Staff Profile
Professor Brian Walker
Strategic Advisor, Executive Office
- Email: brian.walker@ncl.ac.uk
- Telephone: +44(0)7973431207
- Personal Website:
Brian Walker joined 缅北禁地 in 2017 as Pro Vice Chancellor for Research Strategy & Resources. He led the design and implementation of the University’s Research Strategy, including the re-alignment of multi-disciplinary research into a portfolio of NUCoREs, the recruitment of additional academics through the NUAcT and NUFutures schemes, the expansion of the University’s innovation centres, and the development of our research culture roadmap and PGR delivery plan.
As Deputy Vice Chancellor from 2022 to 2024, Brian had a broader remit to support the implementation of the University’s Vision & Strategy, responsible for academic leadership of strategy, planning, budgeting and resources across all of our core missions in education and research. He also led on strategic projects that span the portfolios of other members of Executive Board.
As Strategic Advisor in the Executive Office since September 2024, Brian continues to contribute to strategic projects in 缅北禁地 with a particular focus on innovation and translation of research.
He was previously at the University of Edinburgh, where he was Head of the BHF Centre for Cardiovascular Science, Dean of Research for the College of Medicine & Veterinary Medicine, and an architect of the sector-leading Edinburgh Clinical Academic Track scheme. A clinical Endocrinologist, his research on steroid hormones in cardiovascular disease, supported principally by BHF and Wellcome Trust has led to >250 original research papers (h-index >100) and a new drug which has reached clinical trials in patients with dementia. He has also edited three editions of the iconic textbook Davidson’s Principles & Practice of Medicine and supervised >40 PhD students.
Brian is a Fellow of the Royal Society of Edinburgh and of the Academy of Medical Sciences, a former Chair of the Wellcome Trust Clinical Interview Committee, BHF Project Grants Committee, and MRC Population & Systems Medicine Board and was a member of the Clinical Medicine sub-panel for REF2021. Amongst a variety of national and international roles he is currently a BHF Trustee and Board Chair for the National Innovation Centre for Ageing.
See Brian Walker's LinkedIn profile here - https://www.linkedin.com/in/brian-walker-43a80289/
Excessive activity of glucocorticoids (eg cortisol) causes Cushing's syndrome, with hypertension, obesity, glucose intolerance and accelerated cardiovascular disease. Brian Walker’s research using a wide range of translational tools (rodent models, detailed integrative physiology in humans, and epidemiology) has systematically documented that cortisol contributes to the association between multiple risk factors for cardiovascular disease (‘metabolic syndrome’) in the population, how glucocorticoids influence vascular lesions and their complications,and that manipulation of cortisol action offers novel therapeutic approaches in type 2 diabetes and cardiovascular disease.
With BHF support, in epidemiological studies Walker and colleagues showed that plasma cortisol levels are elevated in subjects with metabolic syndrome, in particular those born with low birth weight, and that hypercortisolaemia is an independent prospective cardiovascular risk factor. In parallel pharmaco-epidemiological studies involving >250,000 participants, Walker and colleagues also documented that exposure to exogenous glucocorticoids increases the risk of cardiovascular disease. He then established the CORtisol NETwork (CORNET) consortium, undertaking genome wide association metaanalysis in a sample of >20,000; this provided a genetic instrument with which to establish the causal relationship of hypercortisolaemia with cardiovascular disease; and identified novel biological determinants of tissue-specific cortisol action which his group have since dissected further under a Wellcome Trust Investigator award.
One of the determinants of cortisol action identified by Walker and colleagues has proven to be a tractable therapeutic target. In the mid-1990s the intracellular enzyme 11b-hydroxysteroid dehydrogenase type 1 (11b-HSD1)was thought to inactivate cortisol, and perhaps ‘protect’ liver, adipose tissue, and blood vessels from excessive exposure to cortisol. The Edinburgh group showed, initially in liver, that 11b-HSD1 in fact regenerates active cortisol from cortisone. In a seminal 1995 paper, Walker showed that inhibition of 11b-HSD1 reduces cortisol generation and enhances insulin sensitivity in human liver. His group developed novel stable isotope tracers and other tools to investigate this system comprehensively in vivo in humans, and found that 11b-HSD1 expression is increased selectively within adipose tissue in obesity. Walker also discovered 11b-HSD1 in vascular smooth muscle in the early 1990s and later showed that glucocorticoids generated within the vessel wall inhibit angiogenesis. By deleting 11b-HSD1 new vessel growth is enhanced, eg following myocardial infarction in mice. This offers the exciting prospect of 11b-HSD1 inhibitors enhancing revascularisation following ischaemia. These findings spawned intensive efforts in the pharmaceutical industry to make 11b-HSD1 inhibitors (>200 new chemical entity patents filed). Supported by a Wellcome Trust Seeding Drug Discovery award, Walker and colleagues discovered novel 11b-HSD1 inhibitors, developed these to clinical trials and in commercial partnership are exemplifying their efficacy in metabolic, cardiovascular and also cognitive disease.
