缅北禁地

Previously Consultant Cardiothoracic Surgeon, Edinburgh 1986-87, Freeman Hospital 1987-2017

National Clinical Lead for Governance, Organ Donation and Transplantation, NHSBT  2012-2018

Clinical Profile

I headed the cardiac and pulmonary transplant programme at the Freeman hospital for over 20 years, building it into the most active in the UK, and resumed a lead role in the transplant programme in March 2016.

 Clinical interests were in adult heart and lung transplantation, complex aortic surgery, and mitral and aortic valve repair, but I performed the full range of procedures within adult cardiac surgery. I was a consultant cardiothoracic surgeon for over 30 years and previously maintained a very busy and varied clinical workload. I retired from clinical practice at the end of August 2017, but as a result of ongoing research programmes, maintain a close contact with the clinical service in 缅北禁地.

Current Roles and Responsibilities

Professor of Cardiothoracic Surgery, NUTCRI

CI, SIGNET Trial

Qualifications MB.BS 1976 FRCS, Edinburgh, London, 1980 FRCP Edinburgh 1992, London 2002, FETCS 1996

Memberships

Honours and Awards

Past-President of both the European Society for Organ Transplantation (ESOT) and the International Society for Heart and Lung Transplantation (ISHLT).

Awarded Honorary FRCP Edinburgh 1995, London 2002

Honeyman Gillespie Lecture; Edinburgh, 1988, Sydney Watson Smith Lecture; RCP Edinburgh, 1994, Clement Price-Thomas Award RCS England 1995,Tudor Edwards Lecturer RCS England 1999, Hilary Festenstein Lecturer, BSHI 2014

James lV Professor RCS Edinburgh in 2003, 

Mortimer J Buckley Visiting Professor at the Massachusetts General Hospital in 2017 and Visiting Professor, Centre Hospitalier de Universitaire Montreal (CHUM) October 2018

Extensive experience in clinical and laboratory research, going back over 30 years. Supervision of a number of Mres projects, MD’s and three recent PhD’s, all completed. Recognised as a PI within the Translational and Clinical Research Institute , 缅北禁地

Research interests centred around clinical heart and lung transplantation, reperfusion injury in the lung and then pathophysiology of brain stem death. We had an active interest in clinical EVLP and I was a PI for the 缅北禁地-based DEVELOP-UK Trial. Current research is focussed on donor pathophysiology, therapeutic donor interventions and ex-vivo organ perfusion.

One PhD Fellow, supported by MRC Clinical Training Research Fellowship, carrying out work with a novel ex-vivo hypothermic Oxygenated Perfusion (HOP) system

One PhD Fellow, supported by NHSBT (CTAG Audit Fellow) working on a lung donor score and improved organ utilisation

I co-chair Theme 1 of the Cambridge/缅北禁地 NIHR funded Blood and Transplant Research Unit (BTRU)

CI, SIGNET 2020-2025

Local PI ART, 2008-10, QUOD, 2012 to present, QUOD/MRC Expansion 2017 to present.

