缅北禁地

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Staff Profile

Professor Peter Blain

Emeritus Professor

  • Telephone: +44 (0) 191 208 7195
  • Fax: +44 (0) 191 208 6442
  • Address: Translational and Clinical Research Institute
    Faculty of Medical Sciences
    缅北禁地
    NE2 4AA
Background

Introduction

My research experience has been predominantly in medical toxicology with a specific interest in clinical neurotoxicology.  I  established a joint Medical Toxicology Research Centre with the Health Protection Agency in 2005 with a focus on biomarkers and toxic mechanisms, susceptibility factors and variability of toxic effects, and chronic and delayed health effects.  Subsequently, i received a grant of £6M in 2014 over 6 years from the NIHR for a HPRU in Chemical and Radiation Threats and Hazards.

Publications
  • Haslam JD, Russell P, Hill S, Emmett SR, Blain PG. . British Journal of Anaesthesia 2022, 128(2), e200-e205.
  • Leitch AC, Ibrahim I, Abdelghany TM, Charlton A, Roper C, Vidler D, Palmer JM, Wilson C, Jones DE, Blain PG, Wright MC. . Toxicology 2021, 459, 152854.
  • Young GR, Abdelghany TM, Leitch AC, Dunn MP, Blain PG, Lanyon C, Wright MC. . PLoS ONE 2020, 15(3), 0229745.
  • Emmett SR, Blain PG. . Medicine 2020, 48(3), 182-184.
  • Thompson A, Dunn M, Jefferson R, Dissanayake K, Reed F, Gregson R, Greenhalgh S, Clutton RE, Blain PG, Thomas SHL, Eddleston M. . Clinical Toxicology 2020, 58(3), 190-200.
  • Leitch AC, Abdelghany TM, Charlton A, Grigalyte J, Oakley F, Borthwick LA, Reed L, Knox A, Reilly WJ, Agius L, Blain PG, Wright MC. . Ecotoxicology and Environmental Safety 2020, 202, 110902.
  • Leitch AC, Abdelghany TM, Probert PM, Dunn MP, Meyer SK, Palmer JM, Cooke MP, Blake LI, Morse K, Rosenmai AK, Oskarsson A, Bates L, Figueiredo RS, Ibrahim I, Wilson C, Abdelkader NF, Jones DE, Blain PG, Wright MC. . Food and Chemical Toxicology 2020, 136, 111069.
  • Heslop DJ, Blain PG. . Intelligence and National Security 2020, 35(4), 539-555.
  • Meyer SK, Dunn M, Vidler DS, Porter A, Blain PG, Jowsey PA. . The FASEB Journal 2019, 323(2), ePub ahead of Print.
  • Keane PC, Hanson PS, Patterson L, Blain PG, Hepplewhite P, Khundakar AA, Judge SJ, Kahle PJ, LeBeau FEN, Morris CM. . Neuroscience Letters 2019, 711, 134437.
  • Khateri S, Balali-Mood M, Blain P, Williams F, Jowsey P, Soroush MR, Behravan E, Sadeghi M. . Toxicology Letters 2018, 293, 67-72.
  • Probert PM, Leitch AC, Dunn MP, Meyer SK, Palmer JM, Abdelghany TM, Lakey AF, Cooke MP, Talbot H, Wills C, McFarlane W, Blake LI, Rosenmai AK, Oskarsson A, Figueiredo R, Wilson C, Kass GE, Jones DE, Blain PG, Wright MC. . Journal of Hepatology 2018, 69(5), 1123-1135.
  • Nisar R, Hanson PS, Keane PC, He L, Taylor R, Blain PG, Morris CM. . Reactive Oxygen Species 2018, 6(18), 428-444.
  • Behravan E, Moallem SA, Kalalinia F, Ahmadimanesh M, Blain P, Jowsey P, Khateri S, Forghanifard MM, BalaliMood M. . Mutation Research/Genetic Toxicology and Environmental Mutagenesis 2018, 834, 1-5.
  • Leitch AC, Lakey AF, Hotham WE, Agius L, Kass GE, Blain PG, Wright MC. . Biochemical and Biophysical Research Communications 2018, 503(3), 2167-2178.
  • Khundakar AA, Hanson PS, Erskine D, Lax NZ, Roscamp J, Karyka E, Tsefou E, Singh P, Cockell SJ, Gribben A, Ramsay L, Blain PJ, Mosimann UP, Lett DJ, Elstner M, Turnbull DM, Xiang CC, Brownstein MJ, O'Brien JT, Taylor JP, Attems J, Thomas AJ, McKeith IG, Morris CM. . Acta Neuropathologica Communications 2016, 4, 66.
  • Langlands H, Blain PG, Jowsey PA. . PLoS One 2016, 11(5), e0155056.