Another mechanism dictating tissue-specific responsiveness to glucocorticoids is the local expression of ABC transporters. Walker's group showed that ABCC1 is expressed in the absence of ABCB1 in adipose tissue, resulting in excretion of corticosterone but not cortisol from adipose tissue. They have pursued the therapeutic implication of this result, that corticosterone might be as effective as cortisol (hydrocortisone) in steroid replacement therapy without inducing side effects mediated in adipose tissue, such as obesity.
Walker's group have applied their unique tools and expertise to explain alterations in steroid metabolism and action in clinical settings from sepsis to heart failure, and to dissect the cardiometabolic consequences of manipulating additional components of steroid signalling, including 5a-reductases (in prostate disease) and aromatase (in breast disease). Already, this work has identified steroids with selective anti-inflammatory rather than dysmetabolic properties, and novel tissue-specific determinants of intracellular steroid concentrations, that have important therapeutic potential.
Brian Walker is best known in undergraduate medical education for his contribution to Davidson's Principles & Practice of Medicine, an iconic textbook that is read by >250 thousand students per edition, to which Brian contributed as an Endocrinology chapter author for 5 editions and editor for 3 editions. His role as editor led to discussions of curriculum and pedagogy with many international educators, including during tours in India and Russia.
In postgraduate education, Brian has led the development of an online MSc in Translational Medicine and was one of the team at Edinburgh who delivered a 4y PhD programme in Cardiovascular Science with serial awards from Wellcome and BHF. He has supervised more than 40 PhD students, of whom around half are clinicians and around two thirds were subsequently employed in research-active roles. In addition, Brian was an architect of the acclaimed Edinburgh Clinical Academic Track (ECAT) scheme, funded serially by Wellcome, which supports clinicians from pre-PhD through to Lectureship and Career Development Fellowship level. ECAT was the model for similar schemes in Wales (WCAT) and Ireland (ICAT).
-
Articles
- Boyle LD, Miguelez-Crespo A, Paul M, Villalobos E, Toews J, Ivatt L, Nagy B, Magennis M, Homer NZM, Andrew A, Viau V, Hammond G, Stimson RH, Walker BR, Nixon M. . Nature Communications 2025, 16, 545.
- Homer NZM, Nicol M, Madhra M, Naredo-Gonzalez G, Laforest S, Slayden OD, Hillier SG, Walker BR, Warner P, Andrew R, Critchley HOD. . Endocrine Connections 2025, 14(5), e240638.
- Malbon AJ, Czopek A, Beekman AM, Goddard ZR, Boyle A, Ivy JR, Stewart K, Walker BR, Dhaun N, Bailey MA, Morgan RA. . Bioscience Reports 2025, 45(2), BSR20241636.
- Kyle CJ, Boyle LD, Nixon M, Homer NZ, Ramage LE, Kelman A, Freel M, Andrew R, Walker BR, Stimson RH. . European Journal of Endocrinology 2024, 191(6), 535-544.
- Devine K, Russell CD, Blanco GR, Walker BR, Homer NZM, Denham SG, Simpson JP, Leavy OC, Elneima O, McAuley HJC, Shikotra A, Singapuri A, Sereno M, Saunders RM, Harris VC, Houchen-Wolloff L, Greening NJ, Lone NI, Thorpe M, Greenhalf W, Chalmers JD, Ho LP, Horsley A, Marks M, Raman B, Moore SC, Dunning J, Semple MG, Andrew R, Wain LV, Evans RA, Brightling CE, Baillie JK, Reynolds RM. . Clinical Endocrinology 2024, 100(4), 317-327.
- Villalobos E, Miguelez-Crespo A, Morgan RA, Ivatt L, Kurian D, Aguilar J, Kline RA, Wishart TM, Morton NM, Stimson RH, Andrew R, Walker BR, Nixon M. . Journal of Endocrinology 2024, 262(2), e240024.
- Livingstone DEW, Sooy K, Sykes C, Webster SP, Walker BR, Andrew R. . British Journal of Pharmacology 2024, 181(8), 1256-1267.
- Bankier S, Wang L, Crawford A, Morgan RA, Ruusalepp A, Andrew R, Bjorkegren JLM, Walker BR, Michoel T. . Frontiers Endocrinology 2023, 14, 1186252.
