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Staff Profile

Professor Mark Birch-Machin

(1) Professor of Molecular Dermatology (2) Founder and CSO of Skin Life Analytics (Spin Out Company)

Background

Mark Birch-Machin, Ph.D., is Professor of Molecular Dermatology and Associate Dean (Business Development and Commercial Interface)  at the 缅北禁地 Institute of Cellular Medicine.  Prof. Birch-Machin pursued his Post-Doctoral career at the University of Oregon (USA), INSERM Paris, University of Toronto as well as Clinical Neuroscience and Biochemistry, 缅北禁地 (1986-1995) where he held several academic positions in the Department of Dermatology (1996-current).  During this time, he was elected Treasurer of the British Society of Investigative Dermatology (BSID) and co-editor of Experimental Dermatology.  He advanced to the position of Professor of Molecular Dermatology at 缅北禁地 in 2005 and Associate Dean in 2014.

Prof. Birch-Machin’s research group focuses on the response of human skin to ultraviolet radiation particularly within the context of skin ageing and cancer, particularly involving the role of mitochondria and has published extensively including 3 different Nature journals.  He also has interest in understanding the role of mitochondrial DNA in UV-induced oxidative stress, cancer and the relationship between oxidative stress, nutritional status and skin aging as well as the science and use of sunscreens.  He has received research funding (multi-million total) from Cancer Research UK, British Skin Foundation, BBSRC, MRC, EPSRC, Wellcome Trust, NESRF, KTP, BRC, Innovate UK, NC3R, Royal Society and global commercial companies.  In addition, he is also a co-inventor on multiple patents arising from the commercialization of parts of this research, including the invention of a product that sold in over a 1,000 stores in Canada as part of a Canadian spin out company (Genesis Genomics, but company no longer exists) which Mark co-founded in 2003.  In 2010, Mark was awarded the 缅北禁地 Spirit of Entrepreneurship award and has gone on to be a co-founder of a second spin out company in 2012 which is now called PB Bioscience.  Prof. Birch-Machin has been an internationally and nationally invited keynote speaker at numerous prestigious conferences and symposia.  He has been Chair of several international Scientific Advisory Boards; member of the Cancer Research UK sunsmart advisory board, expert advisor for Clearcast, RACC and the ASA, and is a member of the grants awarding committee for the British Skin Foundation as well as the Editorial board for Experimental Dermatology.

Prof. Birch-Machin is regularly a National Press Spokesperson on ‘Sunburnt DNA,’ DNA damage, skin ageing and skin cancer risk related to his current and previous roles with national skin charities.  His research and quotes on sun awareness have appeared on multiple European and American TV segments (including 10 full TV programmes on BBC, ITN, Sky, Discovery), more than 250 radio programs, online columns, over 240 national and local UK newspapers and over 230 popular magazine articles. In addition, I have regularly and extensively contributed to the national education of sun-awareness using the popular media as well as public lectures (The Royal Institution and The Wellcome Collection). I have also given a mini-roadshow on sun-awareness to local schools, a regular Invited Public Speaker at the Discovery Museum Science Show (缅北禁地), an ‘expert’ speaker at the European Union Excellence in Cities- Specialist Bioscience Summer School (EU funded).

As the original Degree Programme Director, Prof Birch-Machin designed, created and managed the team which administers the MRes in Medical and Molecular Biosciences which in 2 years became the largest postgraduate taught programme in the Faculty of Medical Sciences. Prof Birch-Machin has various University/Faculty including Chairing the Faculty Business Opportunities committee and the Faculty Commercialisation committee. 

 Google Scholar profile:

Qualifications

July 1983 B.Sc. (Hons) II(i) Biological Sciences
specialising in biochemistry. University of East Anglia

July 1987 Ph.D. in biochemistry, University of East Anglia.

June 1997 Certificate in Learning and Teaching in Higher Education
(Faculty of Education), University of 缅北禁地 upon Tyne

Previous Positions

August 2014 Associate Dean in Development and Commercial Interface

August 2005: Professor in Molecular Dermatology
2003-2005: Reader in Molecular Dermatology
2001-2003: Senior Lecturer, Department of Dermatology, University of 缅北禁地 upon Tyne
1995 - 2001: Lecturer, Department of Dermatology, University of 缅北禁地 upon Tyne
1994 - 1995: Senior INSERM scientist (1 year appt.) Hôpital Necker, Paris, France
1992 - 1994: Lecturer, Department of Biochemistry and Genetics, University of 缅北禁地 upon Tyne
1986 - 1992: Post-Doctoral Research Associate, Division of Clinical Neuroscience, School of Neurosciences, University of 缅北禁地 upon Tyne. (including 4 months during 1989 at the University of Oregon, USA.

Memberships

Co-editor/editorial Board of International Journals:
Clinical and Experimental Dermatology (2004-2007), Experimental Dermatology (2009-current).

International Advisory/editorial Boards:
•  Expert Advisor for the Complaints and Investigations Board of the UK Advertising Standards Authority (2006-current)
• Member of the Editorial board of Experimental Dermatology (2010-current)
• Invited Member of the SunSmart Advisory Board, Cancer Research UK, April 2010-current

• Panel member for the British Skin Foundation grants committee

 

Member of the British Skin Foundation small grants award committee (2010-current)
Elected Treasurer (2002-2006) and Member of the organising and abstract selection committee of the British Society of Investigative Dermatology (BSID)which is the national body for investigative dermatology research in the UK.· Elected Committee member and Treasurer of the British Society of Investigative Dermatology 1999-2006(BSID), Director on the North Eastern Skin Research Fund.
Advisory panel member for the Science Media Centre (London)

Google Scholar:
 

Research

Research Interests

The work in my research group focuses on the cutaneous response to ultraviolet radiation (UVR) in terms of skin ageing and cancer and the molecular genetics of skin cancer. Specific areas of research are:

-Skin Ageing,Sun protection and sunscreens, environmental pollution and skin
- Mitochondria and UVR; in particular the novel approach of using mitochondrial DNA, rather than nuclear DNA, as a biomarker of cumulative UVR exposure. 
-Molecular genetics of skin cancer; in particular the role of mitochondrial DNA mutations in the development of human non-melanoma skin cancer. 
-The cutaneous response to ultraviolet radiation, including signalling mechanisms and the therapeutic use of UVR in skin disease.
-The role of mitochondria in the therapeutic action of dithranol in psoriasis
- The role of mitochondria in UV-induced oxidative stress.
- The relationship between oxidative stress, ageing and nutritional status.
- The role of mitochondrial DNA mutations in the ageing process
- Mitochondrial DNA damage and Oral Cancer
- Anti-Oxidants and free radicals (dietary and cosmetic (topical))

-Blood oxidative stress and sports training

Other Expertise

·Mitochondrial DNA and ageing.
·Mitochondrial DNA and cancer (e.g prostate cancer).

·Sunscreen Testing
·Sun Awareness

Esteem Indicators

Selected
1a. International keynote speaker: 

·         European Thyroid Cancer Research meeting, Warsaw, POLAND (August, 2001).

·         Universidad de Los Andes, Bogota, COLOMBIA (January 2004)

·         7th International Symposium, Predictive Oncology Strategies, Nice, France,  (Feb. 2004)

·         European Society of Dermatological Research (ESDR), Vienna, Austria, (Sept. 2004)

·         Sun Protection conference, Royal Society, London (2005)

·         Proctor and Gamble International Science Symposium, UK (2005)

·         European Academy of Dermatology and Venereology (EADV), Rhodes, Greece (2006)

·         European Academy of Dermatology and Venereology,Vienna (2007) (two invited keynote lectures)

·         Unilever Anti-aging symposium, Trumbull, USA (February 2008)

·         Dermatology update, Whistler, Canada (April 2008)

·         Anti-ageing skin care conference, Royal College of Physicians, London, UK, June 2008

·         Innovative anti-cancer drugs  and strategies, 1st symposium, UK 2010

·         Targeting Mitochondria, Berlin 2011

·         European Society for Photobiology, Geneva 2011

·         ESDR, Barcelona, 2011

·         Mitochondria symposium, Luebeck, Universitätsklinikum Schleswig-Holstein, Germany 2011

·         Irish Radiation Research Society Conference 2011, Sligo, Ireland

·         Targeting Mitochondria 2011 International Conference, Berlin, Germany 2011

·          5th Skin academy symposium, challenges in Skin disease management, Barcelona, Spain 2012

·         Tomatoes and Health, Royal Society of Medicine, London, UK 2012

·         American Society for Dermatologic Surgery, Atlanta, 2012

·         European Radiation Research, Dublin 2013

·         6th Asia and Oceania conference on photobiology, Sydney 2013.          

