Staff Profile
Professor David Jones
Professor of Liver Immunology
- Email: david.jones@ncl.ac.uk
- Telephone: +44 (0) 191 208 7572
- Personal Website:
- Address: NIHR 缅北禁地 Biomedical Research Centre
缅北禁地 upon Tyne NHS Foundation Trust & 缅北禁地
Campus for Ageing and Vitality
缅北禁地 upon Tyne
NE4 5PL
I am NIHR Dean for Faculty Trainees and an active researcher in the area of Autoimmune Liver Disease, with a particular focus on the impact of the diseases on patients and how we can improve outcomes through the development and evaluation of new treatment approaches. I am the PI for the UK-PBC national research consortium (www.uk-pbc.com). Working with 缅北禁地 colleagues I am the first Director for the 缅北禁地 Centre for Research Excellence in Rare Disease
My research interest was originally in the nature, antigen specificity, and mechanisms of control of T-cell response to autoantigens in the autoimmune liver disease primary biliary cirrhosis (now primary biliary cholangitis (PBC)). This has developed into a broader interest in mechanisms of T-cell control, and the potential role of mucosal immune-modulation in altering the nature of the immune response in terms of both vaccine development, and immunotherapy for autoimmune disease.
As the significance of the role played by target cells in autoimmune disease in terms of function loss and subsequent fibrosis development has come to be appreciated I developed a strand of research exploring mechanisms of biliary epithelial cell damage and loss. This work also has important implications for the development of novel treatments. Interest in the mechanisms underpinning autoimmune disease also led to an interest in the role played by genetic factors in disease pathogenesis and expression in PBC, initially in the context of candidate gene association and latterly in a Wellcome Trust funded GWAS programme which represented the largest single study performed worldwide in PBC to date. This work has evolved into a substantial programme of stratified medicine research in PBC (funded by the MRC) and more recently in autoimmune hepatitis (funded by the NIHR).
My clinical research has been into aspects of the symptomatology, complications, therapy and outcomes in primary biliary cholangitis and other forms of autoimmune liver disease. I have a particular interest in the area of quality of life assessment in PBC, and the importance of development of QOL outcome measures for use in the assessment of novel therapies in PBC. This work has highlighted the importance of fatigue in the lives of PBC patients and has informed a novel experimental medicine programme exploring the mechanisms of fatigue using fMRI approaches allied to in vitro studies. This work, which has identified systemic bio-energetic abnormalities in PBC has contributed to a paradigm shift in our understanding of the nature and impact of this disease. This work has also shed important light on potential pathogenetic mechanisms for fatigue in other disease settings including chronic fatigue syndrome where I have an ongoing programme of work. I have significant experience as CI and PI in phase II and phase III clinical trials in PBC. I developed the leading PROM for use in PBC (the PBC-40) and have extensive experience of trial protocol development in PBC. This involvement culminated in my leading the team that got FDA approval for the first new therapy for PBC in 20 years, and the first ever stratified therapeutic agent in liver disease, in spring 2016. The stratified approach to the management of PBC has now been implemented into NHS practice. The trials programme has finally brought together the clinical and basic science aspects of my research.
The UK-PBC consortium (www.UK-PBC.com) that I lead has been instrumental in increasing our understanding of the nature of risk in PBC and, crucially, leveraging that knowledge in innovative clinical trials using the UK-PBC patient cohort.
- Dyson JK, Jeffreys Jones DE. . Gastroenterology 2021, 160(3), 649-651.
- Rice S, Albani V, Minos D, Fattakhova G, Mells GF, Carbone M, Flack S, Varvaropoulou N, Badrock J, Spicer A, Sandford RN, Shirley MDF, Coughlan D, Hirschfield G, Taylor-Robinson SD, Vale L, Jones DEJ. . Clinical Gastroenterology and Hepatology 2021, 19(4), 768-776.e10.
- Phaw NA, Leighton J, Dyson JK, Jones DE. . Expert Review of Gastroenterology and Hepatology 2021, 15(3), 235-241.
- Montali L, Gragnano A, Miglioretti M, Frigerio A, Vecchio L, Gerussi A, Cristoferi L, Ronca V, D'Amato D, O'Donnell SE, Mancuso C, Luca M, Yagi M, Reig A, Jopson L, Pilar S, Jones D, Pares A, Mells G, Tanaka A, Carbone M, Invernizzi P. . Journal of Translational Autoimmunity 2021, 4, 100081.
- Sivakumar M, Gandhi A, Shakweh E, Li YM, Safinia N, Smith BC, Marshall A, Turner L, Mukhopadhya A, Haboubi HN, Vincent R, Tan HK, Alrubaiy L, Jones DEJ. . Frontline Gastroenterology 2021, 13(1), 32-38.
- Alrubaiy L, Mells G, Flack S, Bosomworth H, Hutchings H, Williams J, Jones D. . Alimentary Pharmacology and Therapeutics 2020, 51(1), 183-183.
- Rice S, Albani V, Minos D, Fattakhova G, Mells F, Carbone M, Flack S, Varvaropoulou N, Badrock J, Spice A, Sandford R, Shirley M, Coughlan D, Hirschfield G, Taylor-Robinson S, Vale L, Jones D. Effects of Primary Biliary Cholangitis on Quality of Life and Health Care Costs in the United Kingdom. Clinical Gastroenterology and Hepatology 2020, S1542-3565(20), epub ahead of print.
- Phaw NA, Dyson JK, Jones D. . Expert Opinion on Emerging Drugs 2020, 25(2), 101-112.
