缅北禁地

Positions

• Professor of Molecular Microbiology (since 2024)
• Molecular and Cellular Microbiology theme lead (since 2023)
• Senior Lecturer (2019-2024)
• Independent Research Fellow and Group Leader, 缅北禁地 (2014-2019)
• Research Associate, 缅北禁地, Group of Prof Leendert Hamoen (2007-2014)
• PhD student, University of Osnabrück, Group of Prof Karlheinz Altendorf (2003-2007)

 Education

• Dr. rer. nat. Microbiology, University of Osnabrück, Germany (2003-2007)
• Dipl. Biology, University of Osnabrück, Germany (1997-2003)

Honors and Awards

BBSRC New Investigator Award (2018)

Editorial Board, Microbiology (2018-2025)

缅北禁地 Research Fellowship (2015)

Faculty of Medical Sciences Research Fellowship (2014)

Boehringer Ingelheim Fonds PhD Fellowship (2004)

Research

The research in my group focuses on bacterial cell envelopes and bioenergetics using model organisms such as Bacillus subtilis, Escherichia coli, and Staphylococcus aureus. Using a combination of cell biology, high-end fluorescence microscopy, genetics, and biochemistry, we investigate the function, synthesis and internal organisation of bacterial cell walls and membranes. Moreover, we study how cells maintain membrane integrity, respiration and efficient bioenergetic coupling under optimal growth conditions and upon stress. These more fundamental research lines are complemented by applied research aimed at understanding the complex mode of action of cell envelope-targeting antimicrobials and toxins, why certain cellular targets are less vulnerable to rapid development of antibiotic resistance, and at discovering new envelope-targeting antibiotics.

Current co-workers

Dr. Jess Buttress (post doc, BBSRC-funded)

Dr. Matthieu Blandenet (post doc, BBSRC-funded)

Dr. Rachel Darnell (post doc, BBSRC-funded)

Emily Dunbar (research assistant, BBSRC-funded)

Taylor Wellfare Reid (PhD student, MRC-funded)

Neha Ramchandani Ramchandani (PhD student, BBSRC-funded)

Amandeep Kaur (technician, BBSRC-funded)

Josh Drake (MRes student)

Abril Zaragoza Panisello (MSci student)

Funding

Biotechnology and Biological Sciences Research Council (BBSRC), Medical Research Council (MRC), Natural Environment Research Council (NERC)

Alumni

Post docs:

Dr. Alan Koh

PhD students:

Dr. Laura Dobby

Dr. Maria Dakes Stavrakaki

Dr. Maddie Humphrey

Dr. Sandra Laborda Anadon

Dr. Jess Buttress

Dr. James Grimshaw

Dr. Kenneth Holst Seistrup

Dr. Declan Gray

Masters students:

Christopher Martin

Alisa Mondry (Erasmus student)

Zi Qi Ng

Chris Duringer

Yong Jie Chen

Jessica Clark

Ethan Drury

Katie Pearson

Lauren Elliott

Natalie Vardy

James Donahue

Jan Derk te Winkel (Erasmus student)

Stijn Peeters (Erasmus student)

Tim Knetsch (Erasmus student)

Undergraduate students:

Joey Chong

John Nguyen

Ralph Ticman

Edmond Kelly

Jake Smith

Neha Ramchandani Ramchandani

Luc Eppie

Sameer Patil

Garoufallia Stavridou

Talia Peters

Nifemi Opasanya

Nadhir Bhunnoo

Saleena Limbu

Zunera Baig

Alex-Rose Pogmore

James Donahue

Bethany Coley

Undergraduate Teaching

• Teaching in BSc module BGM2061 (Protein Trafficking and Biological Membranes)
• Supervision of undergraduate research projects

 Postgraduate Teaching

• Teaching in MRes module MMB8016 (Molecular Microbiology)
• Supervision of Masters and PhD research projects

