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Staff Profile

Dr Matthew Leach

Director of the CBC

  • Telephone: +44 (0) 191 208 6725
  • Personal Website:
  • Address: Comparative Biology Centre
    Medical School
    Framlington Place
    缅北禁地
    缅北禁地 upon Tyne, UK, NE2 4HH
Background

Background

I undertook a degree in Zoology at the University of Southampton in 1992, which lead to an MSc in Applied Animal Behaviour & Welfare at the the University of Edinburgh in 1995. During this time I developed an interest in animal welfare and behaviour. This initially lead me into research investigating the welfare of captive elephants in the UK. Subsequently, I undertook a PhD in Laboratory Animal Welfare at the University of Birmingham which included research into euthanasia, husbandry and housing of laboratory animals. These research topics have formed the basis of my research career since. At the University of Bristol I undertook projects to develop a welfare benchmarking scheme for laboratory mice, investigate the standard of mouse welfare in the UK and to identify the most critical welfare issues affecting wildlife around the world. I continue to actively participate in these research areas. Since joining 缅北禁地 I have been involved in further research improving the welfare of laboratory, livestock and companion animal species.


Roles and Responsibilities

My research encompasses various aspects of laboratory, livestock and companion animal welfare. I lecture on multiple aspects of laboratory animals science, ethics and welfare and project design and statistics. I am the Director of the Comparative Biology Centre, which manages and cares for all of the animals that used in research at 缅北禁地.


Qualifications:

  • BSc (Hons) in Zoology from the University of Southampton
  • MSc in Applied Animal Behaviour & Welfare from the University of Edinburgh
  • PhD in Laboratory Animal Welfare from the University of Birmingham

Previous Positions:

  • Post-doctoral Research Associate at the University of Birmingham (2002)
  • Post-doctoral Research Associate at the University of Bristol (2002 to 2005)
  • Post-doctoral Research Associate at the 缅北禁地 (2005 to 2012)
  • Lecturer / Senior Lecturer (Animal Sciences) at 缅北禁地 (2012 to 2022)
  • Director of Comparative Biology Centre at 缅北禁地 (2023 onwards)

Memberships:

  • Consensus group on Carbon Dioxide Euthanasia of Laboratory Animals
  • Animal Welfare Science, Ethics & Law Veterinary Association (AWSELVA)
  • Editorial board member for 'Laboratory Animals' journal
  • Ethics committee for the Association for the Study of Animal Behaviour (ASAB)

Honours and Awards:

  • Significant contribution to the FELASA Animal Welfare Award 2007
  • Significant contribution to the Charles River Animal Welfare Prize 2012

Languages:

  • English
  • Some German

Informal Interests

  • Keeping dogs & cats
  • Cycling
  • Walking
  • Camping
  • Rugby
  • Technology

For a full list of my publications please see my




Research

Research Interests

Developing methods for assessing and alleviating post-procedure pain and distress in various animal species. Identifying and implementing novel manual and automated methods of assessing welfare, pain and distress in animals, particularly laboratory and companion animal species. Identifying, testing and implementing refinements to improve the welfare of a range of animal species. The development of educational materials to assist those who carry out procedures on animals in both veterinary practice and in animal-based research to refine the procedures that they carry out, improving welfare standards.


Other Expertise

Developing and implementing welfare benchmarking schemes for laboratory, pet and wild animals. The assessment of behaviour and welfare of a wide range of captive and wild animals. The use of experimental models and statistical analysis in animal-based research.


Keywords

Laboratory animal welfare, Companion animal welfare, Pain, Distress, Behaviour, Statistical analysis, Experimental design, Welfare benchmarking, Wildlife welfare

Teaching

Undergraduate Teaching:

  • ACE1041: Animal Science
  • ACE1057: Natural Science Research Impact
  • CMB2000: Essential Biomedical Research Skills
  • MST1204: Academic and Professional Skills for the Biosciences
  • PED3007: Drug Discovery and Development


Postgraduate Teaching:

  • PIL Courses at 缅北禁地
  • MMB8045: Applied Animal Behaviour and Welfare
  • BGM3062: Genetics of Development and its Disorders


External Workshops:

  • Research Animal Training (International) - Pain & Distress Workshops
  • Karolinska Institute (Sweden) - Experimental Design for In-Vivo Science
  • Cephalopod Research Institute (Italy) - Experimental Design for In-Vivo Science