·              Chinese Dermatological mini symposium, Beijing 2013

·         FACE (international Facial Aesthetic Conference and Exhibition), keynote lecture, London 2015

·         World Congress of Dermatology, Vancouver Canada 2015-keynote lecture; skin ageing

·         World Congress of Dermatology, Vancouver Canada 2015-keynote lecture; hair and ox. stress

  • Anti-ageing Skin Care Conference, Royal College of Physicians, London 2016

  • 6th Annual World Congress of Molecular and Cell Biology, Dalian, China, 2016

  • Anti-ageing Skin Care Conference, Singapore 2016.

  • FACE (international Facial Aesthetic Conference and Exhibition), keynote lecture, London 2016.

  • EADV, Vienna 2016

  • Society of Cosmetic Chemists, Singapore 2017 

  • 7th Annual World Congress of Molecular and Cell Biology, Xian, China, 2017

  • European Society of Photobiology, Pisa, Italy 2017

  • Society of Cosmetic Chemists, London 2018

  • Ageing Asia, Singapore 2019

  • Sun Protection conference, Royal College of General Practitioners, London 2019

  • FACE (international Facial Aesthetic Conference and Exhibition), London 2019

 

1(b) National keynote speaker:

·         Biogerontology Research Symposium, June 2002.

·         Cancer Research UK Sunsmart Campaign launch, London, Feb. 2003.

·         Practical Update in Dermatology, Lumley Castle, Durham, March 2004.

·         Practical Update in Dermatology, Lumley Castle, Durham, February 2006

·         British Association of Cosmetic Doctors, March 2006

·         Health Protection Agency (Toxicology), University of Surrey, May 2006

·         70th Anniversary Oral Surgery Association of Great Britain, November 2006

·         The Academy of Pharmaceutical Sciences, London, April 2007

·         British Association of Dermatologists annual conference (BPG symposium), Birmingham 2007

·         United Kingdom Environmental Mutagen Society, 缅北禁地, June 2008

·         CPTA (cosmetic, toiletry, and perfumery association) meeting, London (April 2009)

·         Almirall annual meeting, Telford, May 2009

·         British Society for Research on Ageing, Manchester (June 2009)

·         British Cosmetic Dermatology Group, Manchester 2010

·         Public Lecture, Royal Institution, London 2011

·         Primary Care Dermatology Society, Oxford 2011

·         Cosmetics Toiletry and Perfumery Association (CPTA), London 2012

.         British Skin Foundation 20th Anniversary, London 2106

.         British Society of Investigative Dermatology, Manchester  UK, 2017 

.         London College of Fashion 2018

.         British Association of Cosmetic Dermatologists 2018

.         The Future of Cosmetics, London college of Fashion 2020


 

1 (c) Invited lectures                   a) International

·        Department of Molecular Biology, Eugene, University of Oregon USA (1989). 

·        Symposium on mitochondrial myopathies, Nijmegen, Netherlands (1990).

·        2nd International Congress on Human Mitochondrial Pathology, Rome, Italy (1992).

·        Unité de Recherches sur les Handicaps Génétiques de l'Enfant, Hôpital Necker, Paris, France (1994).

·        3rd International Congress on Human Mitochondrial Pathology, Chantilly, France (1995).

·     Department of Neurology, McMaster University Medical Center, Hamilton, Ontario, Canada

     (May 2000).

·     Mitochondria 2001, San Diego, USA (1st March, 2001)

·     Metabolism Research Instititute, Hospital for Sick Children, 555 University Avenue, Toronto, Ontario, Canada (July 2001).

·     Metabolism Research Instititute, Hospital for Sick Children, 555 University Avenue, Toronto, Ontario, Canada (August 2002).

·     Lakehead University, Northwestern Ontario Regional Cancer Centre and Genesis Genomics, Thunder Bay, Ontario, Canada (August 2002).

·     McMaster University Medical Center, Hamilton, Ontario, Canada (August 2006).

·        European Society of Dermatological Research (ESDR), Paris, Austria, (Sept. 2006).

·        European Society of Dermatological Research (ESDR), Zurich, Switzerland, (Sept. 2007).

·        European Academy of Dermatology and Venereology, Paris (2008)

·        Procter and Gamble, Cincinatti, USA 2010

·        Melanoma 2010, Sydney, Australia 2010

·        World Congress of Dermatology, Seoul, South Korea, 2011

·        Oregon Health and Science University, Portland, Oregon  2011

·        Mount Sinai Hospital, New York, USA, 2012

·        Guangxi Medical University, Nanning, China 2012

·        Procter and Gamble, Vision House Event, Abu Dhabi and Bangkok, 2012

·        Procter and Gamble, Vision House Event, Beijing 2013

 ·       University of Sydney, Bosch Lecture 2014

 ·       World Congress of Dermatology, Vancouver Canada 2015, oral session

-       3rd International Conference on UV and Skin Cancer Prevention, Melbourne, Australia 2015

-      University of Otago Christchurch, New Zealand 2015

-      University of Otago Dunedin, New Zealand 2015

-      Invitational speaker: Summit of Global Research VPs, Croda, Manchester UK, Dec 2017

-    Estee Lauder Global meeting, Long Island, New York, USA December 2017

-    Society of Cosmetic Chemists, Florida 2017

-    The Bosch Institute, University of Sydney 2018

-     L’Oreal SE Asia meeting, Singapore 2018

-     Procter and Gamble Symposium, Singapore, 2018

-     Florida International University, Miami 2018

-     Harbin Institute of Technology, Harbin, China, 2018

-    CSIRO Adelaide and Adelaide University, Australia 2019

-    CIDP, Mauritius, 2019

  

1 (d) National

·        Advanced course in neuromuscular diseases, University of 缅北禁地 upon Tyne (1988 and 1990).

·        Department of Biochemistry, University of Cambridge (1992).

·        Annual Meeting of the British Society for Investigative Dermatology, Bristol, UK (1997).

·        Department of Biological Sciences, University of East Anglia, Norwich, (1999).

·        Unilever Research, Colworth Laboratory, Bedford (2000).

·        Department of Dermatology and Photobiology, University of Dundee, 2001.

·        Northern Institute for Cancer Research, University of 缅北禁地, April 2002

·        Department of Dermatology, Hope Hospital, Salford, July 2002

·        Café Scientifique, Manchester, June 2003.

·        Café Scientifique, PEALS seminars, 缅北禁地, July 2003

·        Cancer Research UK Legacy Symposium, 缅北禁地, July 2003

·        Centre for Cutaneous Research, Barts and The London, Nov 2003.

·        The Court House Clinic Network UK, 2005.

·        RAFT Institute, London, 2006

·        British Association of Dermatologists annual conference, BSF prize, Birmingham 2007

·        Procter and Gamble, Egham, Surrey, 2008

·        Department of Pathology, RVI, 缅北禁地 2009

·        Institute of Ageing and Health, 缅北禁地 2009

·        Primary Care network, South East, UK, 2009

·        Primary Care network, Midlands UK, 2009

·        University of Bradford, School of Life Sciences, July 2009

·        Dundee University and Dermatology (Ninewells), October 2009

·        Primary Care Network, Scotland, 2010

·        National Journalist Beauty School, Royal Institution, London 2012

·        Procter and Gamble, Egham, Surrey, 2012

·        CPTA, London 2013

 ·       Bioenergetics Symposium, London, 2014

 ·      Public Lecture, University of Derby 2015

 ·      The Wellcome Collection Public Lecture, London 2015

-       Regional Phototherapy meeting Durham 2015

-      British Skin Foundation 20th Anniversary, London 2106

-     Life Sciences Student Conference, Coventry 2017

-      Bionow conference, 缅北禁地 2017

-      Skin Forum at Bath University, Bath UK, Dec 2017

-      Skin Forum at Bath University, Bath UK, Dec 2017

-      British Association of Dermatology National Trainee Skin Course, UK 2018

-      Occupational and Environmental Exposure of Skin to Chemicals conference, Dublin 2019


 2. Co-editor/editorial Board of International Journals:

Clinical and Experimental Dermatology (2004-2007), Experimental Dermatology (2009-current).

