缅北禁地

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Staff Profile

Emeritus Professor Oliver James

Emeritus Professor

  • Email: oliver.james@ncl.ac.uk
  • Telephone: +44 (0) 191 208 3868
  • Fax: +44 (0) 191 208 0723
  • Personal Website:
  • Address: Faculty of Medical Sciences
    Medical School
    Framlington Place
    University of 缅北禁地
    缅北禁地 upon Tyne NE2 4HH
    United Kingdom
Background

Roles and Responsibilities

Provost
University:Honorary Degrees Committee
Faculty: Faculty Policy and Resources Committee, Structure Committee
Clinical: Consultant Physician 缅北禁地 upon Tyne Hospitals NHS Trust
Deputy Director Institute for Ageing and Health
Trustee: Help the Aged, Sir James Knott Trust

Qualifications

BA Physiology 1964; MA, BM, BCh 1967;MRCP 1970; FRCP 1981; F.Acad.Med.Sci 1998

Previous Positions

Senior Vice-President Royal College of Physicians 1997-99
Head of Geriatric Medicine, University of 缅北禁地 1985-94

Memberships

British Geriatrics Society
British Society of Gastroenterology
British Association for the Study of the Liver (President 1992-94)
European Association for the Study of the Liver
American Association for the Study of Liver Disease
Internation Association for the Study of the Liver
Association of Physicians
Association of Clinical Professors of Medicine
Academy of Medical Sciences

Research

Research Interests

Primary Biliary Cirrhosis: natural history and epidemiology, risk/pathogenic factors, quality of life
Liver Disease: susceptibility/clinical course of alcoholic and non-alcoholic steatohepatitis, genetics of liver disease

Other Expertise

Stroke, pharmacokinetics in the elderly, digestive disease in the elderly

Future Research

Primary Biliary Cirrhosis: continue geographic and genetic studies, quality of life studies and carry out a "patient centred" control trial of treatment
Study of over 85 year olds in 缅北禁地
Alcohol and the elderly

Funding

Wellcome Trust Training Fellowship £136,920 (with Human Genetics)
MRC Research Career Award £126,000
NHS R&D Research Training Fellowing £83,000 (with Prof C Day)
National Lottery £138,000 (with Prof A Jacoby and Dr D Jones)

