Translational and Clinical Research
We strive to improve best practices and boost the resources that support our established reputation in research.
Benefit led research
We have a track record of designing and delivering clinical and translational research for patient benefit.
Our focal disease communities have developed tools and approaches to become more 'trial-ready'. Our Centre is exploring the application of these resources and good practices. This will support other fields in moving closer to robust clinical trials.
Our goal is to advance research strategies and infrastructure to boost discovery science. We place an emphasis on supporting the translation of promising research into trials and onwards into clinic.
Enhancing our capacity
Our doctors and researchers are committed to improving the lives of those with rare diseases. We aim to build our capacity of core activities relevant to translational research, including:
- stratifying patient cohorts. This includes setting up and supporting rare disease patient registries to support clinical trial feasibility and recruitment.
- improving the design and delivery of paediatric clinical trials
- capitalising on our long track record of leading European and global-level initiatives. This will allow us to disseminate and embed good practices in 'grass roots' research.
- leveraging our experience of clinical trials in gene and other advanced therapies
- making research data more FAIR (Findable, Accessible, Interoperable, and Reusable) through use of include data dictionaries, data standards and AI tools.
These goals are supported by our collaboration with private companies (see For Companies).
We also have experience in investigator-initiated trials, including expertise on repurposing medicines (for instance in ).
