缅北禁地

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Staff Profile

Professor Anne Borland

Emerita Professor

  • Telephone: +44 (0) 191 208 4803
  • Address: Biology
    School of Natural and Environmental Sciences
    Ridley Building
    缅北禁地
    缅北禁地 upon Tyne
    NE1 7RU
Background

Introduction

I joined the University as a research associate in 1987 and held a personal NERC fellowship from 1990-1994. I was appointed as Lecturer in Plant Biochemistry in 1998 and was awarded a personal readership in 2003. I held a joint appointment with the Oak Ridge National Laboratory in the US (2012-2018) and was awarded a personal chair in Plant Physiology at 缅北禁地 in 2013.


Qualifications

  • BSc (Hons) Botany, University of Glasgow
  • PhD University College North Wales

Previous Positions

  • NERC Fellow 1990-1994
  • Visiting Lecturer, University Sunderland

External Appointments

  • Joint faculty appointment at the Oak Ridge National Laboratory, TN, USA 
  • Gatsby Plant Science Mentor
  • Subject External Examiner for BSc Plant Biology and MSc Plant Biology and Biotechnology, University College Dublin (2016-2019)
  • External Examiner for BSc Biological Sciences, University of Essex, (2018-2021)
  • Fellow of the Royal Society of Biology
  • Board of Editors Global Change Biology: Bioenergy.

Area of Expertise

Photosynthetic carbon assimilation, crassulacean acid metabolism



Research

Research Interests

My research focusses on a specialised mode of photosynthesis, crassulacean acid metabolism (CAM), which results in substantial (i.e. up to 5 fold) improvement in plant water-use efficiency compared to other modes of photosynthesis (i.e. C3 and C4).  Examples of CAM plants include pineapple, prickly pear cactus, some orchids and Agave (used for production of Tequila).

CAM permits the uptake of CO2 at night and has evolved in up to 7% of higher plants, primarily as an adaptation to water-limited habitats. The expression of CAM is readily modulated by the environment, and thus serves as a model system for establishing the functional significance of genes and enzymes that optimize physiological performance in arid, resource-limited habitats. The day/night separation of carboxylation processes in the photosynthetic cells of CAM plants, also poses fundamental questions in terms of metabolic control and circadian synchronization of metabolism.

The drivers of my research are to understand the molecular and metabolic basis of CAM in its various physiological manifestations and to use this information to exploit the potential of naturally evolved and engineered CAM for sustainable productivity in a warmer and drier world.


Selected recent publications

Ceusters N, Ceusters J, Hurtado-Castano N, Dever LV, Boxall SF, Kneřová, J, Waller JL, Rodick R, Van Den Ende W, Hartwell J, Borland AM. (2021) Phosphorolytic degradation of leaf starch via plastidic α-glucan phosphorylase leads to optimized plant growth and water use efficiency over the diel phases of Crassulacean acid metabolism. Journal of Experimental Botany 72, 4419-4434.            


Ceusters N, Borland AM, Ceusters J. (2021) How to resolve the enigma of diurnal malate remobilisation from the vacuole in plants with crassulacean acid metabolism? New Phytologist 229, 3116-3124.


Liu D, Hu R. Zhang J, Guo H-B, Cheng H, Li L, Borland AM, Qin H, Chen J-G, Muchero W, Tuskan GA, Yang X.(2021) Overexpression of an Agave Phosphoenolpyruvate Carboxylase Improves Plant Growth and Stress Tolerance. Cells 10 (3), 582.


Leverett A, Hurtado Castaño N, Ferguson K, Winter K, Borland AM. (2021) Crassulacean acid metabolism (CAM) supersedes the turgor loss point (TLP) as an important adaptation across a precipitation gradient, in the genus Clusia Functional Plant Biology 48, 703-716.


Abraham PE, Hurtado-Castano N, Cowan-Turner D, Barnes JD, Poudel S, Hettich R, Santelia D, Borland AM (2020) Peeling back the layers of crassulacean acid metabolism: functional differentiation between epidermis and mesophyll of Kalanchoë fedstchenkoi. Plant Journal 103, 869-888


Zhang J, Hu R, Sreedasyam A, Garcia TM, Lipzen A, Wang M, Yerramsetty P, Liu D, Ng V, Schmutz J, Cushman JC, Borland AM, Pasha A, Provart NJ, Chen J-G, Muchero W, Tuskan GA, Yang X. (2020) Light-responsive expression atlas reveals the effects of light quality and intensity in Kalanchoë fedtschenkoi, a plant with crassulacean acid metabolism. GigaScience, 9, art. no. giaa018


Heyduk K, Ray JR, Ayyampalayam S, Moledina N, Borland A, Harding S, Tsai C-J, Leebens Mack J (2019) Nocturnal expression of Crassulacean acid metabolism (CAM) genes predates the origin of CAM in the genus Yucca. Journal of Experimental Botany 70, 6597-6609


