Staff Profile
Dr Fraser Birrell
Honorary Clinical Senior Lecturer
- Email: fraser.birrell@ncl.ac.uk
- Telephone: +44 (0) 191 208 5548
- Fax: +44 (0) 191 208 5455
- Personal Website:
- Address: Institute of Cellular Medicine
Musculoskeletal Research Group
4th Floor Catherine Cookson Building
The Medical School
Framlington Place
缅北禁地
NE2 4HH
Title of current
posts
- Consultant & Senior Lecturer in Rheumatology, Northumbria Healthcare NHS Foundation Trust
- Honorary Clinical Senior Lecturer, 缅北禁地
- Honorary Consultant Rheumatologist, 缅北禁地 Hospitals NHS Foundation Trust All May 2002-
Area of expertise:
Translational Epidemiology
Osteoarthritis- biomarkers and treatment
Musculoskeletal Ageing
Group Consultations (aka Group Clinics; Academic Lead of Shared Medical Appointments UK)
Patient Engagement (Engagement Lead for CIMA)
Funding
My role is 6 sessions clinical, 3 sessions undergraduate teaching (SIFT), 2 sessions postgraduate teaching & research (Degree Programme Director Masters of Clinical Research) & 0.5 session CLRN. There is agreement through the PDR process & appraisal to increase research time. I am both clinically qualified and clinically active.
Employment History
Specialist Registrar to: Dr PA Sanders, Dr B Pal & Dr A Ismail, Rheumatology,
South Manchester University Hospitals
Honorary Clinical Research Fellow, arc Epidemiology Unit (now ARUK) Aug 2001-April 2002
Specialist Registrar to: Dr RM Bernstein & Dr I Bruce, Rheumatology, Manchester Royal Infirmary
Honorary Clinical Research Fellow, arc Epidemiology Unit (now ARUK) Feb 2000-July 2001
Clinical Epidemiology Training Fellow: Professor AJ Silman (supervisor) & Dr GJ Macfarlane (adviser)
arc Epidemiology Unit, University of Manchester (now ARUK) Feb 1997-Jan 2000
Registrar to: Dr RC Butler & Dr AF Macleod, Rheumatology & General Medicine/Endocrinology, Royal Shrewsbury Hospital, Robert Jones & Agnes Hunt Orthopaedic Hospital, Oswestry Feb 1996-Jan 1997
Registrar to: Dr T Price, Dr TP Sheeran & Dr AB Hassell, Dr J Gibson, Dr J Elizabeth
Rheumatology & General/Elderly Medicine, Cannock Chase Hospital Feb 1995-Jan 1996
Senior House Officer to: Prof. J Walls, Dr J Feehally, Dr K Harris & Dr G Warwick
Nephrology, Leicester General Hospital Aug 1994-Jan 1995
Senior House Officer to: Prof. DB Barnett, Dr KL Woods & Dr LL Ng
Clinical Pharmacology & Medicine, Leicester Royal Infirmary Feb-July 1994
Senior House Officer to: Prof. David de Bono & Dr PJB Hubner
Cardiology, Groby Road Hospital & Glenfield General Hospital Aug 1993-Jan 1994
Senior House Officer to: Dr DR Ives, Medicine for the Elderly, Leicester Royal Infirmary May-July 1993
Senior House Officer to: Dr MA Stern & Dr A Scriven. Medicine, Immunology & Cardiology,
Leicester General Hospital Feb-April 1993
Pre-registration House Surgeon to: Mr DNL Ralphs, Mr BA Ross & Mr R Vaughan.