- Brossaud J, Bosch-Bouju C, Marissal-Arvy N, Campas-Lebecque M-N, Helbling J-C, Webster SP, Walker BR, Fioramonti X, Ferreira G, Barat P, Corcuff J-B, Moisan M-P. . Diabetologia 2023, 66, 1735-1747.
- Kleeman SO, Demestichas B, Mourakis N, Loiero D, Ferrer M, Bankier S, Yosef JRA, Lee H, Chantzichristos D, Regan C, Preall J, Sinha S, Rosin N, Yipp B, de Almeida LGN, Biernaskie J, Dufour A, Tober-Lau P, Ruusalepp A, Bjorkegren JLM, Ralser M, Kurth F, Demechev V, Heywood T, Qing G, Johannsson G, Koelzer VH, Walker BR, Meyer HV, Janowitz T. . Cell Genomics 2023, 3(8), 100347.
- Khan S, Livingstone DEW, Zielinska A, Doig C, Cobice DF, Esteves C, Man J, Homer NZM, Seckl JR, MacKay CL, Webster SP, Lavery GG, Chapman KE, Walker BR, Andrew R. . Journal of Endocrinology 2023, 258(3), e230034.
- Davidson CT, Miller E, Muir M, Dawson JC, Lee M, Aitken S, Serrels A, Webster SP, Homer NZM, Andrew R, Brunton VG, Hadoke PWF, Walker BR. . PLoS ONE 2023, 18(3), e0255709.
- Naredo-Gonzalez G, Upret R, Jansen MA, Semple S, Sutcliffe OB, Marshall I, Walker BR, Andrew R. . Scientific Reports 2022, 12, 16268.
- Duncan PJ, McClafferty H, Nolan O, Ding Q, Homer NZM, Le Tissier P, Walker BR, Shipston MJ, Romanò N, Chambers TJG. . Journal of Neuroendocrinology 2022, 34(7), e13165.
- Abernethie AJ, Gastaldello A, Maltese G, Morgan RA, McInnes KJ, Small GR, Walker BR, Livingstone DEW, Hadoke PWF, Andrew R. . European Journal of Pharmacology 2022, 929, 175111.
- Kyle CJ, Nixon M, Homer NZ, Morgan RA, Andrew R, Stimson RH, Walker BR. . Metabolism 2022, 128, 155118.
- Bankier S, Crawford A, Altmaier E, Barnes C, Clark D, Ermel R, Friedrich N, van der Harst P, Joshi P, Karhunen V, Lahti J, Mahajan A, Mangino M, Nethander M, Neumann A, Pietzner M, Sukhavasi K, Wang C, Bakker S, Bjorkegren J, Campbell H, Eriksson J, Gieger C, Hayward C, Jarvelin M-R, McLachlan S, Morris A, Ohlsson C, Pennell C, Price J, Rudan I, Ruusalepp A, Spector T, Tiemeier H, Volzke H, Wilson J, Michoel T, Timpson N, Smith GD, Walker B. . Journal of Human Genetics 2021, 66, 625-636.
- Warner P, Whitaker LHR, Parker RA, Weir CJ, Douglas A, Hansen CH, Madhra M, Hillier SG, Saunders PTK, Iredale JP, Semple S, Slayden OD, Walker BR, Critchley HOD. . EBioMedicine 2021, 69, 103434.
- Chantzichristos D, Svensson P-A, Garner T, Glad CA, Walker BR, Bergthorsdottir R, Ragnarsson O, Trimpou P, Stimson RH, Borresen SW, Feldt-Rasmussen U, Jansson P-A, Skrtic S, Stevens A, Johannsson G. . eLife 2021, 10, e62236.
- Dlamini SN, Lombard Z, Micklesfield LK, Crowther N, Norris SA, Snyman T, Crawford AA, Walker BR, Goedecke JH. . Endocrine Connections 2021, 10(8), 873–884.
- Anderson AJ, Andrew R, Homer NZM, Hughes KA, Boyle LD, Nixon M, Karpe F, Stimson RH, Walker BR. . Journal of Clinical Endocrinology & Metabolism 2021, 106(3), e1206-e1220.
- Bell RMB, Villalobos E, Nixon M, Miguelez-Crespo A, Murphy L, Fawkes A, Coutts A, Sharp MGF, Koerner MV, Allan E, Meijer OC, Houtman R, Odermat A, Beck KR, Denham SG, Lee P, Homer NZM, Walker BR, Morgan RA. . Molecular Metabolism 2021, 48, 101225.
- van Keulen BJ, Dolan CV, van der Voorn B, Andrew R, Walker BR, Hulshoff Poll H, Boomsma DI, Rotteveel J, Finken MJJ. . Endocrine Connections 2020, 9(6), 542-551.
