缅北禁地

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Staff Profile

Dr Helen Tuppen

Senior Research Associate

  • Telephone: +44 (0) 191 208 3098
  • Address: Mitochondrial Research Group
    缅北禁地
    Medical School
    Framlington Place
    缅北禁地 upon Tyne
    NE2 4HH
    UK
Publications

  • Articles

    • Stephenson EJ, Bailey LJ, Gentleman S, Tuppen H, Bodi I, Troakes C, Morris CM, Carr TM, Guthrie S, Elson JL, Pienaar IS. . Aging Cell 2025, 24(8), e70125.
    • Faitg J, Davey T, Laws R, Lawless C, Tuppen H, Fitton E, Turnbull D, Vincent AE. . Communications Biology 2025, 8, 24.
    • McDonald C, Alderson C, Birkbeck MG, Del Din S, Gorman GS, Hollingsworth KG, Kirk C, Massarella C, Rochester L, Tuppen HAL, Warren C, Sayer AA, Witham MD. . GeroScience 2025, 47, 6065-6078.
    • Hipps D, Pyle A, Porter ALR, Dobson PF, Tuppen H, Lawless C, Russell OM, Turnbull DM, Deehan DJ, Hudson G. . Scientific Reports 2024, 14(1), 20989.
    • McDonald C, Alderson C, Birkbeck MG, Brown L, Del Din S, Gorman G, Hollingsworth KG, Massarella C, Rehman R, Rochester L, Sayer AA, Su H, Tuppen HAL, Warren C, Witham MD. . BMJ Open 2024, 14, e076518.
    • Abouhajar A, Alcock L, Bigirumurame T, Bradley P, Brown L, Campbell I, Del Din S, Faitg J, Falkous G, Gorman GS, Lakey R, McFarland R, Newman J, Rochester L, Ryan V, Smith H, Steel A, Stefanetti RJ, Su H, Taylor RW, Thomas NJP, Tuppen H, Vincent AE, Warren C, Watson G. . Trials 2022, 23(1), 789.
    • Lehmann D, Tuppen HAL, Campbell G, Alston CL, Lawless C, Rosa HS, Rocha MC, Reeve AK, Nicholls TJ, Deschauer M, Zierz S, Taylor RW, Turnbull DM, Vincent AE. . Nucleic Acids Research 2019, 47(14), 7430–7443.
    • Rocha MC, Rosa HS, Grady JP, Blakely EL, He L, Romain N, Haller RG, Newman J, McFarland R, Ng YS, Gorman GS, Schaefer AM, Tuppen HA, Taylor RW, Turnbull DM. . Annals of Neurology 2018, 83(1), 115-130.
    • Hyslop LA, Blakeley P, Craven L, Richardson J, Fogarty NME, Fragouli E, Lamb M, Wamaitha SE, Prathalingam N, Zhang Q, O'Keefe H, Takeda Y, Arizzi L, Alfarawati S, Tuppen H, Irving L, Kalleas D, Choudhary M, Wells D, Murdoch AP, Turnbull DM, Niakan KK, Herbert M. . Nature 2016, 534(7607), 383-386.
    • Perli E, Fiorillo A, Giordano C, Pisano A, Montanari A, Grazioli P, Campese AF, Di Micco P, Tuppen HA, Genovese I, Poser E, Preziuso C, Taylor RW, Morea V, Colotti G, d'Amati G. . Human Molecular Genetics 2016, 25(5), 903-915.
    • Rygiel KA, Tuppen HA, Grady JP, Vincent A, Blakely EL, Reeve AK, Taylor RW, Picard M, Miller J, Turnbull DM. . Nucleic Acids Research 2016, 44(11), 5313-5329.
    • Rygiel KA, Grady JP, Taylor RW, Tuppen HAL, Turnbull DM. . Scientific Reports 2015, 5, 9906.
    • Lehmann D, Schubert K, Joshi PR, Hardy SA, Tuppen HAL, Baty K, Blakely EL, Bamberg C, Zierz S, Deschauer M, Taylor RW. . European Journal of Human Genetics 2015, 23(12), 1735-1738.
    • Gorman GS, Blakely EL, Hornig-Do HT, Tuppen HAL, Greaves LC, He LP, Baker A, Falkous G, Newman J, Trenell MI, Lecky B, Petty RK, Turnbull DM, McFarland R, Taylor RW. . Clinical Science 2015, 128(12), 895-904.
    • McCann BJ, Tuppen HAL, Kusters B, Lammens M, Smeitink JAM, Taylor RW, Rodenburg RJ, Wortmann SB. . Neuromuscular Disorders 2015, 25(3), 262-267.
    • Greggains GD, Lister LM, Tuppen HAL, Zhang Q, Needham LH, Prathalingam N, Hyslop LA, Craven L, Polanski Z, Murdoch AP, Turnbull DM, Herbert M. . Scientific Reports 2014, 4, 3844.
