缅北禁地

I am a clinical senior lecturer and honorary consultant neurologist. I am one of the key team members of the NHS Highly Specialised Service for Rare Mitochondrial Disorders.

Qualifications

MBChB (Hons), University of Aberdeen (2007)

MRCP (UK) (2011)

PhD, 缅北禁地 (2016)

MRCP (Neurology) (2021)

Membership

Association of British Neurologists (ABN)

European Academy of Neurology (EAN)

Ataxia Global Initiatives

Research Interests

Neurological manifestations and neurodegeneration are prominent in many mitochondrial diseases, and their clinical management is challenging. While promising novel compounds are emerging, the disease trajectory in different genotypes remain poorly investigated, imposing significant barriers of translation into clinical trials. My research interests focus on the following aspects:

1) Characterising ataxia in adult patients with mitochondrial disease and comparing with the other forms of genetic ataxia;

2) Understanding the natural history of stroke-like episodes (clinical, radiological, EEG and neuropathological aspects), the most devastating acute presentation for a subgroup of patients;

3) Conducting observational studies of specific phenotypes or genotypes associated with mitochondrial disease;

4) Developing clinical practice guidelines for adult patients in collaboration with colleagues within the NHS Highly Specialised Service for Rare Mitochondrial Disorders and external experts.

Undergraduate clinical teaching (Medicine and Surgery)

- Year 3 EoCP (Essential of Clinical Practice)

- Year 4 MOSLER examiner

Postgraduate

- Project supervisor for Master of Research (MRes) 

- Lecturer for Mitochondrial Biology & Medicine MRes module

- Deputy lead for Clinical Research Dissertation (e-learning) module

- Academic supervisor for Academic Foundation Programme (AFP)