- van Keulen BJ, Dolan CV, Andrew R, Walker BR, Hulshoff Pol HE, Boomsma DI, Rotteveel J, Finken MJJ. . Twin Research and Human Genetics 2020, 23(1), 33-38.
- Melvin A, Chantzichristos D, Kyle CJ, Mackenzie SD, Walker BR, Johannsson G, Stimson RH, O'Rahilly S. . The Journal of Clinical Endocrinology and Metabolism 2020, 105(5).
- van Keulen BJ, Dolan CV, Andrew R, Walker BR, Hulshoff Pol HE, Boomsma DI, Rotteveel J, Finken MJJ. . Nutrients 2020, 12(5), 1525.
- Laforest S, Pelletier M, Denver N, Poirier B, Nguyen S, Walker BR, Durocher F, Homer NZM, Diorio C, Andrew R, Tchernof A. . The Journal of Clinical Endocrinology and Metabolism 2020, 105(4), 1-13.
- Stomby A, Otten J, Ryberg M, Andrew R, Walker BR, Olsson T. . European Journal of Endocrinology 2020, 182(4), 447-457.
- Laforest S, Pelletier M, Denver N, Poirier B, Nguyen S, Walker BR, Durocher F, Homer NZM, Diorio C, Tchernof A, Andrew R. . Journal of Steroid Biochemistry and Molecular Biology 2019, 195.
- Mak TCS, Livingstone DEW, Nixon M, Walker BR, Andrew R. . Endocrinology 2019, 160(9), 2061–2073.
- Hill LA, Vassiliadi DA, Dimopoulos I, Anderson AJ, Boyle LD, Kilgour AHM, Stimson RH, Machado Y, Overall CM, Walker BR, Lewis JG, Hammond GL. . Journal of Endocrinology 2019, 240(1), 27-39.
- Crawford AA, Söderberg S, Kirschbaum C, Murphy L, Eliasson M, Ebrahim S, Smith GD, Olsson T, Sattar N, Lawlor DA, Timpson NJ, Reynolds RM, Walker BR. . European Journal of Endocrinology 2019, 181(4), 429-438.
- Wei L, Lai ECC, Kao-Yang Y-H, Walker BR, MacDonald TM, Andrew R. . BMJ 2019, 365, 1204.
- Gibb FW, Dixon JM, Clarke C, Homer NZ, Faqehi AMM, Andrew R, Walker BR. . Journal of Clinical Endocrinology & Metabolism 2019, 104(9), 3670-3678.
- van Keulen BR, Dolan CV, Andrew R, Walker BR, HulshoffPol HE, Boomsma DI, Rotteveel J, Finken MJJ. . The Journal of Clinical Endocrinology & Metabolism 2019, 105(2), 443-452.
- Spaanderman DCE, Nixon M, Buurstede JC, Sips HHCM, Schilperoort M, Kuipers EN, Backer EA, Kooijman S, Rensen PCN, Homer NZM, Walker BR, Meijer OC, Kroon J. . Journal of Endocrinology 2019, 240(1), 51-63.
- Hawcutt DB, Francis B, Carr DF, Jorgensen AL, Yin P, Wallin N, O'Hara N, Zhang EJ, Bloch KM, Ganguli A, Thompson B, McEvoy L, Peak M, Crawford AA, Walker BR, Blair JC, Couriel J, Smyth R, Pirmohamed M. . Lancet Respiratory Medicine 2018, 6(6), 442-450.
- Hawcutt DB, Francis B, Carr DF, Jorgensen AL, Yin P, Wallin N, O'Hara N, Zhang EJ, Bloch KM, Ganguli A, Thompson B, McEvoy L, Peak M, Crawford AA, Walker BR, Blair JC, Couriel J, Smyth RL, Pirmohamed M. . The Lancet Respiratory Medicine 2018, 6(6), 442-450.
- Weir G, Ramage LE, Akyol N, Rhodes JK, Kyle CJ, Fletcher AM, Craven TH, Wakelin SJ, Drake AJ, Gregoriades M-L, Ashton C, Weir N, van Beek EJR, Karpe F, Walker BR, Stimson RH. . Cell Metabolism 2018, 27(6), 1348-1355.e4.
- Morgan R, Keen J, Halligan D, O'Callaghan A, Andrew R, Livingstone D, Abernethie A, Maltese G, Walker B, Hadoke P. . PLoS ONE 2018, 13(2), e0192746.
- Cobice DF, Livingstone DEW, McBride A, MacKay CL, Walker BR, Webster SP, Andrew R. . Biochemical Pharmacology 2018, 148, 88-99.
- Morgan RA, Keen JA, Homer N, Nixon M, McKinnon-Garvin A, Moses-Williams J, Davis D, Hadoke PWF, Walker BR. . Endocrinology 2018, 159(11), 3791-3800.
