缅北禁地

Current Position

Manager - Genomics Core Facility 

Background

I have been using genomic technologies in both research and commercial settings for over fifteen years and have extensive experience in the application of next-generation sequencing (NGS); working with clients in diagnostic, academic, government, and commercial sectors. I established (2016) and currently manage the Faculty of Medical Sciences 'Genomics Core Facility'; a NGS lab that specialises in single-cell and spatial transcriptomic applications. I have a research background in both cancer biology and mitochondrial genetics.

Qualifications

PhD, Cancer biology / nutrigenomics, 缅北禁地, 2003.

BSc (Hons), Physiology, University of Sunderland, 1997 (Four-year sandwich degree including one-year industrial placement at the Jack Birch Unit for Molecular Carcinogenesis, University of York 1995-1996).

Previous Positions

Research Associate, 缅北禁地, NIHR / BRC, 2012-2016

Senior Scientist, NewGene Limited, 2007-2012.

Research Associate, 缅北禁地, Human Nutrition, 2002-2007.

Research Technician, University of York, Jack Birch Unit for Molecular Carcinogenesis, 1997-1999.

Esteem Indicators

Member of UK NEQAS Special Advisory Group for Next Generation Sequencing Quality Assessment 

Key Words

Genomics / Next-Generation sequencing / Single-cell / Transcriptomics / Spatial Gene Expression / DNA / RNA / ddPCR