General & Thoracic Surgery, Norfolk & Norwich Hospital Aug 1992-Jan 1993
Pre-registration House Physician to: Dr G Neale, Dr JO Hunter Dr BL Hazleman, Dr AJ Crisp & Dr JR Jenner, Medicine, Gastroenterology & Rheumatology, Addenbrooke’s Hospital Feb-July 1992
Education
Secondary: The Manchester Grammar School 1979-
Undergraduate: Emmanuel College, Cambridge 1986-
Clinical School: Addenbrooke’s, Cambridge 1989-
Leicester SHO Rotation in Medicine 1993-
North Midlands Specialist Registrar Rotation in Rheumatology 1995-
PhD: ARUK Epidemiology Unit, University of Manchester 1997-
North West Specialist Registrar Rotation in Rheumatology 2000-2
Postgraduate Certificate & Diploma in Clinical Education 2004-9
Qualifications:
BA (Hon’s, Med Sci Tripos, Cantab. IIi) Part II Physiology 1989
MB, B Chir (Cantab.) 1991
MA (Hon’s, Cantab.) 1993
MRCP (UK) 1994
FRCP (RCP London) 2007
PhD (Manchester) 2000
Certificate & Diploma of Clinical Education (缅北禁地) ,2004 & 2009
Senior Fellowship of the Higher Education Academy 2018
Prizes
- LEA Scholarship to Manchester Grammar School
- Junior & Senior Exhibitions, Emmanuel College
- Fisons Prize, Paed’s Dept, Addenbrooke’s (for paper on Cystic Fibrosis)
- Desmond Hawkins Award, University of Cambridge
- Commonwealth Foundation Elective Bursary
- 3M Elective Competition, First prize (Cambridge)
- Leicester Hospitals Case Presentation Competition, First Prize
- (for presentation on Wegener’s granulomatosis)
- arc/ARUK Clinical Epidemiology Training Fellowship
- British Society for Rheumatology Young Investigator Award
(for research on progression of hip osteoarthritis) - BSR Innovation in Development Award (for Group Clinic pilot)
My research students have also been awarded:
- British Society for Rheumatology Young Investigator; OARSI Young Investigator; DOHAD Young Investigator; EULAR bursary; ARUK Primary Care regional & national prizes; Zeshan-Qureshi Award for Outstanding Achievement in Medical Education
Recent & Current Grants
PROvision of braces for Patients with knee OsteoArthritis (PROP OA): a randomised controlled trial
National Institute for Health Research Health Technology Assessment Commissioned Call: 16/160 Knee Braces in the Management of Knee Osteoarthritis
01/09/18-30/08/22
Co-applicant & Principal Investigator for Northumbria Site (1 of 3 sites; CI: Prof George Peat, Keele)
£1,377,543
Are microRNAs a molecular clock for biological and musculoskeletal ageing? The 缅北禁地 Thousand Families Study (NTFS)
National Institute for Health Research 缅北禁地 Biomedical Research Centre Project Grant
05/02/18-04/08/19
Principal Investigator
£60,824.87
Industry Partnership HTG
Loan equipment provided by HTG (equipment value £120,000)
Partnership discount saving on Edgeseq analysis= £750-£125=£625 per sample (for 390 samples) = £243,750
Training & support £10,000
Group Consultations; a potential solution to the workforce crisis in primary care.
Health Education England NE
1/11/17-31/10/18
Joint Principal Investigator
£49,500
Centre for Integrated research into Musculoskeletal Ageing (CIMA) Renewal
Medical Research Council & Arthritis Research UK
01/06/17-31/05/22
Co-investigator: Engagement Lead
£1,999,998.00 (FEC £2.45m)
CIMA equipment award (Qubit™ fluorometric quantitation)
Medical Research Council & Arthritis Research UK
Co-investigator (with Tania Jones & David Young)
12/12/16
£2,515.20
PROMOTE: a trial to treat painful knee osteoarthritis
Arthritis Research UK
Principal Investigator for multicentre study (Philip Conaghan CI)
01/10/2012-30/9/2018
£1,200,471.90
HERO: does hydroxychloroquine provide effective pain relief for people with hand osteoarthritis?
Arthritis Research UK
Principal Investigator for multicentre study
01/09/2011-31/8/2015
£900,692.45
Arthritis Research UK Experimental Arthritis Treatment Centre- 缅北禁地
Arthritis Research UK
Co-Investigator
01/07/2012-30/06/2018
£375,000.00
CIMA Clinical Fellowship: Lifecourse influences on the development of structural changes on pMRI
Arthritis Research UK & Medical Research Council
Chief Investigator
01/09/2014-31/8/2015
£35,592.00
A pilot study to investigate the role of CILP in predicting the development of Osteoarthritis
NIHR BRC for Ageing
Collaborator
01/07/2014-30/06/2015
£21,158.34
X-ray Reconstruction of Moving Morphology (XROMM) for human and veterinary biomechanics
Medical Research Council
Co-Investigator (Lead for 缅北禁地; Karl Bates CI)
September 2013
£657,000
- Luqmani R, Hennell S, Estrach C, Birrell F, Bosworth A, Davenport G, Fokke C, Goodson N, Jeffreson P, Lamb E, Mohammed R, Oliver S, Stableford Z, Walsh D, Washbrook C, Webb F, British Society for Rheumatology, British Health Professionals in Rheumatology Standards, Guidelines and Audit Working Group. . Rheumatology 2006, 45(9), 1167-1169.
