缅北禁地

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Staff Profile

Professor Alison Tyson-Capper

Professor of Molecular Cell Biology, Deputy Dean for Postgraduate Research

Background

Alison Tyson-Capper


Roles and Responsibilities

  • Deputy Dean for Postgraduate Research
  • Faculty Postgraduate Tutor
  • Group Leader and Prinical Investigator 
  • ICM Postgraduate Coordinator (2012-2014) 
  • Supervisor Training Academic Lead

 

University Committee Member

  • University PgR Regulations Committee (Chair)
  • University ePortfolio Management Group (Chair)
  • University Postgraduate Operations Group (Faculty Tutor, Associate Dean)
  • University PgR Subcommittee of UEC (Faculty Tutor, Associate Dean)
  • University Welbeing4all Committee 
  • Graduate School Executive Board
  • Graduate School Committee
  • Faculty Student Representative Committee
  • Faculty Student Programme Development Committee 
  • Chair Postgraduate Committee (ICM)-2015
  • Management Committee (ICM)
  • Institute Executive Committee
  • ICM Athena Swan SAT

External Memberships

  • British Association for Cancer Research
  • European Association for Cancer Research
  • ASBMB (American Society for Biochemistry and Molecular Biology)
  • FASEB (Federation of American Societies for Experimental Biology)
  • British Society for Cell Biology

 

Qualifications:

1994 BSc (Hons) Molecular Biology, School of Life Sciences, University of Liverpool
1999 PhD Molecular Biology, Faculty of Medicine, University of Liverpool

Previous Positions

1/08/2010 - 31/07/2016 Senior Lecturer

01/07/05-31/07/10 Lecturer

1/2/02-30/6/05 Senior Research Associate, University of 缅北禁地, (Wellcome Trust funded)
1/11/98-28/1/02 Research Associate, University of 缅北禁地 (Action Research funded)

Research

As Professor of Molecular Cell Biology, my research group focus on breast cancer research with a particular interest in the regulation and clinical impact of the ERBB2/HER2 gene and how i) splice variants of HER2 are regulated; ii) how they affect signalling pathways/breast cancer biology and iii) their clinical relevance to patients responses to targeted therapies.

We also focus on investigating biological responses to orthopaedic biomaterials and wear debris that can lead to pseudotumors and other adverse reactions. In both these research themes our research investigates these mechanisms at the molecular, cellular and tissue levels.

PhD Supervision

32 Postgraduate students have graduated from my supervision since 2006 (14 PhD students and 18 MRes students). I am happy to consider applications from self-funded students.

Current PhD/MD students:

  • Vic Hart 
  • Shannon Jamieson 
  • Sami Anjum


Teaching

 Recipient of the Vice Chancellor's Distinguished Teacher Award  

 Undergraduate Teaching

  • Personal Tutor
  • UG Project supervisor
  • Assessor (oral presentations and dissertations)

 