• Articles

  • Buttress JA, Schäfer A-B, Koh A, Wheatley J, Mickiewicz K, Wenzel M, Strahl H. . Nature Communications 2025, 16, 10320.
  • Dakes Stavrakakis M, Humphrey M, van Rij T, Harwood CR, Strahl H. . bioRxiv 2025. Submitted.
  • Bohorquez LC, Strahl H, Marenduzzo D, Thiele MJ, Bürmann F, Hamoen LW. . eLife 2025, RP101520.
  • Middlemiss S, Blandenet H, Roberts DM, McMahon A, Grimshaw J, Edwards JM, Sun Z, Whitley KD, Blu T, Strahl H, Holden S. . Nature Communications 2024, (15), 5411.
  • Gray DA, Wang B, Sidarta M, Cornejo FA, Wijnheijmer J, Rani E, Gamba P, Turgay K, Wenzel M, Strahl H, Hamoen LW. . Nature Communications 2024, 15, 6877.
  • Mets T, Kurata T, Ernits K, Johansson MJO, Craig SZ, Evora GM, Buttress JA, Odai R, Coppieters't Wallant K, Nakamoto JA, Shyrokova L, Egorov AA, Doering CR, Brodiazhenko T, Laub MT, Tenson T, Strahl H, Martens C, Harms A, Garcia-Pino A, Atkinson GC, Hauryliuk V. . Cell Host and Microbe 2024, 32(7), 1059-1073.e8.
  • Bonini D, Duggan S, Alnahari A, Brignoli T, Strahl H, Massey RC. . mBio 2024, 15(8), e01512-24.
  • Ernits,K,Saha,CK,Brodiazhenko,T,Chouhan,B,Shenoy,A,Buttress,JA,Duque-Pedraza,JJ,Bojar,V,Nakamoto,JA,Kurata,T,Egorov,AA,Shyrokova,L,Johansson,MJO,Mets,T,Rustamova,A, Dzigurski,J,Tenson,T,Garcia-Pino,A,Strahl,H,Elofsson,A,Hauryliuk,V,Atkinson,GC. . PNAS 2023, 120(33), 2305393120.
  • Macdonald E, Wright R, Connolly JPR, Strahl H, Brockhurst M, van Houte S, Blower TR, Palmer T, Mariano G. . PLoS Genetics 2023, 19(6), e1010784.
  • Koh A, Strahl H, Murray H. . Microbiology 2022, 168(10), 001259.
  • Gohrbandt M, Lipski A, Grimshaw JW, Buttress JA, Baig Z, Herkenhoff B, Walter S, Kurre R, Deckers-Hebestreit G, Strahl H. . EMBO Journal 2022, 41, e109800.
  • Malanovic N, Buttress JA, Vejzovic D, Ön A, Piller P, Kolb D, Lohner K, Strahl H. . Applied and Environmental Microbiology 2022, 88(10), e00180-22.
  • Kurata T, Saha CK, Buttress JA, Mets T, Brodiazhenko T, Turnbull KJ, Awoyomi OF, Alves Oliveira SR, Jimmy S, Ernits K, Delannoy M, Persson K, Tenson T, Strahl H, Hauryliuk V, Atkinson GC. . Proceedings of the National Academy of Sciences 2022, 119(6), e2102212119.
  • Buttress JA, Halte M, te Winkel JD, Erhardt M, Popp PF, Strahl H. . Microbiology 2022, 168(9), 001227.
  • Popp PF, Benjdia A, Strahl H, Berteau O, Mascher T. . Frontiers in Microbiology 2020, 11, 151.
  • Ndeh D, Baslé A, Strahl H, Yates EA, McClurgg UL, Henrissat B, Terrapon N, Cartmell A. . Nature Communications 2020, 11, 646.
  • Jimmy S, Saha CK, Kurata T, Stavropoulos C, Alves Oliveira SR, Koh A, Cepauskas A, Takada H, Rejman D, Tenson T, Strahl H, Garcia-Pino A, Hauryliuk V, Atkinson GC. . Proceedings of the National Academy of Sciences of the United States of America 2020, 117(19), 10500-10510.
  • Ulhuq FR, Gomes MC, Duggan G, Guo M, Mendonca C, Buchanan G, Chalmers JD, Cao Z, Kneuper H, Murdoch S, Thomson S, Strahl H, Trost M, Mostowy S, Palmer T. . Proceedings of the National Academy of Sciences of the United States of America 2020, 117(34), 20836-20847.
  • Gray D, Dugar G, Gamba P, Strahl H, Jonker MJ, Hamoen LW. . Nature Communications 2019, 10, 890.
  • Murina V, Kasari M, Takada H, Hinnu M, Saha CK, Grimshaw JW, Seki T, Reith M, Putrins M, Tenson T, Strahl H, Hauryliuk V, Atkinson GC. . Journal of Molecular Biology 2019, 431(18), 3568-3590.