- Carbone M, D'Amato D, Hirschfield GM, Jones DEJ, Mells GF. . Alimentary Pharmacology and Therapeutics 2020, 51(1), 192-193.
- McMeekin P, Lendrem DW, Lendrem BC, Pratt AG, Peck R, Isaacs JD, Jones D. . Drug Discovery Today 2020, 25(3), 480-484.
- Dropmann A, Dooley S, Dewidar B, Hammad S, Dediulia T, Werle J, Hartwig V, Ghafoory S, Woelfl S, Korhonen H, Janicot M, Wosikowski K, Itzel T, Teufel A, Schuppan D, Stojanovic A, Cerwenka A, Nittka S, Piiper A, Gaiser T, Beraza N, Milkiewicz M, Milkiewicz P, Brain JG, Jones DEJ, Weiss TS, Zanger UM, Ebert M, Meindl-Beinker NM. . Gut 2020, 6(9), 1677-1690.
- Leitch AC, Abdelghany TM, Probert PM, Dunn MP, Meyer SK, Palmer JM, Cooke MP, Blake LI, Morse K, Rosenmai AK, Oskarsson A, Bates L, Figueiredo RS, Ibrahim I, Wilson C, Abdelkader NF, Jones DE, Blain PG, Wright MC. . Food and Chemical Toxicology 2020, 136, 111069.
- Dyson JK, Jones DEJ. . Journal of Hepatology 2020, 73(3), 499-501.
- Phaw NA, Dyson JK, Mells G, Jones D. . Digestive Diseases and Sciences 2021, 66, 2380-2386.
- Hegade VS, Pechlivanis A, McDonald JAK, Rees D, Corrigan M, Hirschfield GM, Taylor-Robinson SD, Holmes E, Marchesi JR, Kendrick S, Jones DE. . Liver International 2019, 39(5), 967-975.
- Chapman MH, Thorburn D, Hirschfield GM, Webster GGJ, Rushbrook SM, Alexander G, Collier J, Dyson JK, Jones DEJ, Patanwala I, Thain C, Walmsley M, Pereira SP. . Gut 2019, 68(8), 1356-1378.
- Hegade VS, Jones DE. . Medicine 2019, 47(12), 818-821.
- Martin ML, Stassek L, Blum SI, Joshi AV, Jones D. . Journal of Patient-Reported Outcomes 2019, 3, 2.
- Swain MG, Jones DEJ. . Liver International 2019, 39(1), 6-19.
- Khanna A, Hegade VS, Jones DE. . Current Hepatology Reports 2019, 18, 127-133.
- Phaw NA, Jones DEJ. . Digestive Diseases and Sciences 2019, 64, 2075-2077.
- Bernts LHP, Jones DEJ, Kaatee MM, Lohse AW, Schramm C, Sturm E, Drenth JPH. . Orphanet Journal of Rare Diseases 2019, 14(1), 169.
- Hegade VS, Mells GF, Fisher H, Kendrick S, DiBello J, Gilchrist K, Alexander GJ, Hirschfield GM, Sandford RN, Jones DEJ. . Clinical Gastroenterology and Hepatology 2019, 17(7), 1379-1387.e3.
- Hussain AB, Samuel R, Hegade VS, Jones DE, Reynolds NJ. . British Journal of Dermatology 2019, 181(6), 1138-1145.
- Khanna A, Jopson L, Howel D, Bryant A, Blamire A, Newton JL, Jones DE. . Hepatology 2019, 70(5), 1646-1657.
- Chaytor L, Simcock M, Nakjang S, Heath R, Walker L, Robson C, Jones D, Gaughan L. . Molecular Cancer Research 2019, 17(6), 1264-1278.
- Jones DEJ, Sturm E, Lohse AW. . Journal of Hepatology 2018, 68(3), 577-585.
- Darlay R, Ayers KL, Mells GF, Hall LS, Liu JZ, Almarri MA, Alexander GJ, Jones DE, Sandford RN, Anderson CA, Cordell HJ. . PLOS Genetics 2018, 14(12), e1007833.
- Jopson L, Khanna A, Peterson P, Rudell E, Corrigan M, Jones D. . Digestive Diseases and Sciences 2018, 63(10), 2547-2554.
- Jones DE, Hegade VS. . New England Journal of Medicine 2018, 379(10), 984-985.
- Probert PM, Leitch AC, Dunn MP, Meyer SK, Palmer JM, Abdelghany TM, Lakey AF, Cooke MP, Talbot H, Wills C, McFarlane W, Blake LI, Rosenmai AK, Oskarsson A, Figueiredo R, Wilson C, Kass GE, Jones DE, Blain PG, Wright MC. . Journal of Hepatology 2018, 69(5), 1123-1135.
- Liaskou E, Patel SR, Webb G, Bagkou Dimakou D, Akiror S, Krishna M, Mells G, Jones DE, Bowman SJ, Barone F, Fisher BA, Hirschfield GM. . Journal of Autoimmunity 2018, 94, 143-155.
- Dyson JK, Wong LL, Bigirumurame T, Hirschfield GM, Kendrick S, Oo YH, Lohse AW, Heneghan MA, Jones DEJ. . Alimentary Pharmacology and Therapeutics 2018, 48(9), 951-960.
- Dyson JK, Beuers U, Jones DEJ, Lohse AW, Hudson M. . The Lancet 2018, 391(10139), 2547-2559.
