缅北禁地

Dr White is a cell and molecular biologists. His career first focussed on bringing benefit to health through advances in gene therapy, particularly focussing on cardiovascular gene therapy, followed by a shift to study cardiovascular biology in more detail. Dr White has in depth knowledge in endothelial biology and biomechanics as well as vascular biology and processes that promote atherosclerosis and progression to clinical sequalae such as heart attacks.

Previous posts: 

Reader in Cardiovascular Pathology, Manchester Metropolitan University. (1/10/2016-30/6/23)

BHF-funded Research Fellow (CH95/001), Bristol Heart Institute, University of Bristol. (1/1/2007 – 30/9/2016)

British Heart Foundation Intermediate Fellow, Bristol Heart Institute (1/1/2004-31/12/2006).

Postdoctoral Scientist, Bristol Heart Institute (1/12/1997-31/12/2003)

Education:          

University of Warwick. Class 2(i), B.Sc. (Hons) (1994) Microbiology and Virology.

University of Oxford. D.Phil., (1998). Ex-vivo keratinocyte gene therapy.

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I am a molecular cell biologist focussing on the mechanisms that cause heart attacks, predominantly endothelial erosion, which is the trigger of ~25% of heart attacks. I have a particular expertise in endothelial biology, biomechanics, endothelial dysfunction and physiological cell models to allow the study of endothelial responses overlying atherosclerotic plaques. Current projects include deciphering the molecular pathways involved in driving plaque erosion, multi-omic analysis of adhesome signalling, understanding the molecular drivers of disease from GWAS & EWAS studies, the creation of a CV risk detection platform E-Sense, and health data mining for novel digital patterns of CV risk, aided by a multidisciplinary team of friends and collaborators across the globe.

I am part of the team delivering training for future NHS scientists through the Scientist Training Programme (STP) on our MSC Clinical Science, with an intake of over 120 students per year. Within the MSc Clin Sci course, I am module lead for MSC8003 and co module lead for MSC8004, providing teaching, assessments and support for the clinical projects, an integral component of this training programme. I also deliver lectures on first and second year teaching modules on the MSc Clin science programme (CVR8001 and CVR8008).

In addition, I contribute to teaching, assessments and marking on our MRes in Cardiovascular Health and Disease (MMB8037) and undergraduate 3rd year module 'Clinical Aging and Health' (BMS3017).

• Articles

  • Sakkers TR, Mili E, Winter H, Kapteijn D, Perry RN, Barbera N, Watts K, Dias IR, Meteva D, Wesseling M, Mol BM, de Borst GJ, de Kleijn DPV, van der Laan SW, Civelek M, White SJ, Maegdefessel L, Mayr M, Pasterkamp G, Benavente ED, den Ruijter HM. . Circulation Research 2026, 138, e327624.
  • Luo X, Li J, Chen Y, Weng X, Bao B, Bai X, Lv Y, Zhang S, Zhu X, Xu B, Zhao C, Zeng M, Wu T, Sun Q, Wang S, Liu M, Johnson T, White SJ, Libby P, Hu S, Yu B, Jia H. . JACC: Basic to Translational Science 2025, 10(8), 101283.
  • Bowley G, Irving S, Hoefer I, Wilkinson R, Pasterkamp G, Darwish HMS, White S, Francis SE, Chico T, Noel E, Serbanovic-Canic J, Evans PC. . Scientific Reports 2024, 14, 30130.
  • Wentzel JJ, Bos D, White SJ, van der Heiden K, Kavousi M, Evans PC. . Atherosclerosis 2024, 395, 117616.
  • Drysdale A, Blanco-Lopez M, White SJ, Unsworth AJ, Jones S. . International Journal of Molecular Sciences 2024, 25(2), 950.
  • Selvarajan I, Kiema M, Huang RT, Li J, Zhu J, Pölönen P, Örd T, Õunap K, Godiwala M, Golebiewski AK, Ravindran A, Mäklin K, Toropainen A, Stolze LK, Arce M, Magnusson PU, White S, Romanoski CE, Heinäniemi M, Laakkonen JP, Fang Y, Kaikkonen-Määttä M. . Arteriosclerosis, Thrombosis, and Vascular Biology 2024, 44(6), 1330-1345.
  • Zhang X, Han L, Sobeih T, Han L, Dempsey N, Lechareas S, Tridente A, Chen H, White S, Zhang D. . IEEE Journal of Biomedical and Health Informatics 2023, 27(2), 980-991.
  • Satta S, Beal R, Smith R, Luo X, Ferris GR, Langford-Smith A, Teasdale J, Ajime TT, SerrCrossed D SignCopyright J, Hazell G, Newby GS, Johnson JL, Kurinna S, Humphries MJ, Gayan-Ramirez G, Libby P, Degens H, Yu B, Johnson T, Alexander Y, Jia H, Newby AC, White SJ. . Cardiovascular Research 2023, 119(9), 1869-1882.
  • Wang S, Hu S, Luo X, Bao X, Li J, Liu M, Lv Y, Zhao C, Zeng M, Chen X, Unsworth A, Jones S, Johnson TW, White SJ, Jia H, Yu B. . eBioMedicine 2022, 78, 103964.
  • Corbin LJ, White SJ, Taylor AE, Williams CM, Taylor K, Van Den Bosch MT, Teasdale JE, Jones M, Bond M, Harper MT, Falk L, Groom A, Hazell GGJ, Paternoster L, Munafo MR, Nordestgaard BoG, Tybjaerg-Hansen A, Bojesen SE, Relton C, Min JL, Davey Smith G, Mumford AD, Poole AW, Timpson NJ. . Circulation Research 2022, 130(3), 384-400.
  • Qiu Y, Buffonge S, Ramnath R, Jenner S, Fawaz S, Arkill KP, Neal C, Verkade P, White SJ, Hezzell M, Salmon AHJ, Suleiman M-S, Welsh GI, Foster RR, Madeddu P, Satchell SC. . Diabetologia 2022, 65(5), 879-894.
  • Luo X, Weng X, Bao X, Bai X, Lv Y, Zhang S, Chen Y, Zhao C, Zeng M, Huang J, Xu B, Johnson TW, White SJ, Li J, Jia H, Yu B. . Redox Biology 2022, 57, 102511.
  • McElroy M, Kim Y, Niccoli G, Vergallo R, Langford-Smith A, Crea F, Gijsen F, Johnson T, Keshmiri A, White SJ. . Scientific Reports 2021, 11, 7253.

• Letter

  • Lin CMA, Tabaqchali HM, White S, Pratt AG, Isaacs JD, Cooles FAH. . Rheumatology Advances in Practice 2026, 10(1), rkaf145.

• Reviews

  • Spray L, Richardson G, Haendeler J, Altschmied J, Rumampouw V, Wallis SB, Georgiopoulos G, White S, Unsworth A, Stellos K, Tual-Chalot S, Spyridopoulos I. . Cell Reports Medicine 2025, 6(9), 102264.
  • Drysdale A, Unsworth AJ, White SJ, Jones S. . International Journal of Molecular Sciences 2023, 24(14), 11854.