Publications

  • Articles

    • Clarkson J, Leach MC, McKeegan DEF, Martin JE. . Scientific Reports 2023, 13, 4808.
    • Clarkson JM, Martin JE, Sparrey J, Leach MC, McKeegan DEF. . Proceedings of the Royal Society B: Biological Sciences 2023, 290(1997), 20222446.
    • Miller AL, Leach MC. . Laboratory Animals 2023, 57(3), 332-335.
    • Barney S, Dlay S, Crowe A, Kyriazakis I, Leach M. . Scientific Reports 2023, 13, 4499.
    • Ginger L, Aube L, Ledoux D, Borot M, David C, Bouchond M, Leach M, Durand D, de Boyer des Roches A. . Applied Animal Behaviour Science 2023, 264, 105951.
    • Prescott MJ, Leach MC, Truelove MA. . F1000 Research 2022, 11, 272.
    • Miller AL, Clarkson J, Quigley C, Neville V, Krall C, Geijer-Simson A, Flecknell PA, Leach MC. . Frontiers in Veterinary Science 2022, 9, 782486.
    • Clarkson JM, McKeegan DEF, Sparrey J, Marchesi F, Leach MC, Martin JE. . Frontiers in Veterinary Science 2022, 9, 834478.
    • Robinson LM, Waran NK, Handel I, Leach MC. . Applied Animal Behaviour Science 2021, 236, 105268.
    • Truelove MA, Martin JE, Langford FM, Leach MC. . Scientific Reports 2020, 10, 20402.
    • Pinho RH, Leach MC, Minto BW, Del Lama Rocha F, Luna SPL. . PLoS ONE 2020, 15(10), e0240605.
    • Clarkson JM, Leach MC, Flecknell PA, Rowe C. . Proceedings of the Royal Society B: Biological Sciences 2020, 287(1933), 1636.
    • Dai F, Leach M, MacRae AM, Minero M, Dalla-Costa E. . Animals 2020, 10(5), 781-788.
    • Campos-Luna I, Miller A, Beard A, Leach M. . Scientific Reports 2019, 9, 10249.
    • Descovich KA, Richmond SE, Leach MC, Buchanan-Smith HM, Flecknell P, Framingham DAH, Witham C, Gates MC, Vick SJ. . ALTEX 2019, 36(4), 535-554.
    • Clarkson JM, Dwyer DM, Flecknell PA, Leach MC, Rowe C. . Scientific Reports 2018, 8(1), 2448.
    • Robinson LM, Waran NK, Leach MC, Morton FB, Paukner A, Lonsdorf E, Handel I, Wilson VAD, Brosnan SF, Weiss A. . Applied Animal Behaviour Science 2018, 204, 134-134.
    • Costa ED, Pascuzzo R, Leach MC, Dai F, Lebelt D, Vantini S, Minero M. Can grimace scales estimate the pain status in horses and mice? A statistical approach to identify a classifier. PLoS ONE 2018, 13(8), e0200339.
    • Reigwart ML, Schoemaker NJ, Pascuzzo R, Leach MC, Stodel M, deNies L, Hendriksen CFM, vanderMeer M, Vinke CM, vanZeeland YRA. . PLoS ONE 2017, 12(11), e0187986.
    • Malik A, Leach M. . Veterinary Nursing Journal 2017, 32(4), 103-108.
    • Di Giminiani P, Nasirahmadi A, Malcolm EM, Leach MC, Edwards SA. . Physiology and Behaviour 2017, 182, 69-76.
    • Viscardi AV, Hunniford M, Lawlis P, Leach M, Turner PV. . Frontiers in Veterinary Science 2017, 4, 51.
    • Robinson LM, Altschul DM, Wallace EK, Úbeda Y, Llorente M, Marchanda Z, Slocombe KE, Leach MC, Waran NK, Weiss A. . Applied Animal Behaviour Science 2017, 191, 90-97.
    • Di Giminiani P, Edwards SA, Malcolm EM, Leach MC, Herskin MS, Sandercock DA. . Scientific Reports 2017, 7, 4827.
    • Miller AL, Kitson GL, Skalkoyannis B, Flecknell PA, Leach MC. . Applied Animal Behaviour Science 2016, 181, 160-165.
    • Dalla-Costa E, Stucke D, Dai F, Minero M, Leach MC, Lebel D. . Animals 2016, 6(8).
    • Miller AL, Golledge HDR, Leach MC. . PLoS ONE 2016, 11(11), e0166652.
    • Miller A, Leach MC. . Laboratory Animals 2016, 50(4), 305-307.
    • Di Giminiani P, Brierley VLMH, Scollo A, Gottardo F, Malcolm EM, Edwards SA, Leach MC. . Frontiers in Veterinary Science 2016, 3, 100.
    • Robinson LM, Waran NK, Leach MC, Morton FB, Paukner A, Lonsdorf E, Handel I, Wilson VAD, Brosnan SF, Weiss A. . Applied Animal Behaviour Science 2016, 181, 145-151.
    • Ellen Y, Flecknell P, Leach M. . PLoS One 2016, 11(9), e0161941.
    • Thomas AA, Miller AL, Roughan JV, Malik A, Haylor KE, Sanderson C, Flecknell PA, Leach M. . PLOS One 2016, 11(10), e0163909.
    • Whittaker AL, Leach MC, Preston FL, Lymn KA, Howarth GS. . Laboratory Animals 2016, 50(2), 108-118.