Postgraduate Teaching  

  • Deputy Dean for Postgraduate Research, Faculty Postgraduate Tutor
  • Facilitator:Research Student Development Programme
  • ICM Postgraduate Coordinator (2012-2014)
  • PhD and MRes supervisor  
  • PhD examiner and assessor
  • MRes assessor (oral presentations and dissertations)
  • Postgraduate skills Development (early and late stage) 
  • Supervisory Training (FMS & University)
Publications
  • Hart V, Silipo M, Satam S, Gautrey H, Kirby J, Tyson-Capper A. . Journal of Cancer Research and Clinical Oncology 2021, 147, 2893-2912.
  • Jamieson S, Mawdesley A, Deehan D, Kirby J, Holland j, Tyson-Capper A. . Scientific Reports 2021, 11, 10531.
  • Hart V, Gautrey H, John Kirby J, Tyson-Capper A. . Oncotarget 2021, 11(46), 4338-4357.
  • Jamieson S, Anjum S, Kirby J, Tyson-Capper A. . Bioengineering & Biosciences 2021, 4(4).
  • Stanton A, Mowbray C, Lanz M, Brown K, Hilton P, Tyson-Capper A, Pickard RS, Ali ASM, Hall J. . Scientific Reports 2020, 10(1), 8473.
  • Mawdesley A, Davison L, Anjum S, Kirby J, Tyson-Capper A. . Journal of Orthopedic Research and Therapy 2020, 5(1), 1154.
  • Tyson-Capper AJ, Gautrey H. . RNA Biology 2018, 15(12), 1448-1457.
  • Silipo M, Gautrey H, Satam S, Lennard T, Tyson-Capper A. . RNA Biology 2017, 14(5), 536-543.
  • Danilenko M, Dalgliesh C, Pagliarini V, Naro C, Ehrmann I, Feracci M, Kheirollahi-Chadegani M, Tyson-Capper A, Clowry GJ, Fort P, Dominguez C, Sette C, Elliott DJ. . Nucleic Acids Research 2017, 45(7), 4120–4130.
  • Anjum SA, Lawrence H, Holland JP, Kirby JA, Deehan DJ, Tyson-Capper AJ. . Oncotarget 2016, 7(47), 76471-76478.
  • Lawrence H, Deehan DJ, Holland JP, Anjum SA, Mawdesley AE, Kirby JA, Tyson-Capper AJ. . Biochemistry and Biophysics Reports 2016, 7, 374-378.
  • Best A, James K, Hysenaj G, Tyson-Capper A, Elliott DJ. . Frontiers of Chemical Science and Engineering 2016, 10(2), 186-195.
  • Lawrence H, Mawdesley AE, Holland JP, Kirby JA, Deehan DJ, Tyson-Capper AJ. . Oncotarget 2016, 7(7), 7578-7585.
  • Gautrey H, Jackson C, Dittrich A-L, Browell D, Lennard T, Tyson-Capper A. . RNA Biology 2015, 12(10), 1139-1151.
  • Silipo M, Gautrey H, Tyson-Capper A. . Journal of Molecular Cell Biology 2015, 7(5), 388-401.
  • Waring G, Bulmer JN, Robson SC, Tyson-Capper AJ. . PLoS One 2015, 10(5), e0124298.
  • Hong E, Best A, Gautrey H, Chin J, Razdan A, Curk T, Elliott DJ, Tyson-Capper AJ. . BioMed Research International 2015, 395816.
  • Dittrich A, Gautrey H, Browell D, Tyson-Capper A. . Journal of Mammary Gland Biology and Neoplasia 2014.
  • Best A, James K, Dalgliesh C, Hong EA, Kheirolahi-Kouhestani M, Curk T, Xu Y, Danilenko M, Hussain R, Keavney B, Wipat A, Klinck R, Cowell IG, Cheong Lee K, Austin C, Venables JP, Chabot B, Santibanez Koref M, Tyson-Capper AJ, Elliott DJ. . Nature Communications 2014, 5, 4760.
  • Lawrence H, Deehan D, Holland J, Kirby JA, Tyson-Capper AJ. . Bone & Joint Journal 2014, 96-B(9), 1172-1177.
  • Best A, Dalgliesh C, Kheirollahi-Kouhestani M, Danilenko M, Ehrmann I, Tyson-Capper AJ, Elliott DJ. . Biochemical Society Transactions 2014, 42(4), 1152-1158.
  • Eyre R, Harvey I, Stemke-Hale K, Lennard TWJ, Tyson-Capper AJ, Meeson AP. . Tumor Biology 2014.
  • Lawrence H, Deehan DJ, Holland JP, Kirby JA, Tyson-Capper AJ. . Bone and Joint Journal 2014, 96-B(Supp 11), 292-292.
  • Jackson C, Browell D, Gautrey H, Tyson-Capper AJ. . International Journal of Cell Biology 2013, 2013, 973584.
  • Best AJ, Dalgleish C, Ehrmann I, Kheirollahi-Kouhestani M, Tyson-Capper AJ, Elliott DJ. . International Journal of Cell Biology 2013, 2013, 843781.
  • Lal S, Allan A, Markovic D, Walker R, Macartney J, Europe-Finner N, Tyson-Capper A, Grammatopoulos D. . Science Signaling 2013, 6(282), ra53.
  • Gautrey HL, Tyson-Capper AJ. . PLoS One 2012, 7(12), e51497.
  • Tyson-Capper AJ, Lawrence H, Holland JP, Deehan DJ, Kirby JA. . Journal of Orthopaedic Research 2013, 31(11), 1859.
  • Tyson-Capper AJ, Lawrence H, Holland JP, Deehan DJ, Kirby JA. . Annals of the Rheumatic Diseases 2013, 72(3), 460-461.
  • Cork DMW, Robson SC, Venables JP, Tyson-Capper AJ. . In: 60th Annual Meeting of the Society for Gynecologic Investigation. 2013, New York: Sage Publications, Inc.
  • Waring G, Robson SC, Bulmer JN, Tyson-Capper AJ. . In: 60th Annual Meeting of the Society for Gynecologic Investigation. 2013, Orlando, Florida, USA: Sage Publications, Inc.