- Birrell F, Lohmander S. . British Medical Journal 2006, 333(7567), 507-508.
- Roddy E, Zhang W, Doherty M, Arden NK, Barlow J, Birrell F, Carr A, Chakravarty K, Dickson J, Hay E, Hosie G, Hurley M, Jordan KM, McCarthy C, McMurdo M, Mockett S, O'Reilly S, Peat G, Pendleton A, Richards S. . Journal of Evaluation in Clinical Practice 2006, 12(3), 347-52.
- Pearce MS, Birrell F, Francis RM, Rawlings DJ, Tuck SP, Parker L. . Journal of Epidemiology and Community Health 2005, 59(6), 475-480.
- Birrell F, Lunt M, Macfarlane G, Silman A. . Rheumatology 2005, 44(3), 337-341.
- Birrell F, Lunt M, Macfarlane GJ, Silman AJ. . Annals of the Rheumatic Diseases 2005, 64(1), 95-98.
- Tuck SP, Pearce MS, Rawlings DJ, Birrell FN, Parker L, Francis RM. . British Journal of Radiology 2005, 78(930), 493-498.
- Roddy E, Zhang W, Doherty M, Arden NK, Barlow J, Birrell F, Carr A, Chakravarty K, Dickson J, Hay E, Hosie G, Hurley M, Jordan KM, McCarthy C, McMurdo M, Mockett S, O'Reilly S, Peat G, Pendleton A, Richards S. . Rheumatology 2005, 44(1), 67-73.
- Birrell F, Arden NK, Conaghan PG, Cooper C, Dieppe P, Doherty M. . Rheumatology 2005, 44(7), 829-830.
- Birrell F, Pearce MS, Francis RM, Parker L. . Clinical Rheumatology 2005, 24(6), 590-592.
- Birrell FN. . Rheumatology 2004, 43(4), 408-409.
- Pope DP, Hunt IM, Birrell FN, Silman AJ, Macfarlane GJ. . Annals of the Rheumatic Diseases 2003, 62(4), 322-326.
- Birrell F, Croft P, Cooper C, Hosie G, Macfarlane G, Silman A. . Annals of the Rheumatic Diseases 2003, 62(4), 356-358.
- Birrell FN, Gordon F. . BMJ careers 2001, 322(7286), S2.
- Birrell F, Croft P, Cooper C, Hosie G, Macfarlane G, Silman A. . Rheumatology 2001, 40(5), 506-512.
- Birrell F, Croft P, Cooper C, Hosie G, Macfarlane G, Silman A. . Annals of the Rheumatic Diseases 2000, 59(11), 857-863.
- Birrell FN, Hassell AB, Jones PW, Dawes PT. How Does the Short Form 36 Health Questionnaire (SF-36) in Rheumatoid Arthritis (RA) Relate to RA Outcome Measures and SF-36 Population Values? A Cross-sectional Study. Clin Rheumatol 2000, 19, 195-99.
- Birrell F, Croft P, Cooper C, Hosie G, Macfarlane GJ, Silman A. . Rheumatology 2000, 39(7), 772-725.
- Birrell F, Johnell O, Silman A. . Annals of the Rheumatic Diseases 1999, 58, 569-572.
- Kingsbury SR, Tharmanathan P, Keding A, Ronaldson S, Grainger A, Wakefield R, Arundel C, Birrell F, Doherty M, Vincent T, Watt FE, Dziedzic K, O'Neill T, Arden N, Scott DL, Dickson J, Garrood T, Green M, Menon A, Sheeran T, Torgerson D, Conaghan PG. . Osteoarthritis and Cartilage 2017, 25(12), 2147-2147.
- Hind K, Pearce M, Birrell F. . Journal of Bone and Mineral Research 2017, 32(5), 1109-1115.
- Ahmed HE, Pearce MS, Birrell F. . In: 2016 OARSI World Congress on Osteoarthritis - Promoting Clinical and Basic Research in Osteoarthritis. 2016, Amsterdam, Netherlands: Elsevier.
- Jones O, Birrell F. . Practitioner 2016, 260(1799), 13-16.
