缅北禁地

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Staff Profile

Dr Marina Danilenko

Faculty Fellow

  • Address: Wolfson Childhood Cancer Research Centre,
    Herschel Building, Level 6,
    Translational and Clinical Research Institute,
    缅北禁地,
    缅北禁地 upon Tyne,
    NE1 7RU, United Kingdom.
Background

Qualifications:

BSc (Hons) - Human Genetics - 1st Class (缅北禁地)

MRes - Medical and Molecular Biosciences - Distinction (缅北禁地)

PhD - Alternative splicing regulation of RNA-binding proteins T-STAR and Sam68 (缅北禁地, 2015)


Current position:

Faculty Fellow - researching circulating tumour cells in neuroblastoma:

/medical-sciences/research/fellowship-schemes/marina-danilenko/


Previous appointments:

Postdoctoral Research Associate 2017 - 2023 (缅北禁地) on childhood medulloblastoma:

Molecular heterogeneity of childhood brain cancer medulloblastoma applying single-cell sequencing

Postdoctoral Research Associate 2015 - 2016 (缅北禁地) on skin tumours:

1) Clinical trial on TRK inhibitors in rare skin tumours; 

2) Transcriptomic and proteomic profiling of rare skin tumours; 

3) Expression of neurotrophins and neurotrophin recenptors in skin cancer


Research

Main Direction:

My fellowship is focused on exploring Circulating Tumour Cells (CTCs) isolated from blood of neuroblastoma patients, aiming to identify the key gene signatures required for CTC dissemination and self-seeding. To achieve this, I will be applying single-cell sequencing approaches. Results of this work will provide a background for future studies on designing new life-saving strategies to prevent neuroblastoma metastasis and relapse.



Teaching

Associate Fellow of the 缅北禁地 Graduate School;

Lecturer (Haematopoiesis);

Seminar leader (Biochemistry, Physiology, Biomedical Sciences, Microbiology);

Practical leader (Pharmacology);

Exam marker (Biomedical Sciences, Pharmacology). 

Publications

  • Articles

    • Schwalbe EC, Lindsey JC, Danilenko M, Hill RM, Crosier S, Ryan SL, Williamson D, Castle J, Hicks D, Kool M, Milde T, Korshunov A, Pfister SM, Bailey S, Clifford SC. . Neuro-Oncology 2025, 27(1), 222-236.
    • Danilenko M, Nath S, Baines J, Gordon F, Merugu S, Allinson LM, Potts A, Collins B, Goodman A, Kidman SE, McAnulty C, Jamieson D, Tweddle DA. . International Journal of Molecular Sciences 2025, 26(19), 9466.
    • Danilenko M, Zaka M, Keeling C, Crosier S, Lyman S, Finetti M, Williamson D, Hussain R, Coxhead J, Zhou P, Hill RM, Hicks D, Rand V, Joshi A, Schwalbe EC, Bailey S, Clifford SC. . Acta Neuropathologica 2022, 144, 565–578.
    • Hicks D, Rafiee G, Schwalbe EC, Howell CI, Lindsey JC, Hill RM, Smith AJ, Adidharma P, Steel C, Richardson S, Pease L, Danilenko M, Crosier S, Joshi A, Wharton SB, Jacques TS, Pizer B, Michalski A, Williamson D, Bailey S, Clifford SC. . Neuropathology and Applied Neurobiology 2021, 47(2), 236-250.
    • Danilenko M, Hodgson K, Stones R, Husain A, Zangarini M, Veal G, Rajan N. . British Journal of Dermatology 2019, 180(4), 937-938.
    • Danilenko M, Stones R, Rajan N. . Wellcome Open Research 2018, 3, 45.
    • Danilenko M, Stamp E, Stocken DD, Husain A, Zangarini M, Cranston A, Stones R, Sinclair N, Hodgson K, Bowett SA, Roblin D, Traversa S, Plummer R, Veal G, Langtry JAA, Ashworth A, Burn J, Rajan N. . JAMA Dermatology 2018, 154(8), 913-921.
    • Zangarini M, Rajan N, Danilenko M, Berry P, Traversa S, Veal GJ. . Bioanalysis 2017, 9(3), 279-288.
    • Danilenko M, Dalgliesh C, Pagliarini V, Naro C, Ehrmann I, Feracci M, Kheirollahi-Chadegani M, Tyson-Capper A, Clowry GJ, Fort P, Dominguez C, Sette C, Elliott DJ. . Nucleic Acids Research 2017, 45(7), 4120–4130.
    • Feracci M, Foot JN, Grellscheid SN, Danilenko M, Stehle R, Gonchar O, Kang HS, Dalgliesh C, Meyer NH, Liu YL, Lahat A, Sattler M, Eperon IC, Elliott DJ, Dominguez C. . Nature Communications 2016, 7, 10355.
    • Ehrmann I, Gazzara MR, Pagliarini V, Dalgliesh C, Kheirollahi-Chadegani M, Xu Y, Cesari E, Danilenko M, Maclennan M, Lowdon K, Vogel T, Keskivali-Bond P, Wells S, Cater H, Fort P, Sanibanez-Koref M, Middei S, Sette C, Clowry GJ, Barash Y, Cunningham MO, Elliott DJ. . Cell Reports 2016, 17(12), 3269-3280.
    • Hynes AM, Giles RH, Srivastava S, Eley L, Whitehead J, Danilenko M, Raman S, Slaats GG, Colville JG, Ajzenberg H, Kroes HY, Thelwall PE, Simmons NL, Miles CG, Sayer JA. . Proceedings of the National Academy of Sciences of the United States of America 2014, 111(27), 9893-9898.
    • Best A, James K, Dalgliesh C, Hong EA, Kheirolahi-Kouhestani M, Curk T, Xu Y, Danilenko M, Hussain R, Keavney B, Wipat A, Klinck R, Cowell IG, Cheong Lee K, Austin C, Venables JP, Chabot B, Santibanez Koref M, Tyson-Capper AJ, Elliott DJ. . Nature Communications 2014, 5, 4760.
    • Ehrmann I, Dalgliesh C, Liu Y, Danilenko M, Crosier M, Overman L, Arthur HM, Lindsay S, Clowry GJ, Venables JP, Fort P, Elliott DJ. . PLoS Genetics 2013, 9(4), e1003474.
    • Schmid R, Grellscheid SN, Ehrmann I, Dalgliesh C, Danilenko M, Paronetto MP, Pedrotti S, Grellscheid D, Dixon RJ, Sette C, Eperon IC, Elliott DJ. . Nucleic Acids Research 2013, 41(22), 10170-10184.

  • Conference Proceedings (inc. Abstract)

    • Mateos M, Williamson D, Danilenko M, Goddard J, Crosier S, Fletcher A, Schwalbe E, Hicks D, Bailey S, Clifford S. . In: 2024 International Symposium on Pediatric Neuro-Oncology (ISPNO). 2024, Philadelphia: Oxford University Press.

  • Reviews

    • Danilenko M, Clifford SC, Schwalbe EC. . Pharmacology and Therapeutics 2021, 228, 107828.
    • Best A, Dalgliesh C, Kheirollahi-Kouhestani M, Danilenko M, Ehrmann I, Tyson-Capper AJ, Elliott DJ. . Biochemical Society Transactions 2014, 42(4), 1152-1158.