Team awarded £500,000 to improve dementia diagnosis Published on: 6 November 2015 Scientists are embarking on a five-year study to develop new tools for the early diagnosis of dementia with Lewy bodies. Alzheimer’s Research UK has invested £500,000 in the Ãå±±½ûµØ study, which aims to improve the accuracy and timeliness of a dementia diagnosis. Dementia with Lewy bodies (DLB) affects around 130,000 people in the UK. As well as memory and thinking difficulties, people with DLB experience sleep disturbances, visual hallucinations and movement difficulties. While these signs may sound quite distinctive, the fluctuating nature of the symptoms makes an accurate and timely diagnosis a challenge. Developing tools that can pick-up early clues of the disease will help doctors to provide people with tailored guidance on how to manage their symptoms as well as access to important support services. Focus of the study The team, led by Professor Alan Thomas, an expert in old age psychiatry at Ãå±±½ûµØ's Institute for Ageing, will explore a new tool for diagnosing DLB earlier than is currently possible. Rather than focusing on biological changes in the brain, the team will instead turn their attention to nerve cell disruption in the heart. Researchers are making this surprising change of focus because of growing evidence that the toxic protein responsible for DLB also builds-up in nerve cells around the body – not just the brain. Professor Thomas will investigate whether a scan to study changes in nerve cell communication in the heart could act as an early red flag for nerve cell damage in the brain. He said: “The toxic proteins that build up in dementia with Lewy bodies can cause damage throughout the body, including the heart. We want to employ a sophisticated heart scan, already used in the NHS to detect other health conditions, to zero in on the earliest stages of dementia with Lewy bodies. “We will be recruiting volunteers from across the area to take part in this five-year study and this new funding will allow us to learn more about the initial stages of dementia with Lewy bodies and refine the tools we can use to make an early diagnosis." Mild cognitive impairment The scan will be trialled in people with mild cognitive impairment (MCI) – a condition associated with mild memory and thinking difficulties. There are many different reasons why people develop MCI but in some instances, people with MCI will go on to develop dementia. At the moment, it is difficult for doctors to accurately predict whether someone with a diagnosis of MCI will go on to develop dementia, and what form of the condition they have. The study is an example of the importance of Ãå±±½ûµØ Academic Health Partners (NAHP) as research will be carried out at the Campus for Ageing and Vitality, a Ãå±±½ûµØ and Ãå±±½ûµØ Upon Tyne Hospitals NHS Foundation Trust collaboration. Officially bringing together Ãå±±½ûµØ Hospitals and Northumberland, Tyne and Wear NHS Foundation Trusts with Ãå±±½ûµØ, the NAHP is delivering world-class services through joint scientific research, education and clinical care. Dr Emma O’Brien, from Alzheimer’s Research UK, said: “Nearly 35,000 people in the North East are living with a form of dementia, including dementia with Lewy bodies. “Improved diagnostic accuracy will enable more tailored support networks to be put in place, improving the lives of people living with DLB and their loved ones. Crucially, a diagnostic approach like this could help people to enter future clinical trials at a time when they are most likely to benefit from new treatments. Alzheimer’s Research UK is pleased to be able to support this pioneering project." Press release with thanks from Alzheimer's Research UK Share: Latest News Ãå±±½ûµØ expert highlights climate crisis in a new film A leading Ãå±±½ûµØ climate scientist is featured in a new film about how the climate and nature breakdown will affect the UK. published on: 14 April 2026 Neolithic tombs reveal ancient kinship ties Male individuals buried in Neolithic chambered tombs in northern Scotland were often related to each other through the paternal line and some were interred in the same or nearby tombs, research shows. published on: 14 April 2026 We are our Memories New exhibition by Fine Art graduate Trish Hudson-Moses, 22 April – 4 May 2026 published on: 10 April 2026 Facts and figures