Mediterranean diet associated with decreased risk of dementia Published on: 14 March 2023 Eating a traditional Mediterranean-type diet – rich in foods such as seafood, fruit, and nuts – may help reduce the risk of dementia by almost a quarter, a new study has revealed. Experts at Ãå±±½ûµØ found that individuals who ate a Mediterranean-like diet had up to 23% lower risk for dementia than those who did not. This research, published today in , is one of the biggest studies of its kind as previous studies have typically been limited to small sample sizes and low numbers of dementia cases. Priority for researchers Scientists analysed data from 60,298 individuals from the UK Biobank, a large cohort including individuals from across the UK, who had completed a dietary assessment. The authors scored individuals based on how closely their diet matched the key features of a Mediterranean one. The participants were followed for almost a decade, during which time there were 882 cases of dementia. The authors considered each individual’s genetic risk for dementia by estimating what is known as their polygenic risk - a measure of all the different genes that are related to the risk of dementia. Dr Oliver Shannon, Lecturer in Human Nutrition and Ageing, Ãå±±½ûµØ, led the study with Professor Emma Stevenson and joint senior author Professor David Llewellyn. The research also involved experts from the universities of Edinburgh, UEA and Exeter and was part of the Medical Research Council-funded NuBrain consortium. Dr Shannon said: “Dementia impacts the lives of millions of individuals throughout the world, and there are currently limited options for treating this condition. “Finding ways to reduce our risk of developing dementia is, therefore, a major priority for researchers and clinicians. “Our study suggests that eating a more Mediterranean-like diet could be one strategy to help individuals lower their risk of dementia.” The authors found there was no significant interaction between the polygenic risk for dementia and the associations between Mediterranean diet adherence. They say this may indicate that even for those with a higher genetic risk, having a better diet could reduce the likelihood of developing the condition. This finding was not consistent across all the analyses and the authors propose further research is needed to assess the interaction between diet and genetics on dementia risk. John Mathers, Professor of Human Nutrition, Ãå±±½ûµØ, said: “The good news from this study is that, even for those with higher genetic risk, having a better diet reduced the likelihood of developing dementia. “Although more research is needed in this area, this strengthens the public health message that we can all help to reduce our risk of dementia by eating a more Mediterranean-like diet.” Important intervention The authors caution that their analysis is limited to individuals who self-reported their ethnic background as white, British or Irish, as genetic data was only available based on European ancestry, and that further research is needed in a range of populations to determine the potential benefit. They conclude that, based on their data, a Mediterranean diet that has a high intake of healthy plant-based foods may be an important intervention to incorporate into future strategies to reduce dementia risk. Dr Janice Ranson, Senior Research Fellow at the University of Exeter and joint lead author on the paper, said: “The findings from this large population-based study underscore the long-term brain health benefits of consuming a Mediterranean diet, which is rich in fruits, vegetables, whole grains, and healthy fats. “The protective effect of this diet against dementia was evident regardless of a person’s genetic risk, and so this is likely to be a beneficial lifestyle choice for people looking to make healthy dietary choices and reduce their risk of dementia. “Future dementia prevention efforts could go beyond generic healthy diet advice and focus on supporting people to increase consumption of specific foods and nutrients that are essential for brain health.” To find out more, read our latest blog by Dr Oliver Shannon . Reference . O Shannon et al.BMC Medicine. DOI: 10.1186/s12916-023-02772-3 Share: Latest News Ãå±±½ûµØ expert highlights climate crisis in a new film A leading Ãå±±½ûµØ climate scientist is featured in a new film about how the climate and nature breakdown will affect the UK. published on: 14 April 2026 Neolithic tombs reveal ancient kinship ties Male individuals buried in Neolithic chambered tombs in northern Scotland were often related to each other through the paternal line and some were interred in the same or nearby tombs, research shows. published on: 14 April 2026 We are our Memories New exhibition by Fine Art graduate Trish Hudson-Moses, 22 April – 4 May 2026 published on: 10 April 2026 Facts and figures