    • McLennan KM, Rebelo CJB, Corke MJ, Holmes MA, Leach MC, Constantino-Casas F. . Applied Animal Behaviour Science 2016, 176, 19-26.
    • Davies GF, Greenhough BJ, Hobson-West P, Kirk RGW, Applebee K, Bellingan LC, Berdoy M, Buller H, Cassaday HJ, Davies K, Diefenbacher D, Druglitro T, Escobar MP, Friese C, Herrmann K, Hinterberger A, Jarrett WJ, Jayne K, Johnson AM, Johnson ER, Konold T, Leach MC, Leonelli S, Lewis DI, Lilley EJ, Longridge ER, McLeod CM, Miele M, Nelson NC, Ormandy EH, Pallett H, Poort L, Pound P, Ramsden E, Roe E, Scalway H, Schrader A, Scotton CJ, Scudamore CL, Smith JA, Whitfield L, Wolfensohn S. . PLoS ONE 2016, 11(7), e0158791.
    • McLennan KM, Rebelo CJB, Corke MJ, Holmes MA, Leach MC, Constantino-Casas F. . Applied Animal Behaviour Science 2016, 179, 105-107.
    • Guesgen MA, Beausoleil NJ, Leach M, Minot EO, Stewart M, Stafford KJ. . Behavioural Processes 2016, 132, 49-56.
    • DiGiminiani P, Sandercock DA, Malcolm EM, Leach MC, Herskin MS, Edwards SA. . Physiology & Behavior 2016, 165, 119-126.
    • Sneddon LU, Leach MC. . Animal Sentience 2016, 1(3), 1-4.
    • Miller AL, Leach MC. . Laboratory Animals 2015, 49(2), 117-120.
    • Miller AL, Leach MC. . PLoS ONE 2015, 10(9), e0136000.
    • Miller AL, Kitson GL, Skalkoyannis B, Leach MC. . Applied Animal Behaviour Science 2015, 172, 58-62.
    • Hawkins P, Clutton RE, Dennison N, Guesgen M, Leach M, Sharpe F, Simmons H, Smith AJ, Webster J, Weyer U. . Animal Technology and Welfare 2014, 13(1), 43-56.
    • Dalla Costa E, Minero M, Lebelt D, Stucke D, Canali E, Leach MC. . PLoS ONE 2014, 9(3).
    • Leach MC, Klaus K, Miller AL, Scotto di Perrotolo M, Sotocinal SG, Flecknell PA. . PloS One 2012, 7(4), e35656.
    • Brieuc V, Flecknell P, Miller A, Thomas A, Leach M. . STAL 2012, 38(3), 33-45.
    • Keating SCJ, Thomas AA, Flecknell PA, Leach MC. . PLoS One 2012, 7(9), e44437.
    • Thomas AA, Leach MC, Flecknell PA. . Laboratory Animals 2012, 46(1), 71-76.
    • Coulter CA, Flecknell PA, Leach MC, Richardson CA. . BMC Veterinary Research 2011, 7, 12.
    • Farnworth MJ, Walker JK, Schweizer KA, Chuang C-L, Guild S-J, Barrett CJ, Leach MC, Waran NK. . Animal Welfare 2011, 20(2), 225-237.
    • Leach MC, Coulter CA, Richardson CA, Flecknell PA. . PLoS One 2011, 6(3), e13347.
    • Miller AL, Flecknell PA, Leach MC, Roughan JV. . Applied Animal Behaviour Science 2011, 131(3-4), 138-144.
    • ScottodiPerrotolo M, Miller AL, Leach MC, Flecknell PA. . STAL 2010, 36(4), 49-58.
    • Leach MC, Bailey HE, Dickinson AL, Roughan JV, Flecknell PA. . Laboratory Animals 2010, 44(1), 59-65.
    • Dickinson AL, Leach MC, Flecknell PA. . Laboratory Animals 2009, 43(1), 11-16.
    • Leach MC, Allweiler S, Richardson C, Roughan JV, Narbe R, Flecknell PA. . Research in Veterinary Science 2009, 87(2), 336-347.
    • Leach MC, Thornton PD, Main DCJ. . Animal Welfare 2008, 17(2), 161-170.
    • Leach MC, Main DCJ. . Animal Welfare 2008, 17(2), 171-187.
    • Richardson CA, Niel LE, Leach MC, Flecknell PA. . Laboratory Animals 2007, 41(1), 46-54.
    • Leach MC, Bowell VA, Allan TF, Morton DB. . Animal Welfare 2004, 13(s1), 77-86.
    • Leach MC, Morton DB. . ANZCCART Newsletter 2004, 17, 1-4.
    • Raj ABM, Leach MC, Morton DB. . Comparative Medicine 2004, 54(5), 470-471.
    • Leach MC, Bowell VA, Allan TF, Morton DB. . Veterinary Record 2002, 150(26), 808-815.
    • Leach MC, Bowell VA, Allan TF, Morton DB. . Comparative Medicine 2002, 52(6), 572.
    • Leach MC, Bowell VA, Allan TF, Morton DB. . Comparative Medicine 2002, 52(3), 249-257.
    • Leach MC, Bowell VA, Allan TF, Morton DB. Aversion to gaseous anesthesia in rats and mice. Comparative Medicine 2002, 52(6), 498.
    • Leach MC, Ambrose N, Morton DB. . Journal of Applied Animal Welfare Science 2000, 3(2), 81-91.
    • Leach MC, Waran N, Young RJ. Olfactory enrichment for asian elephants: Is it as good as it smells?. International Zoo News 1998, 45, 285-291.
    • Leach MC. Animal Training – A controversial form of enrichment. Ratel 1997, 25, 49-58.