Yin H, Weston D, Ranjan P, Abraham P, Jawdy S, Tuskan G, Tschaplinski T, Wullschleger S, Hettich R, Guo H-B, Huo H, Borland A, Wachira J, Gross S, Wang Z, Visel A, Yang X (2018) Diel rewiring and positive selection of ancient plant proteins enabled evolution of CAM photosynthesis in Agave. BMC Genomics 19, 588


Yang X, Hu R, Yin H Borland AM, …. Cushman JC, Schmutz J, Tuskan GA (2017)The Kalanchoë genome provides insights into convergent evolution and building blocks of crassulacean acid metabolism. Nature Communications 8, 1899


, , , , , , , , , , , , , , , ,  (2016) Transcript, protein and metabolite temporal dynamics in the CAM plant Agave. Nature Plants 2, 16178-16185.


Borland AM, Guo H-B, Yang X, Cushman JC (2016). Orchestration of carbohydrate processing for crassulacean acid metabolism. Current Opinion in Plant Biology 31: 118–124.


Borland AM, Hartwell J, Weston DJ, Tschaplinski TJ, Tuskan GA, Yang XH, Cushman JC. (2014) Engineering crassulacean acid metabolism to improve water-use efficiency. Trends in Plant Science 19, 327-338.


Borland AM, Wullschleger SD, Weston DJ, Hartwell J, Tuskan GA, Yang X, Cushman JC. (2014) Climate-resilient agroforestry: physiological responses to climate change and engineering of crassulacean acid metabolism (CAM) as a mitigation strategy. Plant Cell and Environment DOI 10.1111/pce.12479. 


De Pauli HC, Borland AM,  Tuskan GA, Cushman J, Yang X. (2014) Synthetic biology as it relates to CAM photosynthesis: challenges and opportunities. Journal of Experimental Botany 65, 3381-3393.


Barrera-Zambrano VA, Lawson TA, Olmos E, Fernandez-Garcia N, Borland AM. (2014) Leaf anatomical traits which accommodate the facultative engagement of CAM in tropical trees of the genus Clusia. Journal of Experimental Botany 65, 3513-3524. 



 


Teaching

Undergraduate Teaching


Stage 3:

Global challenges for Plant Science Research (BIO3052 Module Leader)


 

 

