缅北禁地

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Staff Profile

Dr Wezi Sendama

MRC Clinician Scientist

Background

Introduction

I am a clinician scientist with an interest in the mechanisms of the resolution of inflammation in the lungs, particularly in ageing.

I graduated from 缅北禁地 Medical School in 2011 and completed my Foundation and Core Medical Training in the Northern region. I undertook doctoral research at 缅北禁地 alongside my clinical specialty training in respiratory medicine. My PhD exploring the mechanisms of pulmonary inflammation in ageing and chronic lung disease was awarded in 2022. I was subsequently appointed as an NIHR Clinical Lecturer in Respiratory Medicine at 缅北禁地 to undertake further research with a focus on lung immunity.

I was awarded an MRC Clinician Scientist Fellowship in 2026 to investigate disordered inflammation in the lungs of older survivors of pneumonia. As well as leading this research, I see patients with interstitial lung diseases in my role as an Honorary Consultant in Respiratory Medicine at the Royal Victoria Infirmary.

Qualifications

MBBS, 缅北禁地, 2011

MRCP(UK), Royal College of Physicians, 2015

Specialty Certificate Examination in Respiratory Medicine, 2019

PhD, 缅北禁地, 2022

Postgraduate Certificate in Rare Lung Diseases, ERN-LUNG Academy, 2023

Other roles

Honorary Consultant Respiratory Physician, 缅北禁地 upon Tyne Hospitals NHS Foundation Trust

Member, MRCP(UK) Clinical Science Specialty Question Group

Associate editor, Journal of Cellular and Molecular Medicine

Early Career Group Editor-in-Training, American Journal of Respiratory and Critical Care Medicine

Research

I am part of the PRINCIPLE (Paediatric, Respiratory, INtensive Care, Immunity and PuLmonary Epithelium) Research Group. I have a research interest in the mechanisms of the resolution of inflammation in the lung, particularly in ageing and in critical illness.

The research programme supported by my MRC Clinician Scientist Fellowship seeks to understand the mechanisms by which inflammation resolves incompletely in the lungs of older people who survive pneumonia, and we aim to develop treatments to improve health outcomes for this group of patients.

I am a co-investigator on the , a study that seeks to explore the impact of inhaled sargramostim (GM-CSF) on the function of alveolar macrophages, a set of cells with an important role in lung inflammation and immunity.

I also investigate the roles of lung immune cells in the exposure-related interstitial lung disease hypersensitivity pneumonitis (HP).

Funding and prizes

MRC Clinician Scientist Fellowship: Inflammation resolution in older survivors of pneumonia, 2026-2031. £1.57m

EPSRC BIOREME Small Starter Grant, support for research visit to the Statistical Biophysics laboratory (Dr Aleksandra Walczak), École Normale Supérieure, Paris, 2025. £1,000

Google Cloud Academic Research Grant, T cell receptor repertoires in interstitial lung disease, 2024-2025. US$5,000

Medical Research Council Experimental Medicine grant: Key mechanisms underlying inhaled GM-CSF's enhancement of phagocytosis and bacterial clearance by human alveolar macrophages (researcher co-investigator; PI Prof John Simpson), 2022-2025. £1.24m

Royal Society of Medicine Respiratory Registrar Research Award, 2023. £100

Best Oral Presentation prize at 2020 NIHR 缅北禁地 BRC Trainee Showcase. £100

Wellcome Trust ISSF Broadening Our Horizons fund, to attend Next Generation Sequencing Data Analysis: A Practical Introduction bioinformatics workshop in Munich, 8-10 May 2019. £1,941

Publications

  • Articles

    • Sendama W, Funston W, Davidson RCH, Rostron AJ, Simpson AJ. . Computational and Structural Biotechnology Journal 2026, 35(1), 0002.
    • Ly KCH, Feriz AM, Isobe T, Vahidi A, Vaghari D, Rostron A, Londoño MQ, Mende N, Vijayabaskar MS, Moullet M, Foster AR, Graves E, Torabi F, Admane C, Horsfall D, Basurto-Lozada D, Stephenson E, Botting RA, Iskander D, Webb S, Goh I, Jafree DJ, Sturgess KHM, Scott J, Sendama W, Magnani L, Hannah R, Asadollahzadeh H, Holland A, Prete M, Simpson J, Roy A, Roberts I, Jardine L, Laurenti E, Trynka G, Wilson NK, Haniffa M, Göttgens B, Lotfollahi M. Predicting how perturbations reshape cellular trajectories with PerturbGen. bioRxiv 2026. In Preparation.
    • Lake CJ, Scott J, Ruchaud-Sparagano MH, Thompson JH, Dewar F, Yarova P, Funston W, Davidson RCH, Musgrave KM, Wright SE, Clement I, Roy AI, Sendama W, Powell J, Brooks D, Lin A, Davies K, Hellyer TP, Rostron AJ, Simpson AJ. . Thorax 2025, epub ahead of print.
    • Sendama W, Funston W, Rostron AJ, Simpson AJ. . American Journal of Respiratory and Critical Care Medicine 2023, 207(9), 1246-1249.
    • Musgrave KM, Scott J, Sendama W, Gardner AI, Dewar F, Lake CJ, Spronk HMH, van Oerle R, Visser M, ten Cate H, Kesteven P, Fuller A, McDonald D, Knill C, Hulme G, Filby A, Wright SE, Roy AI, Ruchaud-Sparagano M, Simpson AJ, Rostron AJ. . Thrombosis Research 2023, 228, 10-20.
    • Elcioglu ZC, Errington L, Metes B, Sendama W, Powell J, Simpson AJ, Rostron AJ, Hellyer TP. . BMC Infectious Diseases 2023, 23, 848.
    • Sendama W. . Ageing Research Reviews 2020, 57, 101000.
    • Sendama W. . Computational and Structural Biotechnology Journal 2020, 18, 3947-3949.
    • Sendama W, Musgrave KM. . The American Journal of Medicine 2018, 131(12), 1438-1443.
    • Sendama W, Shipley M. . Respiratory Medicine Case Reports 2015, 14, 47-48.
    • Sendama W. . Student BMJ 2010, 18.

  • Book Chapter

    • Sendama W, Simpson AJ, Ewan V. . In: Sam Janes, ed. Encyclopedia of Respiratory Medicine (2nd edition). Amsterdam, The Netherlands: Elsevier, 2022, pp.333-341.

  • Conference Proceedings (inc. Abstracts)

    • Rafique C, Mitchell D, Ewart J, Forrest I, Funston W, Palmer E, Sendama W, Simpson AJ, Wiscombe S. . In: British Thoracic Society Winter Meeting. 2024, London: BMJ Group.
    • Musgrave K, Scott J, Sendama W, Kesteven P, Ruchaud-Sparagano M, Rostron A, Simpson AJ. . In: 60th Annual Scientific Meeting of the British Society for Haematology. 2020, Birmingham, UK: Wiley.