Publications
  • Muirhead CR, James OFW, Ducker SJ, McNally RJQ. . Spatial and Spatio-temporal Epidemiology 2015, 14-15, 1-8.
  • McNally RJ, James PW, Ducker S, Norman PD, James OF. . American Journal of Epidemiology 2014, 179(4), 492-498.
  • Martin Ruiz C, Jagger C, Kingston A, Collerton J, Catt M, Davies K, Dunn M, Hilkens C, Keavney B, Pearce S, den Elzen W, Talbot D, Wiley L, Bond J, Mathers J, Eccles M, Robinson L, James O, Kirkwood T, von Zglinicki T. . Mechanisms of Ageing and Development 2011, 132(10), 496-502.
  • Jagger C, Collerton JC, Davies K, Kingston A, Robinson LA, Eccles MP, von Zglinicki T, Martin-Ruiz C, James OFW, Kirkwood TBL, Bond J. . BMC Geriatrics 2011, 11, 21.
  • McNally RJQ, James PW, Ducker S, James OFW. . Hepatology 2011, 54(6), 2099-2103.
  • Watt FE, James OFW, Jones DEJ. . QJM 2004, 97(7), 397-406.
  • Prince MI, Mitchison HC, Ashleigh D, Burke D, Edwards M, Bramble MG, James OFW, Jones DEJ. . In: Gut: Annual Meeting of the British Association for the Study of the Liver. 2003, 缅北禁地 upon Tyne, UK: BMJ Group.
  • Perrow KA, Taylor JJ, James OFW, Bassendine MF, Jones DEJ, Donaldson PT. . In: Gut: Annual Meeting of the British Association for the Study of the Liver. 2003, 缅北禁地 upon Tyne, UK: BMJ Group.
  • Nicholls KA, Saxby BK, Harrington F, James OFW, Ford GA. . In: Journal of Hypertension: 13th European Meeting on Hypertension. 2003, Milan, Italy: Lippincott Williams & Wilkins, Ltd.
  • Prince M, Chetwynd AC, Craig WL, Metcalfe JV, James OFW. . In: Gut: Annual Meeting of the British Association for the Study of the Liver. 2003, 缅北禁地 upon Tyne, UK: BMJ Group.
  • Prince M, Mitchison HC, Ashley D, Burke DA, Edwards M, Bramble MG, James OF, Jones DE. . In: Hepatology: 53rd Annual Meeting of the Association for the Study of Liver Diseases. 2002, Boston, Massachusetts, USA: John Wiley & Sons, Inc.
  • Baragiotta A, James OFW, Craig W, Mitchison H, Burke D, Bateson M, Trewby P, Macklon A, Bassendine MF. . Journal of Hepatology 2002, 36(s1), 261 abstract no. 942.
  • Perrow KA, Taylor JJ, James O, Bassendine M, Jones D, Donaldson P. . In: Hepatology: 53rd Annual Meeting of the Association for the Study of Liver Diseases. 2002, Boston, Massachusetts, USA: John Wiley & Sons, Inc.
  • Degl'Innocenti A, Elmfeldt D, Hansson L, Breteler M, James O, Lithell H, Olofsson B, Skoog I, Trenkwalder P, Zanchetti A, Wiklund I. . Blood Pressure 2002, 11(3), 157-165.
  • Prince M, Chetwynd A, Craig W, Metcalf J, James OF. . In: Hepatology: 53rd Annual Meeting of the Association for the Study of Liver Diseases. 2002, Boston, Massachusetts, USA: John Wiley & Sons, Inc.
  • James OFW. . In: Acta Gastro-Enterologica Belgica: 6th Winter Meeting of the BASL. 2002, Charleroi, Pennsylvania, USA: Universa Press.
  • Harbison J, Ford GA, James OFW, Gibson GJ. . QJM 2002, 95(11), 741-747.
  • Watt FE, Bassendine MF, James OFW, Jones DEJ. A population based study of autoimmunity in primary biliary cirrhosis (PBC) patients and their families: Evidence for a shared susceptibility. In: JOURNAL OF HEPATOLOGY. 2001.
  • Baragiotta AM, Craig W, James O, Mitchison H, Burke D, Bateson M, Trewby P, Macklon A. . In: Journal of Hepatology. 2001, Elsevier BV.
  • Goldblatt J, James OFW, Jones DEJ. . In: Journal of Hepatology. 2001, Elsevier BV.
  • Baragiotta AM, Floreani A, Jones D, Venturi C, Agarwal K, James OFW, Donaldson PTD, Bassendine MF. . In: Journal of Hepatology. 2001, Elsevier BV.