    • Perli E, Giordano C, Pisano A, Montanari A, Campese AF, Reyes A, Ghezzi D, Nasca A, Tuppen HA, Orlandi M, Di Micco P, Poser E, Taylor RW, Colotti G, Francisci S, Morea V, Frontali L, Zeviani M, d'Amati G. . EMBO Molecular Medicine 2014, 6(2), 169-182.
    • Hornig-Do H-T, Montanari A, Rozanska A, Tuppen HA, Almalki AA, Abg-Kamaludin DP, Frontali L, Francisci S, Lightowlers RN, Chrzanowska-Lightowlers ZM. . EMBO Molecular Medicine 2014, 6(2), 183-193.
    • Greaves LC, Nooteboom M, Elson JL, Tuppen HAL, Taylor GA, Commane DM, Arasaradnam RP, Khrapko K, Taylor RW, Kirkwood TBL, Mathers JC, Turnbull DM. . PLoS Genetics 2014, 10(9), e1004620.
    • Grady JP, Murphy JL, Blakely EL, Haller RG, Taylor RW, Turnbull DM, Tuppen HAL. . PLoS One 2014, 9(12), e114462.
    • Giordano C, Perli E, Orlandi M, Pisano A, Tuppen HA, He L, Ierino R, Petruzziello L, Terzi A, Autore C, Petrozza V, Gallo P, Taylor RW, d'Amati G. . Human Pathology 2013, 44(7), 1262-1270.
    • Tuppen HA, Naess K, Kennaway NG, Al-Dosary M, Lesko N, Yarham JW, Bruhn H, Wibom R, Nennesmo I, Weleber RG, Blakely EL, Taylor RW, McFarland R. . European Journal of Human Genetics 2012, 20, 897-904.
    • Perli E, Giordano C, Tuppen HAL, Montopoli M, Montanari A, Orlandi M, Pisano A, Catanzaro D, Caparrotta L, Musumeci B, Autore C, Morea V, Di Micco P, Campese AF, Leopizzi M, Gallo P, Francisci S, Frontali L, Taylor RW, d'Amati G. . Human Molecular Genetics 2012, 21(1), 85-100.
    • Kemp JP, Smith PM, Pyle A, Neeve VCM, Tuppen HAL, Schara U, Talim B, Topaloglu H, Holinski-Feder E, Abicht A, Czermin B, Lochmuller H, McFarland R, Chinnery PF, Chrzanowska-Lightowlers ZM, Lightowlers RN, Taylor RW, Horvath R. . Brain 2011, 134(1), 183-195.
    • Tuppen HA, Hogan VE, He L, Blakely EL, Worgan L, Al-Dosary M, Saretzki G, Alston CL, Morris AA, Clarke M, Jones S, Devlin AM, Mansour S, Chrzanowska-Lightowlers ZMA, Thorburn DR, McFarland R, Taylor RW. . Brain 2010, 133(10), 2952-2963.
    • Craven L, Tuppen HA, Greggains GD, Harbottle SJ, Murphy JL, Cree LM, Murdoch AP, Chinnery PF, Taylor RW, Lightowlers RN, Herbert M, Turnbull DM. . Nature 2010, 465(7294), 82-85.
    • Tuppen HAL, Fehmi J, Czermin B, Goffrini P, Meloni F, Ferrero I, He LP, Blakely EL, McFarland R, Horvath R, Turnbull DM, Taylor RW. . Molecular Genetics and Metabolism 2010, 100(4), 345-348.
    • Horvath R, Kemp JP, Tuppen HAL, Hudson G, Oldfors A, Marie SKN, Moslemi AR, Servidei S, Holme E, Shanske S, Kollberg G, Jayakar P, Pyle A, Marks HM, Holinski-Feder E, Scavina M, Walter MC, Coku J, Gunther-Scholz A, Smith PM, McFarland R, Chrzanowska-Lightowlers ZMA, Lightowlers RN, Hirano M, Lochmuller H, Taylor RW, Chinnery PF, Tulinius M, DiMauro S. . Brain 2009, 132(11), 3165-3174.
    • Rorbach J, Yusoff A, Tuppen H, Abg-Kamaludin D, Chrzanowska-Lightowlers Z, Taylor R, Turnbull D, Mcfarland R, Lightowlers R. . Nucleic Acids Research 2008, 36(9), 3065-3074.
    • Tuppen HAL, Fattori F, Carrozzo R, Zeviani M, DiMauro S, Seneca S, Martindale JE, Olpin SE, Treacy EP, McFarland R, Santorelli FM, Taylor RW. . Journal of Medical Genetics 2008, 45(1), 55-61.
    • McFarland R, Chinnery PF, Blakely EL, Schaefer AM, Morris AAM, Foster SM, Tuppen HAL, Ramesh V, Dorman PJ, Turnbull DM, Taylor RW. . Neurology 2007, 69(9), 911-916.