3. International Advisory/editorial Boards:
•  Expert Advisor for the Complaints and Investigations Board of the UK Advertising Standards Authority (2006-current)
• Member of the Editorial board of Experimental Dermatology (2010-current)
• Invited Member of the SunSmart Advisory Board, Cancer Research UK, April 2010-current

• Panel member for the British Skin Foundation grants committee

• Member of the Procter and Gamble Alliance Global Advisory Board 2010-2014

4. National Dermatology:
Member of the British Skin Foundation small grants award committee (2010-current)
Elected Treasurer (2002-2006) and Member of the organising and abstract selection committee of the British Society of Investigative Dermatology (BSID)which is the national body for investigative dermatology research in the UK.

Other esteem indicators

• Global Advisor for Procter and Gamble beauty (Alliance team), 2010-2014
• Global Advisory Board of Skinceuticals (New York)
• Advisor for Procter and Gamble beauty (Olay Regenerist team (Vision House), 2012-2014
• Invited member on NESTA (July 2011) to inform the Labour party policy review led by Chi Onwurah MP, Shadow Minister for Innovation and Science,
• Member of the British Skin Foundation small grants award committee (2010-current)
• Member of the Editorial board of Experimental Dermatology (2010-current)
• Co-editor of Clinical and Experimental Dermatology (2004-2007)
• Treasurer (2001-2006) of the British Society of Investigative Dermatology. 
• Member of the Abstract Selection Committee for the British Society of Investigative Dermatology (1998-2006).
• Invited Member of the SunSmart Advisory Board, Cancer Research UK, April 2010-2015.
• Member of the connectmedical working party to develop a consensus guideline for the management of actinic keratosis in primary care. London July 2004.
• Member of the national scientific site visit panel for peer review of the RAFT Research Charity, Mount Vernon Hospital, Middlesex, UK (2005-06)
• Expert Advisor for the Complaints and Investigations Department of the UK Advertising Standards Authority (2006-2008)
• Expert Advisor for the Cosmetic Toiletry and Perfumery Association (CPTA) (2008-current)
• Scientific expert for the European Food Safety Authority (EFSA) 2008-current
• Peer Reviewer for SickKids Foundation, Toronto, Canada (2010-current)
• Expert reviewer for the Natural Sciences and Engineering Research Council of Canada (NSERC) 2008-current.

• I have reviewed numerous papers for many international peer reviewed Journals including: the Biochim Biophys Acta, European Journal of Human Genetics, British Journal of Cancer, European Journal of Biochemistry, the International Journal of Biochemistry, the Journal of Investigative Dermatology, the British Journal of Dermatology, Clinical Endocrinology, International Journal of Experimental Pathology, Clinical and Experimental Dermatology, Aging Cell, Clin Chim Acta, Experimental Dermatology, British Journal of Nutrition, Photochemistry and Photobiological sciences, International Journal of Radiation Biology, Journal of Experimental & Clinical Cancer Research, Carcinogenesis, Molecular Carcinogenesis and International Journal of Cosmetic science. 

• I have also reviewed many grant applications including the MRC, Wellcome Trust, BBSRC, British Skin Foundation, Cancer Research UK, Association for International Cancer Research, Ontario Healthcare Trust (Canada) and The Sheffield Hospitals Charitable Trust and Oxford Hospitals Charitable Trust. 

• PhD thesis external examiner on many occasions over the last 15 years including Universities of Edinburgh, Bradford, Queen Mary London, Dublin, Galway, Manchester, Liverpool, Coventry, Sydney Australia.

• Designed, created and established and became Degree Programme Director of (September 2002-2007) postgraduate degree, MRes in Biomolecular Sciences, Faculty of Medical Sciences, University of 缅北禁地. This was and is still the largest Masters programme in FMS.

• Programme Director for the MRes in Biotechnology and Business Enterprise, 缅北禁地 (2010-2017)

• Director of the North Eastern Skin Research Fund (2005-current).

• Chairman of the Scientific Advisory Board for Genesis Genomics Inc., Thunder Bay, Canada (2001-2006)

• Conference Organisation: Organised and chaired the workshop on practical problems of assessment of respiratory chain activities, at the 3rd International Congress on Human Mitochondrial Pathology, Chantilly, France (1995).

• Conference Organisation: Member of the organizing committee and chaired sessions at 7 Annual meetings of the British Society of Investigative Dermatology meetings from 1999 to 2006 

Dissemination of knowledge to the general public and Engagement
Television.  -  
• Feature on Sunburnt DNA research on ITN News, May 2002.
• Discovery Health Satellite Channel, Health issues (August 2002)
• ITN Tonight with Trevor McDonald, July 2003 (full 30 min. programme)
• Makeovers from Hell, prime time ITV, August 2003
• Live expert interviews on BBC News 24 and Sky News  
• (September 2003)
• BBC Look North Live Studio Interview (5 mins), March and July 2004
• Tyne Tees Interview, March and July 2004
• Swiss National TV documentary (2004)
• Medstar TV: America’s leading Medical and Health News (August and September 2004)
• Launch of Genesis Genomics UK, ITN news and local BBC TV November 2005
• This Morning ITV- 10 minute live studio interview, Schofield and Britten, 2006
• Truth About Food, BBC2 (2007)
• Discovery Channel, USA 2007 
• Truth About Food, Discovery Channel (2007)
• Tomato/Lycopene story- Look North and Tyne Tees, May 2008
• Northern Eye, Stay Young Forever, Tyne Tees, ITV1, August 2008
• Look North news items, throughout 2009 to current
• BBC1 : Bang goes the Theory 2012
• BBC ONE show 2011 and 2018
• BBC Breakfast (Whale stories 2013 and Tiron stories 2014)
• Embarrassing Bodies 2014
• ITV Tonight  2014, 2016 and 2017
• BBC How to Look Young 2017 (with Angela Rippon)
. Channel 5-Shop Smart save money 2019
. Radio 缅北禁地 2020



- Channel 5- Shop smart –Save money 2019
 
• National Press Spokesperson on DNA damage and Skin Cancer for Cancer Research UK (Many occasions during 2002 - 2015).  Principal invited speaker at the National Press Launch of the Sunsmart campaign 2003.    
 
• 250 National Radio broadcasts. For example, BBC Radio 4 (The Material World), BBC Radio 4 (Today Programme) and Radio 2, BBC Radio Five Live, BBC Radio 缅北禁地 (Mike Parr Show, Sound Advice, The Zoo news bulletins), LBC (London), BBC Radio Cleveland, Independent Radio News network (250 national and local radio stations), BBC Radio Oxford, BBC 3 Counties Radio, Century Radio, Metro Radio, Viking Radio, BBC Radio Scotland, BBC World Service. International Radio: World Service, The International Media Line Service.

• Online Advice/News: BBC online, Channel 4 and BBC, Daily Mail online (Femail.co.uk), Hero (Higher Education and Resource Opportunities in the UK). Reddit (number 2 rated story of the day 2017) 

• 470 National Magazines and National/Regional Newspapers.  Examples are: New Scientist. Nature, National Geographic, The Sunday Telegraph, The Times, Independent, The Guardian, Daily Star, The Sun, The Daily Mail, Daily Mirror, The Evening Chronicle, The Journal, The Northern Echo, Sunday Sun, Belfast Telegraph. In addition, I have been interviewed for articles published in NOW Magazine, Marie Claire, Saga Magazine, She Magazine, Woman’s Own, Superdrug Magazine, Readers Digest, Pharmacy Magazine, Company Magazine, Good Housekeeping, Zest, Eve, Marie Claire, Vogue, Cosmopolitan, Sunday Times Travel magazine, Grazia. International Newspapers such as The New York Times, Sydney Herald.

• Science Media Centre, London. Current member of the panel of experts called on to speak to the national press.  (2003-current). 

• A Guest Expert for media workshops, 缅北禁地 April 2014-2017 and Faculty of medical Sciences 2010-2016 and Procter and Gamble scientists (2012)

•    Invited Public Speaker at the Discovery Museum Science Show, 缅北禁地 upon Tyne (2004 and 2005).

•   Media expert at the European Union Excellence in Cities Specialist Bioscience Summer School: funded by the EU social fund. University of 缅北禁地, July 2004 and 2005. 