- Khanna A, Jopson L, Howel D, Bryant A, Blamire A, Newton JL, Wilkinson J, Steel AJ, Bainbridge J, Stefanetti R, Cassidy S, Houghton D, Jones DE. . Efficacy and Mechanism Evaluation 2018, 5(2), 1-78.
- Khanna A, Leighton J, Lee Wong L, Jones DE. . Best Practice and Research: Clinical Gastroenterology 2018, 34-35, 41-47.
- Hirschfield GM, Dyson JK, Alexander GJM, Chapman MH, Collier J, Hubscher S, Patanwala I, Pereira SP, Thain C, Thorburn D, Tiniakos D, Walmsley M, Webster G, Jones DEJ. . Gut 2018, 67(9), 1568-1594.
- Wong LL, Fisher HF, Stocken DD, Rice S, Khanna A, Heneghan MA, Oo YH, Mells G, Kendrick S, Dyson JK, Jones DEJ. . Hepatology 2018, 68(4), 1487-1497.
- Seeberg T, Orr J, Austad H, Roed M, Dalgard S, Houghton D, Jones D, Strisland F. . IEEE Transactions on Biomedical Engineering 2017, 64(7), 1469-1478.
- Lamb CA, Mansfield JC, Tew GW, Gibbons D, Long AK, Irving P, Diehl L, Eastham-Anderson J, Price MB, O'Boyle G, Jones DEJ, O'Byrne S, Hayday A, Keir ME, Egen JG, Kirby JA. . Journal of Crohn's and Colitis 2017, 11(5), 610-620.
- Hegade VS, Jones DEJ, Hirschfield GM. . Digestive Diseases 2017, 35(3), 267-274.
- Hegade VS, Kendrick SF, Dobbins RL, Miller SR, Thompson D, Richards D, Storey J, Dukes GE, Corrigan M, Oude-Elferink RP, Beuers U, Hirschfield GM, Jones DEJ. . The Lancet 2017, 389(10074), 1114-1123.
- Khanna A, Jones DE. . Therapeutic Advances in Gastroenterology 2017, 10(10), 791-803.
- Jones DEJ, Boudes P, Swain M, Bowlus C, Galambos M, Bacon B, Doerffel Y, Gitlin N, Gordon S, Odin J, Sheridan D, Wörns M-A, Clark V, Corless L, Hartmann H, Jonas ME, Kremer A, Mells G, Buggisch P, Freilich B, Levy C, Vierling J, Bernstein D, Hartleb M, Janczewska E, Rochling F, Shah H, Shiffman M, Smith J, Choi Y-J, Steinberg A, Varga M, Chera H, Martin R, McWherter C, Hirschfield G. . Lancet Gastroenterology and Hepatology 2017, 2(10), 716-726.
- Mells GF, Jones DEJ. . The Lancet Gastroenterology and Hepatology 2017, 2(5), 319-321.
- Wong LL, Hegade VS, Jones DEJ. . Digestive Diseases 2017, 35(4), 359-366.
- Hegade VS, Bolier R, Oude Elferink RPJ, Beuers U, Kendrick S, Jones DEJ. . Frontline Gastroenterology 2016, 7(3), 158-166.
- Hegade VS, Kendrick SFW, Dobbins RL, Miller SR, Richards D, Storey J, Dukes G, Gilchrist K, Vallow S, Alexander GJ, Corrigan M, Hirschfield GM, Jones DEJ. . BMC Gastroenterology 2016, 16, 71.
- Hardie C, Green K, Jopson L, Millar B, Innes B, Pagan S, Tiniakos D, Dyson J, Haniffa M, Bigley V, Jones DE, Brain J, Walker LJ. . EBioMedicine 2016, 14, 65-73.
- Grover VPB, Southern L, Dyson JK, Kim JU, Crossey MME, Wylezinska-Arridge M, Patel N, Fitzpatrick JA, Bal-Bok A, Waldman AD, Mells GF, Chapman RW, Jones DEJ, Taylor-Robinson SD. . Alimentary Pharmacology & Therapeutics 2016, 44(9), 936-945.
- Jones DEJ, Hansen BE. . Alimentary Pharmacology and Therapeutics 2016, 43(5), 648-649.
- Hirschfield G, Vale L, Mells G, Shapiro D, Jones D. . In: British Society of Gastroenterology, Annual General Meeting. 2016, Liverpool: BMJ Group.
- Hegade VS, Khanna A, Walker LJ, Wong LL, Dyson JK, Jones DEJ. . Digestive Diseases and Sciences 2016, 61(10), 2037-3044.
- Hegade VS, Speight RA, Etherington RE, Jones DEJ. . Therapeutic advances in gastroentology 2016, 9(3), 376-391.
- Jones DEJ. . Expert Review of Gastreoenterology & Hepatology 2016, 10(10), 1091-1099.
- Nevens F, Andreone P, Mazzella G, Strasser S, Bowlus C, Invernizzi P, Drenth J, Pockros P, Regula J, Beuers U, Trauner M, Jones DEJ, Floreani A, Hohenester S, Luketic V, Shiffman M, Erpecum K, Vargas V, Vincent C, Hirschfield GM, Shah H, Hansen B, Lindor KD, Marschall H-U, Hooshmand-Rad R, Marmon T, Sheeron S, Pencek R, MacConell L, Pruzanski M, Shapiro D. . The New England Journal of Medicine 2016, 375, 631-643.