Publications

  • Articles

    • Leverett A, Hartzell S, Winter K, Garcia M, Aranda J, Virgo A, Smith A, Focht P, Rasmussen-Arda A, Willats WGT, Cowan-Turner D, Borland AM. . Plant Cell and Environment 2023, 46(5), 1472-1488.
    • Fradera-Soler M, Leverett A, Mravec J, Jorgensen B, Borland AM, Grace OM. . Frontiers in Plant Science 2022, 13, 1043429.
    • Liu D, Hu R, Zhang J, Guo H-B, Cheng H, Li L, Borland AM, Qin H, Chen J-G, Muchero W, Tuskan GA, Yang X. . Cells 2021, 10(3), 582.
    • Ceusters N, Borland AM, Ceusters J. . New Phytologist 2021, 229(6), 3116-3124.
    • Abraham PE, Hurtado Castano N, Cowan-Turner D, Barnes J, Poudel S, Hettich R, Flutsch S, Santelia D, Borland AM. . Plant Journal 2020, 103(2), 869-888.
    • Heyduk K, Ray JN, Ayyampalayam S, Moledina N, Borland A, Harding SA, Tsai C-J, Leebens-Mack J. . Journal of Experimental Botany 2019, 70(22), 6597-6609.
    • Yin H, Guo H-B, Weston DJ, Borland AM, Ranjan P, Abraham PE, Jawdy SS, Wachira J, Tuskan GA, Tschaplinski TJ, Wullschleger SD, Guo H, Hettich RL, Gross SM, Wang Z, Visel A, Yang X. Diel rewiring and positive selection of ancient plant proteins enabled evolution of CAM photosynthesis in Agave. BMC Genomics 2018, 19, 588.
    • Power E, Stabler D, Borland AM, Barnes J, Wright GA. . Methods in Ecology and Evolution 2018, 9(3), 734–743.
    • Stabler D, Power E, Borland A, Barnes J, Wright G. . Methods in Ecology and Evolution 2018, 9(2), 430-438.
    • Yang X, Hu R, Yin H, Jenkins J, Shu S, Tang H, Liu D, Weighill DA, Yim WC, Ha J, Heyduk K, Goodstein DM, Guo HB, Moseley RC, Fitzek E, Jawdy S, Zhang Z, Xie M, Hartwell J, Grimwood J, Abraham PE, Mewalal R, Beltran JD, Boxall SF, Dever LV, Palla KJ, Albion R, Garcia T, Mayer J, Lim SD, Wai CM, Peluso P, Buren RV, De Paoli HC, Borland AM, Guo H, Chen JG, Muchero W, Yin Y, Jacobson DA, Tschaplinski TJ, Hettich RL, Ming R, Winter K, Leebens-Mack JH, Smith JAC, Cushman JC, Schmutz J, Tuskan GA. . Nature Communications 2017, 8, 1899.
    • Taybi T, Cushman JC, Borland AM. . Journal of Plant Physiology 2017, 218, 144-154.
    • Abraham PE, Yin H, Borland AM, Weighill D, Lim SD, DePaoli HC, Engle N, Jones PC, Agh R, Weston DJ, Wullschleger SD, Tschaplinski T, Jacobson D, Cushman JC, Hettich RL, Tuskan GA, Yang X. . Nature Plants 2016, 2, 16178.
    • Ceusters J, Borland AM, Taybi T, Frans M, Godts C, De Proft MP. . Journal of Experimental Botany 2014, 65(13), 3705-3714.
    • Zambrano VAB, Lawson T, Olmos E, Fernandez-Garcia N, Borland AM. . Journal of Experimental Botany 2014, 65(13), 3513-3523.
    • Tzortzakis N, Taybi T, Antony E, Singleton I, Borland A, Barnes J. . Postharvest Biology and Technology 2013, 78, 67-75.
    • Wright GA, Baker DD, Palmer MJ, Stabler D, Mustard JA, Power EF, Borland AM, Stevenson PC. . Science 2013, 339(6124), 1202-1204.
    • Haider MS, Barnes JD, Cushman JC, Borland AM. . Journal of Experimental Botany 2012, 63(5), 1985-1996.
    • Tzortzakis N, Taybi T, Roberts R, Singleton I, Borland A, Barnes J. . Postharvest Biology and Technology 2011, 61(2-3), 152-159.
    • Tzortzakis N, Taybi T, Roberts R, Singleton I, Borland A, Barnes J. . Postharvest Biology and Technology 2011, 61(2-3), 152-159.
    • Ceusters J, Borland AM, Godts C, Londers E, Croonenborghs S, Van Goethem D, De Proft MP. . Journal of Experimental Botany 2011, 62(1), 283-291.
    • Ceusters J, Borland AM, Ceusters N, Verdoodt V, Godts C, De Proft MP. . Annals of Botany 2010, 105(2), 301-309.
    • Goumenaki E, Taybi T, Borland A, Barnes J. . Environmental and Experimental Botany 2010, 69(3), 259-266.
    • Ceusters J, Borland AM, De Proft MP. . Plant Signaling and Behavior 2009, 4(3), 212-214.
    • Ceusters J, Borland AM, Londers E, Verdoodt V, Godts C, De Proft MP. . Physiologia Plantarum 2009, 135(2), 174-184.
    • Cushman JC, Agarie S, Albion RL, Elliot SM, Taybi T, Borland AM. . Plant Physiology 2008, 147(1), 228-238.
    • Ceusters J, Borland AM, Londers E, Verdoodt V, Godts C, De Proft MP. . Annals of Botany 2008, 102(3), 389-397.
    • Tzortzakis N, Borland A, Singleton I, Barnes J. . Postharvest Biology and Technology 2007, 45(3), 317-325.
    • Hale ML, Borland AM, Wolff K. . Genome 2005, 48(5), 946-950.
    • Borland AM, Taybi T. . Journal of Experimental Botany 2004, 55(400), 1255-1265.
    • Taybi T, Nimmo HG, Borland AM. . Plant Physiology 2004, 135(1), 587-598.
    • Hale ML, Borland AM, Gustafsson MHG, Wolff K. . Journal of Molecular Evolution 2004, 58(2), 182- 190.
    • Haslam R, Borland A, Maxwell K, Griffiths H. . Journal of Plant Physiology 2003, 160(6), 627-634.
    • Dodd AN, Griffiths H, Taybi T, Cushman JC, Borland AM. . Planta 2003, 216(5), 789-797.
    • Hale ML, Squirrell J, Borland AM, Wolff K. . Molecular Ecology Notes 2002, 2(4), 506-508.
    • Borland AM, Dodd AN. . Functional Plant Biology 2002, 29(6), 707-716.
    • Gehrig HH, Winter K, Cushman J, Borland A, Taybi T. . Plant Molecular Biology Reporter 2000, 18(4), 369-376.
    • Barnes J, Bender J, Lyons T, Borland A. . Journal of Experimental Botany 1999, 50(338), 1423-1435.

