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Staff Profile

Nicole O'Connor

Research Assistant (Evidence Synthesis and Horizon Scanning)

  • Email: nicole.oconnor@ncl.ac.uk
  • Personal Website:
  • Address:
    NIHR Innovation Observatory and Evidence Synthesis Group
    The Catalyst
    Room 3.12
    3 Science Square
    缅北禁地 Helix
    缅北禁地 upon Tyne
    United Kingdom
    NE4 5TG
Background

About me

After completing a training fellowship in evidence synthesis with Cochrane, I am now a healthcare researcher in evidence synthesis at the . My work centres around the correct application and development of secondary research methods and health technology assessment (HTA) processes across many healthcare topics. Earlier academic experience includes working with the rare neuromuscular disease community, clinical academics, and industry to support the delivery of a clinical trial and natural history studies and then latterly leading the co-creation of a two-year programme to disseminate standards of care internationally.


About the NIHR Innovation Observatory

The NIHR Innovation Observatory is a world leading health and care innovation scanning centre providing data-driven insights to foster innovation and equitable access to high quality care. We aim to transform health systems and improve population health by providing advanced data-driven insights that foster innovation and equitable access to high quality care. At the core of our work is the development of data-driven methods to identify, capture and synthesise intelligence on new health innovations. We develop and share cutting edge methods in horizon scanning, building capacity in the systems across the public, voluntary and industry sectors.

We deliver essential intelligence and insights about medicines and MedTech innovation to the National Institute of Health and Care Excellence (NICE), NHS England, the Medicines and Healthcare Products Regulatory Agency (MHRA), the NIHR, the UK Health Security Agency, the Department for Health and Social Care and industry - allowing these organisations to prepare for policies, regulation and frontline delivery for new, emerging and disruptive technologies.



Research

Current core activities

  • Applying evidence synthesis methods to answer priority research questions. I have experience working in multi-disciplinary teams to produce systematic reviews, scoping reviews, evidence gap maps and horizon scanning reports. Other research methods I have experience with include semi-structured interviews and the early stages of a core outcome set development.


  • Working with a team of information specialists and health economists with the . The TAR group independently appraises the clinical and cost-effectiveness of health technologies submitted to NICE for potential use within the NHS. I have experience and an interest in working on appraisals for Highly Specialised Technologies.


  • Writing and reviewing for medicines identified via as relevant to the UK healthcare system. The health technology briefings are an early step in the NICE topic selection process and aim to facilitate timely market access and delivery to patients.


Teaching

I contribute to teaching and marking for the compulsory module, 'Introduction to Systematic Reviewing and Critical Appraisal,' as part of the Public Health and Health Services Research MSc/MPH program.

I have co-supervised undergraduate and postgraduate student dissertations. I would be open to supervising students undertaking systematic, scoping, or rapid reviews.


Publications

  • Articles

    • Johnson EE, Orozco Leal G, Still M, O'Connor N, Jayachandran L, Robinson T, Meader N, Kenny RPW, Wallace SA, Garcia Gonzalez-Moral S, Vale L, Parker R, Rice S, Sagoo GS, Pearson F. . International Journal of Technology Assessment in Health Care 2025, 41(1), e64.
    • Vesentini G, O'Connor N, Le Berre M, Nabhan AF, Wagg A, Wallace SA, Dumoulin C. . Cochrane Database of Systematic Reviews 2025, (11), CD015376.
    • Moradi N, O'Connor N, Thomson KH, Shabaninejad H, Sotire T, Still M, Fernandez-Garcia C, Wallace SA, Williams O, Vale L, Sagoo GS. . PharmacoEconomics 2024, 42, 913-917.
    • Johnson EE, O'Connor N, Hilton P, Pearson F, Goh J, Vale L. . PLOS Global Public Health 2023, 3(1), e0001481.
    • Beyer F, Rice S, Orozco-Leal G, Still M, O'Keefe H, O'Connor N, Stoniute A, Craig D, Pereira S, Carr L, Leeds J. . Health Technology Assessment 2023, 27(7), 1-118.
    • O'Connor N, Thomson KH, Gill S, Jackson S, Wallace SA, Pearson F. . Journal of Clinical Epidemiology 2023, 154, 178-187.
    • Thomson KH, O'Connor N, Dangova KT, Gill S, Jackson S, Bliss DZ, Wallace SA, Pearson F. . BMJ Open Gastroenterology 2022, 9, e000847.
    • Vesentini G, O'Connor N, Elders A, Le Berre M, Nabhan AF, Wagg A, Cacciari L, Dumoulin C. . Cochrane Database of Systematic Reviews 2022, (8), CD015376.
    • Thomson KH, Dangova K, Bliss DZ, Wallace S, O'Connor N, Richter HE, Pearson F. . BMJ Innovations 2022, 8(4), 278-284.

