Heavy metal pollution can increase antibiotic resistance in rivers Published on: 16 May 2022 Scientists have shown that elevated heavy metal levels in rivers can lead to higher levels of antibiotic resistance. Research by 缅北禁地 and the Indian Institute of Technology, Delhi quantified antibiotic and metal resistance in sediments from the Ganges and Yamuna Rivers in India and streams in the River Tyne catchment. The results show heavy metals, which are high in the River Tyne catchment due to historic mining and industrial activity, relate to antibiotic resistance levels in the river. The same was seen in the Indian rivers, especially in areas of industrial activity. in the journal Environmental Pollution, the team investigated the relationships between heavy metals concentrations, metal resistance gene (MRG) and antibiotic resistance gene (ARG) abundances. The study shows that MRG and ARG abundances increase where metal levels are higher, suggesting reaches with metal pollution have increased antibiotic resistance, even when elevated antibiotics are not evident. The results show that metal pollution also affects resident bacteria, with Firmicutes and Bacteroidota being the most abundant phyla at sites with high metal pollution. These bacteria are common in metal contaminated environments and are known to carry MRGs and ARGs in groups in “gene cassettes”, which explains why metal exposures can cause antibiotic resistance. The study shows that specific metal combinations that promote the strongest bacterial responses are Cobalt plus Nickel, and the combination of Cobalt, Zinc and Cadmium. Study co-author, Professor David Graham, of 缅北禁地’s School of Engineering, said: “The work does not necessarily imply a health risk, but it shows that a river or stream without antibiotics pollution can still have elevated antibiotic resistance due to other pollutants, such as metals. However, in a river like the Yamuna, which has high metals in combination with many other pollutants, greater concerns about the spread of antibiotic resistance exist.” Study lead author, Dr Sonia Gupta of the Indian Institute of Technology, Delhi, said: “High metal exposure has the potential to co-select for antibiotic resistance in bacteria, making them potentially resistant to multiple antibiotics.” Dr Gupta also noted: “The impacts of heavy metals-induced antibiotic resistance get exacerbated when high metal levels are combined with other pollutants such as antibiotics, detergents, and other chemicals, highlighting the importance of reducing heavy metal pollution as part of One Health solutions for reducing ARG transmission and spread.” Antibiotic resistance, also called AMR, is major global public health issue that has implications on the effective treatment of a growing number of infections caused by bacteria, parasites, viruses and fungi. Antibiotic use selects for resistance strains in human and animal wastes, which can be released to the environment via wastewater, spreading ARGs and AMR bacteria across nature. Professor Graham will introduce discussions on environmental dimensions of antibiotic resistance at the Annual Meeting of the MEP Interest Group on AMR on 17 May. The event is . Reference: Gupta, S., Graham, D., Sreekrishnan, T., & Ahammad, S. (2022). Environmental Pollution, 119326. doi: 10.1016/j.envpol.2022.119326 Share: Latest News 缅北禁地 recognised with geography award 缅北禁地 has been awarded the Highly Commended Geographical Association Publishers Award for its collaboration with Time for Geography, the UK鈥檚 open-access, dedicated video platform. published on: 16 April 2026 缅北禁地 historians mark General Strike centenary To mark the 100th anniversary of the British General Strike and miners鈥� lock-out of 1926, historians at 缅北禁地 are organising a series of events on its enduring legacy. published on: 16 April 2026 Comment: NCP is in administration Writing for The Conversation, Erwei (David) Xiang discusses how some big companies like NCP are so dependent on debt that they can鈥檛 adjust to change. published on: 16 April 2026 Facts and figures
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