- Probert PM, Palmer JM, Alhusainy W, Amer AO, Rietjens IMCM, White SA, Jones DE, Wright MC. . Toxicology Letters 2016, 243, 98-110.
- Dyson JK, Wilkinson N, Jopson L, Mells G, Bathgate A, Heneghan MA, Neuberger J, Hirschfield M, Ducker SJ, The UK-PBC Consortium, Sandford R, Alexander G, Stocken D, Jones DEJ. . Alimentary Pharmacology & Therapeutics 2016, 44(10), 1039–1050.
- Hegade VS, Krawczyk M, Kremer AE, Kuczka J, Gaouar F, Kuiper EMM, van Buuren HR, Lammert F, Corpechot C, Jones DEJ. . Alimentary Pharmacology and Therapeutics 2016, 43(2), 294-302.
- Carbone M, Sharp SJ, Flack S, Paximadas D, Spiess K, Adgey C, Griffiths L, Lim R, Trembling P, Williamson K, Wareham NJ, Aldersley M, Bathgate A, Burroughs AK, Heneghan MA, Neuberger JM, Thorburn D, Hirschfield GM, Cordell HJ, Alexander GJ, Jones DEJ, Sandford RN, Mells GF, UK-PBC Consortium. . Hepatology 2016, 63(3), 930-950.
- Jopson L, Dyson JK, Jones DEJ. . Clinics in Liver Disease 2016, 20(1), 131-142.
- James K, Al-Ali S, Tarn J, Cockell SJ, Gillespie CS, Hindmarsh V, Locke J, Mitchell S, Lendrem D, Bowman S, Price E, Pease CT, Emery P, Lanyon P, Hunter JA, Gupta M, Bombardieri M, Sutcliffe N, Pitzalis C, McLaren J, Cooper A, Regan M, Giles I, Isenberg D, Saravanan V, Coady D, Dasgupta B, McHugh N, Young-Min S, Moots R, Gendi N, Akil M, Griffiths B, The UK Primary Sjögren’s Syndrome registry, Wipat A, Newton J, Jones DE, Isaacs J, Hallinan J, Ng W-F. . PLoS ONE 2015, 10(12), e0143970.
- Beuers U, Gershwin ME, Gish RG, Invernizzi P, Jones DEJ, Lindor K, Ma X, Mackay IR, Pares A, Tanaka A, Vierling JM, Poupon R. . Hepatology 2015, 62(5), 1620-1622.
- Beuers U, Gershwin ME, Gish RG, Invernizzi P, Jones DEJ, Lindor K, Ma X, Mackay IR, Pares A, Tanaka A, Vierling JM, Poupon R. . Gut 2015, 64(11), 1671-1672.
- Beuers U, Gershwin ME, Gish RG, Invernizzi P, Jones DEJ, Lindor K, Ma X, Mackay IR, Pares A, Tanaka A, Vierling JM, Poupon R. . Digestive and Liver Disease 2015, 47(11), 924-926.
- Beuers U, Gershwin ME, Gish RG, Invernizzi P, Jones DEJ, Lindor K, Ma X, Mackay IR, Pares A, Tanaka A, Vierling JM, Poupon R. . Journal of Hepatology 2015, 63(5), 1285-1287.
- Beuers U, Gershwin ME, Gish RG, Invernizzi P, Jones DEJ, Lindor K, Ma X, Mackay IR, Pares A, Tanaka A, Vierling JM, Poupon R. . Clinics and Research in Hepatology and Gastroenterology 2015, 39(5), e57-e59.
- Beuers U, Gershwin ME, Gish RG, Invernizzi P, Jones DEJ, Lindor K, Ma X, Mackay IR, Pares A, Tanaka A, Vierling JM, Poupon R. . American Journal of Gastroenterology 2015, 110(11), 1536-1538.
- Beuers U, Gershwin ME, Gish RG, Invernizzi P, Jones DEJ, Lindor K, Ma X, Mackay IR, Pares A, Tanaka A, Vierling JM, Poupon R. . Gastroenterology 2015, 149(6), 1627-1629.
- Beuers U, Gershwin ME, Gish RG, Invernizzi P, Jones DEJ, Lindor K, Ma X, Mackay IR, Pares A, Tanaka A, Vierling JM, Poupon R. . Clinical Gastroenterology and Hepatology 2015, 13(11), 1867-1869.
- Hegade VS, Jones DEJ. . Medicine 2015, 43(11), 666-668.
- Hansen BE, Lammers WJ, Jones D, van Buuren HR, Mells GF, Carbone M. . In: 66th Annual Meeting of the American Association for the Study of Liver Diseases: The Liver Meeting 2015. 2015, San Francisco, CA, USA: Wiley.
- Hegade VS, Kendrick SFW, Jones DEJ. . Clinical Medicine 2015, 15(4), 351-357.
- Jopson L, Jones DEJ. . Digestive Diseases 2015, 33(Suppl 2), 109-114.
- Dyson JK, Elsharkawy AM, Lamb CA, Al-Rifai A, Newton JL, Jones DE, Hudson M. . Liver International 2015, 35(5), 1633-1641.
- Hegade VS, Kendrick SFW, Rehman J, Jones DEJ. . British Journal of General Practice 2015, 65(635), e418-e420.
- Orr JG, Thomas RC, Jones D, Hudson M. . In: The Liver Meeting 2015: 66th Annual Meeting of the American Association for the Study of Liver Diseases. 2015, San Francisco: John Wiley & Sons, Inc.