• Payne BAI, Wilson IJ, Yu-Wai-Man P, Coxhead J, Deehan D, Horvath R, Taylor RW, Samuels DC, Santibanez-Koref M, Chinnery PF. . Human Molecular Genetics 2012, 22(2), 384-390.
• Borras S, Bromley D, Scully P, Coxhead JM, Spiden S, Short J, Robinson J, Huntley D, Curtis A, Taylor R. . In: European Human Genetics Conference 2012. 2012, Nürnberg, Germany: Nature Publishing Group.
• Al-Balool HH, Weber D, Liu Y, Wade M, Guleria K, Nam PL, Clayton J, Rowe W, Coxhead J, Irving J, Elliott DJ, Hall AG, Santibanez-Koref M, Jackson MS. . Genome Research 2011, 21(11), 1788-1799.
• Frey A, Coxhead J, Curtis A. Solid Phase Sequence Capture vs PCR Targeted Enrichment of Muscular Dystrophy genes for Next Generation Sequencing. In: British Human Genetics Conference 2010. 2010, Warwick, RI: BMJ Publishing Group.
• Leaver M, Dominguez-Cuevas P, Coxhead JM, Daniel RA, Errington J. . Nature 2009, 457(7231), 849-853.
• Stanley L, Coxhead J, Burn J, Curtis A. . In: British Human Genetics Conference 2008. 2008, University of York, UK: Journal of Medical Genetics: BMJ Group.
• Tzoulis C, Tran GT, Coxhead J, Bertelsen B, Lilleng PK, Balafkan N, Payne B, Miletic H, Chinnery PF, Bindoff LA. . Annals of Neurology 2014, 76(1), 66-81.
• Pfeffer G, Gorman GS, Griffin H, Kurzawa-Akanbi M, Blakely EL, Wilson I, Sitarz K, Moore D, Murphy JL, Alston CL, Pyle A, Coxhead J, Payne B, Gorrie GH, Longman C, Hadjivassiliou M, McConville J, Dick D, Imam I, Hilton D, Norwood F, Baker MR, Jaiser SR, Yu-Wai-Man P, Farrell M, McCarthy A, Lynch T, McFarland R, Schaefer AM, Turnbull DM, Horvath R, Taylor RW, Chinnery PF. . Brain 2014, 137(5), 1323-1336.
• Łastowska M, Al-Afghani H, Al-Balool HH, Sheth H, Mercer E, Coxhead JM, Redfern CPF, Peters H, Burt AD, Santibanez-Koref M, Bacon CM, Chesler L, Rust AG, Adams DJ, Williamson D, Clifford SC, Jackson MS. . Acta Neuropathologica Communications 2013, 1, 35.
• Pyle A, Hudson G, Wilson IJ, Coxhead J, Smertenko T, Herbert M, Santibanez-Koref M, Chinnery PF. . PLoS Genetics 2015, 11(5), e1005040.
• Collin J, Zerti D, Queen R, SantoFerreira T, Bauer R, Coxhead J, Hussain R, Steel D, Mellough C, Ader M, Sernagor E, Armstrong L, Lako M. . Stem Cells (Durham) 2019, 37(5), 609-622.
• Collin J, Queen R, Zerti D, Dorgau B, Hussain R, Coxhead J, Cockell S, Lako M. . Stem Cells (Durham) 2019, 37(5), 593-598.
• Duncan CJA, Dinnigan E, Theobald R, Grainger A, Skelton AJ, Hussain R, Willet JDP, Swan DJ, Coxhead J, Thomas MF, Thomas J, Zamvar V, Slatter MA, Cant AJ, Engelhardt KR, Hambleton S. . Annals of the Rheumatic Diseases 2018, 77(5), 783-786.
• Keogh MJ, Wei W, Aryaman J, Walker L, van den Ameele J, Coxhead J, Wilson I, Bashton M, Beck J, West J, Chen R, Haudenschild C, Bartha G, Luo S, Morris CM, Jones NS, Attems J, Chinnery PF. . Nature Communications 2018, 9(1), 4257.
• Floros VI, Pyle A, Dietmann S, Wei W, Tang WWC, Irie N, Payne B, Capalbo A, Noli L, Coxhead J, Hudson G, Crosier M, Strahl H, Khalaf Y, Saitou M, Ilic D, Surani MA, Chinnery PF. . Nature Cell Biology 2018, 20, 144-151.
• Keogh MJ, Wei W, Wilson I, Coxhead J, Ryan S, Rollinson S, Griffin H, Kurzawa-Akanbi M, Santibariez-Koref M, Talbot K, Turner MR, McKenzie CA, Troakes C, Attems J, Smith C, Al Sarraj S, Morris CM, Ansorge O, Pickering-Brown S, Ironside JW, Chinnery PF. . Genome Reseach 2017, 27(1), 165-173.
• Wei W, Keogh MJ, Wilson I, Coxhead J, Ryan S, Rollinson S, Griffin H, Kurzawa-Akanbi M, Santibanez-Koref M, Talbot K, Turner MR, McKenzie CA, Troakes C, Attems J, Smith C, Al Sarraj S, Morris CM, Ansorge O, Pickering-Brown S, Ironside JW, Chinnery PF. . Acta Neuropathologica Communications 2017, 5, 17.
• Lindsay SJ, Xu YB, Lisgo SN, Harkin LF, Copp AJ, Gerrelli D, Clowry GJ, Talbot A, Keogh MJ, Coxhead J, Santibanez-Koref M, Chinnery PF. . Frontiers in Neuroanatomy 2016, 10, 86.
• Coxhead J, Kurzawa-Akanbi M, Hussain R, Pyle A, Chinnery P, Hudson G. . Neurobiology of Aging 2016, 38, 217.e1-217.e6.
• Payne BAI, Gardner K, Coxhead J, Chinnery PF. . In: Mitochondrial Medicine. Springer New York, 2015, pp.59-66.
• Collin J, Queen R, Zerti D, Dorgau B, Georgiou M, Djidrovski I, Hussain R, Coxhead JM, Joseph A, Rooney P, Lisgo S, Figueiredo FC, Armstrong L, Lako M. . The Ocular Surface 2020, 19, 190-200.
• Davies HR, Hodgson K, Schwalbe E, Coxhead J, Sinclair N, Zou X, Cockell S, Husain A, Nik-Zainal S, Rajan N. . Nature Communications 2019, 10, 4717.
• Lowes H, Robertson F, Pyle A, Hussain R, Coxhead J, Yarnall AJ, Burn D, Payne BAI, Santibanez-Koref M, Hudson G. . Movement Disorders 2020, 35(12), 2134-2136.