• Invited public lecture on sun-awareness at the Wellness show, 缅北禁地 (2005)

• Mini Medical School: research talk to lay audience Autumn 2008 and 2010

• Expert speaker at Faculty wide media training workshops (2009-current)

• Global media roadshow as part of my consultancy with Procter and Gamble. Presented to audiences of 300 international journalists at various events  in Bangkok, Beverly Hills, Abu Dhabi, New York ,Beijing sharing the stage with Hollywood names such as Gwyneth Paltrow and Liv Tyler.

Funding

Research (including consultancy research contracts) have been funded over the years by:

Cancer Research UK
Cancer Research Technology
The Wellcome Trust
BBSRC
EPSRC
MRC
British Skin Foundation
Royal Society
University of 缅北禁地

NC3R

Public Health England

Innovate UK

RVI Trustees

Northern Accelerator

A large number of global commercial companies plus:

Genesis Genomics
North Star Investments
One North East
Department of Trade and Industry
PB Bioscience

 

 

Industrial Relevance

Founder and CEO of the UK subsidiary Genesis Genomics UK (this company no longer exists) 

  • I invented a product that sold in over a 1,000 stores in Canada and in another commercial application I played a key role in the PCMT prostate cancer test used as a case study in UoA5 REF return

Founder: PB Bioscience Ltd 

 

    In May 2010, awarded the 缅北禁地 Spirit of Entrepreneurship Staff award

    ·        Contract Research with global cosmetic companies over the last 15 years which have also attracted many business vouchers.

    ·        7 KTP (Knowledge Transfer partnerships)  funded projects

    ·        2 KTS (Knowledge Transfer secondments)

    ·        7 CASE Studentships with global companies

    • 缅北禁地 representative on the UK innovation round table for the Labour Shadow Cabinet (London 2011).

    • As Associate Dean and lead PI of the MRC Proximity to discovery award to FMS, I designed and lead the launch of the Exploring Life-Science partnerships showcase event first in London (London campus) in 2017 and then in Singapore (NewRIIS campus) in 2018, the latter SE Asia event with Monash University, Melbourne and the respective Malaysian campuses. 

    Patents.

    • Co-Inventor of the world-wide umbrella patent for Genesis Genomics (GGI) (2003) ((PCT: wo 02101086) complete mitochondrial genome sequences as a diagnostic tool for the health sciences)
    • Co-inventor for 2 recent (Oct 2005) GGI patents (US patent office) on Mitochondrial Rearrangements to Diagnose Sun exposure and Cancer a mtDNA deletion (2004) (Number 31726-2017) and The Use of a 3895 BP Mitochondrial DNA Deletion as a Marker for Sunlight Exposure in Human Skin (serial no. is 2,480,184 and the file no: 102222-02).
    • Co-inventor : MITOCHONDRIAL SITES AND GENES ASSOCIATED WITH PROSTATE CANCER,United States of America patent office Serial Number: 11/339,751.
    • University of 缅北禁地 upon Tyne patent no GB 0600903.9. The use of at least one agent which induces ER stress together with at least one agent which gives rise to protein disulfide isomerase inhibition for the preparation of a medicament for the treatment of cancer.
    Secured Jan 2006 Inventors: PE Lovat, CPF Redfern, MA Birch-Machin

    Teaching

    Teaching

    I have previously taught, assessed and contributed to curriculum development on three degree courses, the Pharmacology BSc., Biomedical Sciences BSc. and the MBBS.  In the 2001/2002 academic year, as I created, designed and was the Degree Programme Director for the new MRes degree. I grew the degree from 7 students to more than 80 in 3 years. During this time I secured student bursaries worth £378,800. During this time I established the MRes team and handed the directorship over to one of the team in 2006/2007 when the numbers were over 100 (the current intake is now around 250).

    Until 2106, I was the programme leader for the MRes in biotechnology and business enterprise which I created in 2007/08.

    PhD teaching
    Contribute to the new training programme for research students (implemented 2004) in particular teaching on promoting public understanding (links with media profile above) and commercialisation lectures.

    PhD Supervision: I have been involved in annually supervising/co-supervising PhD students for at least 18 years and all my students have written up and submitted within the allowed timescale of 4 years. I currently supervise 7 PhD students with 3 new students starting in September 2018.

    Examiner
    External Examiner for 30 PhD and MD students in the UK and Europe. Internal Examiner for 2-3 PhD students per year for the last 10 years.

    Assessement
    For the last 15 years I have been a PhD assessor for between 4-7 students per year.

    Deputy Programme Director for the MRes in Medical and Molecular Biosciences. 

    Strand Leader for the Mres Biotechnology and Business Enterprise.
    Module Leader for Medical Biotechnology and Enterprise (MRes)


    Administration

    Current Committees (mainly through my position as Associate Dean of Business Development
    • Chair the FMS Enterprise Team Opportunities Committee and facilitate the development of these opportunities
    • Chair the FMS Commercialisation committee which has proposed changes to the Faculty corporate engagement strategy
    • Represent FMS on the 缅北禁地 Enterprise sub-committee
    • Represent FMS on the University Equity Case Committee
    • Represent FMS on the University Founderships Management Group
    • Represent FMS on the University Engagement Committee
    • Represent FMS on the NELEP
    • Represent FMS on the Joint Business Executive with the Trusts
    • Represent FMS on the University KTP Steering Group
    • Represent FMS on the University Engagement Committee and panel member for the 2016 Engagement Fund
    • Represent FMS (Faculty Academic Champion) on the National Innovation Centre for Ageing (NICA)
    • Member of the Faculty Research and Innovation Committee (FRIC)
    • Chair the FRSC Impact sub-committee
    • Lead of the FMS Proximity to Discovery Team
    • Member of the AHSN Health Grand Challenge Steering Group
    • Degree Programme Director MRes (FMS)
    • Strand Director of the MRes in Biotechnology and Business Enterprise

    Relevant historical responsibilities
    • Member of the MRes degree programme lead team
    • Member of the curriculum committee for the MRes
    • Member of the Exam Board for the MRes
    • Faculty Research Strategy committee FRSC (leading on innovation) 2008-2016 
    • Chair of the Research Impact FRSC working group
    • Chair of the Institute of Cellular Medicine- commercialisation team 2009-2016
    • Faculty of Medical Sciences member for the University Rise Up Stakeholders Group (Careers service) 2010-2016
    • Lead of the commercialisation team in the Institute of Cellular Medicine Research Board (2009-current), 缅北禁地
    • Member of the Faculty Research Strategy committee (innovation role), 缅北禁地 2009-2016
    • Member of Graduate School Committee, Faculty of Medical Sciences, University of 缅北禁地
    • Member of the University's Learning and Teaching Strategy Review (with Professor Katharine Perera, University of Manchester).