  • Book Chapter

    • Tuppen HAL, Reeve AK, Vincent AE. . In: Mitochondrial DNA : Methods and Protocols. New York: Humana Press, Inc, 2023, pp.443-463.

  • Conference Proceedings (inc. Abstracts)

    • Williamson SC, Wilson L, Williamson GA, Greaves L, Tuppen H, Pickard R, Wright NA, Robson CN, Turnbull DM, Taylor RW, Heer R. . In: Annual Meeting of the Society-of-Academic-and-Research-Surgery. 2014, Univ Cambridge, Robinson Coll, Cambridge, ENGLAND: John Wiley & Sons Ltd.
    • Tuppen HAL, Fehmi J, Czermin B, Goffrini P, Meloni F, Ferreio I, He L, Blakely EL, McFarland R, Horvath R, Turnbull DM, Taylor RW. . In: Neuromuscular Disorders: 15th International Congress of the World Muscle Society. 2010, Kumamoto, Japan: Elsevier Ltd.
    • Horvath R, Kemp JP, Tuppen HAL, Hudson G, Pyle A, Holinski-Feder E, Abicht A, Czermin B, Walter MC, Gunther-Scholz A, Smith PM, McFarland R, Chrzanowska-Lightowlers ZMA, Lightowlers RN, Lochmuller H, Taylor RW, Chinnery PF. . In: United Kingdom Neuromuscular Translational Research Conference. 2010, Oxford, UK: Neuromuscular Disorders, Elsevier.
    • Wright KP, Tuppen HAL, Blakely EL, McFarland R, Brown GK, Taylor RW, Morris AAM. . In: Molecular Genetics and Metabolism: 11th International Conference of Inborn Errors of Metabolism. 2009, San Diego, CA, USA: Academic Press.
    • McFarland R, Tuppen H, He L, Blakely EL, Morris AAM, Clarke M, Jones S, Devlin AM, Taylor RW. . In: Neuromuscular Disorders: 14th International Congress of the World Muscle Society. 2009, Geneva, Switzerland: Elsevier Ltd.

  • Reviews

    • Keogh MJ, Chinnery PF. . Biochimica et Biophysica Acta (BBA) - Bioenergetics 2015, 1847(11), 1401-1411.
    • Craven L, Elson JL, Irving L, Tuppen HA, Lister LM, Greggains GD, Byerley S, Murdoch AP, Herbert M, Turnbull D. . Human Molecular Genetics 2011, 20(R2), R168-R174.
    • Tuppen HAL, Blakely EL, Turnbull DM, Taylor RW. . Biochimica et Biophysica Acta: Bioenergetics 2010, 1797(2), 113-128.