缅北禁地

Key roles:

Director of Engagement & Place, Faculty of Medical Sciences

Director of Engagement, School of Dental Sciences (2019-2023)

Deputy Director of Examination and Assessment -preclinical, School of Dental Sciences

Chair of the Board of Examiners for Stage 1 BDS

Co-lead Faculty Fitness to Practise

Qualifications:

Senior Fellowship of the HEA

National teaching award by completion of CASAP

BBSRC funded Ph.D. in Molecular Nutrition and Biochemistry, Institute for Cell and Molecular Biosciences. Supervisor: Professor Dianne Ford. Title of thesis: Genetic influences on inter-individual variation in soyabean isoflavone absorption and metabolism.

BSc Hons Pharmacology, 缅北禁地

Funding:

Monash University- 缅北禁地 PhD Exchange programme. L Wakeling, N Jakubovics and M Piper. The role of nutrition in Drosophila immunity. 2018-2020.

NIHR 缅北禁地 Biomedical Research Centre (BRC) 3 Year PhD Studentship Funding. J Taylor, R Valentine, L Wakeling and P Preshaw. An investigation of the credentials of Sirt2 as an age-related biomarker for periodontitis. 2017-2020.

Rank Prize Vacation Scholarship. Modulation of gustatory receptor gene expression in an inflammatory immune response. L Wakeling. Jul 2015.

University Education Development Fund:

• L Wakeling and J Ellis. Validation by dental students of the alignment of our Educational Strategy to their learning experience. May 2019-Jan 2021

• L Wakeling, M Thomason, G Watkins (NUSU), J Barton (NUSU) and M Lintern (Careers) Development of professional learning through student representation. May 2017-Jun 2018.

• L Wakeling and M Vernon (NUIT). Context Café: course integration sessions to engage Dental Surgery undergraduates with the basic sciences captured by notebook technology. May 2015- Jun 2017

Faculty Education Research Development and Practice Fund:

• L Wakeling and P Waterhouse. Equality, Diversity and Inclusion in the Dental School’s student representation system. Apr 2019-Feb 2020

• L Wakeling, M Harper (Stage 4 BDS UG), H Bateman, P Blaylock, (BDA) and J Barton (NUSU). Pilot and evaluation of an Advanced ncl like workshop ‘Professional Learning through student representation’. Dec 2018- May 2020

• L Wakeling and J Barton (NUSU), Development of professional learning through student representation. Nov 2017- Dec 2018

• E Tullo (SBMS) and L Wakeling Symposium and development of Special Interest Group. Apr 2019

• L Wakeling and A Iannetti (Pharmacy) Tackling the common issues of the Faculty’s Student Academic Representation system in a half-day event. Jul 2018

• L Wakeling and J Ellis. Educating Dental Educators to do Education Research Apr 2018

• L Wakeling, J Brown (SBMS) an J Stewart (SME), Evaluation of Context Café, a session which allows Stage 2 Biochemistry students to contextualise learning in their degree programme and beyond. Apr 2017- Jan 2018

• E Tullo (SBMS), L Wakeling, Laura Greaves (ION) and Rose Gilroy (APL) Inclusive research with students and members of the public: How can we best evaluate innovative teaching about ageing? Aug 2017- Aug 2019

• R Valentine (FMS) L Wakeling, L Ferrie (FMS), C Guilding (FMS), A Schartner (HASS), Student induction into the University- does it work? 2016

Google scholar:  

Research interests:

My main research interest is in the effect of nutrition on epigenetics (modifications to the genome such as DNA methylation) and ultimately the effect this has in healthy ageing and lifespan.

My research focuses on dietary polyphenols; from studying genetic differences that may influence variation in polyphenol metabolism, to investigating the ability of these polyphenols to mimic the beneficial effects seen with dietary restriction on ageing in endothelial and epithelial cell models.

A model organism to assess the effect of diet on DNA methylation and lifespan is the honeybee. Honeybees have similar methylation machinery to humans and it has been shown that a change in diet early in a bee’s life can dramatically alter the life outcome of the bee (lifespan and reproductive capacity are hugely altered); changes in DNA methylation also coincide with these dietary effects. We have shown that a protein, Sir2, which is involved in the lifespan response to dietary restriction, is also affected in the honeybee by diet. I am also interested in the taste receptor expression in the honeybee and bumble bee and the response to dietary interventions. 

Engagement in research interests: I am also working on access to health care and through co-development with 缅北禁地 Foodbank on integrating healthcare services, organised delivery of a mobile dental unit and conducted research to evaluate barriers to accessing care and costs of delivering care in this way.

Education research interests:

Ageing and dementia education and involving older people in the design, development and delivery of an innovative module on ageing for undergraduates. Older people worked with us to design deliver and through Participatory Action Research, evaluate the module.

Context Café: course integration session to engage Dental Surgery undergraduates with the basic sciences. Caries Cafe:development of the World cafe method to construct, integrate and consolidate Caries teaching.

Opportunity for professional learning through student representation: 缅北禁地’s Academic Representation System enables its students to feedback on and enhance their learning experience. Many of the skills that students develop as Representatives echo expected General Dental Council professional standards (e.g. dealing with complaints, raising concern, effective management and leadership). The Professional Learning through Representation programme has been co-developed with students and NUSU to provide students with an opportunity to build on their Academic Representation experience and develop related professional skills.

Student learning experience of delivering oral health education across the region and preventative screening at a local foodbank.

Stage 1 and 2 Dental Surgery BDS programme, School of Dental Sciences: 

Cell Biology course lead (Stage 1) and Blood theme-lead for Dental Physiology. I also teach across Cell Physiology (Stage 1), Metabolism and Homeostasis (Stage 1), Microbiology for Dentists (Stage 2) and Nutrition and Diet (Stage 2).