    Publications

    • Articles

      • Hill MT, Birch-Machin MA, Sellars JD, Waddell PG. . CrystEngComm 2026, epub ahead of print.
      • Iosifidou S, Birch-Machin MA. . The PMFA Journal 2025, 12(3), 14-16.
      • Mcnish H, Mruthyunjaya SM, Figlak K, Damodaran A, Birch-Machin MA. . The FASEB journal 2025, 39(11), e70675.
      • Moor J, Bowman A, Choudhary H, Brookes J, Brieva P, Birch-Machin MA. . Cosmetics 2025, 12(3), 128.
      • Pangilinan NDT, Shalbaf O, Souza A, Chavan B, Bonn C, Birch-Machin MA. . The FASEB Journal 2025, 39(9), e70568.
      • Pangilinan ND, Shalbaf M, Souza A, Chavan B, Birch-Machin MA. . Photochemistry and Photobiology 2025, epub ahead of print.
      • Birch-Machin MA, Byng-Hall K. . Aesthetics 2024, 71-72.
      • Birch-Machin MA, Moor J, Byng-Hall K. . Aesthetics Journal 2024, 11(10), 32-35.
      • Reynolds WJ, Eje N, Christensen P, Li W-H, Daly SM, Parsa R, Chavan B, Birch-Machin MA. . FASEB BioAdvances 2023, 5(11), 470-483.
      • Wikramanayake TC, Picard M, Cheret J, Sevilla A, birch-Machin MA, Paus R. . Expert Opinions on Therapeutic Targets 2022, 26(3), 233-259.
      • Moor J, Foxcroft K, Robson G, Birch-Machin MA. . Household and Personal Care Today 2022, 17(1), 20-23.
      • Sergi S, Luscombe-Marsh N, Heilbronn LK, Birch-Machin MA, Lionetti L, Proud CG, Abeywardena MY, O'Callaghan N. . Journal of Nutrition 2021, 151(4), 810-819.
      • Dixon RV, Skaria E, Lau WM, Manning P, Birch-Machin MA, Moghimi SM, Ng KW. . Acta Pharmaceutica Sinica B 2021, 11(8), 2344-2361.
      • Zhu G, Cassidy S, Hiden H, Woodman S, Trenell M, Gunn D, Catt M, Birch-Machin MA, Anderson KN. . Nature and Science of Sleep 2021, 13, 1903-1912.
      • Langton AK, Ayer J, Griffiths TW, Rashdan E, Naidoo K, Birch-Machin MA, O'Toole EA, Watson REB, Griffiths CEM. . Journal of the European Academy of Dermatology and Venereology 2021, 35(3), 762-768.
      • Reynolds WJ, Bowman A, Hanson PS, Critchley A, Griffiths B, Chavan B, Birch-Machin MA. . FASEB BioAdvances 2021, 3(10), 855-865.
      • Oblong JE, Bowman A, Rovito HA, Jarrold BB, Sherrill JD, Black MR, Nelson G, Kimball AB, Birch-Machin M. . Aging Cell 2020, 19(10), e13248.
      • Hudson L, Rashdan E, Bonn C, Chavan B, Rawlings D, Birch-Machin MA. . FASEB Journal 2020, 34(3), 3874-3883.
      • Reynolds WJ, Hanson PS, Critchley A, Griffiths B, Chavan B, Birch-Machin MA. . FASEB Journal 2020, 34(11), 14725-14735.
      • Hanna R, Crowther J, Bulsara P, Wang X, Moore D, Birch-Machin MA. . Mitochondrion 2019, 46, 172-178.
      • Zhu G, Catt M, Cassidy S, Birch-Machin MA, Trenell M, Hiden H, Woodman S, Anderson KN. . PLoS ONE 2019, 14(12), e0226220.
      • Naidoo K, Hanna R, Birch-Machin MA. . Experimental Dermatology 2018, 27(2), 124-128.
      • Kassouf N, Kay CWM, Volkov A, Chiang S-C, birch-Machin MA, El-Khamisy SFE, Haywod RM. . Free Radical Biology and Medicine 2018, 126, 153-165.
      • Meyer DV, Green EF, Birch-Machin MA, Hatch E. . Free Radical Biology and Medicine 2018, 124, 570-571.
      • Bonn C, Naidoo K, Hine HA, Birch-Machin MA. . Household and Personal Care Today 2018, 13(2), 10-12.
      • Zakaria NNA, Okello EJ, Howes M-J, Birch-Machin MA, Bowman A. . Phytotherapy Research 2018, 32(6), 955-1144.
      • Clifford T, Bowman A, Capper T, Allerton DM, Foster E, Birch-Machin M, Lietz G, Howatson G, Stevenson EJ. . Applied Physiology, Nutrition, and Metabolism 2018, 43(3), 303-306.
      • Rodrigues R, Sniehotta F, Birch-Machin MA, Araujo-soares V. . Journal of Medical Internet Research 2017, 6(6), e112.
      • Naidoo K, Birch-Machin MA. . Cosmetics 2017, 4(1), 1-8.
      • Koogoli R, Hudson L, Naidoo K, Wilkinson S, Chavan B, Birch-Machin M. . Experimental Dermatology 2017, 26(5), 384-387.
      • Rodrigues A, Sniehotta F, Birch-Machin MA, Araujo-Soares V. . Health Psychology and Behavioral Medicine 2017, 5(1), 276-298.
      • Birch-Machin MA, Bowman A. . British Journal of Dermatology 2016, 175(Suppl. 2), 26-29.
      • Bowman A, Birch-Machin M. . Journal of Investigative Dermatology 2016, 136(5), 912-919.
      • Boulton SJ, Bowman A, Koohgoli R, Birch-Machin MA. . Experimental Dermatology 2015, 24(1), 12-13.
      • Boulton SJ, Birch-Machin MA. . The FASEB Journal 2015, 29(1), 346-353.
      • Latimer J, Lloyd J, Diffey B, Matts P, Birch-Machin MA. . Journal of Investigative Dermatology 2015, 135, 2512-2518.
      • Anderson A, Bowman A, Manning P, Birch-Machin MA, Boulton SJ. . Redox Biology 2014, 2, 1016-1022.
      • Oyewole A, Wilmot MC, Fowler M, Birch-Machin MA. . FASEB Journal 2014, 28(1), 485-494.
      • Anderson A, Bowman A, Boulton SJ, Manning P, Birch-Machin MA. . Redox Biology 2014, 2, 1016-1022.
      • Martinez-Levasseur L, Birch-Machin MA, Bowman A, Gendron D, Weatherhead E, Knell R, Acevedo-Whitehouse K. . Nature Scientific Reports 2013, 3, 2386.
      • Bowman A, Martinez-Levasseur LM, Acevedo-Whitehouse K, Gendron D, Birch-Machin MA. . Mitochondrion 2013, 13(4), 342-349.
      • Wright TJ, McKee C, Birch-Machin MA, Ellis R, Armstrong JL, Lovat PE. . Clinical and Experimental Dermatology 2013, 38(4), 421-423.
      • Bierman J, Rovito HA, Whittenbarger DJ, Tiesman JP, Combs DS, Jarrold BB, vonZglinicki T, Hatch E, Birch-Machin MA, Oblong JE. Impact of aging and environmental exposure on male facial skin biology. J Invest Dermatol 2013. In Preparation.
      • Bowman A, Martinez-Levasseur L, Acevedo-Whitehouse K, Gendron D, Birch-Machin MA. . Mitochondrion 2013, 13(4), 342-349.
      • Swalwell H, Latimer J, Haywood RM, Birch-Machin MA. . Free Radical Biology and Medicine 2012, 52(3), 626-634.
      • Rizwan M, Rodriguez-Blanco I, Harbottle A, Birch-Machin MA, Watson REB, Rhodes LE. . British Journal of Dermatology 2011, 164(1), 154-162.
      • Sood A, Salih S, Roh D, Lacharme-Lora L, Parry M, Hardiman B, Keehan R, Grummer R, Winterhager E, Andrews PW, Abbott C, Forbes K, Westwood M, Aplin JD, Ingham E, Papageoriou I, Berry M, Liu J, Dick AD, Garland RJ, Williams N, Singh R, Simon AK, Lewis M, Ham J, Roger L, Baird DM, Crompton LA, Caldwell MA, Swalwell H, Birch-Machin MA, Lopez-Castejon G, Randall A, Lin H, Suleiman MS, Evans WH, Newson R, Case CP. . Nature Nanotechnology 2011, 6(12), 824-833.
      • Challen C, Brown H, Cai C, Betts G, Paterson I, Sloan P, West C, Birch-Machin M, Robinson M. . British Journal of Cancer 2011, 104(8), 1319-1324.
      • Boulton S, Anderson A, Swalwell H, Henderson JR, Manning P, Birch-Machin MA. . Free Radical Research 2011, 45(2), 115-122.
      • Hiscutt EL, Hill DS, Martin S, Kerr R, Harbottle A, Birch-Machin M, Redfern CPF, Fulda S, Armstrong JL, Lovat PE. . Journal of Investigative Dermatology 2010, 130(9), 2250-2258.
      • Martin S, Hill DS, Paton JC, Paton AW, Birch-Machin MA, Lovat PE, Redfern CPF. . Pigment Cell and Melanoma Research 2010, 23(5), 675-682.
      • Harbottle A, Maki J, Reguly B, Wittock R, Robinson K, Parr R, Birch-Machin MA. . British Journal of Dermatology 2010, 163(6), 1291-1295.
      • Anderson AM, Aitken G, Oyewole A, Swalwell H, Henderson J, Manning P, Birch-Machin MA. . British Journal of Dermatology 2009, 160(4), 924 P29.
      • Birch-Machin M, Henderson J, Oyewole A, Anderson A, Boulton SJ, Manning P, Birket M, McNeil C, Swalwell H. . Journal of Investigative Dermatology 2009, 129, S36-S36.
      • Birket MJ, Passos JF, von Zglinicki T, Birch-Machin MA. . Journal of Investigative Dermatology 2009, 129(6), 1361-1366.
      • Henderson JR, Swalwell H, Boulton S, Manning P, McNeil CJ, Birch-Machin MA. . Free Radical Research 2009, 43(9), 796-802.
      • Hill DS, Martin S, Armstrong JL, Flockhart R, Tonison JJ, Simpson DG, Birch-Machin MA, Redfern CPF, Lovat PE. . Clinical Cancer Research 2009, 15(4), 1192-1198.
      • Ahmed S, Passos JF, Birket MJ, Beckmann T, Brings S, Peters HH, Birch-Machin MA, von Zglinicki TW, Saretzki GC. . Journal of Cell Science 2008, 121(7), 1046-1053.
      • Lovat PE, Corazzari M, Armstrong JL, Martin S, Pagliarini V, Hill DS, Brown A, Piacentini M, Birch-Machin MA, Redfern CPF. . Cancer Research 2008, 68(13), 5363-5369.
      • Hill DS, Armstrong JL, Birch-Machin MA, Lovat PE. . British Journal of Dermatology 2008, 158(4), 909 Abstract P51.