  • Book Chapters

    • Antony E, Borland AM. . In: U. Luttge, W. Beyschlag, J. Murata, ed. Progress in Botany. Germany: Springer, 2008, pp.127–143.
    • Niewiadomska E, Borland AM. . In: Luttge, UE; Beyschlag, W; Murata, J, ed. Progress in Botany. Berlin Heidelberg: Springer, 2007, pp.247-266.

  • Conference Proceedings (inc. Abstracts)

    • Borland AM, Griffiths H, Hartwell J, Smith JAC. . In: Journal of Experimental Botany: Workshop on Plant Biomass for Food and Energy. 2009, Baeza, Spain: Oxford University Press.
    • Antony E, Taybi T, Courbot M, Mugford ST, Smith JAC, Borland AM. . In: 14th International Congress of Photosynthesis. 2008, Glasgow, UK: Oxford University Press.
    • Borland A, Elliott S, Patterson S, Taybi T, Cushman J, Pater B, Barnes J. . In: Meeting on Phenotypic Plasticity and the Changing Environment held at the Society for Experimental Biology Plant Frontiers Meeting. 2006, Sheffield: Journal of Experimental Botany, Oxford University Press.
    • Haslam RP, Borland AM, Griffiths H. . In: Functional Plant Biology: 3rd International Congress on Crassulacean Acid Metabolism. 2002, Coconut Beach, Australia: CSIRO Publishing.
    • Griffiths H, Helliker B, Roberts A, Haslam RP, Girnus J, Robe WE, Borland AM, Maxwell K. . In: Functional Plant Biology: 3rd International Congress on Crassulacean Acid Metabolism. 2002, Coconut Beach, Australia: CSIRO Publishing.
    • Taybi T, Cushman JC, Borland AM. . In: 3rd International Congress on Crassulacean Acid Metabolism. 2002, Coconut Beach, Australia: Functional Plant Biology, CSIRO Publishing.

  • Editorials

    • Yang X, Cushman JC, Borland AM, Liu Q. . Frontiers in Plant Science 2020, 11, 394.
    • Yang XH, Cushman JC, Borland AM, Edwards EJ, Wullschleger SD, Tuskan GA, Owen NA, Griffiths H, Smith JAC, De Paoli HC, Weston DJ, Cottingham R, Hartwell J, Davis SC, Silvera K, Ming R, Schlauch K, Abraham P, Stewart JR, Guo HB, Albion R, Ha JM, Lim SD, Wone BWM, Yim WC, Garcia T, Mayer JA, Petereit J, Nair SS, Casey E, Hettich RL, Ceusters J, Ranjan P, Palla KJ, Yin HF, Reyes-Garcia C, Andrade JL, Freschi L, Beltran JD, Dever LV, Boxall SF, Waller J, Davies J, Bupphada P, Kadu N, Winter K, Sage RF, Aguilar CN, Schmutz J, Jenkins J, Holtum JAM. . New Phytologist 2015, 207(3), 491-504.
    • Borland AM, Yang XH. . New Phytologist 2013, 200(4), 946-949.

  • Note

    • Yin H, Guo H-B, Weston DJ, Borland AM, Ranjan P, Abraham PE, Jawdy SS, Wachira J, Tuskan GA, Tschaplinski TJ, Wullschleger SD, Guo H, Hettich RL, Gross SM, Wang Z, Visel A, Yang X. . BMC Genomics 2019, 20(1), 279.

  • Reviews

    • Liu D, Palla KJ, Hu R, Moseley RC, Mendoza C, Chen M, Abraham PE, Labbe JL, Kalluri UC, Tschaplinski TJ, Cushman JC, Borland AM, Tuskan GA, Yang X. . Plant Science 2018, 274, 394-401.
    • Borland AM, Guo HB, Yang X, Cushman JC. . Current Opinion in Plant Biology 2016, 31, 118-124.
    • Cushman JC, Davis SC, Yang XH, Borland AM. . Journal of Experimental Botany 2015, 66(14), 4177-4193.
    • Borland AM, Wullschleger SD, Weston DJ, Hartwell J, Tuskan GA, Yang XH, Cushman JC. . Plant, Cell & Environment 2015, 38(9), 1833-1849.
    • DePaoli HC, Borland AM, Tuskan GA, Cushman JC, Yang XH. . Journal of Experimental Botany 2014, 65(13), 3381-3393.
    • Borland AM, Hartwell J, Weston DJ, Schlauch KA, Tschaplinski TJ, Tuskan GA, Yang XH, Cushman JC. . Trends in Plant Science 2014, 19(5), 327-338.
    • Borland AM, Zambrano VAB, Ceusters J, Shorrock K. . New Phytologist 2011, 191(3), 619-633.
    • Cushman JC, Borland AM. . Plant, Cell and Environment 2002, 25(2), 295-310.
    • Dodd AN, Borland AM, Haslam RP, Griffiths H, Maxwell K. . Journal of Experimental Botany 2002, 53(369), 569-580.