- Kingsbury SR, Corp N, Watt FE, Felson DT, O'Neill TW, Holt CA, Jones RK, Conaghan PG, Arden NK, Adams J, Appleyard I, Birrell F, Blank M, Callaghan MJ, Cumming J, Chapman GJ, Halstead J, Hamilton DF, Hurley M, Martin K, Mason DJ, Nuki G, Redmond AC, Reilly K, Robinson N, Roddy E, Simpson H, Smith TO, Thomas C, Thomas E, Wilkinson J, Wise E. . Rheumatology (United Kingdom) 2016, 55(8), 1394-1402.
- Duncan R, Kingston A, Stephan B, Birrell F, Kirkwood T, Jagger C. . In: Rheumatology 2016. 2016, Glasgow: Oxford University Press.
- Roberts E, Nunes VD, Buckner S, Latchem S, Constanti M, Miller P, Doherty M, Zhang WY, Birrell F, Porcheret M, Dziedzic K, Bernstein I, Wise E, Conaghan PG. . Annals of the Rheumatic Diseases 2016, 75(3), 552-559.
- Arden NK, Cro S, Sheard S, Dore CJ, Bara A, Tebbs SA, Hunter DJ, James S, Cooper C, O'Neill TW, Macgregor A, Birrell F, Keen R. . Osteoarthritis and Cartilage 2016, 24(11), 1858-1866.
- van Middelkoop M, Arden NK, Atchia I, Birrell F, Chao J, Rezende MU, Lambert RGW, Ravaud P, Bijlsma JW, Doherty M, Dziedzic KS, Lohmander LS, McAlindon TE, Zhang W, Bierma-Zeinstra SMA. . Osteoarthritis and Cartilage 2016, 24(7), 1143-1152.
- Conaghan PG, Porcheret M, Kingsbury SR, Gammon A, Soni A, Hurley M, Rayman MP, Barlow J, Hull RG, Cumming J, Llewelyn K, Moscogiuri F, Lyons J, Birrell F. . Clinical Rheumatology 2015, 34(9), 1581-1588.
- Duncan R, Francis RM, Jagger C, Kingston A, McCloskey E, Collerton J, Robinson L, Kirkwood TBL, Birrell F. . Osteoporosis International 2015, 26(1), 123-130.
- Duncan R, Francis RM, Jagger C, Kingston A, McCloskey E, Collerton J, Robinson L, Kirkwood TBL, Birrell F. . Osteoporosis International 2015, 26(1), 123-130.
- Kingsbury SR, Tharmanathan P, Arden NK, Batley M, Birrell F, Cocks K, Doherty M, Edwards CJ, Garrood T, Grainger AJ, Green M, Hewitt C, Hughes R, Moots R, O'Neill TW, Roddy E, Scott DL, Watt FE, Torgerson DJ, Conaghan PG. . Trials 2015, 16, 77.
- Felson DT, Redmond AC, Chapman GJ, Smith TO, Hamilton DF, Jones RK, Holt CA, Callaghan MJ, Mason DJ, Conaghan PG, Adams J, Arden NK, Birrell F, Cumming J, Corp N, Halstead J, Hurley M, Kingsbury SR, Martin K, Nuki G, O'Neill T, Reilly K, Robinson N, Roddy E, Simpson H, Thomas C, Thomas E, Watt FE, Wilkinson J, Wise E. . Rheumatology (United Kingdom) 2015, 55(2), 320-326.
- Scott DL, Ibrahim F, Farewell V, O'Keeffe AG, Walker D, Kelly C, Birrell F, Chakravarty K, Maddison P, Heslin M, Patel A, Kingsley GH. . BMJ 2015, 350, h1046.
- Evangelou E, Kerkhof HJ, Styrkarsdottir U, Ntzani EE, Bos SD, Esko T, Evans DS, Metrustry S, Panoutsopoulou K, Ramos YFM, Thorleifsson G, Tsilidis KK, arcOGEN Consortium, Arden N, Aslam N, Bellamy N, Birrell F, Blanco FJ, Carr A, Chapman K, Day-Williams AG, Deloukas P, Doherty M, Engstrom G, Helgadottir HT, Hofman A, Ingvarsson T, Jonsson H, Keis A, Keurentjes JC, Kloppenburg M, Lind PA, McCaskie A, Martin NG, Milani L, Montgomery GW, Nelissen RGHH, Nevitt MC, Nilsson PM, Ollier WER, Parimi N, Rai A, Ralston SH, Reed MR, Riancho JA, Rivadeneira F, Rodriguez-Fontenla C, Southam L, Thorsteinsdottir U, Tsezou A, Wallis GA, Wilkinson JM, Gonzalez A, Lane NE, Lohmander LS, Loughlin J, Metspalu A, Uitterlinden AG, Jonsdottir I, Stefansson K, Slagboom PE, Zeggini E, Meulenbelt I, Ioannidis JPA, Spector TD, van Meurs JBJ, Valdes AM. . Annals of the Rheumatic Diseases 2014, 73(12), 2130-2136.