- Jopson L, Hegade V, Mells G, Sandford R, Jones DE. . In: 50th Annual Meeting of the European Association for the Study of the Liver, International Liver Congress 2015. 2015, Vienna, Austria: Elsevier.
- Dyson JK, Hirschfield GM, Adams DH, Beuers U, Mann DA, Lindor KD, Jones DEJ. . Nature Reviews Gastroenterology & Hepatology 2015, 12(3), 147-158.
- Orr JG, Hudson M, McNeil CJ, Jones DE. . In: 50th The International Liver Congress 2015. 2015, Vienna, Austria: Elsevier.
- Dyson JK, Webb G, Hirschfield GM, Lohse A, Beuers U, Lindor K, Jones DEJ. . Journal of Hepatology 2015, 62(1), 208-218.
- Chatterjee S, Oppong KW, Scott JS, Jones DE, Charnley RM, Manas DM, Jaques BC, White SA, French JJ, Sen GS, Haugk B, Nayar MK. . Journal of Gastrointestinal and Liver Diseases 2014, 23(2), 179-185.
- Orr J, Hudson M, Jones D. . In: British Society of Gastroenterology Annual General Meeting. 2014, Manchester, UK: BMJ Publishing Group.
- Dyson JK, Jones DEJ. . Clinical Liver Disease 2014, 3(3), 43-68.
- Patanwala I, King MJ, Barrett DA, Rose J, Jackson R, Hudson M, Philo M, Dainty JR, Wright AJA, Finglas PM, Jones DE. . American Journal of Clinical Nutrition 2014, 100(2), 593-599.
- Orr JG, Homer T, Ternent L, Newton J, McNeil CJ, Hudson M, Jones DEJ. . Journal of Hepatology 2014, 61(5), 1158-1165.
- Orr J G., Homer T, Ternent L, Newton J, McNeil C J., Hudson M, Jones D E.J. . Journal of Hepatology 2014, 61(5), 1158–1165.
- Frith J, Ng WF, Day CP, Payne B, Sheerin N, Gorman G, Jones D, Newton JL. . International Journal of Cardiology 2014, 174(3), 861-862.
- Griffiths L, Jones DE. . Digestive Diseases 2014, 32(5), 615-625.
- Bodenheimer HC, Jones DEJ, Peterson P, Rudell E. . In: The International Liver Congress 2014: 49th Annual Meeting of the European Association for the Study of the Liver. 2014, London: Elsevier BV.
- Carbone M, Bufton S, Jones DE, Neuberger JM. . Journal of Hepatology 2014, 60(6), 1328-1239.
- Griffiths L, Dyson JK, Jones DEJ. . Seminars in Liver Disease 2014, 34(3), 318-328.
- Pitts AC, Palmer JM, Dyson JK, Ducker S, Griffiths L, Jones DEJ, Kirby JA. . In: The International Liver Congress 2014: 49th Annual Meeting of the European Association for the Study of the Liver. 2014, London: Elsevier BV.
- Pitts AC, Palmer JM, Jones DE, Dyson JK, Griffiths L, Ducker S, Kirby JA. . In: British Society of Gastroenterology Annual General Meeting. 2014, Manchester, UK: BMJ Publishing Group.
- Patanwala I, McMeekin P, Walters R, Mells G, Alexander G, Newton J, Shah H, Coltescu C, Hirschfield GM, Hudson M, Jones D. . Journal of Hepatology 2013, 59(2), 327-335.
- Elliott C, Frith J, Day CP, Jones DEJ, Newton JL. . Digestive Diseases and Sciences 2013, 58(8), 2383-2391.
- Zalewski P, Jones D, Lewis I, Frith J, Newton JL. . American Journal of Physiology - Gastrointestinal & Liver Physiology 2013, 305, G393-7.
- Anderson K, Jones DEJ, Wilton K, Newton JL. . Liver International 2013, 33(2), 239-243.
- Carbone M, Mells GF, Pells G, Dawwas MF, Newton JL, Heneghan MA, Neuberger JM, Day DB, Ducker SJ, Sandford RN, Alexander GJ, Jones DEJ, UK PBC Consortium. . Gastroenterology 2013, 144(3), 560-569.
- Carbone M, Bufton S, Monaco A, Griffiths L, Jones DE, Neuberger JM. . Journal of Hepatology 2013, 59(3), 490-494.
- Mells G, Carbone M, Pells G, Newton J, Bathgate A, Burroughs A, Heneghan M, Neuberger J, Day D, Ducker S, Sandford R, Alexander G, Jones D, UK-PBC Consortium. . Journal of Hepatology 2013, 58(1), 67–73.
- Mells G, Pells G, Newton JL, Bathgate A, Burroughs A, Heneghan M, Neuberger JM, Day D, Ducker SJ, Sandford R, Alexander G, Jones DEJ. . Hepatology 2013, 58(1), 273-283.
- Hollingsworth KG, Macgowan GA, Morris L, Bates MG, Taylor R, Jones DE, Newton JL, Blamire AM. . Journal of Applied Physiology 2012, 112(12), 2043-2048.
- Frith J, Fattakhova G, Jones DEJ, Henderson E, Wilton K, Day CP, Newton JL. . Gut 2012, 61(7), 1101-1103.
- Liu JZ, Almarri MA, Gaffney DJ, Mells GF, Jostins L, Cordell HJ, Ducker SJ, Day DB, Heneghan MA, Neuberger JM, Donaldson PT, Bathgate AJ, Burroughs A, Davies MH, Jones DE, Alexander GJ, Barrett JC, Sandford RN, Anderson CA. . Nature Genetics 2012, 44(10), 1137-1141.