- Tachmazidou I, Suveges D, Min JL, Ritchie GRS, Steinberg J, Walter K, Iotchkova V, Schwartzentruber J, Huang J, Memari Y, McCarthy S, Crawford AA, Bombieri C, Cocca M, Farmaki A-E, Gaunt TR, Jousilahti P, Kooijman MN, Lehne B, Malerba G, Mannisto S, Matchan A, Medina-Gomez C, Metrustry SJ, Nag A, Ntalla I, Paternoster L, Rayner NW, Sala C, Scott WR, Shihab HA, Southam L, St Pourcain B, Traglia M, Trajanoska K, Zaza G, Zhang W, Artigas MS, Bansal N, Benn M, Chen Z, Danecek P, Lin W-Y, Locke A, Luan J, Manning AK, Mulas A, Sidore C, Tybjaerg-Hansen A, Varbo A, Zoledziewska M, Finan C, Hatzikotoulas K, Hendricks AE, Kemp JP, Moayyeri A, Panoutsopoulou K, Szpak M, Wilson SG, Boehnke M, Cucca F, Di Angelantonio E, Langenberg C, Lindgren C, McCarthy MI, Morris AP, Nordestgaard BG, Scott RA, Tobin MD, Wareham NJ, Burton P, Chambers JC, Smith GD, Dedoussis G, Felix JF, Franco OH, Gambaro G, Gasparini P, Hammond CJ, Hofman A, Jaddoe VWV, Kleber M, Kooner JS, Perola M, Relton C, Ring SM, Rivadeneira F, Salomaa V, Spector TD, Stegle O, Toniolo D, Uitterlinden AG, Barroso I, Greenwood CMT, Perry JRB, Walker BR, Butterworth AS, Xue Y, Durbin R, Small KS, Soranzo N, Timpson NJ, Zeggini E. . American Journal of Human Genetics 2017, 100(6), 865-884.
- Neumann A, Direk N, Crawford AA, Mirza S, Adams H, Bolton J, Hayward C, Strachan DP, Payne EK, Smith JA, Milaneschi Y, Penninx B, Hottenga JJ, de Geus E, Oldehinkel AJ, van der Most PJ, de Rijke Y, Walker BR, Tiemeier H. . Psychoneuroendocrinology 2017, 85, 88-95.
- Webster SP, McBride A, Binnie M, Sooy K, Seckl JR, Andrew R, Pallin TD, Hunt HJ, Perrior TR, Ruffles VS, Ketelbey JW, Boyd A, Walker BR. . British Journal of Pharmacology 2017, 174(5), 396-408.
- Gastaldello A, Livingstone DEW, Abernethie AJ, Tsang N, Walker BR, Hadoke PWF, Andrew R. . Biochemical Pharmacology 2017, 129, 73-84.
- Livingstone DEW, Di Rollo EM, Mak TC-S, Sooy K, Walker BR, Andrew R. . Journal of Endocrinology 2017, 232(1), 29-36.
- Homer N, Kothiya S, Rutter A, Walker BR, Andrew R. . Analytical Biochemistry 2017, 538, 34-37.
- Morgan RA, Beck KR, Nixon M, Homer NZM, Crawford AA, Melchers D, Houtman R, Meijer OC, Stomby A, Anderson AJ, Upreti R, Stimson RH, Olsson T, Michoel T, Cohain A, Ruusalepp A, Schadt EE, Bjorkegren JLM, Andrew R, Kenyon CJ, Hadoke PWF, Odermatt A, Keen JA, Walker BR. . Scientific Reports 2017, 7, 10633.
- Stimson RH, Anderson AJ, Ramage LE, Macfarlane DP, de Beaux AC, Mole DJ, Andrew R, Walker BR. . Diabetes, Obesity and Metabolism 2017, 19(6), 883-891.
- Alwashih MA, Stimson RH, Andrew R, Walker BR, Watson DG. . Scientific Reports 2017, 7(1), 11488.
- Mylonas KJ, Turner NA, Bageghni SA, Kenyon CJ, White CI, McGregor K, Kimmitt RA, Sulston R, Kelly V, Walker BR, Porter KE, Chapman KE, Gray GA. . Journal of Endocrinology 2017, 233(3), 315-327.
- Morgan RA, Keen JA, Walker BR, Hadoke PWF. . PLoS ONE 2016, 11(9), e0163815.
- Nakamura Y, Walker BR, Ikuta T. . Stress 2016, 19(2), 151-157.
- Cobice DF, Livingstone DEW, MacKay CL, Goodwin RJA, Smith LB, Walker BR, Andrew R. . Analytical Chemistry 2016, 88(21), 10362-10367.