Chair of DMP for PITHIA 2017 to present, member of DMP for ARISE 2014-9

National teaching to SCTS Research programme, National Student Surgical Society

Regional teaching on FRCS Cardiothoracic Course

Local Involvement in NESTAC

Teaching on Mres Transplantation module

• Fisher AJ, Dark JH. . Nature Medicine 2020, 26, 1015-1016.
• Manara A, Shemie SD, Large S, Healey A, Baker A, Badiwala M, Berman M, Butler AJ, Chaudhury P, Dark J, Forsythe J, Freed DH, Gardiner D, Harvey D, Hornby L, MacLean J, Messer S, Oniscu GC, Simpson C, Teitelbaum J, Torrance S, Wilson LC, Watson CJE. . American Journal of Transplantation 2020, 20(8), 2017-2025.
• Wang L, Wang T, Rushton SN, Parry G, Dark JH, Sheerin NS. . Transplant International 2020, 33(12), 1650-1666.
• MacGowan GA, Dark JH, Corris PA, Nair AR. . Transplant International 2019, 32(10), 1019-1027.
• Khushnood A, Butt TA, Jungschleger J, Henderson P, Smith JH, De Rita F, Nassar M, Page A, Messer S, Large S, Dark JH, Parry G, Reinhardt Z, Hasan A. . Pediatric Transplantation 2019, 23(6), e13536.
• Dark JH. . Journal of Thoracic and Cardiovascular Surgery 2018, 155(1), 438-439.
• Dark JH. . Journal of Thoracic and Cardiovascular Surgery 2018, 156(3), 1303-1304.
• Bayliss CD, Booth KL, Williams R, Dark JH, Gould KF. . Annals of Thoracic Surgery 2017, 104(5), e379-e381.
• Andreasson ASI, Karamanou DM, Gillespie CS, Özalp F, Butt T, Hill P, Jiwa K, RWalden H, Green NJ, Borthwick LA, Clark SC, Pauli H, Gould KF, Corris PA, Ali S, Dark JH, Fisher AJ. . European Journal of Cardio-thoracic Surgery 2017, 51(3), 577-586.
• Diamond JM, Arcasoy S, Kennedy CC, Eberlein M, Singer JP, Patterson GM, Edelman JD, Dhillon G, Pena T, Kawut SM, Lee JC, Girgis R, Dark J, Thabut G. . Journal of Heart and Lung Transplantation 2017, 36(10), 1104-1113.
• Urban M, Booth K, O'Sullivan J, Dark J. . Annals of Thoracic Surgery 2018, 106(1), e1-e2.
• Birch J, Sunny SS, Hester KLM, Parry G, Kate Gould F, Dark JH, Clark SC, Meachery G, Lordan J, Fisher AJ, Corris PA, De Soyza A. . BMC Pulmonary Medicine 2018, 18, 82.
• Dark JH. . Thoracic Surgery Clinics 2018, 28(3), 357-363.
• Dark JH, Hasan A. . Annals of Cardiothoracic Surgery 2018, 7(1), 2-2.
• Jungschleger JGM, Boldyrev SY, Kaleda VI, Dark JH. . Annals of Cardiothoracic Surgery 2018, 7(1), 169-171.
• Dimarakis I, Banner NR, Rushton S, Wong HSE, Berman M, Howell N, Payne J, Dark J, Mehew J, Venkateswaran R. . European Journal of Cardio-thoracic Surgery 2018, 53(6), 1135-1143.
• Kenny LA, DeRita F, Nassar M, Dark J, Coats L, Hasan A. . Annals of Cardiothoracic Surgery 2018, 7(1), 152-159.
• Wood G, Booth K, Khan Z, Biss T, Roysam C, Dark J. . Asian Cardiovascular and Thoracic Annals 2017, 25(9), 635-637.
• Hardman G, Dark JH. . Journal of Thoracic and Cardiovascular Surgery 2021, 162(5), 1489-1490.
• Wang L, Dark JH. . Surgery 2020, 38(7), 375-381.
• Hardman G, Hogg R, Rushton S, Booth K, Fisher AJ, Dark JH. . The Journal of Heart and Lung Transplantation 2020, 39(4), S139-S139.
• Booth K, Dark JH. . Journal of Thoracic and Cardiovascular Surgery 2019, 158(6), E187-E188.
• Kanagasundaram NS, Baudouin SV, Rowling S, Prabhu M, Dark JH, Goodship THJ, Chinnery PF, Hudson G. . Scientific Reports 2019, 9, 2279.
• Fisher A, Andreasson A, Chrysos A, Lally J, Mamasoula C, Exley C, Wilkinson J, Qian J, Watson G, Lewington O, Chadwick T, McColl E, Pearce M, Mann K, McMeekin N, Vale L, Tsui S, Yonan N, Simon A, Marczin N, Mascaro J, Dark J. . Health Technology Assessment 2016, 20(85).
• Hardman G, Sutcliffe R, Hogg R, Mumford L, Grocott L, Jerrett L, Mead-Regan S-J, Nuttall J, Dunn S, Seeley P, Quigley R, Dalzell JR, Al-Attar N, Parameshwar J, Fisher AJ, Booth K, Dark JH. . Clinical Transplantation 2021, 35(5), e14261.
• Hardman G, Sutcliffe R, Hogg R, Mumford L, Grocott L, Mead-Regan S-J, Nuttall J, Dunn S, Seeley P, Clark S, Quigley R, Al-Attar N, Booth K, Dark JH, Fisher AJ. . Clinical Transplantation 2021, 35(3), e14210.
• Wang L, MacGowan GA, Ali S, Dark JH. . Journal of Heart and Lung Transplantation 2020, 40(1), 69-86.
• Wang L, Andreasson A, Straughan C, Sims AJ, Brennan KJ, Fisher AJ, Clark SC, Parry G, Booth KL, Dark JH. . In: 39th International Society for Heart and Lung Transplantation Annual Meeting and Scientific Sessions. 2019, Orlando, Florida USA: Elsevier.