- Frith J, Kerr S, Robinson L, Elliott CS, Wilton K, Jones DEJ, Day CP, Newton JL. . Digestive Diseases and Sciences 2012, 57(10), 2697-2702.
- Hale M, Newton JL, Jones DEJ. . British Medical Journal 2012, 345(1), e7004.
- Jones DEJ, Hollingsworth KG, Jakovljevic DG, Fattakhova G, Pairman J, Blamire AM, Trenell MI. . European Journal of Clinical Investigation 2012, 42(2), 186-194.
- Leckie P, Tritto G, Mookerjee R, Davies N, Jones D, Jalan R. . Alimentary Pharmacology and Therapeutics 2012, 35(6), 696-704.
- Jones DEJ. . Hepatology 2012, 56(4), 1194-1196.
- Prentis JM, Trenell MI, Jones DJ, Lees T, Clarke M, Snowden CP. . Journal of Vascular Surgery 2012, 56(6), 1564-1570.
- Jones DEJ. . Journal of Hepatology 2011, 55(4), 750-752.
- Newton JL, Elliott C, Frith J, Ghazala C, Pairman J, Jones DEJ. . European Journal of Gastroenterology and Hepatology 2011, 23(7), 566-572.
- Mells GF, Floyd JAB, Morley KI, Cordell HJ, Franklin CS, Shin SY, Heneghan MA, Neuberger JM, Donaldson PT, Day DB, Ducker SJ, Muriithi AW, Wheater EF, Hammond CJ, Dawwas MF, Jones DE, Peltonen L, Alexander GJ, Sandford RN, Anderson CA. . Nature Genetics 2011, 43(4), 329-U151.
- Miller N, Deane K, Jones D, Noble E, Gibb C. . International Journal of Language and Communication Disorders 2011, 46(2), 189-201.
- Elliott C, Frith J, Pairman J, Jones DEJ, Newton JL. . Transplant International 2011, 24(6), 588-595.
- Jones D, Newton J. . Journal of Hepatology 2011, 55(3), 729-730.
- Miller N, Noble E, Jones D, Deane K, Gibb C. . International Journal of Language and Communication Disorders 2011, 46(2), 179-188.
- Jones DEJ, Newton JL. . Hepatology 2011, 53(2), 717-718.
- Frith J, Kerr S, Robinson L, Elliott C, Ghazala C, Wilton K, Pairman J, Jones D, Newton J. . QJM 2010, 103(3), 153-161.
- Hollingsworth KG, Jones DE, Aribisala BS, Thelwall PE, Taylor R, Newton JL, Blamire AM. . Journal of Magnetic Resonance Imaging 2009, 29(4), 780-784.
- Newton JL, Pairman J, Sutcliffe K, Wilton K, Jones DEJ. . Clinical Gastroenterology and Hepatology 2008, 6(2), 228-233.
- Newton JL, Hollingsworth KG, Taylor R, El-Sharkawy AM, Khan ZU, Pearce R, Sutcliffe K, Okonkwo O, Davidson A, Burt J, Blamire AM, Jones DEJ. . Hepatology 2008, 48(2), 541-549.
- Rygiel KA, Robertson H, Marshall HL, Pekalski M, Zhao L, Booth TA, Jones DEJ, Burt AD, Kirby JA. . Laboratory Investigation 2008, 88(2), 112-123.
- Newton JL, Jones DEJ, Henderson E, Kane L, Wilton K, Burt AD, Day CP. . Gut 2008, 57(6), 807-813.
- Hollingsworth KG, Newton JL, Taylor R, McDonald C, Palmer JM, Blamire AM, Jones DEJ. . Clinical Gastroenterology and Hepatology 2008, 6(9), 1041-1048.
- Walden HR, Kirby JA, Yeaman SJ, Gray J, Jones DE, Palmer JM. . Hepatology 2008, 48(6), 1874-1884.
- Jones DEJ, Newton JL. . Alimentary Pharmacology and Therapeutics 2007, 25(4), 471-476.
- Newton JL, Davidson A, Kerr S, Bhala N, Pairman J, Burt J, Jones DEJ. . European Journal of Gastroenterology and Hepatology 2007, 19(2), 125-132.
- Robertson H, Kirby JA, Yip WW, Jones DEJ, Burt AD. . Hepatology 2007, 45(4), 977-981.
- Jones DEJ. . Medicine 2007, 35(2), 96-98.
- Donaldson P, Veeramani S, Baragiotta A, Floreani A, Venturi C, Pearce S, Wilson V, Jones D, James O, Taylor J, Newton J, Bassendine M. . Clinical Gastroenterology and Hepatology 2007, 5(6), 755-760.
- Jones DEJ. . Journal of Hepatology 2007, 46(6), 992-994.
- Jones DEJ, Newton JL. . Gut 2007, 56, 1166.
- Newton JL, Hudson M, Tachtatzis P, Sutcliffe K, Pairman J, Burt JA, Jones DEJ. . Hepatology 2007, 45(6), 1496-1505.
- Blackburn P, Freeston M, Baker CR, Jones DEJ, Newton JL. . Liver International 2007, 27(5), 654-661.
- Linnett VC, Jones DEJ. . CPD Anaesthesia 2006, 8(2), 87-94.
- Newton JL, Jones DEJ, Wilton K, Pairman J, Parry SW, Francis RM. . QJM: An International Journal of Medicine 2006, 99(4), 231-236.