  • Judge SJ, Savy CY, Campbell M, Dodds R, Gomes LK, Laws G, Watson A, Blain PG, Morris CM, Gartside SE. . Chemico-Biological Interactions 2016, 245, 82-89.
  • Probert PME, Meyer SK, Alsaeedi F, Axon AA, Fairhall EA, Wallace K, Charles M, Oakley F, Jowsey PA, Blain PG, Wright MC. . Toxicology Research 2015, 4(2), 203-222.
  • Jowsey PA, Blain PG. . Toxicology Letters 2015, 232(2), 413-421.
  • Nisar R, Hanson PS, He L, Taylor RW, Blain PG, Morris CM. . Archives of Toxicology 2015, 89(10), 1811-1825.
  • Savy CY, Fitchett AE, McQuade R, Gartside SE, Morris CM, Blain PG, Judge SJ. . Neurotoxicology 2015, 50, 149-156.
  • Hill SL, Thomas SHL, Flecknell PA, Thomas AA, Morris CM, Henderson D, Dunn M, Blain PG. . Emergency Medicine Journal 2015, 32(8), 626-631.
  • Amer AO, Probert PM, Dunn M, Knight M, Vallance AE, Flecknell PA, Oakley F, Cameron I, White SA, Blain PG, Wright MC. . PLoS ONE 2015, 10(8), e0136173.
  • Jowsey PA, Blain PG. . Biochemical Journal 2014.
  • Skamarauskas JT, Oakley F, Smith FE, Bawn C, Dunn M, Vidler DS, Clemence M, Blain PG, Taylor R, Gamcsik MP, Thelwall PE. . Hepatology 2014, 59(6), 2321-2330.
  • Moore CA, Wilkinson SC, Blain PG, Dunn M, Aust GA, Williams FM. . Toxicology Letters 2014, 229(1), 66-27.
  • Meyer S, Axon A, Jowsey P, Williams F, Blain P, Wright M. . In: 50th Congress of the European Societies of Toxicology (EUROTOX). 2014, Edinburgh: Elsevier Ireland.
  • Moore CA, Wilkinson SC, Blain PG, Dunn M, Aust GA, Williams FM. . Toxicology Letters 2014, 229(1), 257-264.
  • Jowsey PA, Blain PG. . Toxicology Letters 2014, 230(3), 393-401.
  • Blakey DH, Lafontaine M, Lavigne J, Sokolowski D, Philippe JM, Sapori JM, Biederbick W, Horre R, Marzi WB, Kondo H, Kuroki Y, Namera A, Okumura T, Yamamoto M, Yashiki M, Blain PG, Russell DR, Cibulsky SM, Jett DA, Global Health Security Initiative. . BMC Public Health 2013, 13, 253.
  • Sidaginamale RP, Joyce TJ, Lord JK, Jefferson R, Blain PG, Nargol VF, Langton D. . Bone and Joint Research 2013, 2(5), 84-95.
  • Behravan E, Moallem SA, Khateri S, Maraghi E, Jowsey P, Blain PG, Balali-Mood M. . Journal of Research in Medical Sciences 2013, 18(3), 239-244.
  • Hill SL, Doris T, Gurung S, Katebe S, Lomas A, Dunn M, Blain P, Thomas SHL. . Clinical Toxicology 2013, 51(6), 487-492.
  • Baron AW, Rushton SP, Rens N, Morris CM, Blain PG, Judge SJ. . NeuroToxicology 2013, 34, 1-8.
  • Langton DJ, Sidaginamale R, Joyce TJ, Natu S, Blain P, Jefferson RD, Rushton S, Nargol AVF. . British Medical Journal Open 2013, 3(3), 1-13.
  • Blain PG. . In: 17th World Congress of the International Society on Toxinology. 2012, Honolulu, Hawaii, USA: Pergamon.
  • Hanson PS, Blain PG, Mulligan J, Morris CM. . In: Health Protection. 2012, University of Warwick.
  • Jowsey PJ, Williams FM, Blain PG. . Toxicology Letters 2012, 209(1), 1-10.
  • Kurzawa-Akanbi M, Hanson PS, Blain PG, Lett DJ, McKeith IG, Chinnery PF, Morris CM. . Journal of Neurochemistry 2012, 123(2), 298-309.
  • Murray DM, Eddleston M, Thomas S, Jefferson RD, Thompson A, Dunn M, Vidler DS, Clutton E, Blain PG. . Annals of Emergency Medicine 2012, 60(4), 424-430.
  • Axon A, May FEB, Gaughan LE, Williams FM, Blain PG, Wright MC. . Toxicology 2012, 298(1-3), 40-51.
  • Keane PC, Judge SJ, Blain PG, Morris CM. . In: Annual Congress of The British Toxicology Society. 2011, Durham: Elsevier Ireland Ltd.
  • Savy CY, Morris CM, Blain PG, Judge SJ. . Toxicology 2011, 290(2-3), 116.
  • Keane PC, Kurzawa M, Blain PG, Morris CM. . Parkinson's Disease 2011, 2011, 716871.
  • Baron AW, Steeg R, Morris CM, Blain PG, Judge SJ. . In: Toxicology: Annual Congress of The British Toxicology Society. 2011, Durham, UK: Elsevier Ireland Ltd.