      • Birket MJ, Birch-Machin MA. . Aging Cell 2007, 6(4), 557-564.
      • Parr RL, Jakupciak JP, Birch-Machin MA, Dakubo GD. . Expert Opinion on Medical Diagnostics 2007, 1(2), 169-182.
      • Birket MJ, Birch-Machin MA, Ahmed S, Vonzglinicki T, Saretzki G. . British Journal of Dermatology 2007, 156(5), 1105-1105.
      • Corazzari, M., Lovat, P.E., Armstrong, J.L., Fimia, G.M., Hill, D.S., Birch-Machin, M.A., Redfern, C.P.F., Piacentini, M. . British Journal of Cancer 2007, 96(7), 1062-1071.
      • Passos JF, Saretzki G, Ahmed S, Nelson G, Richter T, Peters H, Wappler I, Birket MJ, Harold G, Schaeuble K, Birch-Machin MA, Kirkwood TBL, von Zglinicki T. . PLoS Biology 2007, 5(5), 1138-1151.
      • Vatve M, Ortonne J-P, Birch-Machin MA, Gupta G. . British Journal of Dermatology 2007, 157(2), 21-24.
      • Aitken GR, Henderson JR, Chang S-C, McNeil CJ, Birch-Machin MA. . Clinical and Experimental Dermatology 2007, 32(6), 722-727.
      • Arck PC, Overall R, Spatz K, Liezman C, Handjiski B, Klapp BF, Birch-Machin MA, Peters EMJ. . FASEB Journal 2006, 20(9), 1567-1569.
      • Krishnan KJ, Birch-Machin MA. . Journal of Investigative Dermatology 2006, 126(2), 408-415.
      • Parr RL, Dakubo GD, Crandall KA, Maki J, Reguly B, Aguirre A, Wittock R, Robinson K, Alexander JS, Birch-Machin MA, Abdel-Malak M, Froberg MK, Diamandis EP, Thayer RE. . Journal of Molecular Diagnostics 2006, 8(3), 312-319.
      • Harbottle A, Birch-Machin MA. . British Journal of Cancer 2006, 94(12), 1887-1893.
      • McGill A, Frank A, Emmett N, Turnbull DM, Birch-Machin MA, Reynolds NJ. . FASEB Journal 2005, 19(8), 1012-1014.
      • Krishnan KJ, Harbottle A, Birch-Machin MA. . Journal of Investigative Dermatology 2004, 123(6), 1020-1024.
      • Durham SE, Krishnan KJ, Betts J, Birch-Machin MA. . British Journal of Cancer 2003, 88(1), 90-95.
      • Thayer R, Wittock R, Parr R, Zullo S, Birch-Machin MA. . Experimental Gerontology 2003, 38(5), 567-571.
      • Thayer RE, Wittock R, Parr R, Zullo S, Birch-Machin MA. . Experimental Gerontology 2003, 38(5), 567-571.
      • Flanagan N, Ray AJ, Todd C, Birch-Machin MA, Rees JL. . Journal of Investigative Dermatology 2001, 117(5), 1314-1317.
      • Hatta N, Dixon C, Ray AJ, Phillips SR, Cunliffe WJ, Dale M, Todd C, Meggit S, Birch-Machin MA, Rees JL. . Journal of Investigative Dermatology 2001, 116(4), 564-570.
      • Ray AJ, Turner R, Nikaido O, Rees JL, Birch-Machin MA. . Journal of Investigative Dermatology 2000, 115(4), 674-679.
      • Flanagan N, Healy E, Ray A, Philips S, Todd C, Jackson IJ, Birch-Machin MA, Rees JL. . Human Molecular Genetics 2000, 9(17), 2531-2537.
      • Healy E, Flannagan N, Ray A, Todd C, Jackson IJ, Matthews JNS, Birch-Machin MA, Rees JL. . Lancet 2000, 355(9209), 1072-1073.
      • Birch-Machin MA, Taylor RW, Cochran B, Ackrell BAC, Turnbull DM. . Annals of Neurology 2000, 48(3), 330-335.
      • Harding RM, Healy E, Ray AJ, Ellis NS, Flanagan N, Todd C, Dixon C, Sajantila A, Jackson IJ, Birch-Machin MA, Rees JL. . American Journal of Human Genetics 2000, 66(4), 1351-1361.
      • Pinard JM, Marsac C, Barkaoui E, Desguerre I, Birch-Machin M, Reinert P, Ponsot G. . Archives de Pediatrie 1999, 6(4), 421-426.
      • Korge BP, Healy E, Traupe H, Punter C, Mauch C, Hamm H, Birch-Machin MA, Belgaid CE, Stephenson AM, Holmes SC, Darlington S, Messenger AG, Rees JL, Munro CS. . Experimental Dermatology 1999, 8(4), 310-312.
      • Tabata H, Nagano T, Ray AJ, Flanagan N, Birch-Machin MA, Rees JL. . Journal of Investigative Dermatology 1999, 113(6), 972-976.
      • Schioth HB, Phillips SR, Rudzish R, Birch-Machin MA, Wikberg JES, Rees JL. . Biochemical and Biophysical Research Communications 1999, 260(2), 488-491.
      • Korge BP, Hamm H, Jury CS, Traupe H, Irvine AD, Healy E, Birch-Machin M, Rees JL, Messenger AG, Holmes SC, Parry DAD, Munro CS. . Journal of Investigative Dermatology 1999, 113(4), 607-612.
      • M. Birch-Machin and J. Rees. Mitochondrial DNA deletions in human skin reflect photo- rather than chronologic aging - Reply. Journal of Investigative Dermatology 1998, 111, 710-710.
      • Birch-Machin MA, Tindall M, Turner R, Haldane F, Rees JL. . Journal of Investigative Dermatology 1998, 110(2), 149-152.
      • Smith R., Healy E., Siddiqui S., Flannagan N., Steijlen P., Rosdahl I., Rogers S., Turner R., Jackson I.J., Birch-Machin M.A. and Rees J.L. Melanocortin 1 receptor variants in an Irish population. J Invest Dermatol 1998, 111, 101-104.
      • Rees J.L., Phillips S., Birch-Machin M.A., Healy E., Jackson I., Todd C., Flanagan N. and Smith R. Genetics of the MC1R: sex and sun!. Experimental Dermatology 1998, 7 (4), 228.
      • B. P. Korge, E. Healy, C. S. Munro, C. Punter, M. Birch-Machin, S. C. Holmes, S. Darlington, H. Hamm, A. G. Messenger, J. L. Rees and H. Traupe. A mutational hotspot in the 2B domain of human hair basic keratin 6 (hHb6) in monilethrix patients. Journal of Investigative Dermatology 1998, 111, 896-899.
      • Birch-Machin M.A, Healy E, Turner R, Haldane F, Belgaid C.E, Darlington S, Stephenson A.M, Munro C, Messenger AG, Rees J.L. Mapping of monilethrix to the type II keratin gene cluster at chromosome 12q13 in 3 new families including one with variable expressivity. British Journal of Dermatology 1997, 137, 339-343.
      • Taylor R.W., Birch-Machin M.A., Schaeffer J., Taylor L., Shakir R., Ackrell B.A.C., Bindoff L.A., Jackson M.J. and Turnbull D.M. Deficiency of complex II of the mitochondrial respiratory chain in two sisters with late onset optic atrophy and ataxia. Ann Neurol 1996, 39, 224-232.
      • R. W. Taylor, M. A. BirchMachin, J. Schaefer, L. Taylor, R. Shakir, B. A. C. Ackrell, B. Cochran, L. A. Bindoff, M. J. Jackson, P. Griffiths and D. M. Turnbull. Deficiency of complex II of the mitochondrial respiratory chain in late onset optic atrophy and ataxia. Annals of Neurology 1996, 39, 224-232.
      • Birch-Machin MA (corresponding author), Marsac C, Ponsot G, Parfait P, Taylor RW, Rustin P, and Munnich A.(1996). Biochemical Investigations and Immunoblot analysis of two unrelated patients with an isolated deficiency in complex II of the mitochondrial respiratory chain. Biochem. Biophys. Res. Commun 1996, 220, 57-62.
      • Birch-Machin, M.A., Marsac, C., Ponsot, G., Parfait, B., Taylor, R.W., Rustin, P. and Munnich, A. Biochemical investigations and immunoblot analyses of two unrelated patients with an isolated deficiency in complex II of the mitochondrial respiratory chain. Biochem. Biophys. Res. Commun 1996, 220, 57-62.
      • Birch-Machin MA (corresponding author), Briggs H, Saborido AA, Bindoff LA and Turnbull DM (1994). An evaluation of the measurement of the activities of complexes I-IV in the respiratory chain of human skeletal muscle mitochondria. Biochem Med Metab Biol 1996, 220, 57-62.
      • Bourgeron T, Rustin P, Chretien D, Birch-Machin MA, Bourgeois M, Viegas-Péquinot E, Munnich A and Rötig A. Mutation of a nuclear succinate dehydrogenase gene results in mitochondrial respiratory chain deficiency. Nature Genetics 1995, 11, 144-148.
      • Taylor RW, Birch-Machin MA, Bartlett K, Lowerson SA, Turnbull DM. The control of mitochondrial oxidations by complex III in rat muscle and liver mitochondria. Implications for our understanding of mitochondrial cytopathies in man. J Biol Chem 269 269 3523-3528 1994.
      • Taylor, R.W., Birch-Machin, M.A., Bartlett, K., Lowerson, S.A., and Turnbull, D.M. The control of mitochondrial oxidations by complex III in rat muscle and liver mitochondria: implications for our understanding of mitochondrial cytopathies in man. J. Biol. Chem 1994, 269, 3523-3528.
      • Birch-Machin MA, Briggs H, Saborido AA, Bindoff LA and Turnbull DM. An evaluation of the measurement of the activities of complexes I-IV in the respiratory chain of human skeletal muscle mitochondria. Biochem Med Metab Biol 1994, 51, 35-42.
      • Birch-Machin MA, Farnsworth L, Ackrell BAC, Cochran B, Jackson S, Bindoff LA, Aitken A, Diamond AG and Turnbull DM. The sequence of the flavoprotein subunit of bovine heart succinate dehydrogenase. J Biol Chem 1992, 267, 11553-11558.