- Newton JL, Bhala N, Burt J, Jones DEJ. . Journal of Hepatology 2006, 44(4), 776-783.
- Newton JL, Gibson GJ, Tomlinson M, Wilton K, Jones D. . Hepatology 2006, 44(1), 91-98.
- Jones DEJ, Bhala N, Burt J, Goldblatt J, Prince M, Newton JL. . Gut 2006, 55(4), 536-541.
- Donaldson PT, Baragiotta A, Heneghan MA, Floreani A, Venturi C, Underhill JA, Jones DEJ, James OFW, Bassendine MF. . Hepatology 2006, 44(3), 667-674.
- McHugh A, Robe AJ, Palmer JM, Jones DEJ. . Liver International 2006, 26(4), 406-413.
- Jones DEJ, Newton JL. . Horizons in Medicine 2006, 17, 307-315.
- Newton JL, Allen J, Kerr S, Jones DEJ. . Liver International 2006, 26(2), 197-202.
- Jones DEJ, Bhala N, Newton JL. . Hepatology 2006, 43(3), 633.
- Broad A, Jones DEJ, Kirby JA. . Current Medicinal Chemistry 2006, 13(21), 2487-2502.
- Broad A, Kirby JA, Jones DEJ. . Immunology 2006, 120(1), 103-111.
- Robe AJ, Kirby JA, Jones DEJ, Palmer JM. . Hepatology 2005, 41(5), 1106-1112.
- Jacoby A, Rannard A, Buck D, Bhala N, Newton JL, James OFW, Jones DEJ. . Gut 2005, 54(11), 1622-1629.
- Rannard A, Buck D, Jones DEJ, James OFW, Jacoby A. . Clinical Gastroenterology and Hepatology 2004, 2(2), 164-174.
- Baragiotta A, Floreani A, Agarwal K, Venturi C, Craggs A, Jones DEJ, Donaldson PT, Bassendine MF. . Liver International 2004, 24(6), 646-650.
- Palmer JM, Robe AJ, Burt AD, Kirby JA, Jones DEJ. . Hepatology 2004, 39(6), 1583-1592.
- Forton DM, Patel N, Prince M, Oatridge A, Hamilton G, Goldblatt J, Allsop JM, Hajnal JV, Thomas HC, Bassendine M, Jones DEJ, Taylor-Robinson SD. . Gut 2004, 53(4), 587-592.
- Baragiotta A, Floreani A, Agarwal K, Venturi C, Craggs A, Jones DEJ, Donaldson PT, Bassendine MF. . Liver International 2004, 24(6), 646-650.
- Stewart SF, Vidali M, Day CP, Albano E, Jones DEJ. . Hepatology 2004, 39(1), 197-203.
- Jones DEJ. . Clinical Medicine 2003, 3(4), 351-356.
- Goldblatt J, Jones DEJ. . Gastroenterology 2003, 124(2), 582.
- Vidali M, Stewart SF, Rolla R, Daly AK, Chen Y, Mottaran E, Jones DEJ, Leathart JB, Day CP, Albano E. . Hepatology 2003, 37(2), 410-419.
- Jones DEJ, Donaldson PT. . Clinics in Liver Disease 2003, 7(4), 841-864.
- Prince MI, Mitchison H, Ashley D, Burke DA, Edwards N, Bramble M, James OFW, Jones DEJ. . Alimentary Pharmacology and Therapeutics 2003, 17(1), 137-143.
- McRae CA, Prince MI, Hudson M, Day CP, James OFW, Jones DEJ. . Gastroenterology 2003, 125(2), 591-596.
- Jones DEJ. . Journal of Hepatology 2003, 39(4), 639-648.
- Kirby JA, Bone M, Robertson H, Hudson M, Jones DEJ. . Journal of Clinical Pathology 2003, 56(2), 158-.
- Jones DEJ, Palmer JM, Burt AD, Walker C, Robe AJ, Kirby JA. . Hepatology 2002, 36(3), 679-686.
- Robe A, Palmer J, Kirby J, Jones D. . In: Journal of Hepatology. 2002, Elsevier BV.
- Jones DEJ. . Medicine 2002, 30(12), 67-68.
- Agarwal K, Jones DEJ, Burt AD, Hudson M, James OFW. . American Journal of Gastroenterology 2002, 97(3), 750-751.
- Jones DEJ, Palmer JM, Robe A, Kirby JA. . Autoimmunity 2002, 35(8), 537-544.
- Newton J, Jones D. . Panminerva Medica 2002, 44(4), 335-341.
- Newton JL, James OFW, Bassendine MF, Jones DEJ. . Gut 2002, 50, 898-899.
- Palmer JM, Kirby JA, Jones DEJ. . Clinical and Experimental Immunology 2002, 129(2), 191-197.
- Goldblatt J, Taylor PJS, Lipman T, Prince MI, Baragiotta A, Bassendine MF, James OFW, Jones DEJ. . Gastroenterology 2002, 122(5), 1235-1241.
- Stewart SF, Daly AK, Chen Y, Leathart JB, Jones DEJ, Rolla R, Vay D, Mottaran E, Vidali M, Albano E, Day CP. . Journal of Hepatology 2001, 34(1), 200.
- Stewart S, Jones D, Day CP. . Trends in Molecular Medicine 2001, 7(9), 408-413.
- Jones DEJ, Prince MI. Antioxidants and chronic liver disease. Nutrition Practitioner 2001, 3, 42-43.