  • Book Chapter

    • O'Connor N, Pearson F, Gill S, Ghasri S, Wallace SA, Thomson KH. . In: Bliss, DZ, ed. Management of Fecal Incontinence for the Advanced Practice Nurse: Under the auspices of the International Continence Society. Cham: Springer, 2025, pp.369-385.

  • Conference Proceedings (inc. Abstracts)

    • O'Connor N, Eastaugh C, Lister J, McDaid C, Hewitt C, Craig D, Norman G. . In: Futures, Foresight & Horizon Scanning Conference 2024. 2025, 缅北禁地 upon Tyne, UK: German Medical Science (GMS) Publishing House.
    • Akinbolade S, Nesworthy J, Fairbairn R, O'Connor N, Hussain A, Harris B, Craig D. . In: HTAi Annual Meeting. 2024, Seville, Spain: Cambridge University Press.
    • Vesentini G, O'Connor N, Le Berre N, Nabhan AF, Wagg A, Wallace S, Dumoulin C. . In: International Continence Society (ICS 2024). 2024, Madrid: Elsevier.
    • O'Connor N. . In: 缅北禁地 Learning and Teaching Conference. 2023, 缅北禁地, UK.
    • Johnson E, O'Connor N, Hilton P, Pearson F, Goh J, Vale L. . In: 27th Cochrane Colloquium. 2023, London: Cochrane.
    • O'Connor N, Johnson EE, Wallace SA, Vale L, Pearson F. . In: Cochrane Colloquium. 2023, London, UK: Cochrane.
    • O'Connor N, Johnson EE, Wallace SA, Vale L, Pearson F. . In: Bladder & Bowel UK National Symposium. 2023, Bolton.
    • O'Connor N, Johnson EE, Wallace SA, Pearson F, Vale L. . In: 7th UK Patient Reported Outcome Measures (PROMs) Research Conference: 'PROMs Across the Lifespan'. 2023, Sheffield, UK: PROMs.
    • Johnson E, O'Connor N, Hilton P, Goh J, Vale L, Pearson F. . In: International Continence Society (ICS 2023). 2023, Toronto: Elsevier BV.
    • O'Connor N, Thomson K, Dangova K, Gill S, Wallace S, Jackson S, Pearson F. . In: Health Technology Assessment international (HTAi) 2022. 2022, Utrecht, the Netherlands: Cambridge University Press.
    • Beyer F, Rice S, Orozco-Leal G, Still M, O'Keefe H, O'Connor N, Stoniute A, Craig D, Pereira S, Carr L, Leeds J. . In: British Society of Gastroenterology (BSG) Annual Meeting. 2021, Online: BMJ Publishing Group.
    • Beyer F, Rice S, Orozco-Leal G, Still M, O'Keefe H, O'Connor N, Stoniute A, Craig D, Pereira S, Carr L, Leeds J. . In: UGI Congress 2021. 2021, Belfast: Oxford University Press.

  • Online Publications

    • O'Connor N, Bushby L, Barnabez J, Wallace S, Garcia-Gonzalez-Moral S, Close H, Pearson F. . 2024. Available at: .
    • Ryburn L, Murphy A, Schroth M, Guyer J, Gonzales JL, Muni-Lofra R, Wittchen A, Ancil B, O'Connor N. . 2018. Available at: .

  • Reports

    • O'Connor N, Wu H, Williams O, Fernandez-Garcia C, Akinbolade S, Ogunyemi A, Gonzalez-Moral SG, Beyer F, Rice S, Meader N. . Manchester: National Institute for Health and Care Excellence, 2025. Highly specialised technologies guidance HST33.
    • O'Connor N, Norman G, Meader N. . 缅北禁地 upon Tyne: Evidence Synthesis Group (ESG), 缅北禁地, 2024.
    • Kenny R, Bhattarai N, O'Connor N, Garcia-Gonzalez S, O'Keefe H, Hosseini-Jebeli S, Meader N, Rice S. . Manchester: National Institute for Health and Care Excellence, 2024. Diagnostics guidance DG61.
    • Thomson K, O'Connor N, Shabaninejad H, Sotire T, Still M, Moradi N, Fernandez-Garcia C, Wallace SA, Williams O, Vale L, Sagoo G. . Manchester: 缅北禁地 Technology Assessment Review (TAR) group, 2023.

  • Review

    • Rice S, Carr K, Sobiesuo P, Shabaninejad H, Orozco-Leal G, Kontogiannis V, Marshall C, Pearson F, Moradi N, O'Connor N, Stoniute A, Richmond C, Craig D, Allegranzi B, Cassini A. . The Lancet Infectious Diseases 2023, 23(7), e228-e239.