缅北禁地

ORCID

https://orcid.org/0009-0005-9103-7996

Current position

Postdoctoral Research Associate, Wolfson Childhood Cancer Research Centre - Leukaemia Epigenomics and Enhancer Dysregulation (LEGEND) group led by Dr Lisa Russell

Experience/Expertise

Molecular biology:

• Plasmid cloning
• RNA, DNA and protein analysis
• CRISPR systems

Cell biology:

• 2D cell culture
• 3D cell culture
• Primary cell culture
• Lentiviral transduction/generation of transgenic cells

Bioinformatics:

• Transcriptomics
• Proteomics
• Epigenomics
• R/Linux

Qualifications

2023: PhD Molecular Oncology (CRUK funded), 缅北禁地

2016: MSc Translational Oncology, University of Hull

2013: BSc Biomedical Science, University of Warwick

Previous positions

2023 - 2025: Scientist, Newcells Biotech Ltd

2019 - 2023: Postgraduate Researcher, 缅北禁地 Centre for Cancer Urology Research/Solid Tumour Target Discovery group

2016 - 2019: Scientific Officer, CRUK Manchester Institute Clinical & Experimental Pharmacology group (now part of the CRUK National Biomarker Centre)

Professional memberships

British Association for Cancer Research (BACR)

European Association for Cancer Research (EACR)

• Articles

  • Brittain N, Paschalis A, Nelson R, Adamson B, Walker L, Duncan R, Smith GR, McGill S, Burchmore RJ, Bogdan D, Jiménez-Vacas JM, Welti J, Yuan W, Robson CN, Rescigno P, Luzzi S, Sharp A, de Bono J, Gaughan L. Splicing factor TRA2B enhances synthesis of androgen receptor variant AR-V7 in prostate cancer cells. The Journal of Clinical Investigation 2026, 136(7).
  • Paschalis A, Figueiredo I, Bogdan D, Lundberg A, Santos R, Gurel B, Taha T, Longoria O, Ferreira A, Bertan C, Brittain N, Nelson R, Walker L, Neeb A, Welti J, Yuan W, Mitsopoulos C, Plymate SR, Haffner MC, Sowalsky AG, Carreira S, Sharp A, Gaughan L, de Bono J. Androgen receptor splice variant 7 expression levels distinguish AR-mutated from nonmutated metastatic castration-resistant prostate cancers. The Journal of Clinical Investigation 2026, 136(7).
  • Walker L, Duncan R, Adamson B, Kendall H, Brittain N, Luzzi S, Jones D, Chaytor L, Peel S, Crafter C, O'Neill DJ, Gaughan L. . Molecular Cancer Research 2024, 22(12), 1128-1142.
  • Adamson B, Brittain N, Walker L, Duncan R, Luzzi S, Rescigno P, Smith GR, McGill S, Burchmore RJS, Willmore E, Hickson I, Robson CN, Bogdan D, Jimenez-Vacas JM, Paschalis A, Welti J, Yuan W, McCracken SR, Heer R, Sharp A, de Bono J, Gaughan L. . Journal of Clinical Investigation 2023, 133(22), e169200.
  • Poujade FA, Mannion A, Brittain N, Theodosi A, Beeby E, Leszczynska K, Hammond E, Greenman J, Cawthorne C, Pires IM. WSB-1 regulates the metastatic potential of hormone receptor negative breast cancer. British Journal of Cancer 2018, 118(9), 1229–1237.