Course lead for Orientation and Study Skills (Stage 1). Including development and delivery of Context Café – a basic sciences integration method in induction week.

Caries Café (Stage 3): Development and delivery of an integration method for caries that is taught across the entire BDS programme.

Wider university teaching: 

Seminar leader for Stage 1 Pharmacology, School of Biomedical Sciences

Lecturer: BGM3063 Epigenetics

BGM3063 Context Café 

Student supervision:

Supervision and training in research of undergraduate, MSci, MRes and PhD students

Supervision and training in research of JobsOC student internships

Vice Chancellors Education Excellence Award (2019)

Collaborative Award for Teaching Excellence (2016)

• Articles

  • Wahono NA, Wakeling LA, Dirks W, Banks DA, Shepherd TJ, Ford D, Valentine RA. . Frontiers in Oral Health 2023, 4, 1119086.
  • Tullo E, Wakeling L, Pearse R, Kheng Khoo T, Teodorczuk A. . BMJ Open 2023, 13(11), e077028.
  • Wakeling L, Blaylock P, Harper M, Trevor M, Murphy H, Barton J, Bateman H. . British Dental Journal 2022, 232, 867-873.
  • Forster F, Tullo E, Wakeling l, Gilroy R. . Journal of Aging Studies 2021, 56, 100906.
  • Wahono NA, Ford D, Wakeling LA, Valentine RA. . Metallomics 2019, 11(3), 613-620.
  • Valentine RA, Wakeling LA, Ferrie LJ, Schartner A, Guilding C, Peterson J. . ARELCS 2019, 16(2), 1-29.
  • Tullo ES, Wakeling LA, Elliott A. . Journal of Intergenerational Relationships 2019, 17(3), 327-339.
  • Aziz SA, Wakeling LA, Miwa S, Alberdi G, Hesketh JE, Ford D. . Molecular Nutrition and Food Research 2017, 61(2), 1600574.
  • Simcock NK, Wakeling LA, Ford D, Wright GA. . PLOS One 2017, 12(4), e0175158.
  • Hardyman J, Tyson J, Jackson K, Aldridge C, Cockell S, Wakeling L, Valentine RA, Ford D. . Metallomics 2016, 8(3), 337-343.
  • Tullo E, Greaves L, Wakeling L. . Educational Gerontology 2016, 42(10), 698-705.
  • Wakeling LA, Ions LJ, Escolme SM, Cockell SJ, Su T, Dey M, Hampton EV, Jenkins G, Wainwright LJ, McKay JA, Ford D. . Human Genomics 2015, 9, 14.
  • Paoli PP, Wakeling LA, Wright GA, Ford D. . AGE 2014, 36, 1239-1247.
  • Ions LJ, Wakeling LA, Bosomworth HJ, Hardyman JEJ, Escolme SM, Swan DC, Valentine RA, Mathers JC, Ford D. . Age 2013, 35(5), 1835-1849.
  • Wakeling LA, Ford D. . Molecular Nutrition & Food Research 2012, 56(12), 1794-1802.
  • Wakeling LA, Ions LJ, Ford D. . Age 2009, 31(4), 327-341.
  • Ions L, Wakeling L, Ford D. . Nutrition Bulletin 2009, 34(3), 303-308.

• Book Chapter

  • McKay JA, Wakeling LA. . In: Deliminda Neves, ed. Anti-Ageing Nutrients Evidence-Based Prevention of Age-Associated Diseases. Wiley-Blackwell Publishing Ltd, 2015, pp.133-147.

• Conference Proceedings (inc. Abstracts)

  • Aziz S, Wakeling L, Hesketh J, Ford D. . In: Experimental Biology Meeting 2014. 2014, San Diego, CA: Federation of American Societies for Experimental Biology.
  • Alberdi G, Wakeling L, Lasa A, Rodriguez VM, Macarulla MT, Ford D, Portillo MP. . In: 20th International Congress of Nutrition. 2013, Granada, Spain: Karger.
  • Escolme SM, Wakeling LA, Alatawi F, Valentine R, Ford D. . In: Nutrition Society Annual Summer Meeting. 2013, 缅北禁地 upon Tyne, UK: Cambridge University Press.
  • Hardyman JEJ, Ogo OA, Tyson J, Wakeling LA, Valentine RA, Ford D. . In: Nutrition Society Annual Summer Meeting. 2013, 缅北禁地 upon Tyne, UK: Cambridge University Press.
  • Wakeling LA, Alatawi F, Ions LJ, Hesketh J, Ford D. . In: Experimental Biology. 2012, San Diego, California, USA: Federation of American Societies for Experimental Biology.
  • Wakeling LA, Alatawi F, Ions LJ, Hesketh J, Ford D. . In: Experimental Biology Meeting. 2012, San Diego, CA: Federation of American Societies for Experimental Biology.
  • Ford D, Ions LJ, Alatawi F, Wakeling LA. . In: Proceedings of the Nutrition Society: A joint meeting of the Nutrition Society and the UK Molecular Epidemiology Group. 2011, London: Cambridge University Press.
  • Wakeling L, Ford D. . In: International Research Conference on Food, Nutrition, and Cancer. 2007, Washington, DC: Journal of Nutrition, American Society for Nutrition.
  • Wakeling LA, McGarr EF, Ford D. . In: Proceedings of the Nutrition Society. 2006, Aberdeen, Scotland: Cambridge University Press.

• Note

  • Wakeling L, Jakubovics N, McHanwell S, Stewart J. . Medical Education 2016, 50(5), 578-579.