- Jones DE, Robe AJ, Palmer JM, Kirby JA. Exploration of the immunogenicity of the primary biliary cirrhosis autoantigen pyuvate dehydrogenase complex. Hepatology 2001, 34, 730.
- Johns E, Goldblatt J, Jones DE, Newton JL. . In: Hepatology. 2001, John Wiley & Sons, Inc.
- Goldblatt J, James OFW, Jones DEJ. . Journal of the American Medical Association 2001, 285(17), 2196-2197.
- Donaldson P, Agarwal K, Craggs A, Craig W, James O, Jones D. . Gut 2001, 48(3), 397-402.
- Prince MI, Jones DEJ. . Current Opinion in Psychiatry 2001, 14(6), 585-590.
- Neill D, Hughes D, Leake A, Morris C, Jones D, Oakley A, Edwardson J, Estibeiro P. . Dementia and Geriatric Cognitive Disorders 2001, 12(1), 40-51.
- Newton J, Francis R, Prince M, James O, Bassendine M, Rawlings D, Jones D. . Gut 2001, 49(2), 282-287.
- Walter R, Agarwal K, Jackson R, Rose J, Hudson M, Jones DE. . In: Journal of Hepatology. 2001, Elsevier BV.
- Jones DEJ. . Journal of Clinical Pathology 2000, 53(11), 813-821.
- Yeamon SJ, Kirby JA, Jones DEJ. . Immunological Reviews 2000, 174(1), 238-249.
- Agarwal K, Czaja AJ, Jones DEJ, Donaldson PT. . Hepatology 2000, 31(1), 49-53.
- Agarwal K, Czaja AJ, Jones DEJ, Donaldson PT. . Hepatology 2000, 31(1), 49-53.
- Jones DE. . Journal of Hepatology 2000, 33(5), 834-837.
- Agarwal K, Jackson R, Rose J, Jones DE, James OF, Hudson M. PBC and portal hypertension: Is TIPS a successful bridge to transplant? A single centre retrospective review. In: HEPATOLOGY. 2000.
- Prince MI, Jones DEJ. . Postgraduate Medical Journal 2000, 76(894), 199-206.
- Jones DEJ. . Journal of the Royal College of Physicians (London) 2000, 34(3), 302-305.
- Palmer JM, Doshi M, Kirby JA, Yeaman SJ, Bassendine MF, Jones DEJ. . Clinical and Experimental Immunology 2000, 122(3), 423-428.
- Robe A, Palmer JM, Yeaman SJ, Jones DEJ. The E3BP (protein X) component of pyruvate dehydrogenase complex (PDC) is not a T-cell autoantigen in primary biliary cirrhosis (PBC). In: JOURNAL OF HEPATOLOGY. 2000.
- Prince MI, James OFW, Holland NP, Jones DEJ. . Journal of Hepatology 2000, 32(3), 368-373.
- Howel D, Metcalf JV, Gray J, Newman WL, Jones DEJ, James OFW. . Gut 1999, 45(5), 756-760.
- Watson JP, Jones DEJ, James OFW, Cann PA, Bramble MG. . Journal of Gastroenterology and Hepatology 1999, 14(10), 1034-1040.
- Palmer JM, Jones DEJ, Quinn J, McHugh A, Yeaman SJ. . Hepatology 1999, 30(1), 21-26.
- Jones DEJ, James OFW, Portmann B, Burt AD, Williams R, Hudson M. . Hepatology 1999, 30(1), 53-57.
- Jones DEJ, Watt FE, Metcalf JV, Bassendine MF, James OFW. . Journal of Hepatology 1999, 30(3), 402-407.
- Palmer JM, Diamond AG, Yeaman SJ, Bassendine MF, Jones DEJ. . Clinical and Experimental Immunology 1999, 116(1), 113-139.
- Prince MI, Osborne JS, Ingoe L, Jones DE, Cobden I, Barton JR. . European Journal of Gastroenterology and Hepatology 1999, 11(11), 1251-1254.
- Agarwal K, Jones DEJ. . British Medical Journal 1999, 319(7207), 450-451.
- Jones DEJ, Watt FE, Grove J, Newton JL, Daly AK, Gregory WL, Day CP, James OFW, Bassendine MF. . Journal of Hepatology 1999, 30(2), 232-236.
- Zappala F, Grove J, Watt FE, Daly AK, Day CP, Bassendine MF, Jones DEJ. No evidence for involvement of the interleukin-10 -592 promoter polymorphism in genetic susceptibility to primary biliary cirrhosis. Journal of Hepatology 1998, 28, 820-823.
- Jones DEJ, Barton J, Cobden I. Painless small bowel ischemia presenting with diarrhoea and weight loss. American Journal of Gastroenterology 1998, 93, 653-655.
- Jones DEJ, James OFW, Bassendine MF. . Clinics in Liver Disease 1998, 2(2), 265-282.
- Jones DEJ, Metcalf JV, Collier JD, Bassendine MF, James OFW. Hepatocellular carcinoma in primary biliary cirrhosis and its impact on outcomes. Hepatology 1997, 26, 1138-42.
- Jones DEJ, Yeaman SJ, Diamond AG, Bassendine MF. T-cell responses to Tuberculin-purified protein derivative in primary biliary cirrhosis: evidence for defective T-cell function. Gut 1997, 40, 277-283.
- Jones DEJ. T-cell autoimmunity in primary biliary cirrhosis. Clinical Science 1996, 91, 551-558.