• Bourke JP, Ng YS, Tynan M, Bates MGD, Mohiddin S, Turnbull D, Gorman GS. . Open Heart 2022, 9(1), e001819.
• Ng YS, Lax NZ, Blain AP, Erskine D, Baker MR, Polvikoski T, Thomas RH, Morris CM, Lai M, Whittaker RG, Gebbels A, Winder A, Hall J, Feeney C, Farrugia ME, Hirst C, Roberts M, Lawthom C, Chrysostomou A, Murphy K, Baird T, Maddison P, Duncan C, Poulton J, Nesbitt V, Hanna MG, Pitceathly RDS, Taylor RW, Blakely EL, Schaefer AM, Turnbull DM, McFarland R, Gorman GS. . Brain 2022, 145(2), 542-554.
• Stefanetti RJ, Ng YS, Errington L, Blain AP, McFarland R, Gorman GS. . Neurology 2022, 98(23), E2318-E2328.
• Lim AZ, Ng YS, Blain A, Jiminez-Moreno C, Alston CL, Nesbitt V, Simmons L, Santra S, Wassmer E, Blakely EL, Turnbull DM, Taylor RW, Gorman GS, McFarland R. . Annals of Neurology 2022, 91(1), 117-130.
• Houghton D, Ng YS, Jackson MA, Stefanetti R, Hynd P, Aogáin MM, Stewart CJ, Lamb CA, Bright A, Feeney C, Newman J, Turnbull DM, McFarland R, Blain AP, Gorman GS. . Gastro Hep Advances 2022, 1(4), 666-677.
• Bindoff LA, Brown DA, Gorman GS, Karaa A, Keshavan N, Lamperti C, Mancuso M, McFarland R, Ng YS, O'Callaghan M, Pitceathly RDS, Rahman S, Russel FGM, Schirris TJJ, Varhaug KN, De Vries MC. . Journal of Inherited Metabolic Disease 2021, 44(1), 6-7.
• Ng YS, Bindoff LA, Gorman GS, Klopstock T, Kornblum C, Mancuso M, McFarland R, Sue CM, Suomalainen A, Taylor RW, Thorburn DR, Turnbull DM. . The Lancet Neurology 2021, 20(7), 573-584.
• Gomes TMB, Ng YS, Pickett SJ, Turnbull DM, Vincent AE. . Human Molecular Genetics 2021, 30(R2), R245-R253.
• Lim AZ, Jones DM, Bates MGD, Schaefer AM, O'Sullivan J, Feeney C, Farrugia ME, Bourke JP, Turnbull DM, Gorman GS, McFarland R, Ng YS. . Open Heart 2021, 8(1), e001510.
• Ng YS, Baker MR. . The New England Journal of Medicine 2021, 384(2), 192-194.
• Hatton C, Reeve A, Lax NZ, Blain A, Ng YS, El-Agnaf O, Attems J, Taylor JP, Turnbull D, Erskine D. . Acta Neuropathologica Communications 2020, (8), 103.
• Cotta A, Alston CL, Baptista-Junior S, Paim JF, Carvalho E, Navarro MM, Appleton M, Ng YS, Valicek J, da-Cunha-Junior AL, Lima MI, de la Rocque Ferreira A, Takata RI, Hargreaves IP, Gorman GS, McFarland R, Pierre G, Taylor RW. . JIMD Reports 2020, 54(1), 45-53.
• Erskine D, Reeve AK, Polvikoski T, Schaefer AM, Taylor RW, Lax NZ, El-Agnaf O, Attems J, Gorman GS, Turnbull DM, Ng YS. . Acta Neuropathologica 2020, 139, 219-221.
• Stefanetti RJ, Blain A, Jimenez-Moreno C, Errington L, Ng YS, McFarland R, Turnbull DM, Newman J, Gorman GS. . Wellcome Open Research 2020, 5(84).
• Ng YS, Thompson K, Loher D, Hopton S, Falkous G, Hardy SA, Schaefer AM, Shaunak S, Roberts ME, Lilleker JB, Taylor RW. . Frontiers in Genetics 2020, 11, 24.
• Chapman J, Ng YS, Nicholls TJ. . Life 2020, 10(9), 164.
• Ng YS, Turnbull DM. . Practical Neurology 2020, 20(4), 260-261.
• Zierz CM, Baty K, Blakely EL, Hopton S, Falkous G, Schaefer AM, Hadjivassiliou M, Sarrigiannis PG, Ng YS, Taylor RW. . Journal of Clinical Medicine 2019, 8(6), 789.
• Boal RL, Ng YS, Pickett S, Schaefer AM, Feeney C, Bright A, Taylor RW, Turnbull DM, Gorman GS, Cheetham T. . Journal of Clinical Endocrinology and Metabolism 2019, 104(6), 2057-2066.
• Hayhurst H, de Coo IFM, Piekutowska-Abramczuk D, Alston CL, Sharma S, Thompson K, Rius R, He L, Hopton S, Ploski R, Ciara E, Lake NJ, Compton AG, Delatycki MB, Verrips A, Bonnen PE, Jones SA, Morris AA, Shakespeare D, Christodoulou J, Wesol-Kucharska D, Rokicki D, Smeets HJM, Pronicka E, Thorburn DR, Gorman GS, McFarland R, Taylor RW, Ng YS. . Annals of Clinical and Translational Neurology 2019, 6(3), 515-524.
• Pickett SJ, Blain A, Ng YS, Wilson IJ, Taylor RW, McFarland R, Turnbull DM, Gorman GS. . New England Journal of Medicine 2019, 380(20), 1971-1972.
• Braz LP, Ng YS, Gorman GS, Schafer AM, McFarland R, Taylor RW, Turnbull DM, Whittaker RG. . Neurology Clinical Practice 2021, 11(2), 97-104.
• Ng YS, Martikainen MH, Gorman GS, Blain A, Bugiardini E, Bunting A, Schaefer AM, Alston CL, Blakely EL, Sharma S, Hughes I, Lim A, de Goede C, McEntagart M, Spinty S, Horrocks I, Roberts M, Woodward CE, Chinnery PF, Horvath R, Nesbitt V, Fratter C, Poulton J, Hanna MG, Pitceathly RDS, Taylor RW, Turnbull DM, McFarland R. . Annals of Neurology 2019, 86(2), 310-315.
• Vincent AE, White K, Davey T, Philips J, Ogden RT, Lawless C, Warren C, Hall MG, Ng YS, Falkous G, Holden T, Deehan D, Taylor RW, Turnbull DM, Picard M. . Cell Reports 2019, 26(4), 996-1009.e4.
• Ng YS, Lax NZ, Maddison P, Alston CL, Blakely EL, Hepplewhite PD, Riordan G, Meldau S, Chinnery PF, Pierre G, Chronopoulou E, Du A, Hughes I, Morris AA, Kamakari S, Chrousos G, Rodenburg RJ, Saris CGJ, Feeney C, Hardy SA, Sakakibara T, Sudo A, Okazaki Y, Murayama K, Mundy H, Hanna MG, Ohtake A, Schaefer AM, Champion MP, Turnbull DM, Taylor RW, Pitceathly RDS, McFarland R, Gorman GS. . EBioMedicine 2018, 30, 86-93.
• Grady JP, Pickett SJ, Ng YS, Alston CI, Blakely EL, Hardy SA, Feeney CL, Bright AA, Schaefer AM, Gorman GS, McNally RJ, Taylor RW, Turnbull DM, McFarland R. . EMBO Molecular Medicine 2018, 10(6), e8262.
• Rocha MC, Rosa HS, Grady JP, Blakely EL, He L, Romain N, Haller RG, Newman J, McFarland R, Ng YS, Gorman GS, Schaefer AM, Tuppen HA, Taylor RW, Turnbull DM. . Annals of Neurology 2018, 83(1), 115-130.
• Pickett S, Grady JP, Ng YS, Gorman GS, Schaefer AM, Wilson IJ, Cordell HJ, Turnbull DM, Taylor RW, McFarland R. . Annals of Clinical and Translational Neurology 2018, 5(3), 333-345.
• Ng YS, van Ruiten H, Lai HM, Scott R, Ramesh V, Horridge K, Taylor RW, Turnbull DM, Gorman GS, McFarland R, Baker MR. . Epilepsia Open 2018, 3(1), 103-108.
• Sommerville EW, Ng YS, Alston CL, Dallabona C, Gilberti M, He L, Knowles C, Chin SL, Schaefer AM, Falkous G, Murdoch D, Longman C, De Visser M, Bindoff LA, Rawles JM, Dean JCS, Petty RK, Farrugia ME, Haack TB, Prokisch H, McFarland R, Turnbull DM, Donnini C, Taylor RW, Gorman GS. . JAMA Neurology 2017, 74(6), 686-694.
• Martikainen MH, Grady JP, Ng YS, Alston CL, Gorman GS, Taylor RW, McFarland R, Turnbull DM. . European Journal of Human Genetics 2017, 25(10), 1162-1164.
• Ng YS, Taylor RW, Schaefer AM. . In: Frontiers in Diabetes. S. Karger AG, 2017, pp.55-68.
• Ng YS, Powell H, Hoggard N, Turnbull DM, Taylor RW, Hadjivassiliou M. . Neurology Genetics 2017, 3(5), e181.