- Anderson AJ, Andrew R, Homer NZ, Jones GC, Smith K, Livingstone DE, Walker BR, Stimson RH. . Journal of Clinical Endocrinology and Metabolism 2016, 101(10), 3787-3793.
- Ramage LE, Akyol M, Fletcher AM, Forsythe J, Nixon M, Carter RN, van Beek EJR, Morton NM, Walker BR, Stimson RH. . Cell Metabolism 2016, 24(1), 130-141.
- Horikoshi M, Beaumont RN, Day FR, Warrington NM, Kooijman MN, Fernandez-Tajes J, Feenstra B, Van Zuydam NR, Gaulton KJ, Grarup N, Bradfield JP, Strachan DP, Li-Gao R, Ahluwalia TS, Kreiner E, Rueedi R, Lyytikainen L-P, Cousminer DL, Wu Y, Thiering E, Wang CA, Have CT, Hottenga J-J, Vilor-Tejedor N, Joshi PK, Boh ETH, Ntalla I, Pitkanen N, Mahajan A, Van Leeuwen EM, Joro R, Lagou V, Nodzenski M, Diver LA, Zondervan KT, Bustamante M, Marques-Vidal P, Mercader JM, Bennett AJ, Rahmioglu N, Nyholt DR, Ma RCW, Tam CHT, Tam WH, Ganesh SK, Van Rooij FJA, Jones SE, Loh P-R, Ruth KS, Tuke MA, Tyrrell J, Wood AR, Yaghootkar H, Scholtens DM, Paternoster L, Prokopenko I, Kovacs P, Atalay M, Willems SM, Panoutsopoulou K, Wang X, Carstensen L, Geller F, Schraut KE, Murcia M, Van Beijsterveldt CEM, Willemsen G, Appel EVR, Fonvig CE, Trier C, Tiesler CMT, Standl M, Kutalik Z, Bonas-Guarch S, Hougaard DM, Sanchez F, Torrents D, Waage J, Hollegaard MV, De Haan HG, Rosendaal FR, Medina-Gomez C, Ring SM, Hemani G, McMahon G, Robertson NR, Groves CJ, Langenberg C, Luan J, Scott RA, Zhao JH, Mentch FD, MacKenzie SM, Reynolds RM, Lowe WL, Tonjes A, Stumvoll M, Lindi V, Lakka TA, Van Duijn CM, Kiess W, Korner A, Sorensen TIA, Niinikoski H, Pahkala K, Raitakari OT, Zeggini E, Dedoussis GV, Teo Y-Y, Saw S-M, Melbye M, Campbell H, Wilson JF, Vrijheid M, De Geus EJCN, Boomsma DI, Kadarmideen HN, Holm J-C, Hansen T, Sebert S, Hattersley AT, Beilin LJ, Newnham JP, Pennell CE, Heinrich J, Adair LS, Borja JB, Mohlke KL, Eriksson JG, Widen E, Kahonen M, Viikari JS, Lehtimaki T, Vollenweider P, Bonnelykke K, Bisgaard H, Mook-Kanamori DO, Hofman A, Rivadeneira F, Uitterlinden AG, Pisinger C, Pedersen O, Power C, Hypponen E, Wareham NJ, Hakonarson H, Davies E, Walker BR, Jaddoe VWV, Jarvelin M-R, Grant SFA, Vaag AA, Lawlor DA, Frayling TM, Smith GD, Morris AP, Ong KK, Felix JF, Timpson NJ, Perry JRB, Evans DM, McCarthy MI, Freathy RM. . Nature 2016, 538(7624), 248-252.
- Morton NM, Beltram J, Carter RN, Michailidou Z, Gorjanc G, McFadden C, Barrios-Llerena ME, Rodriguez-Cuenca S, Gibbins MTG, Aird RE, Moreno-Navarrete JM, Munger SC, Svenson KL, Gastaldello A, Ramage L, Naredo G, Zeyda M, Wang ZV, Howie AF, Saari A, Sipila P, Stulnig TM, Gudnason V, Kenyon CJ, Seckl JR, Walker BR, Webster SP, Dunbar DR, Churchill GA, Vidal-Puig A, Fernandez-Real JM, Emilsson V, Horvat S. . Nature Medicine 2016, 22(7), 771-779.
- Faqehi AMM, Cobice DF, Naredo G, Mak TCS, Upreti R, Gibb FW, Beckett GJ, Walker BR, Homer NZM, Andrew R. . Talanta 2016, 151, 148-156.
- Stirrat LI, O'Reilly JR, Barr SM, Andrew R, Riley SC, Howie AF, Bowman M, Smith R, Lewis JG, Denison FC, Forbes S, Seckl JR, Walker BR, Norman JE, Reynolds RM. . Psychoneuroendocrinology 2016, 63, 135-143.