    • Book Chapters

      • Bowman A, Birch-Machin MA. . In: Volkmar Weissig and Marvin Edeas, ed. Mitochondrial Medicine Volume 3: Manipulating Mitochondria and Disease- Specific Approaches. New York, NY, USA: Humana, 2021, pp.345-356.
      • Bowman A, Birch-Machin MA. . In: Weissig, V; Edeas, M, ed. Mitochondrial Medicine. New York: Springer, 2015, pp.379-388.
      • Martinez-Levasseur LM, Gendron D, Knell RJ, O'Toole EA, Singh M, Bowman A, Birch-Machin MA, Acevedo-Whitehouse K. . In: McGraw-Hill Education Yearbook of Science and Technology Textbook. McGraw-Hill Professional, 2014, pp.325-327.
      • Birch-Machin MA, Harbottle A. . In: Haywood, R, ed. Photochemistry and Photobiology. 2013. In Press.
      • Birch-Machin MA. . In: Chilcott, R; Price, S, ed. Principles and Practice of Skin Toxicology. London, UK: John Wiley and Sons, 2008, pp.51-69.
      • Birch-Machin MA. . In: Will, Y; Dykens, JA, ed. Drug-induced Mitochondrial Dysfunction. New Jersey, USA: John Wiley and Sons, 2008, pp.386-397.
      • Birch-Machin MA, Turnbull DM. . In: Liza A. Pon, Eric A. Schon, ed. Mitochondria. San Diego, California; London: Academic Press, 2001, pp.97-117.
      • Healy E, Birch-Machin MA, Rees JL. . In: Cone, R.D, ed. The Melanocortin Receptors. New Jersey, USA: Humana Press Inc, 2000, pp.341-350.
      • Birch-Machin MA, Jackson S, Singh-Kler R and Turnbull DM. Study of skeletal muscle mitochondrial dysfunction. In: Methods in Toxicology. 1993, pp.51-69.
      • Birch-Machin MA, Jackson S, Singh-Kler R and Turnbull DM. Study of skeletal muscle mitochondrial dysfunction. In: Methods in Toxicology. 1993, pp.51-69.
      • Birch-Machin MA, Howell N and Turnbull DM. Defects at coupling site II. In: Methods in Toxicology. 1993, pp.324-336.

    • Conference Proceedings (inc. Abstracts)

