Sachdeva A, Eersels K, van Grinsven B, Cleij TJ, Peeters M. . Nanoscale 2018, 10(4), 2081-2089.
  • Betlem K, Down MP, Foster CW, Akthar S, Eersels K, Van Grinsven B, Cleij TJ, Banks CE, Peeters M. . MRS Advances 2018, 3(28), 1569-1574.
  • Lowdon JW, Alkirkit SMO, Mewis RE, Fulton D, Banks CE, Sutcliffe OB, Peeters M. . Analyst 2018, 143(9), 2002-2007.
  • Betlem K, Hoksbergen S, Mansouri N, Down M, Losada-Perez P, Eersels K, van Grinsven B, Cleij TJ, Kelly P, Sawtell D, Zubko M, Banks C, Peeters M. . Physics in Medicine 2018, 6, 1-8.
  • Steen Redeker E, Eersels K, Akkermans O, Royakkers J, Dyson S, Nurekeyeva K, Ferrando B, Cornelis P, Peeters M, Wagner P, Dilien H, Van Grinsven B, Cleij TJ. . ACS Infectious Diseases 2017, 3(5), 388-397.
  • Casadio S, Lowdon JW, Betlem K, Ueta JT, Foster CW, Cleij TJ, van Grinsven B, Sutcliffe OB, Banks CE, Peeters M. . Chemical Engineering Journal 2017, 315, 459-468.
  • van Grinsven B, Betlem K, Cleij TJ, Banks CE, Peeters M. . Journal of Molecular Recognition 2017, 30(1), e2563.
  • Dilien H, Peeters M, Royakkers J, Harings J, Cornelis P, Wagner P, Steen Redeker E, Banks CE, Eersels K, Van Grinsven B, Cleij TJ. . ACS Sensors 2017, 2(4), 583-589.
  • Vandenryt T, Van Grinsven B, Eersels K, Cornelis P, Kholwadia S, Cleij TJ, Thoelen R, De Ceuninck W, Peeters M, Wagner P. . Sensors 2017, 17(12), 2701.
  • Peeters MM, Van Grinsven B, Foster CW, Cleij TJ, Banks CE. . Molecules 2016, 21(5), 552.
  • Van Grinsven B, Eersels K, Akkermans O, Ellermann S, Kordek A, Peeters M, Deschaume O, Bartic C, Dilien H, Steen Redeker E, Wagner P, Cleij TJ. . ACS Sensors 2016, 1(9), 1140-1147.
  • Eersels K, Van Grinsven B, Vandenryt T, Jimenez-Monroy KL, Peeters M, Somers V, Puttmann C, Stein C, Barth S, Bos GMJ, Germeraad WTV, Dilien H, Cleij TJ, Thoelen R, Ceuninck WD, Wagner P. . Wiley - VCH Verlag GmbH & Co. KGaA 2015, 212(6), 1320-1326.
  • Peeters M, Van Grinsven B, Cleij TJ, Jimenez-Monroy KL, Cornelis P, Perez-Ruiz E, Wackers G, Thoelen R, De Ceuninck W, Lammertyn J, Wagner P. . ACS Applied Materials and Interfaces 2015, 7(19), 10316-10323.
  • Peeters M, Eersels K, Junkers T, Wagner P. . In: Molecularly Imprinted Catalysts: Principles, Syntheses, and Applications. Amsterdam: Elsevier Inc, 2015, pp.253-271.
  • Losada-Perez P, Mertens N, de Medio-Vasconcelos B, Slenders E, Leys J, Peeters M, Van Grinsven B, Gruber J, Glorieux C, Pfeiffer H, Wagner P, Thoen J. . Advances in Condensed Matter Physics 2015, 2015, 479318.
  • Wackers G, Vandenryt T, Cornelis P, Kellens E, Thoelen R, De Ceuninck W, Losada-Perez P, Van Grinsven B, Peeters M, Wagner P. . Sensors 2014, 14(6), 11016-11030.