- White CI, Jansen MA, McGregor K, Mylonas KJ, Richardson RV, Thomson A, Moran CM, Seckl JR, Walker BR, Chapman KE, Gray GA. . Endocrinology 2016, 157(1), 346-357.
- Gibb F, Homer NZM, Faqehi AMM, Upreti R, Livingstone DE, McInnes KJ, Andrew R, Walker BR. . Journal of Clinical Endocrinology and Metabolism 2016, 101(5), 2040-2046.
- Gibb FW, Stewart A, Walker BR, Strachan MWJ. . Clinical Endocrinology 2016, 85(6), 831-835.
- Nixon M, Mackenzie SD, Taylor AI, Homer NZM, Livingstone DE, Mouras R, Morgan RA, Mole DJ, Stimson RH, Reynolds RM, Elfick APD, Andrew R, Walker BR. . Science Translational Medicine 2016, 8(352), 352ra109.
- Coutinho AE, Kipari TMJ, Zhang Z, Esteves CL, Lucas CD, Gilmour JS, Webster SP, Walker BR, Hughes J, Savill JS, Seckl JR, Rossi AG, Chapman KE. . Endocrinology 2016, 157(7), 2928-2936.
- Upreti R, Naredo G, Faqehi AMM, Hughes KA, Stewart LH, Walker BR, Homer NZM, Andrew R. . Talanta 2015, 131, 728-735.
- Wheelan N, Webster SP, Kenyon CJ, Caughey S, Walker BR, Holmes MC, Seckl JR, Yau JLW. . Neuropharmacology 2015, 91, 71-76.
- Warner P, Weir CJ, Hansen CH, Douglas A, Madhra M, Hillier SG, Saunders PTK, Iredale JP, Semple S, Walker BR, Critchley HOD. . BMJ Open 2015, 5(1), e006837.
- Yau JLW, Wheelan N, Noble J, Walker BR, Webster SP, Kenyon CJ, Ludwig M, Seckl JR. . Neurobiology of Aging 2015, 36(1), 334-343.
- Mohd-Shukri NA, Duncan A, Denison FC, Forbes S, Walker BR, Norman JE, Reynolds RM. . Nutrients 2015, 7(10), 8431-8443.
- Goedecke JH, Chorell E, Livingstone D, Stimson RH, Hayes P, Adams K, Dave JA, Victor H, Levitt NS, Kahn SE, Seckl JR, Walker BR, Olsson T. . International Journal of Obesity 2015, 39(2), 303-311.
- Kirkby NS, Low L, Wu J, Miller E, Seckl JR, Walker BR, Webb DJ, Hadoke PWF. . Journal of Visualized Experiments 2015, 2015(99), e50627.
- Dakin RS, Walker BR, Seckl JR, Hadoke PWF, Drake AJ. . International Journal of Obesity 2015, 39(10), 1539-1547.
- Chiswick CA, Reynolds RM, Denison FC, Whyte SA, Drake AJ, Newby DE, Walker BR, Forbes S, Murray GD, Quenby S, Wray S, Norman JE. . BMJ Open 2015, 5(1), e006854.
- Chiswick C, Reynolds RM, Denison F, Drake AJ, Forbes S, Newby DE, Walker BR, Quenby S, Wray S, Weeks A, Lashen H, Rodriguez A, Murray G, Whyte S, Norman JE. . The Lancet Diabetes and Endocrinology 2015, 3(10), 778-786.
- Stomby A, Simonyte K, Mellberg C, Ryberg M, Stimson RH, Larsson C, Lindahl B, Andrew R, Walker BR, Olsson T. . International Journal of Obesity 2015, 39(5), 814-819.
- Forbes S, Barr SM, Reynolds RM, Semple S, Gray C, Andrew R, Denison FC, Walker BR, Norman JE. . Diabetologia 2015, 58(11), 2615-2626.
- Sooy K, Noble J, McBride A, Binnie M, Yau JLW, Seckl JR, Walker BR, Webster SP. . Endocrinology 2015, 156(12), 4592-4603.
- Livingstone DEW, Barat P, Di Rollo EM, Rees GA, Weldin BA, Rog-Zielinska EA, Macfarlane DP, Walker BR, Andrew R. . Diabetes 2015, 64(2), 447-458.
- Kilgour AHM, Semple S, Marshall I, Andrews P, Andrew R, Walker BR. . Journal of Clinical Endocrinology and Metabolism 2015, 100(2), 483-489.
- Liu X, Turban S, Carter RN, Ahmad S, Ramage L, Webster SP, Walker BR, Seckl JR, Morton NM. . Frontiers in Endocrinology 2014, 5, 165.