  • Baragiotta M, Craig W, James O, Mitchison H, Burke D, Bateson M, Trewby P, Bassendine M. . In: Journal of Hepatology. 2001, Elsevier BV.
  • Prince MI, Chetwynd A, Diggle PJ, Metcalf JV, James OF. . In: Journal of Hepatology. 2001, Elsevier BV.
  • Baragiotta AM, Craig WL, James OFW, Mitchison HC, Burke DA, Bateson M, Trewby PN, Macklon AF, Bassendine MF, N England Autoimmune Liver Dis Grp. . In: British Society of Gastroenterology Annual Meeting. 2001, Glasgow, UK: BMJ Group.
  • Baragiotta AM, Floreani A, James O, Venturi C, Craggs A, Mega A, Jones D, Newton J, Bassendine M, Donaldson P. . In: Journal of Hepatology. 2001, Elsevier BV.
  • Newton JL, Rawlings D, Prince MI, James OFW, Bassendine MF, Jones DEJ. Osteoporosis is not a specific complication of primary biliary cirrhosis (PBC). In: JOURNAL OF HEPATOLOGY. 2000.
  • Goldblatt J, Taylor PJ, Lipman T, James OF, Jones DE. Prevalence of fatigue in a geographically based primary biliary cirrhosis population: Comparison with community controls. In: HEPATOLOGY. 2000.
  • Prince M, Metcalf J, Craig W, James OFW. Prognosis of primary biliary cirrhosis (PBC) in large unselected cohort. In: JOURNAL OF HEPATOLOGY. 2000.
  • Prince MI, Thomas SHL, James OFW, Hudson M. . In: Journal of Hepatology. 2000, Elsevier BV.
  • Rutter MD, Agarwal S, Record CO, Day CP, James OFW, Hudson M. Terlipressin for hepatorenal impairment in alcoholic hepatitis. In: Journal of Hepatology. 2000.
  • Prince MI, Howell D, Metcalf JV, Craig W, James OF. Time profile of symptom development and prognosis in 770 unselected patients with primary biliary cirrhosis (PBC). In: HEPATOLOGY. 2000.
  • Donaldson PT, Clare MC, Craig WL, Hudson M, Harrison P, Jones DE, Bassendine MF, James OF. Transforming growth cell factor beta-1 (TGFB-1) gene polymorphisms in primary sclerosing cholangitis and primary bilairy cirrhosis. In: Hepatology. 2000.
  • Prince MI, James OFW, Holland NP, Jones DEJ. . Journal of Hepatology 2000, 32(3), 368-373.
  • Watson JP, Jones DEJ, James OFW, Cann PA, Bramble MG. . Journal of Gastroenterology and Hepatology 1999, 14(10), 1034-1040.
  • Jones DEJ, James OFW, Portmann B, Burt AD, Williams R, Hudson M. . Hepatology 1999, 30(1), 53-57.
  • Chetwynd A, Diggle P, Jarnet M, Bhopal RS, Metcalf JV, James OFW. Evidence for spatial variation in risk and of spatial clustering in PBC. In: Hepatology. 1999, John Wiley & Sons, Inc.
  • Jones DEJ, Watt FE, Metcalf JV, Bassendine MF, James OFW. . Journal of Hepatology 1999, 30(3), 402-407.
  • Prince M, Ashley D, Edwards N, Mitchison H, Bramble M, James OF, Jones DE. Fatigue significantly impairs the quality of life of patients with primary biliary cirrhosis. In: Hepatology. 1999, John Wiley & Sons, Inc.
  • Neuberger J, James O. . Lancet 1999, 354(9190), 1636-1639.
  • Donaldson PT, Agarwal K, Heneghan MA, Jones DE, James OF, Bassendine MF. . In: Hepatology. 1999, John Wiley & Sons, Inc.
  • Metcalf JV, Bhopal RS, Gray JD, Howel D, James OF. . In: Hepatology. 1999, John Wiley & Sons, Inc.
  • Prince M, James OF, Jones DE. . In: Hepatology. 1999, John Wiley & Sons, Inc.
  • Metcalf JV, Newman W, Bhopal R, James OF. Men with PBC. In: Hepatology. 1999, John Wiley & Sons, Inc.
  • James OFW, Day CP. . Lancet 1999, 354(9186), 1299-1299.
  • James O, Day C. . Lancet 1999, 353(9165), 1634-1636.
  • Aithal GP, Alabdi BJ, Rose JDG, James OFW, Hudson M. . Liver 1999, 19(4), 343-347.
