缅北禁地

Sergey is a Principal Investigator and Fellow of the Biosciences Institute at 缅北禁地. Sergey is broadly interested in the phenomenon of evolution, especially in those evolutionary events that are driven primarily by genetic drifts (rather than by natural selection). Currently, Sergey employs structural biology, biochemistry, 3D bioinformatics, and experimental evolution to understand how continuous genetic drifts cause genome degeneration in parasitic forms of life.

Sergey’s life goals include: a weekly lunch appointment with Barak Obama, to be George Church’s “godson” and to create the world’s largest museum of 3D-models of proteins, nucleic acids and other macromolecular entities that comprise a living cell. If interested in the full list, please email sergey.melnikov@ncl.ac.uk.

Read more: www.melnikovlab.com

Research in my lab covers a broad range of topics unified by a single theme: the evolution of protein synthesis. Through structural biology, bioinformatics, biochemistry, and experimental evolution we study protein synthesis machinery in different species to understand how evolution happens in the world that Darwin never saw – the world of proteins and nucleic acids.

Read more: www.melnikovlab.com

Spring:

CMB3000 - Research Project

Fall:

BGM3056 - Evolution and Genomics

• Melnikov S, Kwok H-S, Manakongtreecheep K, Van Den Elzen A, Thoreen CC, Soll D. . Molecular Biology and Evolution 2020, 37(1), 124-133.
• Melnikov SV, Khabibullina NF, Mairhofer E, Vargas-Rodriguez O, Reynolds NM, Micura R, Soll D, Polikanov YS. . Nucleic Acids Research 2019, 47(4), 2089-2100.
• Melnikov SV, van den Elzen A, Stevens DL, Thoreen CC, Soll D. . Proceedings of the National Academy of Sciences of the United States of America 2018, 115(49), E11505-E11512.
• Melnikov SV, Rivera KD, Ostapenko D, Makarenko A, Sanscrainte ND, Becnel JJ, Solomon MJ, Texier C, Pappin DJ, Soll D. . Proceedings of the National Academy of Sciences of the United States of America 2018, 115(27), E6245-E6253.
• Melnikov SV, Manakongtreecheep K, Rivera KD, Makarenko A, Pappin DJ, Soll D. . International Journal of Molecular Sciences 2018, 19(12), 4125.
• Melnikov SV, Soll D, Steitz TA, Polikanov YS. . Nucleic Acids Research 2016, 44(10), 4978-4987.
• Melnikov S, Mailliot J, Rigger L, Neuner S, Shin B-S, Yusupova G, Dever TE, Micura R, Yusupov M. . EMBO Reports 2016, 17(12), 1776-1784.
• Melnikov S, Mailliot J, Shin B-S, Rigger L, Yusupova G, Micura R, Dever TE, Yusupov M. . Journal of Molecular Biology 2016, 428(18), 3570-3576.
• Melnikov S, Manakongtreecheep K, Soll D. . Molecular Biology and Evolution 2018, 35(7), 1588-1598.
• Melnikov S, Ben-Shem A, Yusupova G, Yusupov M. . Nature Communications 2015, 6, 7382.
• Polikanov YS, Melnikov SV, Soll D, Steitz TA. . Nature Structural and Molecular Biology 2015, 22(4), 342-344.