  • Hong EA, Gautrey HL, Elliott DJ, Tyson-Capper AJ. . Biochemical Society Transactions 2012, 40(4), 826-830.
  • Alfakir A, Dawe N, Eyre R, Tyson-Capper A, Britton K, Robson SC, Meeson AP. . International Journal of Cardiology 2012, 156(2), 133-138.
  • Cork DMW, Lennard TWJ, Tyson-Capper AJ. . Tumor Biology 2012, 33(6), 2329-2340.
  • Sethna F, Tyson-Capper AJ, Shiells EA, Robson SC. . J Steroids Hormon Sci 2011, 2.
  • Hong EEA, Elliot DJ, Tyson-Capper AJ. . In: Reproductive Sciences: 57th Annual Meeting of the Society for Gynecologic Investigation. 2010, Orlando, Florida: Sage Publications, Inc.
  • Tyson-Capper AJ, Zhang Q, Robson SC. . In: Reproductive Sciences: 57th Annual Meeting of the Society for Gynecologic Investigation. 2010, Orlando, Florida: Sage Publications Inc.
  • Kirby JA, Shiells EA, Robson SC, Tyson-Capper AJ. . In: 57th Annual Meeting of the Society for Gynecologic Investigation. 2010, Orlando, Florida: Sage Publications.
  • Tyson-Capper AJ, Shiells EA, Robson SC. . Journal of Molecular Endocrinology 2009, 43(1), 29-41.
  • Smith MC, Tyson-Capper AJ, Robson SC. . In: 55th Annual Meeting of the Society for Gynecologic Investigation. 2008, San Diego, California: Reproductive Sciences: Sage Publications, Inc.
  • Tyson-Capper AJ, Shiells EA, Robson SC. . In: Reproductive Sciences: 55th Annual Meeting of the Society for Gynecologic Investigation. 2008, San Diego, CA, USA: Sage Publications, Inc.
  • Cork DMW, Lennard TWJ, Tyson-Capper AJ. . Breast Cancer Research 2008, 10(3), 207.
  • Tyson-Capper AJ, Robson SC. . In: Reproductive Sciences: 55th Annual Meeting of the Society for Gynecologic Investigation. 2008, San Diego, CA, USA: Sage Publications, Inc.
  • Harper KA, Tyson-Capper AJ. . Biochemical Society Transactions 2008, 36(3), 543-545.
  • Tyson-Capper AJ. . In: BMC Pregnancy and Childbirth: Proceedings of the First and Second European Workshops on Preterm Labour of the Special Non-Invasive Advances in Fetal and Neonatal Evaluation (SAFE) Network of Excellence. 2007, Tarragona, Spain: BioMed Central Ltd.
  • Tyson-Capper AJ, Europe-Finner GN. . Molecular Pharmacology 2006, 69(3), 796-804.
  • Tyson-Capper AJ, Cork DMW, Wesley E, Shiells EA, Loughney AD. . Molecular Human Reproduction 2006, 12(11), 695-701.
  • Tyson-Capper AJ, Cork D, Wesley E, Kokkinos E, Europe-Finner N, Loughney AD. . In: 53rd Annual Scientific Meeting of the Society for Gynecologic Investigation. 2006, Toronto, Canada: Journal of the Society for Gynecologic Investigation: Elsevier.
  • Tyson-Capper AJ, Bailey J, Krainer AR, Robson SC, Europe-Finner GN. . Journal of Biological Chemistry 2005, 280(41), 34521-34529.
  • Bailey J, Tyson-Capper AJ, Gilmore K, Robson SC, Europe-Finner GN. . Journal of Molecular Endocrinology 2005, 34(1), 1-17.
  • Phillips RJ, Tyson-Capper AJ, Bailey J, Robson SC, Europe-Finner GN. . Journal of Clinical Endocrinology and Metabolism 2005, 90(6), 3479-3490.
  • Pollard AJ, Krainer AR, Robson SC, Europe-Finner GN. . Journal of Biological Chemistry 2002, 277(18), 15241-15251.
  • Bailey J, Phillips RJ, Pollard AJ, Gilmore K, Robson SC, Europe-Finner GN. . Journal of Clinical Endocrinology and Metabolism 2002, 87(4), 1717-1728.
  • Pollard AJ, Sparey C, Robson SC, Krainer AR, Europe-Finner GN. . Journal of Clinical Endocrinology and Metabolism 2000, 85(5), 1928-1936.
  • Pollard AJ, Flanagan BF, Newton DJ, Johnson PM. A novel isoform of human membrane cofactor protein (CD46) mRNA generated by intron retention. GENE 1998, 212(1), 39-47.
  • Hong EA, Elliott DJ, Tyson-Capper AJ. . In: 59th Annual Scientific Meeting of the Society for Gynecologic Investigation. 2012, Sage.
  • Miller B, Shelleh A, Kirby JA, Robson SC, Tyson-Capper AJ. . In: 59th Annual Scientific Meeting of the Society for Gynecologic Investigation. 2012, Sage.
  • Cork DMW, Lennard TWJ, Tyson-Capper AJ. . In: 59th Annual Scientific Meeting of the Society for Gynecologic Investigation. 2012, Sage.
  • Waring GJ, Robson SC, Bulmer JN, Tyson-Capper AJ. . In: RCOG World Congress. 2013, Liverpool, UK: Sage Publications.
  • Waring GJ, Robson SC, Bulmer JN, Tyson-Capper AJ. . In: RCOG World Congress. 2013, Liverpool, UK: Wiley-Blackwell Publishing Ltd.
  • Ali ASM, Mowbray C, Lanz M, Stanton A, Bowen S, Varley CL, Hilton P, Brown K, Robson W, Southgate J, Aldridge P, Tyson-Capper A, Abraham S, Pickard RS, Hall J. . Scientific Reports 2017, 7, 11039.
  • Cork DM, Lennard TW, Tyson-Capper AJ. . Tumor Biology 2012, 33(6), 2329-2340.