Staff Profile
Dr Catherine Meplan
Senior Lecturer
- Email: catherine.meplan@ncl.ac.uk
- Telephone: +44 (0) 191 208 7664
- Address: School of Biomedical Sciences
Faculty of Medical Sciences
缅北禁地
Framlington Place
缅北禁地 upon Tyne
NE2 4HH
Background
Roles and Responsibilities
School
- Senior Lecturer in Genetics, School of Biomedical, Nutritional and Sport Sciences
- Chair of the Biochemistry and Biomedical Genetics Curriculum Committee (2019-2024)
- SBNS MSci Lead (2024-present)
- SBNS EDI Lead (2020-2023)
- Academic Adviser for UCAS graduate Medicine/Dentistry applications (since 2014-2019)
- Pastoral tutor
- Phase II advisor (2029-2024)
- Module leader
- Member of SBNS Board of Studies and MRes Board of Studies, SBNS Board of Examiners, Biomedical Sciences Curriculum Committee, Genetics and Biochemistry Curriculum Committee, Nutrition Sciences Curriculum Committee
- Supervision of UG projects
Research
· PGR supervision: MPhil and MRes students
· Member of the Executive board of the Human Nutrition and Exercise Research Centre (HNERC).
Qualifications
- Fellow of the Higher Education Academy (2016)
- PhD: Université Joseph Fourier, Grenoble, France- Laboratory of Molecular Carcinogenesis, IARC, WHO, Lyon, France. (Dr. P. Hainaut): Study of the metalloregulation of the p53 tumor suppressor protein: consequences in metal-related carcinogenesis.1999
- Master degree in Molecular Biology: Université Joseph Fourier, Grenoble, France- Laboratoire INSERM U309, Institut A. Bonniot, Grenoble, France. (Dr. J. J. Lawrence) Chromatin structure of the promoter of the gene encoding histone H10.1995
- BSc Hons Cell and Molecular biology, Biochemistry and Genetics, Université Joseph Fourier, Grenoble, France, 1994
Previous positions
- Senior Research Associate, ICAMB, 缅北禁地, 2003-2013
- Research Associate, Biomedical Research Centre, Ninewells Hospital. University of Dundee, UK, 2000-2002
Memberships
- Human Nutrition Research Centre/ Human Nutrition and Exercise Research Centre, 缅北禁地, since 2003
- Human Nutrition and Exercise Research Centre executive committee
- NaCre (2024- present)
- Member of the European Nutrigenomics Organisation (NuGO), since 2004
- FMS Educational Research Development and Practice, 缅北禁地
Faculty Role
Deputy Director of EDI (Equality, Diversity& Inclusivity)
Member of :
- Faculty EDI committee (FEDIC)
- Equality project (co-lead Taught programme work stream)
- FMS PGR committee
- Faculty Research and Innovation Committee (FRIC)
- Period dignity group
University role
- EDI lead forum member
- EDI fund review panel
- NU Women member
- 缅北禁地 Educator working group
External Role
External examiner (MSc Human and Molecular Genetics, University of Sheffield, (2019-2023)
Research
- Nutrigenetics and Nutrigenomics approach to the study of Selenium, selenoproteins and Cancer
Teaching
Module Leader
- NUT1004: Fundamental principles of genetics and biochemistry for nutrition
- BGM2002: Biochemistry and Genetics of Signalling and the Cell Cycle
- BMS3020: Chronic Disease
- CMB3004: MSci 3rd year Research Project
- CMB4099: MSci 4th year Research Project
Contribution to other Modules
- BGM1004: Genetics
- NUT1004: Fundamental principles of genetics and biochemistry for nutrition
- BGM2002: Biochemistry and Genetics of Signalling and the Cell Cycle
- BMS2013: Practical and presentation skills in Biomedical Sciences
- CMB1005: Practical Skills in Biomedical & Biomolecular Sciences
- BMS3010: Genetics and Human Disease
- CMB3004: MSci 3rd year Research Project
- CMB4099: MSci 4th year Research Project
Publications
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Articles
- Hughes, DJ, Schomburg, L, Jenab, M, Biessy, C, Méplan, C, Moskal, A, Sun, Q, Demircan, K, Fedirko, V, Weiderpass, E, Mukhtar, M, Olsen, A, Tjønneland, A, Overvad, K, Schulze, M, Haugdahl Nøst, T, Skeie, G, Standahl Olsen, K, Ricceri, F, Grioni, S, Palli, D, Masala, G, Tumino, R, Pasanisi, F, Amiano, P, Colorado Yohar, SM, Agudo, A, Sánchez, MJ, Ardanaz, E, Sund, M, Andersson, A, Perez-Cornago, A, Travis, R, Heath, AK, Dossus, L. . Free Radical Biology and Medicine 2023, 209(2), 381-393.
