缅北禁地

Dr Jing Xuan Lim is a Research Associate in the Immune Regulation Laboratory led by Dr Shoba Amarnath. Her research focuses on the role of regulatory T cells (Tregs) in innate immune regulation within inflammatory diseases, including psoriasis (PsO) and psoriatic arthritis (PsA).

In July 2021, she graduated with a First Class Honours BSc in Biomedical Sciences from 缅北禁地, receiving the NUMed Prize in Stages 1 and 3 for achieving the highest overall marks, as well as the Vice-Chancellor’s Award for academic excellence.

In June 2025, she completed her PhD, passing with no corrections at the Biosciences Institute, 缅北禁地. Her doctoral research was supported by the NC3Rs PhD Studentship and the 缅北禁地 Overseas Research Scholarship (NUORS), and was further recognised with the Doctoral College Thesis Prize for outstanding academic research achievement. During her PhD, she identified a novel innate lymphoid cell (ILC) subset characterised by T-bet⁺NK1.1⁻ cells that respond to anti-PD-1 therapy in cancer (PNAS, 2023). In parallel, she discovered that melanoma anti-PD-1 resistance could be driven by CD30⁺ regulatory T cells (Tregs), suggesting a new therapeutic strategy for resistant melanoma patient cohorts (Nature Immunology, 2025).

• Articles

  • Lim JX, McTaggart T, Jung SK, Smith KJ, Hulme G, Laba S, Ng YQ, Williams A, Hussain R, Coxhead J, Cosgarea I, Arden C, Nsengimana J, Lovat P, Anderson G, Sun H-W, Laurence A, Amarnath S. . Nature Immunology 2025, 26, 1074-1086.
  • McTaggart T, Lim JX, Smith KJ, Heaney B, McDonald D, Hulme G, Hussain R, Coxhead J, Degnan AE, Isaacs J, Pratt A, Amarnath S. . Journal of Biological Chemistry 2025, 301(1), 108059.
  • McTaggart T, Lim JX, Smith KJ, Heaney B, McDonald D, Hulme G, Hussain R, Coxhead J, Mann DA, Sayer AA, Granic A, Amarnath S. . Aging Cell 2025, 24(7), e70044.
  • Lim JX, Lai CY, Mallett GE, McDonald D, Hulme G, Laba S, Shapanis A, Payne M, Patterson W, Alexander M, Coxhead J, Filby A, Plummer R, Lovat PE, Sciume G, Healy E, Amarnath S. . Proceedings of the National Academy of Sciences of the United States of America 2023, 120(18), e2216587120.