      • Bowman A, Oblong JE, Rovito HA, Birch-Machin MA. . In: Journal of Investigative Dermatology. 2018, Orlando, Florida: Elsevier.
      • Boulton SJ, Birch-Machin M. . In: British Society of Investigative Dermatology. 2015, Southampton, UK: Wiley-Blackwell.
      • Bowman A, Birch-Machin MA, Lietz G. . In: International Society of Antioxidants in Nutrition and Health 15th International Antioxidants Congress. 2015, Paris, France.
      • Latimer JA, Birch-Machin MA. . In: British Society of Investigative Dermatology Annual Meeting. 2014, 缅北禁地 upon Tyne, UK: Wiley-Blackwell.
      • Boulton SJ, Birch-Machin M. . In: British Society of Investigative Dermatology Annual Meeting. 2014, 缅北禁地 upon Tyne, UK: Wiley-Blackwell.
      • Bosch C, Lietz G, Birch-Machin M. . In: British Society of Investigative Dermatology Annual Meeting. 2014, 缅北禁地 upon Tyne: Wiley-Blackwell.
      • Bowman A, Anderson A, Manning P, Birch-Machin M. . In: British Society of Investigative Dermatology Annual Meeting. 2014, 缅北禁地 upon Tyne: Wiley-Blackwell.
      • Rodrigues AM, Sniehotta FF, Birch-Machin MA, Araujo-Soares VL. . In: Annals of Behavioral Medicine. 2014, Springer.
      • Asim M, Liu OH, Okello E, Birch-Machin M, Foltz M, Lietz G. . In: Nutrition Society Annual Summer Meeting. 2013, 缅北禁地, UK: Cambridge University Press.
      • Latimer JA, Russell EV, Birch-Machin MA. . In: 42nd Annual Meeting of the European Society for Dermatological Research (ESDR). 2012, Venice, Italy: Nature Publishing Group.
      • Bowman A, Martinez-Levasseur L, Acevedo-Whitehouse K, Gendron D, Birch-Machin M. . In: British Society for Investigative Dermatology Meeting. 2012, Exeter: Wiley-Blackwell.
      • Russell EV, Latimer JA, Oyewole A, Birch-Machin MA. . In: 42nd Annual Meeting of the European Society for Dermatological Research (ESDR). 2012, Venice, Italy: Nature Publishing Group.
      • Oyewole A, Bowman A, Rogers T, Birch-Machin MA. . In: Annual Meeting of the British Society for Investigative Dermatology. 2011, Manchester, UK: British Journal of Dermatology: Wiley-Blackwell.
      • Swalwell H, Boulton S, Manning P, McNeil C, Birch-Machin M. . In: Journal of Investigative Dermatology: 41st Annual Meeting of the European Society for Dermatological Research. 2011, Barcelona, Spain: Nature Publishing Group.
      • Oyewole A, Birket MJ, Birch-Machin MA. . In: British Journal of Dermatology: Annual Meeting of the British Society for Investigative Dermatology. 2010, Edinburgh, UK: Wiley-Blackwell Publishing Ltd.
      • Wilmot MC, Swalwell H, Oyewole A, Birket MJ, Lietz G, Birch-Machin MA. . In: British Journal of Dermatology: Annual Meeting of the British Society for Investigative Dermatology. 2010, Edinburgh, UK: Wiley-Blackwell.
      • Oyewole A, Birket MJ, Levett D, Anderson M, Swalwell H, Birch-Machin MA. . In: British Journal of Dermatology: British Society for Investigative Dermatology Annual Meeting. 2009, Royal Agricultural College, Cirencester, UK: Wiley-Blackwell Publishing Ltd.
      • Lovat P, Armstrong J, Martin S, Hill D, Pagliarini V, Piacentini M, Redfern C, Birch-Machin MA. . In: Journal of Investigative Dermatology: 39th Annual European Society for Dermatological Research. 2009, Budapest, Hungary: Nature Publishing Group.
      • Harbottle A, Birch-Machin M, Maki J, Reguly B, Dakubo G, Davies C, Parr R. . In: Journal of Investigative Dermatology: International Investigative Dermatology Meeting. 2008, Kyoto, Japan: Nature Publishing Group.
      • Rizwan M, Rodriguez-Blanco I, Harbottle A, Birch-Machin M, Watson REB, Rhodes LE. . In: British Journal of Dermatology: Annual Meeting of the British Society for Investigative Dermatology. 2008, Oxford, UK: Wiley-Blackwell Publishing Ltd.
      • Birket MJ, Passos JF, von Zglinicki T, Birch-Machin MA. . In: British Society for Investigative Dermatology Annual Meeting. 2008, University of Oxford, UK: British Journal of Dermatology: Blackwell Publishing.
      • Levett D, Martin S, Lovat PE, Birch-Machin MA. . In: British Journal of Dermatology: Annual Meeting of the British Society for Investigative Dermatology. 2008, Oxford, UK: Wiley-Blackwell Publishing Ltd.
      • Lovat PE, Martin S, Armstrong JL, Redfem CPF, Birch-Machin MA. . In: The Journal of Investigative Dermatology: International Investigative Dermatology Meeting. 2008, Kyoto, Japan: Nature Publishing Group.
      • Martin S, Hill DS, Armstrong JL, Birch-Machin MA, Redfern CPF, Lovat PE. . In: Annual Meeting of the British Society for Investigative Dermatology. 2008, University of Oxford: British Journal of Dermatology: Wiley-Blackwell.
      • Hill DS, Armstrong JL, Birch-Machin MA, Lovat PE. . In: British Society for Investigative Dermatology Annual Meeting. 2007, Nottingham, Nottinghamshire, UK: British Journal of Dermatology: Wiley-Blackwell Publishing Ltd.
      • Lovat P, Redfern CPF, Birch-Machin MA. . In: The Journal of Investigative Dermatology:37th Annual Meeting of the European Society for Dermatological Research. 2007, Zurich, Switzerland: Nature Publishing Group.
      • Lovat PE, Redfern CPF, Birch-Machin MA. . In: British Society for Investigative Dermatology Annual Meeting. 2007, University of Nottingham, Nottingham, England: British Journal of Dermatology: Wiley-Blackwell Publishing Ltd.
      • Lovat, P., Harbottle, A., Corazzari, M., Armstrong, J., Piacentini, M, Redfern, C.P.F., Birch-Machin, M.A. . In: Annual Meeting of the British Society for Investigative Dermatology. 2006, University of Manchester: British Journal of Dermatology, Wiley-Blackwell.
      • Aitken G, Harbottle A, Birch-Machin MA. . In: British Journal of Dermatology: Annual meeting of the British Society for Investigative Dermatology. 2003, Southampton, UK: Wiley-Blackwell Publishing Ltd.
      • McGill A, Frank A, Emmett N, Birch-Machin MA, Reynolds NJ. . In: British Journal of Dermatology: Annual meeting of the British Society for Investigative Dermatology. 2003, Southampton, UK: Wiley-Blackwell Publishing Ltd.
      • Krishnan KJ, Lusher M, Lindey J, Birch-Machin MA. . In: British Journal of Dermatology: Annual meeting of the British Society for Investigative Dermatology. 2003, Southampton, UK: Wiley-Blackwell Publishing Ltd.
      • Ray A, Turner R, Rees J, Birch-Machin M. Ultraviolet radiation exposure and the spectrum of mitochondrial DNA deletions in human skin. In: JOURNAL OF INVESTIGATIVE DERMATOLOGY. 1999.
      • Korge B, Hamm H, Traupe H, Irvine A, Healy E, Birch-Machin M, Rees J, Messenger A, Holmes S, Jury C, Munro C. . In: Journal of Investigative Dermatology. 1999, Nature Publishing Group.
      • Ellis NS, Ray AJ, Healy E, Todd C, Flanagan N, Harding R, Jackson I, Birch-Machin MA, Rees JL. . In: Journal of Investigative Dermatology. 1999, Nature Publishing Group.
      • Flanagan N, Healy E, Philips S, Todd C, Ray A, Hair L, Matthews J, Jackson I, Birch-Machin M, Rees J. . In: Annual Meeting for the European Society for Dermatological Research. 1999, Nature Publishing Group.
      • Rees JL, Birch-Machin M, Flanagan N, Healy E, Phillips S, Todd C. . In: Cutaneous Neuroimmunomodulation: The Proopiomelanocortin System. 1999, Münster, Germany: Wiley-Blackwell Publishing, Inc.
      • Rees JL, Birch-Machin M, Flanagan N, Healy E, Phillips S, Todd C. . In: Cutaneous Neuroimmunomodulation: The Proopiomelanocortin System. 1999, Münster, Germany: New York Academy of Sciences.
      • Korge B, Hamm H, Jury C, Traupe H, Irvine A, Healy E, Birch-Machin M, Rees J. . In: Journal of Investigative Dermatology. 1999, Nature Publishing Group.

    • Editorial

      • Birch-Machin MA. . British Journal of Cancer 2005, 93(3), 271-272.

    • Letters

      • Harbottle A, Krishnan KJ, Birch-Machin MA. . Journal of Investigative Dermatology 2004, 122(6), 1518-1521.
      • Krishnan K, Lindsey JC, Lusher ME, Lowes S, Birch-Machin MA. . Journal of Investigative Dermatology 2003, 120(6), 981-982.
      • Healy E, Todd C, Jackson IJ, Birch-Machin M, Rees JL. . Journal of Investigative Dermatology 1999, 112(4), 512-513.
      • Birch-Machin M, Rees J. Mitochondrial DNA deletions in human skin reflect photo- rather than chronologic aging - Reply. JOURNAL OF INVESTIGATIVE DERMATOLOGY 1998, 111(4), 710-710.

    • Reviews

      • Birch-Machin M. . Dermatology Focus 2019, 37(4), 1-14.
      • Stout R, Birch-Machin MA. . Biology 2019, 8(2), 1-12.
      • Hudson L, Bowman A, Rashdan E, Birch-Machin MA. . Maturitas 2016, 93, 34-40.
      • Oyewole A, Birch-Machin M. . Experimental Dermatology 2015, 24(9), 651-654.
      • Kandola K, Bowman A, Birch-Machin MA. . International Journal of Cosmetic Science 2015, 37(Supplement S2), 1-8.
      • Oyewole A, Birch-Machin MA. . FASEB Journal 2015, 29(12), 4766-4771.
      • Tulah AS, Birch-Machin MA. . Mitochondrion 2013, 13(5), 444-453.
      • Birch-Machin MA, Russell EV, Latimer JA. . British Journal of Dermatology 2013, 169(Suppl. 2), 9-14.
      • Birch-Machin MA, Swalwell H. . Mutagenesis 2010, 25(2), 101-107.
      • Dakubo GD, Jakupciak JP, Birch-Machin MA, Parr RL. . Cancer Cell International 2007, 7(2).
      • Dakubo GD, Jakupciak JP, Birch-Machin MA, Parr RL. Clinical implications and utility of field cancerization. CANCER CELL INTERNATIONAL 2007, 7, -.
      • Birch-Machin MA. . Clinical and Experimental Dermatology 2006, 31(4), 548-552.
      • Parr RL, Dakubo GD, Thayer RE, McKenney K, Birch-Machin MA. . Human Genomics 2006, 2(4), 252-257.
      • Birch-Machin MA. . Clinical and Experimental Dermatology 2000, 25(2), 141-146.