  • Blain PG, Jefferson RD. . In: Baxter, P., Aw, T-C., Cockcroft, A., Durrington, P., Harrington, J.M, ed. Hunter's Diseases of Occupations. London, UK: Hodder & Stroughton, 2010, pp.127-140.
  • Russell D, Blaine PG, Rice P. . Emergency Medicine Journal 2006, 23(6), 421-424.
  • Gage VR, Blain PG, Leathart JBS, Daly AK, Williams FM. . In: Annual Congress of the British Toxicology Society. 2004, Edinburgh, Scotland: Toxicology: Elsevier.
  • Harris JB, Blain PG. . Journal of Neurology, Neurosurgery and Psychiatry 2004, 75, iii29-iii34.
  • Harris JB, Blain PG. . Neurology in Practice 2004, 75(suppl. 3), iii29-iii34.
  • Blain PG. . Toxicologic Pathology 2003, 31(2), 254-257.
  • Blain PG. . Toxicological Reviews 2003, 22(2), 103-110.
  • Howel D, O'Brien S, Murphy E, Chinn DJ, McCrone C, French JM, Blain PG. . Occupational Medicine 2001, 51(5), 336-342.
  • De Blaquiere GE, Waters L, Blain PG, Williams FM. . Toxicology and Applied Pharmacology 2000, 166(2), 81-91.
  • Mutch E, Blain PG, Williams FM. . In: International Symposium on Health Aspects of Environmental and Occupational Pesticide Exposure. 1999, Düsseldorf, Germany: Elsevier.
  • C. S. Roper, D. Howes, P. G. Blain and F. M. Williams. A comparison of the absorption of a series of ethoxylates through rat skin in vitro. Toxicology in Vitro 1998, 12, 57-65.
  • G. E. de Blaquiere, F. M. Williams, P. G. Blain and S. S. Kelly. A comparison of the electrophysiological effects of two organophosphates, mipafox and ecothiopate, on mouse limb muscles. Toxicology and Applied Pharmacology 1998, 150, 350-360.
  • Blain P.G. et al. Consideration of short-term carcinogenicity tests using transgenic mouse models. Mutation Research-Fundamental and Moelcular Mechanisms of Mutagenesis 1998, 16, 138-145.
  • P. G. Blain, J. M. Battershill, S. Venitt, C. C. Cooper and R. J. Fielder. Consideration of short-term carcinogenicity tests using transgenic mouse models. Mutation Research-Fundamental and Molecular Mechanisms of Mutagenesis 1998, 403, 259-263.
  • Dick, I.P., Blain, P.G. and Williams, Faith M. Development of structure-activity relationships useful to risk assessment utilising human skin in in vitro systems. Perspectives of Percutaneous Penetration STS Publishing, Cardiff Ed Brain, James and Waters 1998, 5b, 76-79.
  • Blain PG, Loughney E. . Occupational and Environmental Medicine 1998, 55(6), 434-434.
  • Dick, I.P., Blain, P.G. and Williams, Faith M. Useful of animal models in predicting human skin permeability for a series of chemicals of different liphilicities. Perspectives of Percutaneous Penetration STS Publishing, Cardiff Ed Brain, James and Waters 1998, 5b, 73-75.
  • S. J. Crosbie, P. G. Blain and F. M. Williams. An investigation into the role of rat skeletal muscle as a site for xenobiotic metabolism using microsomes and isolated cells. Human & Experimental Toxicology 1997, 16, 138-145.
  • S. S. Kelly, G. E. deBlaquiere, F. M. Williams and P. G. Blain. Effects of multiple doses organophosphates an evoked potentials in mouse diaphragm. Human & Experimental Toxicology 1997, 16, 72-78.
  • S. J. Crosbie, P. G. Blain and F. M. Williams. Metabolism of n-hexane by rat liver and extrahepatic tissues and the effect of cytochrome P-450 inducers. Human & Experimental Toxicology 1997, 16, 131-137.
  • C. S. Roper, D. Howes, P. G. Blain and F. M. Williams. Percutaneous penetration of 2-phenoxyethanol through rat and human skin. Food and Chemical Toxicology 1997, 35, 1009-1016.
