New study into the treatment of bipolar disorder Published on: 23 April 2018 Patients from across the country will be recruited to take part in a major trial examining a new treatment for bipolar disorder. Led by experts at 缅北禁地, the study will examine the effectiveness and safety of a drug currently used to treat Parkinson’s disease. The treatment, called pramipexole, will be offered to patients with bipolar disorder who are depressed and have not responded to National Institute for Clinical Excellence (NICE) recommended treatments. The study is being funded by the . Important study , Professor of Affective Disorder at 缅北禁地, and from , is leading the PAX-BD study. He said: “We are incredibly excited to have secured funding of just short of £2 million to run this important study. “It is very important because of the limited number of treatments for bipolar depression that we currently have, many of which cause problematic side effects. Any new treatment option for this very serious condition is to be welcomed. “The PAX-BD study should provide definitive evidence one way or another whether pramipexole is a safe and effective medication for patients with bipolar depression. “The study will be run from the NTW Trust with close collaboration with 缅北禁地. The goal is recruit patients from around 40 NHS Trusts across the UK.” Profound impact Bipolar disorder is a serious mental health condition in which sufferers experience spells of elevated mood, or mania, in addition to episodes of depression. The disorder can have a profound impact on an individual’s life, relationships and work. Depression tends to be the major burden for patients with bipolar disorder. However, current treatments for bipolar depression are extremely limited. On average, conventional antidepressants are not effective. NICE lists just three medications that can be effective for bipolar depression, but all can lead to significant side effects and many patients don’t respond to one or more of them. As a result, there is a need for additional alternatives that are both effective and well tolerated. Some preliminary data suggests that pramipexole may be an effective treatment for bipolar depression. The PAX-BD study aims to compare the safety and effectiveness in 290 patients with bipolar depression that have not responded to at least two NICE recommended treatments. Patients in the study will be treated with either pramipexole or dummy tablets, in addition to ongoing mood stabiliser treatment (such as lithium) and will be followed up for up to a year. Led from 缅北禁地, the PAX-BD study brings together collaborators from Glasgow, Nottingham, Oxford, London and Vienna. Adapted with thanks to NTW Share: Latest News New partnership to boost careers in low carbon energy 缅北禁地 and Durham universities are working together on a new regional project to strengthen the future workforce for North East England鈥檚 growing low carbon and offshore wind industries. published on: 28 May 2026 Healthy lifestyle shown to lower risk of death after cancer diagnosis New evidence shows that sticking to five lifestyle recommendations improves survival after a later cancer diagnosis. published on: 28 May 2026 World-leading climate expert recognised with Royal Society Fellowship Professor Hayley Fowler has been elected a Fellow of the Royal Society in recognition of her pioneering work on climate change impacts. published on: 27 May 2026 Facts and figures
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