- Fedirko V, Jenab M, Meplan C, Jones JS, Zhu W, Schomburg L, Siddiq A, Hybsier S, Overvad K, Tjønneland A, Omichessan H, Perduca V, Boutron-Ruault MC, Kühn T, Katzke V, Aleksandrova K, Trichopoulou A, Karakatsani A, Kotanidou A, Tumino R, Panico S, Masala G, Agnoli C, Naccarati A, Bueno-de-Mesquita B, Vermeulen RCH, Weiderpass E, Skeie G, Haugdahl Nøst T, Lujan-Barroso L, Quirós JR, Huerta JM, Rodríguez-Barranco M, Barricarte A, Gylling B, Harlid S, Bradbury KE, Wareham N, Khaw KT, Gunter M, Murphy N, Freisling H, Tsilidis K, Aune D, Riboli E, Hesketh JE, Hughes DJ. . Nutrients 2019, 11(4), 935.
- Méplan C, Johnson IT, Polley ACJ, Cockell S, Bradburn DM, Commane DM, Arasaradnam RP, Mulholland F, Zupanic A, Mathers JC, Hesketh J. . The FASEB Journal 2016, 30(8), 2812-2825.
- Zupanic A, Meplan C, Huguenin GVB, Hesketh JE, Shanley DP. . RNA 2016, 22(7), 1076-1084.
- Hughes DJ, Fedirko V, Jenab M, Schomburg L, Méplan C, Freisling H, Bueno-de-Mesquita HB, Hybsier S, Becker NP, Czuban M, Tjønneland A, Outzen M, Boutron-Ruault MC, Racine A, Bastide N, Kühn T, Kaaks R, Trichopoulos D, Trichopoulou A, Lagiou P, Panico S, Peeters PH, Weiderpass E, Skeie G, Dagrun E, Chirlaque MD, Sánchez MJ, Ardanaz E, Ljuslinder I, Wennberg M, Bradbury KE, Vineis P, Naccarati A, Palli D, Boeing H, Overvad K, Dorronsoro M, Jakszyn P, Cross AJ, Quirós JR, Stepien M, Kong SY, Duarte-Salles T, Riboli E, Hesketh JE. . International Journal of Cancer 2015, 136(5), 1149-1161.
- Mistry HD, Gill CA, Kurlak LO, Seed PT, Hesketh JE, Meplan C, Schomburg L, Chappell LC, Morgan L, Poston L, SCOPE Consortium. . Free Radical Biology and Medicine 2015, 78, 147-155.
- Zupanic A, Méplan C, Grellscheid SN, Mathers JC, Kirkwood TBL, Hesketh J, Shanley D. . RNA 2014, 20(10), 1507-1518.
- Méplan C, Dragstead LO, Ravn-Haren G, Tjønneland A, Vogel U, Hesketh J. . PLoS ONE 2013, 8(9), e73316.
- Méplan C, Rohrmann S, Steinbrecher A, Schomburg L, Jansen E, Linseisen J, Hesketh J. . PLoS One 2012, 7(11), e48709.
- Gong G, Meplan C, Gautrey H, Hall J, Hesketh JE. . Genes & Nutrition 2012, 7(2), 167-178.
- Mathers JC, Meplan C, Hesketh JE. . International Journal for Vitamin and Nutrition Research 2010, 80(4-5), 314-318.
- Meplan C, Hughes DJ, Pardini B, Naccarati A, Soucek P, Vodickova L, Hlavata I, Vrana D, Vodicka P, Hesketh JE. . Carcinogenesis 2010, 31(6), 1074-1079.
- Steinbrecher A, Méplan C, Hesketh J, Schomburg L, Endermann T, Jansen E, Åkesson B, Rohrmann S, Linseisen J. . Cancer Epidemiology Biomarkers and Prevention 2010, 19(11), 2958-2968.