  • Harbison J, Rajan N, James OFW, Ford G, Gibson GJ. . In: Thorax. 1999, BMJ Group.
  • O'Mahony P, Rodgers H, Dobson R, James OFW, Thomson RG. . Journal of Public Health 1999, 21(2), 166-171.
  • O'Mahony PG, Thomson RG, Dobson R, Rodgers H, James OFW. . Journal of Public Health Medicine 1999, 21(2), 166-171.
  • Gani A, Rodgers H, Herd B, Murphy J, Dobson R, James O, Thomson RG. . In: European Stroke Conference. 1999, Venice, Italy: S. Karger AG.
  • Thomson RG, Gani A, Dobson R, Herd B, Murphy J, James O, Rodgers H. . In: 8th European Stroke Conference. 1999, Venice, Italy: S. Karger AG.
  • C. M. Fischbacher, J. V. Metcalf, D. Howel, R. Bhopal, D. E. Jones and O. F. W. James. A pilot case control study of possible risk factors for primary biliary cirrhosis (PBC). Hepatology 1998, 28, 1511.
  • J. Metcalf, R. Bhopal, J. Howel, W. Newman and O. F. W. James. A true clinical profile of primary bililary cirrhosis (PBC). Gut 1998, 42, TW120.
  • D. Nylander, C. P. Day and O. F. W. James. Alcoholic liver disease in the UK - Plus ca change. Gut 1998, 42, TW111.
  • J. P. Watson, P. A. Cann, M. G. Bramble, O. F. W. James and D. E. J. Jones. Antioxidant therapy for the symptomatic treatment of primary biliary cirrhosis: A pilot study. Gastroenterology 1998, 114, L0677.
  • M. I. Prince, W. L. Newman, O. F. W. James and D. E. J. Jones. Anti-smooth muscle antibody (SMA) positive AMA positive primary biliary cirrhosis: A distinct form of disease with hepatitis like features?. Hepatology 1998, 28, 1517.
  • D. E. J. Jones, F. E. Watt, J. V. Metcalf, M. F. Bassendine and O. F. W. James. Familial primary biliary cirrhosis: Guidance for clinical practice and the study of genetic susceptibility to disease. Hepatology 1998, 28, 919.
  • M. I. Prince, O. F. W. James and D. E. J. Jones. Fatigue in patients with primary biliary cirrhosis: Validation of a fatigue severity score as a clinical and research tool. Hepatology 1998, 28, 1518.
  • Newton JL, Jordan N, Oliver L, Strugala V, Pearson J, James OFW, Allen A. . Gut 1998, 43(4), 470-475.
  • C. P. Day and O. F. W. James. Hepatic steatosis: Innocent bystander or guilty party?. Hepatology 1998, 27, 1463-1466.
  • D. Howel, J. Metcalf and O. F. W. James. Is cancer commoner in primary biliary cirrhosis (PBC)?. Hepatology 1998, 28, 1510.
  • O'Mahony PG, Rodgers H, Thomson RG, Dobson R, James OFW. . Age and Ageing 1998, 27(1), 19-22.
  • O. F. W. James and C. P. Day. Non-alcoholic steatohepatitis (NASH): a disease of emerging identity and importance. Journal of Hepatology 1998, 29, 495-501.
  • Brown AJM, James OFW. . Alimentary Pharmacology and Therapeutics 1998, 12(2), 141-145.
  • J. Metcalf, R. Bhopal, J. Howel, M. Myszor and O. F. W. James. PBC: Increased incidence and prevalence together with geographical variation in one UK region. Gut 1998, 42, TW121.
  • T. M. Kourah, G. M. Amer, S. Elliott, C. Oates, O. F. W. James and M. Hudson. Post exercise induced changes in portal blood flow vary according to etiology and severity of liver disease. Hepatology 1998, 28, 120.
  • J. L. Newton, D. E. J. Jones, J. V. Metcalf, A. D. Burt, M. F. Bassendine and O. F. W. James. Primary biliary cirrhosis in the elderly: Increased liver related mortality despite similar clinical features at presentation. Hepatology 1998, 28, 1512.
  • C. P. Day and O. F. W. James. Steatohepatitis: A tale of two "hits"?. Gastroenterology 1998, 114, 842-845.