  • Vandenbergh J, Peeters M, Kretschmer T, Wagner P, Junkers T. . Polymer 2014, 55(16), 3525-3532.
  • Cornelis P, Vandenryt T, Wackers G, Kellens E, Losada-Perez P, Thoelen R, De Ceuninck W, Eersels K, Drijkoningen S, Haenen K, Peeters M, Van Grinsven B, Wagner P. . Diamond and Related Materials 2014, 48, 32-36.
  • Losada-Perez P, Khorshid M, Hermans C, Robijns T, Peeters M, Jimenez-Monroy KL, Truong LTN, Wagner P. . Colloids and Surfaces B: Biointerfaces 2014, 123, 938-944.
  • Losada-Perez P, Jimenez-Monroy KL, Van Grinsven B, Leys J, Janssens SD, Peeters M, Glorieux C, Thoen J, Haenen K, De Ceuninck W, Wagner P. . Physica Status Solidi (A) Applications and Materials Science 2014, 211(6), 1377-1388.
  • Van Grinsven B, Eersels K, Peeters M, Losada-Perez P, Vandenryt T, Cleij TJ, Wagner P. . ACS Applied Materials and Interfaces 2014, 6(16), 13309-13318.
  • Peeters M, Kobben S, Jimenez-Monroy KL, Modesto L, Kraus M, Vandenryt T, Gaulke A, Van Grinsven B, Ingebrandt S, Junkers T, Wagner P. . Sensors and Actuators B: Chemical 2014, 203, 527-535.
  • Peeters M, Csipai P, Geerets B, Weustenraed A, Van Grinsven B, Thoelen R, Gruber J, De Ceuninck W, Cleij TJ, Troost FJ, Wagner P. . Analytical and Bioanalytical Chemistry 2013, 405(20), 6453-6460.
  • Peeters M, Troost FJ, Mingels RHG, Welsch T, Van Grinsven B, Vranken T, Ingebrandt S, Thoelen R, Cleij TJ, Wagner P. . Analytical Chemistry 2013, 85(3), 1475-1483.
  • Broeders J, Croux D, Peeters M, Beyens T, Duchateau S, Cleij TJ, Wagner P, Thoelen R, De Ceuninck W. . IEEE Sensors Journal 2013, 13(7), 2659-2665.
  • Croux D, Vangerven T, Broeders J, Boutsen J, Peeters M, Duchateau S, Cleij T, Deferme W, Wagner P, Thoelen R, De Ceuninck W. . Physica Status Solidi (A) Applications and Materials Science 2013, 210(5), 938-944.
  • Alenus J, Ethirajan A, Horemans F, Weustenraed A, Csipai P, Gruber J, Peeters M, Cleij TJ, Wagner P. . Analytical and Bioanalytical Chemistry 2013, 405(20), 6479-6487.
  • Geerets B, Peeters M, van Grinsven B, Bers K, de Ceuninck W, Wagner P. . Sensors 2013, 13(7), 9148-9159.
  • Peeters M, Troost FJ, Van Grinsven B, Horemans F, Alenus J, Murib MS, Keszthelyi D, Ethirajan A, Thoelen R, Cleij TJ, Wagner P. . Sensors and Actuators B: Chemical 2012, 171-172, 602-610.
  • Deng Z, Habraken GJM, Peeters M, Heise A, De With G, Sommerdijk NAJM. . Soft Matter 2011, 7(20), 9685-9694.
  • Broeders J, Duchateau S, Van Grinsven B, Vanaken W, Peeters M, Cleij T, Thoelen R, Wagner P, De Ceuninck W. . Physica Status Solidi (A) Applications and Materials Science 2011, 208(6), 1357-1363.
  • Habraken GJM, Peeters M, Thornton PD, Koning CE, Heise A. . Biomacromolecules 2011, 12(10), 3761-3769.
  • Habraken GJM, Peeters M, Dietz CHJT, Koning CE, Heise A. . Polymer Chemistry 2010, 1(4), 514-524.