  • Azari MR, Edwards JW, Williams FM and Blain PG. Potential biomarkers of exposure and effect among glass craftsmen and braziers exposed to nitrogen oxides. Biomarkers 1997, 2, 349-354.
  • Hatjian B.A., Edwards J.W., Harrison J., Williams F.M. and Blain P.G. Risk assessment of occupational exposure to bitumen fumes in the road paving and roofing industries. Journal of Occupational Health and Safety - Australia and New Zealand 1997, 13, 65-78.
  • F. M. Williams, C. Charlton, G. E. deBlaquiere, E. Mutch, S. S. Kelly and P. G. Blain. The effects of multiple low doses of organophosphates on target enzymes in brain and diaphragm in the mouse. Human & Experimental Toxicology 1997, 16, 67-71.
  • I. P. Dick, P. G. Blain and F. M. Williams. The percutaneous absorption and skin distribution of lindane in man. I. In vivo studies. Human & Experimental Toxicology 1997, 16, 645-651.
  • Dick IP, Blain PG, Williams FM. . Human and Experimental Toxicology 1997, 16(11), 652-657.
  • M. R. Azari, F. M. Williams, J. Kirby, P. Kelly, J. W. Edwards and P. G. Blain. Effects of nitrogen oxides on natural killer cells in glass craftsmen and braziers. Occupational and Environmental Medicine 1996, 53, 248-251.
  • Langford AM, Hobbs MJ, Upshall DG, Blain PG, Williams FM. . Human & Experimental Toxicology 1996, 15(8), 619-624.
  • P. G. Blain. Variability in susceptibility of the nervous system to toxic insult. Environmental Toxicology and Pharmacology 1996, 2, 131-133.
  • E. Mutch, S. S. Kelly, P. G. Blain and F. M. Williams. Comparative studies of two organophosphorus compounds in the mouse. Toxicology Letters 1995, 81, 45-53.
  • Kelly, S.S., Mutch, E, Williams, Faith M. and Blain, P.G. Electrophysiological changes in the neuromuscular system and biochemical effects following single doses of organophosphates in the mouse. Arch. Toxicol 1994, 68, 459-466.
  • Williams, F.M., Mutch, E and Blain P.G. Paraoxonase distribution in Caucasian males. Chem. Biol. Interact 1993, 87, 155-160.
  • Mutch E, Blain PG, Williams FM. . Human & Experimental Toxicology 1992, 11(2), 109-116.
  • BLAIN PG, LANE RJM, BATEMAN DN, RAWLINS MD. OPIATE-INDUCED RHABDOMYOLYSIS. In: HUMAN TOXICOLOGY. 1985.
  • RAWLINS MD, BLAIN PG, ROBERTS DF. SAMPLING FROM THE ADULT-POPULATION FOR PHARMACOKINETIC AND PHARMACOGENETIC STUDIES - REPLY. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY 1984, 18(4), 654-655.
  • BLAIN PG, LANE RJM. DIHYDROCODEINE OVERDOSE TREATED WITH NALOXONE INFUSION. BRITISH MEDICAL JOURNAL 1983, 287(6404), 1547-1547.
  • BLAIN PG, LANE RJM. DRUGS AND MUSCLE. ADVERSE DRUG REACTIONS AND TOXICOLOGICAL REVIEWS 1983, 2(1), 1-24.
  • WOODHOUSE KW, BLAIN PG. SOME ORGAN-SPECIFIC ADVERSE REACTIONS TO CYTO-TOXIC DRUGS. ADVERSE DRUG REACTIONS AND TOXICOLOGICAL REVIEWS 1983, 2(2), 123-143.
  • JOHNSTON DG, ALBERTI KGMM, WRIGHT R, BLAIN PG. GLYCEROL CLEARANCE IN ALCOHOLIC LIVER-DISEASE. GUT 1982, 23(4), 257-264.
  • BLAIN PG, MUCKLOW JC, RAWLINS MD, ROBERTS DF, ROUTLEDGE PA, SHAND DG. DETERMINANTS OF PLASMA ALPHA-1 ACID GLYCOPROTEIN CONCENTRATIONS IN HEALTH. In: BRITISH JOURNAL OF CLINICAL PHARMACOLOGY. 1981.
  • WHALLEY LJ, BLAIN PG, PRIME JK. HALOPERIDOL SECRETED IN BREAST-MILK. BRITISH MEDICAL JOURNAL 1981, 282(6278), 1746-1747.
  • BLAIN PG. HALOPERIDOL SECRETED IN BREAST-MILK - REPLY. BRITISH MEDICAL JOURNAL 1981, 283(6285), 230-230.
  • BLAIN PG, MUCKLOW JC, BACON CJ, RAWLINS MD. PHARMACOKINETICS OF PHENYTOIN IN CHILDREN. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY 1981, 12(5), 659-661.
  • BATEMAN DN, BLAIN PG. DOPAMINE-RECEPTOR BLOCKADE AND TARDIVE-DYSKINESIA. LANCET 1979, 2(8143), 641-641.