  • Book Chapters

    • Dennison T, Leach MC. . In: Pullen, S, ed. Ethics, Animal Law and the Veterinary Nurse. Oxford: Elsevier, 2006, pp.103-116.
    • Morton DB, Ambrose N, Leach MC, Kelly J, Poirier G. . In: Balls M, van Zeller AM, Halder ME, ed. Progress in the reduction, refinement and replacement of animal experimentation: proceedings of the 3rd World Congress on Alternatives and Animal Use in the Life Sciences, held in Bologna, Italy, from 29 August to 2 September 1999. Amsterdam: Elsevier, 2000, pp.1083-1093.
    • Leach MC. Practical environmental enrichment for elephants. In: Field D, Young RJ, ed. Zoo Enrichment Guidelines. Association of British Wild Animal Keepers, 1997.

  • Conference Proceedings (inc. Abstracts)

    • Harper S, Mehrnezhad M, Leach M. . In: 2022 IEEE European Symposium on Security and Privacy Workshops (EuroS&PW). 2022, Genoa, Italy: IEEE.
    • Di Giminiani P, Malcolm EL, Leach MC, Herskin MS, Sandercock DA, Edwards SA. . In: 24th International Pig Veterinary Society Congress. 2016, Dublin, Ireland.
    • Di Giminiani P, Sandercock DA, Malcolm EL, Leach MC, Edwards SA. . In: RSPCA/AHVLA Meeting on Welfare of Agricultural Animals in Research. 2015, England, UK.
    • Rocha GS, Roughan J, Leach M, Flecknell P, Ingram CD, Brandt K. . In: II International Symposium on Medicinal and Nutraceutical Plants. 2013, New Delhi, India: International Society for Horticultural Science.
    • Leach MC, Klaus K, Miller AL, Scotto di Perrotolo M, Sotocinal SG, Flecknell PA. . In: ALTEX: 8th World Congress. 2012, Montreal, Canada: Springer Spektrum.
    • Leach MC, Thornton PD, Main DCJ. . In: 9th FELASA Symposium on Internationalisation and harmonisation of laboratory animal care and use issues. 2006, Nantes, France: Laboratory Animals Ltd.

  • Editorial

    • Flecknell P, Leach M, Bateson M. . Pain 2011, 152(5), 963-964.

  • Letter

    • Sneddon LU, Lopez-Luna J, Wolfenden DCC, Leach MC, Valentim AM, Steenbergen PJ, Bardine N, Currie AD, Broom DM, Brown C. . Journal of Experimental Biology 2017, 220(17), 3192-3194.

  • Report

    • Hawkins P, Playle L, Golledge H, Leach M, Banzett R, Coenen A, Cooper J, Danneman P, Flecknell P, Kirkden R, Niel L, Raj M. . 缅北禁地 upon Tyne, UK: NC3Rs, 2006.

  • Reviews

    • Miller AL, Leach MC. . Veterinary Clinics of North America: Exotic Animal Practice 2023, 26(1), 187-199.
    • McLennan KM, Miller AL, Dalla Costa E, Stucke D, Corke MJ, Broom DM, Leach MC. . Applied Animal Behaviour Science 2019, 217, 1-15.
    • Descovich KA, Wathan J, Leach MC, Buchanan-Smith HM, Flecknell P, Framingham D, Vick SJ. . ALTEX 2017, 34(3), 409-429.
    • Sneddon LU, Elwood RW, Adamo SA, Leach MC. . Animal Behaviour 2014, 97, 201-212.