  • B. C. Smith and O. F. W. James. The failing malignant liver. Gut 1998, 42, 454-455.
  • J. L. Newton, D. E. J. Jones, J. V. Metcalf, A. D. Burt, M. F. Bassendine and O. F. W. James. The presentation of Primary Biliary Cirrhosis in the elderly. Gastroenterology 1998, 114, L0462.
  • P. G. O'Mahony, H. Rodgers, R. G. Thomson, R. Dobson and O. F. W. James. The use of the Short Form (SF)-36 questionnaire for older adults - Reply. Age and Ageing 1998, 27, 757-758.
  • J. Newton, N. Jordan, J. Pearson, A. Allen and O. F. W. James. Thinning of the adherent gastric antral and duodenal mucus gel layer in H-pylori positive subjects with advancing age. Gut 1998, 42, TF320.
  • S. A. Jenkins, R. Shields, M. Davies, E. Elias, A. J. Turnbull, M. F. Bassendine, O. F. W. James, J. P. Iredale, S. K. Vyas, M. J. P. Arthur, A. N. Kingsnorth and R. Sutton. A multicentre randomised trial comparing octreotide and injection sclerotherapy in the management and outcome of acute variceal haemorrhage. Gut 1997, 41, 526-533.
  • P. G. Omahony, R. G. Thomson, H. Rodgers, R. Dobson and O. F. W. James. Accuracy of the family health services authority register in 缅北禁地 upon Tyne, UK as a sampling frame for population studies. Journal of Epidemiology and Community Health 1997, 51, 206-207.
  • Farthing M., James O.F.W. Aging and the ailmentary tract (Editorial). Gut 1997, 41, 421.
  • J. Newton, N. Jordan, G. Williams, J. Pearson, A. Allen and O. James. Changes in the adherent gastric mucus get layer in H-pylori infected older subjects. Journal of the American Geriatrics Society 1997, 45, A11-A11.
  • J. Newton, V. Strugala, G. Williams, J. Pearson, O. James and A. Allen. Changes in the structure of the adherent gastric mucus gel layer in Helicobacter pylori infected human subjects. Gastroenterology 1997, 112, A234-A234.
  • D. E. J. Jones, J. V. Metcalf, J. D. Collier, M. F. Bassendine and O. F. W. James. Hepatocellular carcinoma in primary biliary cirrhosis and its impact on outcomes. Hepatology 1997, 26, 1138-1142.
  • J. V. Metcalf, R. S. Bhopal, J. Gray, D. Howel and O. F. W. James. Incidence and prevalence of primary biliary cirrhosis in the city of 缅北禁地 upon Tyne, England. International Journal of Epidemiology 1997, 26, 830-836.
  • J. Newton, N. Jordan, G. Williams, J. Pearson, O. James and A. Allen. Only Helicobacter pylori infection with gastric atrophy leads to thinning of the adherent gastric mucus gel layer in man. Gastroenterology 1997, 112, A235-A235.
  • B. C. Smith, M. F. Bassendine, C. P. Day, O. F. W. James, C. O. Record and M. Hudson. Outcome and referral of paracetemol (acetaminophen) overdose - Impact of a new regional liver transplant unit. Hepatology 1997, 26, 910-910.
  • O. F. W. James. Parenchymal liver disease in the elderly. Gut 1997, 41, 430-432.
  • O'Mahony PG, Rodgers H, Thomson RG, Dobson R, James OFW. . Clinical Rehabilitation 1997, 11(1), 68-72.
  • D. E. J. Jones, J. Devlin, O. F. W. James, R. Williams and M. Hudson. The development of autoimmune hepatitis post liver transplantation: A potential role for MHC class I. Hepatology 1997, 26, 448-448.
  • J. Newton, G. Williams, J. Pearson, O. James and A. Allen. The effect of Helicobacter pylori infection upon 24 hour pepsin activity in human subjects. Gastroenterology 1997, 112, A234-A234.
  • J. Metcalf and O. James. The geoepidemiology of primary biliary cirrhosis. Seminars in Liver Disease 1997, 17, 13-22.