  • Mariano G, Trunk K, Williams D, Monlezun L, Strahl H, Pitt S, Coulthurst S. . Nature Communications 2019, 10, 5484.
  • Trunk K, Peltier J, Liu Y-C, Dill BD, Walker L, Gow NAR, Stark MJR, Quinn J, Strahl H, Trost M, Coulthurst SJ. . Nature Microbiology 2018, 3, 920-931.
  • Pogmore AR, Seistrup KH, Strahl H. . Microbiology 2018, 164, 475-482.
  • Floros VI, Pyle A, Dietmann S, Wei W, Tang WWC, Irie N, Payne B, Capalbo A, Noli L, Coxhead J, Hudson G, Crosier M, Strahl H, Khalaf Y, Saitou M, Ilic D, Surani MA, Chinnery PF. . Nature Cell Biology 2018, 20, 144-151.
  • Kepplinger B, Morton S, Seistrup K, Marrs E, Hopkins A, Perry J, Strahl H, Hall M, Errington J, Allenby N. . ACS Chemical Biology 2018, 13(1), 207-214.
  • Saaki TNV, Strahl H, Hamoen LW. . Journal of Bacteriology 2018, 200(9), e00658-17.
  • Wenzel M, Vischer NOE, Strahl H, Hamoen LW. . Bio-protocol 2018, 8(20), e3063.
  • Sim M, Koirala S, Picton D, Strahl H, Hoskissin PA, Rao CV, Gillespie CS, Aldridge PD. . Scientific Reports 2017, 7, 41189.
  • Scheinpflug K, Wenzel M, Krylova O, Bandow JE, Dathe M, Strahl H. . Scientific Reports 2017, 7, 44332.
  • Müller A, Wenzel M, Strahl H, Grein F, Saaki TNV, Kohl B, Siersma T, Bandow JE, Sahl H-G, Schneider T, Hamoen LW. . Proceedings of the National Academy of Sciences of the United States of America 2016, 113(45), E7077-E7086.
  • te Winkel JD, Gray DA, Seistrup KH, Hamoen LW, Strahl H. . Frontiers in Cell and Developmental Biology 2016, (4), 29.
  • Strahl H, Ronneau S, SolanaGonzález B, Klutsch D, Schaffner-Barbero C, Hamoen LW. . Nature Communications 2015, 6, 8728.
  • Strahl H, Turlan C, Khalid S, Bond PJ, Kebalo J-M, Peyron P, Poljak L, Bouvier M, Hamoen L, Luisi BF, Carpousis AJ. . Plos Genetics 2015, 11(2), e1004961.
  • Jahn N, Brantl S, Strahl H. . Molecular Microbiology 2015, 98(4), 651-666.
  • Strahl H, Bürmann F, Hamoen LW. . Nature Communications 2014, 5, 3442.
  • Brockmann B, Koop KD, Strahl H, Deckers-Hebestreit G. . Journal of Bacteriology 2013, 195(18), 4074-4084.
  • Duman R, Ishikawa S, Celik I, Strahl H, Ogasawara N, Troc P, Löwe J, Hamoen LW. . Proceedings of the National Academy of Sciences of the USA 2013, 110(48), E4601–E4610.
  • Kixmüller D, Strahl H, Wende A, Greie JC. . Extremophiles 2011, 15(6), 643-652.
  • Strahl H, Hamoen LW. . Proceedings of the National Academy of Sciences 2010, 107(27), 12281-12286.
  • Strahl H, Greie J-C. . Extremophiles 2008, 12(6), 741-752.
  • Kirstein J, Strahl H, Moliere N, Hamoen LW, Turgay K. . Molecular Microbiology 2008, 70(3), 682-694.

• Book Chapters

  • Humphrey M, Abdelmesseh Nekhala I, Scheinpflug K, Krylova O, Schäfer A-B, Buttress JA, Wenzel M, Strahl H. . In: Peter Sass, ed. Antibiotics. New York: Humana, New York, NY, 2022, pp.203-229.
  • Scheinpflug K, Krylova O, Strahl H. . In: Sass P, ed. Antibiotics: Methods and Protocols. Springer New York, 2017, pp.159-174.

• Reviews

  • Harrison MA, Strahl H, Dawson LF. . Current Opinion in Microbiology 2022, 65, 131-137.
  • Strahl H, Errington J. . Annual Review of Microbiology 2017, 71, 519-538.
  • Strahl H, Hamoen LW. . Current Opinion in Microbiology 2012, 15(6), 731-736.