- Abraham AM, Pearce MS, Mann KD, Francis RM, Birrell F. . BMC Musculoskeletal Disorders 2014, 15, 162.
- Hind K, Birrell F, Beck B. . PLoS One 2014, 9(5), e97427.
- Stamm T, Hieblinger R, Bostrom C, Mihai C, Birrell F, Thorstensson C, Fialka-Moser V, Meriaux-Kratochvila S, Smolen J, Coenen M. . Musculoskeletal Care 2014, 12(1), 22-33.
- van Middelkoop M, Arden N, Atchia I, Birrell F, Chao J, Lambert RG, Ravaud P, Bijlsma JJ, Doherty M, Dziedzic KS, Lohmander S, McAlindon TE, Zhang W, Bierma-Zeinstra SM. . In: 2014 World Congress on Osteoarthritis. 2014, Paris, France: Elsevier.
- Hind K, Birrell F, Beck B. . In: 61st Annual Meeting of American College of Sports Medicine. 2014, Florida, USA: Lippincott Williams & Wilkins.
- Hudson G, Panoutsopoulou K, Wilson I, Southam L, Rayner NW, Arden N, Birrell F, Carluke I, Carr A, Chapman K, Deloukas P, Doherty M, McCaskie A, Ollier WE, Ralston SH, Reed MR, Spector TD, Valdes AM, Wallis GA, Wilkinson JM, Zeggini E, Samuels DC, Loughlin J, Chinnery PF. . Annals of Rheumatic Diseases 2013, 72(1), 136-139.
- Abraham A, Pearce MS, Mann KD, Francis RM, Birrell F. . In: Annual Meeting of the British Society for Rheumatology. 2012, Glasgow, UK: Oxford University Press.
- Abraham A, Pearce MS, Mann KD, Francis RM, Birrell F. . In: Annual Meeting of the British Society for Rheumatology. 2012, Glasgow, UK: Oxford University Press.
- Abraham AM, Pearce MS, Mann KD, Francis RM, Birrell F. . In: Annual Meeting of the British Society for Rheumatology. 2012, Glasgow, UK: Oxford University Press.
- Abraham A, Mann KD, Pearce MS, Francis RM, Birrell F. . In: Annual European Congress of Rheumatology EULAR. 2012, Berlin, Germany: BMJ Publishing Group.
- Nicolaou M, Amstrong R, Hassell AB, Walker D, Birrell F. . In: Rheumatology: Annual Meeting of the British Society for Rheumatology. 2011, Brighton, UK: Oxford University Press.
- Abraham A, Mann KD, Pearce MS, Francis RM, Birrell F. . In: Journal of Developmental Origins of Health and Disease: 7th World Congress on Developmental Origins of Health and Disease. 2011, Portland, Oregon, USA: Cambridge University Press.
- Duncan R, Francis RM, Collerton J, Davies K, Jagger C, Kingston A, Kirkwood T, Robinson L, Birrell F. . In: Age and Ageing: British Geriatrics Society Spring Meeting. 2011, Liverpool: Oxford University Press.
- Duncan R, Francis RM, Collerton J, Davies K, Jagger C, Kingston A, Kirkwood T, Robinson L, Birrell F. . Age and Ageing 2011, 40(6), 752-755.
- Abraham A, Pearce MS, Francis RM, Birrell F. . In: Rheumatology: Annual Meeting of the British Society for Rheumatology. 2011, Brighton, UK: Oxford University Press.
- Abraham AM, Goff I, Pearce MS, Francis RM, Birrell F. . BMC Musculoskeletal Disorders 2011, 12(1), 70.
- Atchia I, Kane D, Reed MR, Isaacs J, Birrell F. . In: Rheumatology: Annual Meeting of the British Society of Rheumatology. 2009, Glasgow, UK: Oxford University Press.
- Birrell F, Croft P, Cooper C, Hosie G, Macfarlane G, Silman A. . British Journal of General Practice 2003, 53(486), 26-30.