- Chau Y-Y, Bandiera R, Serrels A, Martinez-Estrada OM, Qing W, Lee M, Slight J, Thornburn A, Berry R, Mchaffie S, Stimson RH, Walker BR, Chapuli RM, Schedl A, Hastie N. . Nature Cell Biology 2014, 16(4), 367-375.
- Manzanares N, Monseny R, Ortega L, Montalvo I, Franch J, Gutierrez-Zotes A, Reynolds RM, Walker BR, Vilella E, Labad J. . Psychoneuroendocrinology 2014, 39(1), 1-10.
- Gambineri A, Fanelli F, Tomassoni F, Munarini A, Pagotto U, Andrew R, Walker BR, Pasquali R. . European Journal of Endocrinology 2014, 171(1), 47-57.
- Stimson RH, Mohd-Shukri NA, Bolton JL, Andrew R, Reynolds RM, Walker BR. . Journal of Clinical Endocrinology and Metabolism 2014, 99(1), 160-168.
- Livingstone DEW, Di Rollo EM, Yang C, Codrington LE, Mathews JA, Kara M, Hughes KA, Kenyon CJ, Walker BR, Andrew R. . Journal of Endocrinology 2014, 222(2), 257-266.
- Han TS, Conway GS, Willis DS, Krone N, Rees DA, Stimson RH, Arlt W, Walker BR, Ross RJ. . Journal of Clinical Endocrinology and Metabolism 2014, 99(8), E1547–E1555.
- Sarabdjitsingh RA, Zhou M, Yau JLW, Webster SP, Walker BR, Seckl JR, Joels M, Krugers HJ. . Neuropharmacology 2014, 81, 231-236.
- Bolton JL, Hayward C, Direk N, Lewis JG, Hammond GL, Hill LA, Anderson A, Huffman J, Wilson JF, Campbell H, Rudan I, Wright A, Hastie N, Wild SH, Velders FP, Hofman A, Uitterlinden AG, Lahti J, Raikkonen K, Kajantie E, Widen E, Palotie A, Eriksson JG, Kaakinen M, Jarvelin M-R, Timpson NJ, Davey Smith G, Ring SM, Evans DM, St Pourcain B, Tanaka T, Milaneschi Y, Bandinelli S, Ferrucci L, van der Harst P, Rosmalen JGM, Bakker SJL, Verweij N, Dullaart RPF, Mahajan A, Lindgren CM, Morris A, Lind L, Ingelsson E, Anderson LN, Pennell CE, Lye SJ, Matthews SG, Eriksson J, Mellstrom D, Ohlsson C, Price JF, Strachan MWJ, Reynolds RM, Tiemeier H, Walker BR. . PLoS Genetics 2014, 10(7), e1004474.
- Chapagain A, Caton PW, Kieswich J, Andrikopoulos P, Nayuni N, Long JH, Harwood SM, Webster SP, Raftery MJ, Thiemermann C, Walker BR, Seckl JR, Corder R, Yaqoob MM. . Proceedings of the National Academy of Sciences of the United States of America 2014, 111(10), 3817-3822.
- Macfarlane DP, Raubenheimer PJ, Preston T, Gray CD, Bastin ME, Marshall I, Iredale JP, Andrew R, Walker BR. . American Journal of Physiology - Gastrointestinal and Liver Physiology 2014, 307(7), G760-G768.
- Iqbal J, Andrew R, Cruden NL, Kenyon CJ, Hughes KA, Newby DE, Hadoke PWF, Walker BR. . Journal of Clinical Endocrinology and Metabolism 2014, 99(3), 915-922.
- Walker BR, Andrew R, Escoubet B, Zennaro M-C. . Journal of Clinical Endocrinology and Metabolism 2014, 99(8), E1586–E1591.
- Upreti R, Hughes KA, Livingstone DEW, Gray CD, Minns FC, Macfarlane DP, Marshall I, Stewart LH, Walker BR, Andrew R. . Journal of Clinical Endocrinology and Metabolism 2014, 99(8), E1397–E1406.
-
Letter
- Davidson CT, Dover AR, McVicar CM, Megaw R, Glenn JV, Hadoke PWF, Stitt AW, Walker BR. . Diabetes and Metabolism 2017, 43(5), 480-483.
-
Reviews
- Devine K, Villalobos E, Kyle CJ, Andrew R, Reynolds RM, Stimson RH, Nixon M, Walker BR. . Nature Reviews Endocrinology 2022.
- Han TS, Walker BR, Arlt W, Ross RJ. . Nature Reviews Endocrinology 2014, 10(2), 115-124.
- Stomby A, Andrew R, Walker BR, Olsson T. . Diabetologia 2014, 57(6), 1100-1110.