  • C. J. Rees, J. D. Rose, C. O. Record, C. P. Day, M. F. Bassendine, O. F. James and M. Hudson. Transjugular intrahepatic portosystemic shunt: a limited role in refractory ascites. European Journal of Gastroenterology & Hepatology 1997, 9, 969-973.
  • A. Brown and O. F. W. James. Cimetidine, ranitidine and omeprazole have no effect on peak blood ethanol concentration, first pass metabolism or area under tee time ethanol curve under 'real life' conditions. Hepatology 1996, 23, P103-P103.
  • V. vanderPol, H. Rodgers, P. Aitken, O. James and R. Curless. Does alcohol contribute to accident and emergency department attendance in elderly people?. Journal of Accident & Emergency Medicine 1996, 13, 258-260.
  • T. J. Aspray, L. T. Weaver, A. Prentice and O. F. W. James. Health screening of older people: A rural African experience. Journal of the American Geriatrics Society 1996, 44, 219-220.
  • A. M. Brind, J. P. Watson, O. F. W. James and M. F. Bassendine. Hepatitis C virus infection in the elderly. Qjm-Monthly Journal of the Association of Physicians 1996, 89, 291-296.
  • Reeves HL, Manas DM, Bassendine MF, Hudson M, James OFW, Mirza DF, Record CO, Talbot D, Thick M, Day CP. . Hepatology 1996, 24(4 Part 2 Suppl. S), 208.
  • J. L. Newton, A. D. Burt, J. B. Park, J. Mathew, M. F. Bassendine and O. F. W. James. Is the new international diagnostic scoring system for autoimmune hepatitis too rigid?. Hepatology 1996, 24, 434-434.
  • C. P. Day, E. Gilvarry, T. J. Butler and O. F. W. James. Moderate alcohol intake is not deleterious in patients with alcoholic liver disease. Hepatology 1996, 24, 1268-1268.
  • J. V. Metcalf, H. C. Mitchison, J. M. Palmer, D. E. Jones, M. F. Bassendine and O. F. W. James. Natural history of early primary biliary cirrhosis. Lancet 1996, 348, 1399-1402.
  • K. E. Orr, D. M. Manas, P. Gibbs, F. K. Gould, O. F. W. James, M. Hudson, M. F. Bassendine, C. O. Record and M. G. Thick. Piperacillin/tazobactam and oral nonabsorbable antibiotics as prophylaxis in liver transplantation. Hepatology 1996, 23, P205-P205.
  • J. V. Metcalf, D. Howel, O. F. W. James and R. Bhopal. Primary biliary cirrhosis: Epidemiology helping the clinician - Epidemiology improves our knowledge of disease. British Medical Journal 1996, 312, 1181-1182.
  • D. M. Manas, D. R. D. Roberts, D. W. Heaviside, S. Chaudhry, K. Tocewicz, M. Hudson, P. Bayly, M. Thick, J. Dark and O. F. W. James. Sequential coronary artery bypass grafting and orthotopic liver transplantation: A case report. Clinical Transplantation 1996, 10, 320-322.
  • E. M. G. Phillips, P. H. Baylis and O. F. W. James. The metabolic clearance rate of AVP is altered in cirrhosis. Hepatology 1996, 23, P213-P213.
  • M. Hudson, J. Rose, O. F. W. James and M. F. Bassendine. Transjugular intrahepatic portosystemic shunting (TIPS) for refractory ascites. Hepatology 1996, 23, T25-T25.
  • J. V. Metcalf and O. F. W. James. Vascular and autoimmune disease ''associations'' with PBC. The best evidence available. Hepatology 1996, 24, 168-168.
  • Davis M, Mendelow AD, Perry RH, Chambers IR, James OFW. . Stroke 1995, 26(6), 1072-1078.
  • M. R. Teli, O. F. W. James, A. D. Burt, M. K. Bennett and C. P. Day. The natural history of nonalcoholic fatty liver: A follow-up study. Hepatology 1995, 22, 1714-1719.
  • Davis M, Mendelow AD, Perry RH, Chambers IR, James OFW. . In: Brain Edema IX. Vienna: Springer, 1994, pp.282-284.