- Leung WC, Hessel S, Méplan C, Flint J, Oberhauser V, Tourniaire F, Hesketh JE, von Lintig J, Lietz G. . FASEB Journal 2009, 23(4), 1041-1053.
- Meplan C, Nicol F, Burtle BT, Crosley LK, Arthur JR, Mathers JC, Hesketh JE. . Antioxidants & Redox Signaling 2009, 11(11), 2631-2640.
- Kipp A, Banning A, van Schothorst EM, Meplan C, Schomburg L, Evelo C, Coort S, Gaj S, Keijer J, Hesketh J, Brigelius Flohe R. . Molecular Nutrition & Food Research 2009, 53(12), 1561-1572.
- Pagmantidis V, Meplan C, Van Schothorst EM, Keijer J, Hesketh JE. . American Journal of Clinical Nutrition 2008, 87(1), 181-189.
- Meplan C, Crosley LK, Nicol F, Horgan GW, Mathers JC, Arthur JR, Hesketh JE. . American Journal of Clinical Nutrition 2008, 87(4), 1019-1027.
- Meplan C, Crosley LK, Nicol F, Beckett GJ, Howie AF, Hill KE, Horgan G, Mathers JC, Arthur JR, Hesketh JE. . FASEB Journal 2007, 21(12), 3063-3074.
- Crosley LK, Meplan C, Nicol F, Rundlof AK, Arner ESJ, Hesketh JE, Arthur JR. . Archives of Biochemistry and Biophysics 2007, 459(2), 178-188.
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Book Chapters
- Meplan C. Association of Single Nucleotide Polymorphisms in Selenoprotein Genes with Cancer Risk. In: Laurent Chavatte, ed. Selenoproteins -Methods and Protocols. Springer, 2018, pp.313-324. In Preparation.
- Méplan C, Hesketh J. . In: Vincenzo Zappia, Salvatore Panico, Gian Luigi Russo, Alfredo Budillon, Fulvio Della Ragione, ed. Advances in Nutrition and Cancer. Berlin: Springer-Verlag, 2014, pp.145-166.
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Conference Proceedings (inc. Abstracts)
- Hughes DJ, Fedirko V, Jones JS, Schomburg L, Hybsier S, Meplan C, Hesketh JE, Riboli E, Jenab M. . In: Global Advances in Selenium Research from Theory to Application - Proceedings of the 4th International Conference on Selenium in the Environment and Human Health, 2015. 2015, Sao Paulo, Brazil: CRC Press/Balkema.
- Hughes DJ, Fedirko V, Jones JS, Meplan C, Schomburg L, Hybsier S, Riboli E, Hesketh JE, Jenab M, EPIC Grp. . In: European Cancer Congress 2015. 2015, Vienna, Austria: Elsevier.
- Hughes DJ, Jenab M, Meplan C, Schomburg L, Prehn J, Hesketh JE. . In: 22nd Biennial Congress of the European Association for Cancer Research. 2012, Barcelona, Spain: Pergamon.
- Meplan C, Crosley K, Nicol F, Arthur JR, Mathers JC, Hesketh JE. . In: Proceedings of the Nutrition Society. 2006, Aberdeen, Scotland: Cambridge University Press.
- Meplan C, Crosley K, Nicol F, Beckett GJ, Arthur JR, Mathers JC, Hesketh JE. . In: Scientific Meeting of the Nutrition Society. 2006, Aberdeen, UK: Proceedings of the Nutrition Society: Cambridge University Press.
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Reviews
- Bermano G, Meplan C, Merce DK, Hesketh JE. . British Journal of Nutrition 2021, 125(6), 618-627.
- Meplan C, Hughes DJ. . Nutrients 2020, 12(4), 1049.
- Meplan C. Selenium and Chronic Diseases: A Nutritional Genomics Perspective. Nutrients 2015, 7(5), 3621–3651. In Preparation.
- Méplan C, Hesketh J. The influence of selenium and selenoprotein gene variants on colorectal cancer risk. Mutagenesis 2012, 27, 117-186.
- van Ommen B, El-Sohemy A, Hesketh J, Kaput J, Fenech M, Evelo CT, McArdle HJ, Bouwman J, Lietz G, Mathers JC, Fairweather-Tait S, van Kranen H, Elliott R, Wopereis S, Ferguson LR, Meplan C, Perozzi G, Allen L, Rivero D, Micronutrient Genomics Project Wor. . Genes & Nutrition 2010, 5(4), 285-296.